Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Apex1
Plot displaying the genomic locations of a parental gene (in chr14) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name apurinic/apyrimidinic endonuclease 1
Also known as APE|Apex|HAP1|Ref-1
Coordinate chr14:51162406-51164645
Strand +
Gene summary Predicted to enable several functions, including DNA binding activity; NF-kappaB binding activity; and nuclease activity. Acts upstream of or within cell redox homeostasis. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; autopod; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Apex1

Retroname Coord Strand Genomic Region ENSG
Apex1P1 chr1:45558768-45559895 - Intergenic
 ENSMUSG00000100361 UCSC
Apex1P2 chr2:39448174-39448698 - Intergenic
 ENSMUSG00000084285 UCSC

Expression

Transcript Sequences

>NM_009687.2
CACGTGACCACACCAATCGCCCACGTGGGAACAGGCAGACTCCATTCTTTGTGCCGTGAGGGTCTCTGGCTTCGTTGGGAGGCAGCGCAGTAAACACTGCTTCGGTGCTCCAGGAGCCTAAGGGCTTTCGTCACAGCGATGCCAAAGCGGGGAAAGAAAGCGGCGGCCGACGACGGGGAAGAACCCAAGTCGGAGCCAGAGACCAAGAAGAGTAAGGGGGCAGCAAAGAAAACCGAGAAGGAGGCCGCGGGAGAGGGCCCTGTCCTGTACGAGGACCCTCCAGATCAGAAAACCTCACCCAGTGGCAAATCTGCCACACTCAAGATATGCTCCTGGAATGTGGATGGGCTTCGAGCCTGGATTAAAAAGAAAGGTTTGGATtgggtaaaggaagaAGCACCAGATATCTTGTGCCTCCAAGAGACCAAGTGCTCGGAGAACAAACTCCCGGCTGAACTGCAAGAGCTGCCTGGACTCACCCATCAGTACTGGTCAGCTCCGTCAGACAAAGAAGGATACAGTGGTGTGGGCCTACTTTCCCGCCAGTGCCCGCTAAAAGTCTCTTATGGCATTGgcgAGGAAGAACATGATCAAGAAGGCCGGGTGATTGTGGCTGAATTTGAGTCCTTTGTCCTGGTAACAGCCTATGTTCCCAATGCAGGCAGGGGTCTGGTAAGACTGGAATACCGACAGCGTTGGGATGAAGCCTTCCGAAAGTTTCTAAAGGACTTGGCTTCCAGAAAGCCTCTTGTGCTATGTGGGGATCTCAATGTGGCTCATGAAGAAATTGACCTCCGTAAccccaaaggaaacaaaaagaatgctgGCTTTACTCCCCAGGAGCGCCAAGGTTTTGGGGAACTGCTACAAGCTGTACCATTGGCTGACAGCTTCCGGCATCTCTACCCCAACACTGCTTACGCTTACACTTTCTGGACTTACATGATGAATGCCCGCTCTAAGAATGTTGGTTGGCGCCTTGATTACTTTTTGCTTTCCCACTCTCTTTTACCTGCATTGTGTGACAGCAAGATCCGGTCCAAGGCTCTTGGCAGTGACCACTGTCCCATCACCCTTTACCTAGCACTGTGATACCCTCCTGCAGTAGCTTCCTGCCTGGGAGATGGCTCTCTCTGCAGAAGTCTGGTGTTTTAGCCTTCAGGTGTTTGGTTTTGTATGTGCTCCCTCATTTTAAACATTAAACCAAACTTCTGGTTTCCTTTAGACAATCCAAGAGAAATAAAAGGCCCTACTTTCAGCTTGGCTTTCTTTGTCCCTTTGTGAAAACTACATATTCCCTTTTTCAT