Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Calr
Plot displaying the genomic locations of a parental gene (in chr8) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name calreticulin
Also known as CRT|Calregulin
Coordinate chr8:85568717-85573560
Strand -
Gene summary Enables calcium ion binding activity; carbohydrate binding activity; and mRNA binding activity. Involved in several processes, including cellular senescence; peptide antigen assembly with MHC class I protein complex; and protein stabilization. Acts upstream of or within cortical actin cytoskeleton organization; positive regulation of NIK/NF-kappaB signaling; and regulation of meiotic nuclear division. Located in endoplasmic reticulum; external side of plasma membrane; and extracellular space. Part of MHC class I peptide loading complex. Is expressed in several structures, including central nervous system; extraembryonic component; gut; placenta; and spleen. Used to study congestive heart failure. Human ortholog(s) of this gene implicated in essential thrombocythemia; myelofibrosis; pancreatic ductal adenocarcinoma; sideroblastic anemia; and thrombocytosis. Orthologous to human CALR (calreticulin). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Calr

Retroname Coord Strand Genomic Region ENSG
CalrP1 chr2:140797227-140798169 - Intragenic
 ENSMUSG00000081731 UCSC

Expression

Transcript Sequences

>NM_007591.3
GGCTGTGTCAGGTTCGGGTGAGAGGTAGGTGAATATAAATTGAAGCGGCGGTGGCCGCGTCCGTCAATACCGCAGAGCCGCTGCCTGAAGATCGTCTTAAAAGGCCTGTGTGCCGCCGCCCCCTCGGCCCGCCATGCTCCTTTCGGTGCCGCTCCTGCTTGGCCTCCTCGGCCTGGCCGCCGCAGACCCTGCCATCTATTTCAAAGAGCAGTTCTTGGACGGAGATGCCTGGACCAACCGCTGGGTCGAATCCAAACATAAGTCCGATTTTGGCAAATTTGTCCTCAGTTCTGGCAAATTTTACGGGGACCTGGAGAAGGATAAAGGGCTGCAGACAAGCCAAGATGCCCGATTTTACGCACTGTCCGCCAAATTCGAACCCTTCAGCAATAAGGGCCAGACACTGGTGGTACAGTTCACGGTGAAGCATGAGCAGAATATCGACTGTGGGGGCGGCTACGTGAAGCTGTTTCCGAGTGGTTTGGACCAGAAGGACATGCATGGAGACTCAGAATATAACATCATGTTTGGTCCGGACATCTGCGGTCCTGGCACCAAGAAGGTTCATGTCATCTTTAACTACAAGGGCAAGAATGTGCTGATCAACAAGGATATCCGGTGTAAGGATGATGAAttcacacacctatacacactgATTGTGCGGCCAGACAACACCTATGAGGTGAAAATTGACAACAGCCAGGTGGAGTCAGGCTCCTTGGAGGATGATTGGGACTTTCTGCCACCCAAGAAGATAAAGGACCCTGATGCTGCCAAGCCGGAAGACTGGGATGAACGAGCCAAGATCGATGACCCCACAGATTCCAAGCCTGAGGACTGGGACAAGCCAGAGCACATCCCTGACCCTGATGCTAAGAAGCCTGAGGACTGGGATGAAGAGATGGATGGAGAGTGGGAACCACCAGTGATTCAAAATCCTGAATACAAGGGCGAGTGGAAACCACGTCAAATTGACAACCCAGATTACAAGGGTACCTGGATACACCCAGAAATTGACAACCCTGAATACTCCCCCGATGCAAATATCTATGCCTATGATAGTTTTGCTGTACTGGGCCTAGATCTCTGGCAGGTCAAGTCCGGGACAATCTTTGACAATTTCCTCATCACCAATGATGAGGCCTATGCAGAGGAGTTTGGCAATGAGACGTGGGGTGTTACCAAGGCTGCAGAGAAGCAGATGAAGGACAAGCAGGATGAGGAGCAGAGgcttaaggaagaagaagaggacaaGAAGcgtaaagaggaagaagaagctgaggataAAGAGGATGATGATGACAGAGATGAAGATGAGGACgaagaagatgagaaggaggaagatgaggaagaatcCCCTGGCCAAGCCAAGGATGAGCTGTAGAGGCCACACCACCTGCCTTCAGGGCTGGACTGAGGCCTGAACACCCTGCCGCAGAGCTGGCTGCTCCCAATAATGTCTCtatgagactcaagaacttttcATTTTTTCCAGGCAGGTTCAGATCTGGGGTAGATTCTGATTTTGTTCCCCTGCCTcccccattacccccccccctttttttttttactggtgtTTGTCTTTAATTCTCCTTCAGCCCTCATCTGGTTTCTCATTTTTGAATCAACatcttttccttctgtccctccctttctccatctTTTGGTCACTACCCTCCAACTCTAGGAACAGGGGTGTAGAGGAGAAGCCCTAGGCTTGAGATTTCATCTGCTCTCCTTCCTGCATCTCAGAGGAGGGCAGGAGAAGGGGGTGGTGTTTTCCCTCCCCCCGCACTGAGGAAGAATGGGGCTCTTCTCATCCCCTTTCTCCCTTGCCCCCAGGACTGGGCCACTTGTGGGGCAGCCAGTTCTAGCACAGCTCACACTGAGAGTGTAAGAACTACAAACAAAATTTCTATTAAATTAAGTTTTGTGTCTTCCCT