Summary

Gene Name	Phb2
Specie	Mus musculus
Full Name	prohibitin 2
Also known as	BAP|Bap37|Bcap37|REA
Coordinate	chr6:124689252-124693908
Strand	+
Gene summary	Enables sphingolipid binding activity. Involved in several processes, including CD40 signaling pathway; regulation of gene expression; and regulation of phosphate metabolic process. Acts upstream of or within several processes, including mammary gland development; negative regulation of intracellular estrogen receptor signaling pathway; and negative regulation of mammary gland epithelial cell proliferation. Located in cell surface; mitochondrial inner membrane; and nucleus. Part of inner mitochondrial membrane protein complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Phb2

Retroname	Coord	Strand	Genomic Region	ENSG
Phb2P1	chrX:70771137-70771768	+	Intergenic	ENSMUSG00000082337	UCSC

Expression

Transcript Sequences

>NM_007531.2

GCACTTCCGGTGCCCTTTCTCCCGCGAGCTCTAAGGCCGCCGATCCTCGTGTGCAAGGCGAGGTCTGTAAGCTGGAGCGGGGCAGAGGCTGGCGGGCACCCCCTCCTGACCGCtggtgccgccgccgccgccttcgGGAGGATCAGACATGGCCCAGAACTTGAAGGACTTAGCTGGACGCCTGCCCGCCGGGCCTCGGGGCATGGGCACGGCGCTGAAGCTGCTGCTGGGGGCCGGGGCGGTGGCCTACGGCGTCCGCGAATCCGTGTTCACCGTGGAAGGCGGTCATAGAGCCATCTTTTTTAATCGTATTGGTGGCGTGCAGCAGGACACGATCCTGGCCGAAGGCCTTCACTTCAGGATCCCCTGGTTCCAGTACCCCATCATCTATGACATTCGGGCCAGACCTCGAAAAATCTCCTCCCCCACAGGCTCCAAAGACCTGCAGATGGTGAACATCTCCCTGCGTGTGCTGTCCCGACCCAATGCCCAGGAGCTCCCCAGCATGTACCAGCGTCTAGGGCTGGACTATGAGGAGCGAGTGCTGCCGTCCATTGTTAATGAGGTGCTCAAGAGTGTGGTGGCCAAGTTCAATGCCTCGCAGCTGATCACCCAGCGGGCTCAGGTGTCCCTGTTGATCCGAAGAGAGCTGACAGAGCGCGCCAAGGACTTCAGCCTCATCCTGGATGATGTAGCTATCACAGAGCTGAGCTTCAGCCGAGAGTACACAGCTGCTGTAGAAGCCAAGCAAGTGGCCCAGCAGGAAGCCCAGCGGGCCCAGTTTTTGGTGGAGAAAGCGAAGCAGGAACAGCGACAGAAGATTGTGCAGGCTGAGGGGGAGGCGGAGGCTGCCAAGATGCTTGGAGAAGCACTGAGCAAGAATCCTGGCTATATCAAGCTCCGAAAGATCCGGGCCGCCCAGAACATCTCTAAAACGATCGCCACATCACAGAACCGAATCTATCTCACAGCTGACAACCTTGTGCTGAATCTACAGGATGAAAGTTTTACTCGGGGAAGTGACAGCCTCATTAAGGGTAAGAAATGAGTGTGGACATCAAGAACCCCACCACCAGAGAAGTTGGCACACTTGTCCAGCTTGGAGGAGCCAGCTCGGGGGTCAAGCACAGCCCACCCTGCCCCAGGCATCATGTGATGGACTTTTCTGTATCTGCCCTCTTGGATTAAGGAAGACTGAGACCAGCCCTTTCAGAggctttcctccttcctgtgtTGGCTGGGAAGCGGGGTGGGACAATGTGATTTCTCCGTGATTTCCTACAGCCTTGAGCCTCTCCCAGAGTGGGGGAGATAACCACCATGCCAggaattctcaataaaatttttattacttaAAGCC