Summary

Gene Name	UHRF2
Specie	Homo sapiens
Full Name	ubiquitin like with PHD and ring finger domains 2
Also known as	NIRF|RNF107|TDRD23|URF2
Coordinate	chr9:6413148-6507054
Strand	+
Gene summary	This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

Retrocopy(s) from UHRF2

Retroname	Coord	Strand	Genomic Region	ENSG
UHRF2P1	chrX:74105408-74108717	+	Intergenic	ENSG00000223650	UCSC

Expression

Transcript Sequences

>NM_152896.3

ATAAGTAAACACTCTGCGCGGCGCAGACATGGCCTCTTCCTATCTTTGAGGCGGTGTCTGCGGCAGCGCCTCAGAGTGGTTCCGGTCGTCTCTCCTCAAGTCGGCTAGTCGGGCGCGCGCGCTGAGAGTCGTCGCCGCCTGTCGGGCCCGGCGTCCGGTCGGTCCGGTGGGCGCGCTCGCCCGCCTGCCGCTGAGGGCCCGAGCCGCAGGGAAAgcggcgcgggccgggcggggcgcggcgcCCAGAGCTCAGGGGGAGACAAAGGGGACCGGTTCCTCTCTAGGCGCCAAGATGTGGATACAGGTTCGCACCATTGATGGCTCCAAGACGTGCACCATTGAGGACGTGTCTCGCAAAGCCACGATTGAGGAGCTGCGCGAGCGGGTGTGGGCGCTGTTCGACGTGCGGCCCGAATGCCAGCGCCTCTTCTACCGGGGCAAGCAGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTTGGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCTTGTAAAAGGACTAATGGAAATATAAAGCATAAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGTGTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGACCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGAGGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCTGAAGGAACATTAAATGACTGCAAGATAATATCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGATGGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGTGGTGGGAAACATGAACCCAACATGCAGCTTCTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAAGTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAAAAGAAAGCAAAGATGCCGTCAGCTAGTACTGAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACTATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTTCACAGACCCCATGTTGGTGGAATTCATGGTCGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGACCGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTAACAAACATGAACAGGGCATTGGCCCTAAACTGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAGCCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTGGTGAAATACTGGCCAGAGATTTCATCAAGCCATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGGACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCTAAAGGACAGTCAAAGAAGCAGCCCAGTGGAACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCATCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGGGATGAAGTGCTTTCACATCTTGTGGAAGGACCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTTTACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCTTGCCGGCATGATCTTGGCCAGAATTACATCATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAAGGACGATGATCTGCCTGCTTTCACTGTGTTGTTCATGGTGGCTTTTTGGACAATAAAGAATCTAAAATGGGTGGGGAGGGTGGAAGAAATGGTGGACTGTATCTCTCACGTTCTGAAGCAGCTAATCCTCTTTCCCACATAGCCATCATCTTGTGTGTGTAGTAAGAGGCCCATTTCTCAACTGTCTTTTAAATATCTAAAGGTAGTTCCTGTAACAACTAGTTTTAATGAGTAAAAAGTCAAAGCCTCAGCTCTAGTTGATATCCAAGTTATGATTTATTTTGCAACTACCTCAGGACAGAAAAGATTTATGGGGATTTTAAAAATCATTGAATAACTAGTTAAATGAAATTTTAGCTACACACTGCCTCCCAAATATTAGTTGTGCCTGGTTCTTGTAATTTGATTTTACAGAAAAGGAAATGACACTTGAGATCCTTGGAATGAACACAGCTTCTAAAGTGTGCATATACTTTTTTAACGTCTCTTCTTCCATTACAATGTGTGTTTTGCAAGGACAGGTTCATTTTTTTTAGCCCACTTTGTGAACTCCATTGTGCTTTTTTCTGGTGTTTTATGCAAGTTGACTACTAATGACTAATGAGAACAATAATGAATGCATTGTTGCTGCATTAGTGTAATGTGGTGTGGTTTTGCACTTAAAAGAGGTATTCATATGCTCTAGTTGTAAATGTTCATGAAAATCCACTTCTCTACTAGTCGAACTGCTTTTAGTGTCTCACCAGTGGTTTTACATCTGCAGAGTTTTGAGGGCTGTGCTGACCTTTGAGAGGATTTGAAATTGCTTCATATTGTGATCCTAAATTTTATATTCACTATATTCCCTAAAGTATACCTTAATAAATATTTTATGATCAGAAAAA