| Gene Name | Adam12 |
|
| Specie | Mus musculus | |
| Full Name | a disintegrin and metallopeptidase domain 12 (meltrin alpha) | |
| Also known as | Mltna | |
| Coordinate | chr7:133484928-133826826 | |
| Strand | - | |
| Gene summary | This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein that localizes to the cell surface. About a third of the mice lacking the encoded protein die before weaning. Overexpression of the encoded protein in a mouse model of Duchenne muscular dystrophy alleviates the muscle pathology by preventing cell necrosis and inflammation. [provided by RefSeq, May 2016] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| Adam12P1 | chr17:91855566-91859777 | + |
Intergenic |
ENSMUSG00000117629 | UCSC |
| >NM_007400.2 |
| GCCAGAgtagcgcgcgcgcgcacgcacacacacggggaggggagaaagtttttttttgaaaaaatgaaaGGCTAGACTCGCTGCTCAGCGACCCGGGCGCTGCGCGAGGGGGTCGCGGCAGACTCAGGGCAGTAGGACTTCCCCCAGCTCGGCGCCCGCGTGGGATGCTGCAGCGCTGGCCGCGGGGCCCCCGAAGCAGCTGCACGCCAGGCCGGCGACAATGGCAGAGCGCCCGGCGCGGCGCGCGCCCCCCGCCCGCGCCCTCCTGCTGGCCCTGGCTGGGGCCCTGCTGGCGCCCCGTGCAGCCCGAGGGATGAGTTTGTGGGACCAGAGAGGAACTTACGAAGTGGCCAGAGCCTCCCTTCTGAGCAAGGACCCTGGGATCCCAGGACAGAGCATCCCAGCCAAGGATCATCCAGACGTGCTGACTGTGCAACTGCAGCTGGAGAGCCGAGACCTGATCCTCAGCCTGGAAAGGAATGAGGGACTCATTGCCAATGGCTTCACGGAGACCCATTATCTGCAAGATGGTACTGATGTCTCTCTCACTCGAAATCACACGGATCATTGTTACTACCATGGACATGTGCAAGGAGATGCTGCATCAGTGGTCAGCCTCAGTACTTGCTCTGGTCTCCGGGGACTTatcatgtttgaaaataaaacgTACAGCTTAGAGCCAATGAAAAACACCACTGACAGCTACAAACTCGTCCCAGCTGAGAGCATGACGAACATCCAAGGGCTGTGTGGGTCACAGCATAACAAGTCCAACCTCACCATGGAAGATGTCTCCCCTGGAACCTCTCAAATGCGGGCAAGAAGGCATAAGAGAGAGACCCTTAAGATGACCAAGTACGTAGAGCTGGTTATTGTGGCAGACAACAGAGAGTTTCAGAGGCAAGGAAAAGACCTGGAGAAAGTTAAGCAGCGATTAATAGAGATCGCCAATCACGTTGACAAGTTTTACAGACCACTGAACATCCGGATCGTGCTGGTAGGAGTGGAAGTGTGGAATGACATCGACAAATGCTCTATAAGCCAGGACCCATTCACCAGCCTCCATGAGTTTCTAGACTGGAGAAAGATAAAGCTTCTACCTCGAAAATCCCACGACAATGCTCAGCTTATCAGTGGGGTTTATTTCCAAGGAACCACCATCGGCATGGCACCCATCATGAGCATGTGCACTGCAGAACAGTCTGGAGGAGTTGTCATGGACCATTCAGACAGCCCCCTTGGTGCCGCAGTGACCTTGGCACATGAGCTGGGCCACAACTTCGGGATGAACCATGACACACTGGAGAGGGGCTGCAGCTGCAGAATGGCCGCAGAGAAAGGAGGCTGCATCATGAACCCGTCCACGGGGTTCCCATTCCCCATGGTGTTCAGCAGCTGCAGCAGGAAGGACCTGGAGGCTAGCCTGGAGAAGGGCATGGGGATGTGCCTCTTCAACCTACCAGAGGTCAAGCAGGCCTTTGGGGGCCGGAAGTGTGGAAATGGCTatgtggaagagggagaagagtgtGACTGCGGAGAACCGGAGGAATGCACGAATCGCTGCTGTAACGCTACCACCTGTACTCTGAAGCCAGATGCTGTGTGCGCGCACGGGCAGTGCTGTGAAGACTGTCAGCTGAAGCCTCCAGGAACTGCATGCAGGGGCTCCAGCAACTCCTGTGACCTCCCAGAATTCTGCACAGGGACTGCCCCTCACTGTCCAGCCAATGTGTACCTACATGATGGCCACCCGTGTCAGGGCGTGGATGGTTACTGCTACAACGGCATCTGCCAGACCCATGAGCAGCAGTGTGTCACGCTCTGGGGACCAGGTGCTAAACCGGCTCCTGGCATCTGCTTTGAGCGAGTCAACTCTGCAGGAGATCCTTATGGTAACTGTGGCAAAGACTCCAAGAGCGCCTTCGCCAAATGTGAGCTGAGAGATGCCAAGTGTGGGAAAATCCAGTGTCAAGGTGGTGCAAGCCGACCTGTCATTGGTACCAATGCTGTTTCCATAGAAACAAATATCCCACAGCAGGAAGGAGGTCGGATTCTGTGCCGGGGGACCCATGTGTACTTGGGTGATGACATGCCAGACCCAGGGCTTGTGCTTGCAGGAACAAAGTGTGCAGAAGGAAAAATCTGCCTCAATCGTCGATGTCAGAATATCAGTGTCTTCGGCGTTCACAAGTGTGCCATGCAGTGCCACGGCCGAGGGGTATGTAACAACAGGAAGAATTGCCACTGTGAAGCCCACTGGGCTCCACCCTTCTGTGACAAGTTTGGCTTTGGAGGAAGCACAGACAGTGGTCCCATCAGGCAAGCAGATAACCAGGGCTTGACTGTAGGAATCCTGGTGAGCATCCTGTGTCTGCTTGCTGCTGGATTTGTGGTGTATCTCAAAAGGAAGACGTTGATGCGGCTGCTGTTCACACATAAAAAAACCACCATGGAAAAGCTAAGGTGTGTGCACCCTTCCCGGACACCCAGTGGCCCTCACCTTGGCCAGGCTCACCACACCCCCGGGAAAGGCCTGCTGATGAACCGGGCACCACATTTCAATACCCCCAAGGACAGGCACTCGCTGAAATGCCAGAACATGGACATCAGCAGGCCCCTCGACGCTCGAGCCGTCCCACAGCTTCAGTCACCTCAGCGAGTGCTCCTGCCTCTCCACCAGACCCCACGTGCACCCAGTGGCCCTGCCAGGCCCCTGCCCGCCAGTCCTGCAGTCAGGCAGGCCCAGGGCATTCGAAAACCCAGTCCTCCTCAGAAgcctctgcctgctgatccaCTGAGCAGGACTTCTCGGCTCACTAGTGCCTTGGTGAGGACCCCAGGGCAGCAGGAACCTGGGCACCGCCCAGCCCCCATCAGACCTGCCCCTAAGCATCAAGTACCCAGACCTTCCCACAATGCCTATATCAAGTGAGAAGCCAGCCCAGACCGGTCCTCAACAGTGAAGACAGAAGTTTGCACTATCTTCAGCTCCATTGGAGTTGTTGTTGTACCAACTTTCCGAGTTTCTAAAGTGTTTAAAACACCATTCTCTCCAGACCCTGGAGCCACTGCCATCGGTGCTGTGCTGTGGTGCTTTGTGTACTTGCTCAGGAACTTGTAAGTTATTAATTTATGCAGAGTGTCTATTACTGCGCAGGGCGCCGTAGCAGGCATTTGTACCATCACAGGGCTTTTCTACAGAAGGAAGGCTCCTCgtgcttttgtttttctggaggaCTTGAAATACCCTGCTTGATGGGACCTAAGATGAGATGTTTACTTTCTATTCAAGGCCTTATCGGAAAATAGCTCCCCACCTTCCCAAGGCTGTTATGGTACCAGACACACAGCTCAGGACACCCCAGGGAGAACCTGGcatgggttttctttgtttgctttcattttatcttttatattttggTATCCCTATCTTGGGTTGTAGCCAGGGCCTTCAGGAAGGTCTTGGGCCACTGCATGCTAATGGCCTTCAGGTCCTGCACCCTGAAGCTCTCAGACAACAAGTAGGATCTGCTTTCTAGCCAGCAGCTTTGGAGAGAACCTGGGGTACTGAAAAGAAGGTTTGGGGTGTGGTTATACCAGGATGGAGACTGGAATCCTAATCTGGGCAAACATCTGACCTTGAGCTGAGCAGCCATGAGCACCTCTAGGAAGCAAGGACGGCTGAGGTGCTGCACAAGGCTCTGCTTTGAGAGCTGGCAGGGGCTTCTCTCTGGCTGCCCTTTGCAGAGTGCTAGCTGGCATGGCATGTTGTTTACATCGGGAACAGTGGTGTTTCTACAAGAAAGCCACTGCCTGGGCACTGCAGACCTCCGTCTCCTGCCCATTTAGAGCTAAGCAAATTACCACATTGTCTTCTGGACTGTAATACAATGACCCTGTGTTCTGACAGATAGAGGAGGCTTTCTATGGAACCATAACTATTTTCAGATGTGAACTAGTAACCAGATCTAGTCGatcaactctggagatagaaatctccTTTTTACTGCAAGGCTCGACTTATTAAAAATTAGGCAGAATCCATATGCTTGCAAAAGCTATAACCACGTGGAATGCTCTTCTCATGGCACAGCCTGAGTCTGGTATCCTTATTAGTAGCCATTGGACAAAGCACCCAAAGTTACCTGTGTGTTCTCTTCAAGGCATCCTAATTTCTTCAGCATAGAGAGACTCGGTCTTCCTCACATTCTGAACATACCTATCAATGACTAAGACAGCAAGGCAATCCGTTTCCGAATACTGAGTTGCTCACGAAAGGCAACCTCAGCCAGGCAACTCTTTCCCTCTGCTCTTTCAGTATGTGACTGGGAAGCTACCTTCAGAAGCAAATCTTCAAGGTGCCTCAACCCAATGGCATgaaagatatatatttaaaaaataataatgtaatgcCAGAGGCCTTCCCTGCCTCCAGATGGGGCGTAGGATGACTAGCTTTCACGACAGAAGGTAAATGACAGCAGTCCTCTACCTCGTCTGACTGCTTTAAGATCAAGGCTTCTTTGGAAGGGTAACTAACATTAATGGCTGGCCTGTGCCTTGAAGCAGAAGGGAAAATACAGATAAGGAATTTGGTTTGCTTTCTAGAATCCAAAACTGTATCCAGCATTGGGAAGCATGGTCTTCATGACTGGGTAAATAAATCCACGTCACAGATGCATAAAAGAATAACTCTTATGACATGCCTCTTTTTGTGGCACAGAGACAATATTGCTGCCACTGAGATGCATACAAAATTTCTGTAACTGATATGTCATTCAGTAGTTGTATTAAGGCCAAACATCCACAACTGTAAAGACTTATAGAGTTGTGTGGGCGTTGTCTTGTGAGACACACAAAGCCTCAGCTGAAGCGTATGAGCTCCTCCTCCAGGTGGGAGTGATGGGGAGGCTAGAAACACACAAAGACAACAGAAGAGCTTTGGTTTGGGGGGGGTGCAGAGAGAGTGTGGTTTAGAGGAAGTTGGAGCCATGATCTTCTGCCATCTCCCCAGTGTCCACTAAGGATGCCGATGGTGCCTTACCAGCTGTGCAGTGCTGGCTGCTTGCTTTTACAGAGCCATGCATTCATTTCTGAATAAGAACATATTTAATCCTGAAATTCCCTTACAGGACAGACAGTGTTACTAAAGGAATTCCTCTAAGATACAGTAGTTGTCAATTAAAGCATATTTAGCAGTAACTTCAATTTTAACAAAATTGGGACCCAATAGCCAGCATGAGGGTTCTTTGACAGAGGGtagtttctctctccctttctccatccTTCAAATGACAAGACGTCAAAACTAATACAGTTCATTTGCAGTCCATCTCATGCTTATACATACTAGAGGTATGACTAAAGTTGGTTGAGTCATGGGAGACCATCCCTGAGAAAGTCCAGTCGGTCAAGAGCCTTGCCAGGTGGCGTGGCTGGACGTCCTCCTTTTGTTCCTGCACTGAGGAATAGTTATAGGTTATGTGACCCCACTTCACAGGCAAGTGGGAGGCGAACCTTGCAGGCATGCCCCTTAAAAGCTGGTCTCAGACCTACAATAGTCCTGAGTCTGTTTTCCCAGCACACAGAGAGCAACAATGCAGTTTTCCATTTCAAAATATGCATGCCGAGTTTGCGCTCTGTGTGAGTGTTTCCAGGTTACACATATGGGATGACATCACAGAAACCACACAAGCAACAAATTAAATTCTACGGGAAGAAATCCTCCTGACTGGTCTCTGAGGAGACATTTTTATGCCTTCTTAACTTTATTAGGAACTCTCAGGCTGAAGCTATGGGTCATTGTTCTCCAACAAATCAATACAAGCCATCAATGCACTCTCGAAGAACTGCCAAACCCTGATCTGTGTGAATGTTCTCAGGAGCCTGTGATCCCCATGGTGCTACAAAGAGGCTGGAGCTGGGCCAACAAGAAGGCCTaagagtcctcctgcctctcagcAGATGTTTACTGAGCACTCTGAGCCAGAAGCACCCCGACAACCAGGAGGACGATGGCTGGGCAGTAGGGCGCCCAGCCACTTGCAGCTCTTTCCTCTGAGGCCCGCTTTGTGTTTTAATTCCCTTCTGTCAGGCCCCAGCCAGAGGACACTGTCTATAGATCCTCCCTCTCAGTTTTCAGACGGCCTAAGCCATACACAAATGACCCAGACTAAGAAACACCAATACTCCCAGCAGTCCCAAGAACTGGTTTTTAAACACTATGACAAGTAGAAGAGGGTGTCACAgaggccattttttttcttttctttccactcATACTGGAACCTAGGTCCTCTCTCTACACTCCTAGTTCCTTTACACAACTCGGCAGTGGCTCCATTACACCAAGgacacagaaaaacacaggtaCCGATTTGCCTTCCTCTCCTGCCAATCACAAGTGCCTTACTCTGACCAGACCCATGACAAAACCTCTGTCATCCAAGAGAGCCAACTCTCTACCTTTGTTACTACTTCAAGCCAATGTGGTAACTGCTAACCTTCAAGGGTCACCTAAACAGTATAGTCCAACCTTCACCAGGACCATAGCACAGAGCAacctccagcacacacacacacacacaccttgaatctATCCCACAGCATATCAACCACAGTGACCTCCCTCCCACCGCCTTGTTCTAATTACAAGGTGAAGATGGCCATAGAAAATCAAGTTAGCACTAATTACAAAATGCTTTTGATGCAACCTGAATTTCCCAATGGCACCTATTGCTTTGAAACTCTGATGAGTTAAGTCATGCTCTGGGAGCTGTGAGCCCCATGCTCAGATCCACTGGGCAGGGGGGACTCCTTGCAGGAGACATGGGCACACATATGAATGTACCATTTCCATGCCTTTTGTGGAGTACagacatataaacataaatacttCCATTCACGCACACACGCTTACATTAGGAGTAGTAGTAAGTTTATTATCAAAACACTGCAAGCTTTTCTCCTATAAGAGAAACTAGGAAGGGAAAATGTTGAGTGTGGAATTCTTAGGATGCTCAGTATGGACAGAGATCACCAGGAGGCCCTAACACTCAGGAATCATTTTCAACCTGGGAAACGATTTGGCCCCTGCAAGTTGAAAGCCCCACCACCTGCCTACCTTTCTATATCATACATCATGTTCTGCGTGATCTGAAATTCTCCAAGAAAGTAACATTTTAGCCCTTAATTTAGCACATTGAAATTGAGATAGAGCCGATGTCACGTGGCTTTCCTTATAATCCGATCAGACGCTGGTTTATGCTCACTGGCCTGTGTGCTGCTATGTCAGAAGGCAGTGATCAGAAAGCACACAAATCTCATGAGACTAGAAACACAATTAACAGCCCTCCCGTCAGGGCAACTTGGTAGTGGTTGGGATAGCCAGTCATCTGAATATTTGTGGCAACCAACAGCACAACCCGAGCTGGCCACAGACTGCTTAGCTCTGTTCTGACTGATAGTACATCTCAGTTAACCGGCACAGCCTTTCTGCAGGGCTTCGTCTACGGAGAGCGCTTTGGTTAGCTTGTTTTCATGTTTGTATGTTACATGCTGTTATTTTTGTACGCATTTCTCATATGGGGGAATCTACAGGTAAACACAGCCTCCGAGTTCAGTAGAAAATGTCATTGTTAAGAGTATTATATCCAATAAACAGTAAACAGATAAA 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