Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Gene Name Prdx6
Plot displaying the genomic locations of a parental gene (in chr1) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name peroxiredoxin 6
Also known as 1-Cys Prx|1-cysPrx|9430088D19Rik|Aop2|Brp-12|CP-3|GPx|LPCAT-5|Ltw-4|Ltw4|Lvtw-4|NSGPx|ORF06|Prdx5|aiPLA2
Coordinate chr1:161067682-161078780
Strand -
Gene summary This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Dec 2014]

Retrocopy(s) from Prdx6

Retroname Coord Strand Genomic Region ENSG
Prdx6P2 chr4:25307776-25308233 + Intergenic
 ENSMUSG00000083737 UCSC
Prdx6P1 chr2:80123140-80124555 + Intergenic
 ENSMUSG00000050114 UCSC

Expression

Transcript Sequences

>NM_007453.4
ACTCGGCCAGCACTGATCTAGGTCTCCGCAGGAGCCCGCCCGCTGCTCACTGCTGCGGCTGCGCCTCCTTGTTCTCAGCGTCACCACTGCCGCCATGCCCGGAGGGTTGCTTCTCGGGGACGAAGCCCCCAACTTTGAGGCCAATACCACCATCGGCCGCATCCGCTTCCACGATTTCCTGGGAGATTCATGGGGCATTCTCTTTTCCCACCCACGGGACTTTACCccagtgtgcaccacagaacttGGCAGAGCTGCAAAGCTGGCGCCAGAGTTTGCCAAGAGGAATGTTAAGTTGATTGCTCTTTCAATAGACAGTGTTGAGGATCATCTTGCCTGGAGCAAGGACATCAATGCTTACAATGGTGAAACACCCACGGAAAAGTTGCCATTTCCCATCATTGATGATAAGGGCAGGGACCTTGCCATCCTTTTGGGCATGTTGGATCCAGTCGAGAAGGACGCTAACAACATGCCTGTGACGGCCCGTGTGGTGTTCATTTTTGGCCCTGACAAGAAACTGAAGCTGTCTATCCTCTACCCTGCCACCACGGGCAGGAACTTTGATGAGATTCTCAGAGTGGTTGACTCTCTCCAGCTGACAGGCACAAAGCCGGTTGCCACCCCAGTTGACTGGAAGAAGGGAGAGAGCGTGATGGTAGTTCCCACCCTCTCCGAAGAGGAAGCCAAACAATGTTTCCCTAAAGGAGTCTTCACCAAAGAGCTCCCGTCTGGCAAAAAATACCTCCGTTATACACCCCAGCCTTAAGTCTTTGCGGAAATTGGGGCTGCATCTGCACATCCAGTACTGGGGCCTGAGGATGTCAGCTGGCAGCCGTGGGTCCTTGCAGCAGGTCCGTAGAAAGATCGTGGCATGATCACAGCCGGTCCTGTAGATCGCTCGCTATACTACTGGGTCATTAAATGGAAATGGCACCAAAACCTTCTCGGGATTCTTTACTCTGTGCCTTCGCCAGCATTCTGCCCCTCTGCCTGTCACAGTGCCCTACTGACTGGCTCTCTTTGAAACGAATTATGTATTGAAGATTCCTTAGGTCTCTGTAGGGTCTTTGATCAGCAAACAAGGTAGTGTCAGTGTGGGCTCTGTGCTAGAATGATGAAACACCTTTTGTATCTTTCCGAACTGAATCTTCTGTTACCCATTTTGGAGAGCACTGACATAGGGAGAAGCTTTCGATTCTGTATTTTTAGTAAATAAAAAGTGGGGACAGCCGGGAGAATTCTTACAGGGAATCTATTGTAAGTTTCTATCGAAGTGGGCTCAGAAAGCCTTTCGCCTCCCAAGAGTGCGCATGTACCTCCTAGAGTTTCCACATCTGCTCTCTGGTGATGTCTGCCTGTGAACGCACCTTATAAAAGACGGGCGGTGACAGTGTTTTACCACTCAGTGTCCTAGTAGTGGGTGGCCATTTCTGAATTCTGCTTTTTGAGGTTCAACAAATAAAATCCTGATCAGAAAACCGTTGTCATGTTTTAAAGTACTACTATCTTAGACTCTAGCATGTCTATTGCACAGGCATGCTTCCTTCTTGCTGGGAATAGCATGGGTATGTTTCTCCAACAACATGAGTCTCCGCATGAACTGGAAGCCACTGAAGGATGAATTCCTACATGTATGTTAGGCtaattccttggttcctgttctCCTAAGTCTTGTGAACAGGTGTGCACCTTCTCagaggttctcaacttgtggCTCATAACCTCTTTGGTCACCAAGGACCAAtggaaaatatttacattacagttcataacgaTAGCGAATTTACAGTtaggaagcagaaacaaaaataattttatgtttaggGGTCAccgcaacattaggaaggttgagaaccactaatgGTTAGGTAGTCTGGCCTCATTAGTGTAAGCTCTGAGATAGtggtatattttgtttttctactcTGAACTGAATGGTTTCATTCCAACTTAGATACAGTGCTACTAGTCCAAGTCATTGTGAGTCTTAGTCTAGGTTGTAACAAAGATGCCTGGCTTGAGCATGGGATGTTTATTTCTAGGTGTCAAGCTGGAGAGTTAAATTCAAGGCAGTGGTGGGTCCTAGGTCATCCTCCTCCTAGGAGGCACCTCACTGCTTGCTCTTTTCCATTACACACGTAATTACTTTGGTCCCTGCTTTTAATGGGAAGTCTGGCTTCCAGTTCCTGTTGAGGCGTTTctggtttttgtgtgtttatgataCTGGCTTGTtttgtatgtagcccaggctagacctgAAATCTTTCCTGCTGCCACAGCTCCCCAGGGGCTCAGATTACAAATGTTACCATCATGCCCTATGCCATCAGCTTTGATGACAAAAGTTCAAAATCTAAACTGCCATTGTTGATCAT