| Gene Name | GRAP |
|
| Specie | Homo sapiens | |
| Full Name | GRB2 related adaptor protein | |
| Also known as | DFNB114 | |
| Coordinate | chr17:19020656-19046957 | |
| Strand | - | |
| Gene summary | This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| GRAPP1 | chr1:209173019-209174676 | + |
Intergenic |
ENSG00000228081 | UCSC |
| >NM_006613.4 |
| GAGCCCAGCTGCTGGAGCCCCGAGCAGCGGCATGGAGTCCGTGGCCCTGTACAGCTTTCAGGCTACAGAGAGCGACGAGCTGGCCTTCAACAAGGGAGACACACTCAAGATCCTGAACATGGAGGATGACCAGAACTGGTACAAGGCCGAGCTCCGGGGTGTCGAGGGATTTATTCCCAAGAACTACATCCGCGTCAAGCCCCATCCGTGGTACTCGGGCAGGATTTCCCGGCAGCTGGCCGAAGAGATTCTGATGAAGCGGAACCATCTGGGAGCCTTCCTGATCCGGGAGAGTGAGAGCTCCCCAGGGGAGTTCTCTGTGTCTGTGAACTATGGAGACCAGGTGCAGCACTTCAAGGTGCTGCGTGAGGCCTCGGGGAAGTACTTCCTGTGGGAGGAGAAGTTCAACTCCCTCAACGAGCTGGTCGACTTCTACCGCACCACCACCATCGCCAAGAAGCGGCAGATCTTCCTGCGCGACGAGGAGCCCTTGCTCAAGTCACCTGGGGCCTGCTTTGCCCAGGCCCAGTTTGACTTCTCAGCCCAGGACCCCTCGCAGCTCAGCTTCCGCCGTGGCGACATCATTGAGGTCCTGGAGCGCCCAGACCCCCACTGGTGGCGGGGCCGGTCCTGCGGGCGCGTTGGCTTCTTCCCACGGAGTTACGTGCAGCCCGTGCACCTGTGAGCAGCCCGGCGGCCGATCTGGCCAACGGGCCTttttacaggaactgaggtccagagaggacatggacacccccagctctgtcagagtcacacggggctcagtggacggccttggactgaacgtgggctcctaactgcctccggccgctctgcacaAACTGGGATGGCCCAGGTCCCCCAGCAAGGGTACCCAGCAAGGGTAGCTCCGGGGCTTCCTGGCTGGTTGCTTTCCATTGGCTGCCAGCTGTGTGACACCACAGGGCGGAGTCTGTGGAGGCCCCGCCCACCTCCTCTTGTCAATGGCCCCATCTGCCAGGAAGGTTGAGGACTCCCAGGTTTCACCCACTGGAGGCTCAACCTAAGGAACCCTGGCCATGGTGGGTGGGTTCACCTTGGGCTGACCACCCACTGGGCCTGCCTGCCCCTCCCTCAAAAGGCCCCTGGAGTTGTTCAGGCTGTTGGGAGGTGGCTCAGCCTCGAAGGACAGACTGCACACCTGTTGACCTAAACTCACTGGACAGACTCCAGGTGGACACCAACTCCTCAACAGCCCCATGACTTCAGCTCCACCTGGGGCACCCAGCACCCCACCACAGGGCTAGAGGCCCTAAGACCCTGAAAAAGGGGCGGGCAGTAGGGAAGGTGGAGGCACACTCCTCTTCTGTTGGACAGGTGAGCTCTGAGGGCAAGCCCTGGGCCCAGCCACGCAGAGACCCTGGCTGCCCTGGCTCTTGTTTGTTTAGGCCCAGGTTCTGCCCAGACCGGGGCCCAGCAGAGCTCTCAGGAGGCTGAGAAACCTCCAGGGCAGACAGAAAGTTGGGGCCAGAGCTAGGTTTTAGAGATCCTACAGGATCCCACATGGGACGGCTACCTAGGTGGGGCACGGCCCCTACCCGAGAACAGGAGGGTCCTCCAGAGAATGTGCCATGATCAGGGATATGAGCAGGGCCTGCCCAGAGCCTGGGCACCTTTGGGAGAGGGAAAAGTGAGGTGGGACTTGGAAAGGCTTTGAACGCCAGGCTGATGGTTgagggatggtgggcagggagggagggCGAAGAGGCTCCCTCTGGCATTTGGGAGCCGGTGGGTGGAGGGAGGAGCCCTTGGAGGTGGCTGCAGTCCCTTAATGGGGGGCCTTGCTCTGGGCATGTGGGGCTCTTCCTCCATCcagagctggcccaagacccttagaaccctgagtgctggcaaatctcactgctcctgacccagcctgtgtattcaaaacgaaaacagtaaaaccaacatcaggatgtccgtcagaaatctaattttccttccaa |