Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name CHMP4B
Plot displaying the genomic locations of a parental gene (in chr20) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name charged multivesicular body protein 4B
Also known as C20orf178|CHMP4A|CTPP3|CTRCT31|SNF7|SNF7-2|Shax1|VPS32B|Vps32-2|dJ553F4.4
Coordinate chr20:33811348-33854366
Strand +
Gene summary This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009]

Retrocopy(s) from CHMP4B

Retroname Coord Strand Genomic Region ENSG
CHMP4BP1 chr14:55298642-55299270 + Intragenic
 ENSG00000258469 UCSC

Expression

Transcript Sequences

>NM_176812.5
ggagaggcctgcggcggcagggagcggcgggactgggagcgggcgccggagccgacccgagccgagccgagccgagccgagccggagcgggcggcgaaggccggcgcggCGAGCAGCAACCATGTCGGTGTTCGGGAAGCTGTTCGGGGCTGGAGGGGGTAAGGCCGGCAAGGGCGGCCCGACCCCCCAGGAGGCCATCCAGCGGCTGCGGGACACGGAAGAGATGTTAAGCAAGAAACAGGAGTTCCTGGAGAAGAAAATCGAGCAGGAGCTGACGGCCGCCAAGAAGCACGGCACCAAAAACAAGCGCGCGGCCCTCCAGGCACTGAAGCGTAAGAAGAGGTATGAGAAGCAGCTGGCGCAGATCGACGGCACATTATCAACCATCGAGTTCCAGCGGGAGGCCCTGGAGAATGCCAACACCAACACCGAGGTGCTCAAGAACATGGGCTATGCCGCCAAGGCCATGAAGGCGGCCCATGACAACATGGACATCGATAAAGTTGATGAGTTAATGCAGGACATTGCTGACCAGCAAGAACTTGCAGAGGAGATTTCAACAGCAATTTCGAAACCTGTAGGGTTTGGAGAAGAGTTTGACGAGGATGAGCTCATGGCGGAATTAGAAGAACTAGAACAGGAGGAACTAGACAAGAATTTGCTGGAAATCAGTGGACCCGAAACAGTCCCTCTACCAAATGTTCCCTCTATAGCCCTACCATCAAAACCCGCCAAGAAGAAAGAAGAGGAGGACGACGACATGAAGGAATTGGAGAACTGGGCTGGATCCATGTAATGGGGTCCAGCGCTGGCTGGGCCCAGACAGACTGTGGTGGCCTGCGCAGCGAGCAGGCGTGTGCGTGTGTGGGGCAGGCAGGATGTGGTGCAGGCAGGTTCCATCGCTTTCGACTCTCACTCCAAAGCAGTAGGGCCGCGTTGCTGCTCACTCTCTGCATAGCATGGTCTGCACCTgggagatgggcggggggaggggggcgggcggggtgggaagtgCCTGCTGTTTATAATGTTGAATTTCTGTAAAATAAACTGTATTTGCAAATCCAACATTGAGCTTCTGGACTACGCTGACTCCACTGCTGAATCCTCAATGGAAAGGGTCGACTGGTTGCAGTTGAAATGACCTGAAATGTAGCCTCTGTCCTTGTAAGTCAGTTGACTTGCCGCACATCTCTTTGTGTACTTGTACGGTACTGGCAGAAAAGTCATTTTTCAAAAGCCATAGGCTTTTCCTTGCCCTTAGCTGTAATAATGCATCTGATTTTGATTTCCTCCAGAGCTGTGTTTCTGTCCATCACCTGTGTATTGGCCCTGTGTTTACCACTCTGGCCCACTCCTCACCCCCTTGCTCCCCTGGTCTTCTGGAGTTTGTGACATTGATTTGAAATGGATGGTGTTCTCTTGAGAGCAAGTGAGATTGTTAGAATTAAGTTCCAACTATACAGTTTTCTAACATAGCTATAAGGTCCTTGTTGCTGTTTGTGATAACTGATAGATAACTCATTGGAAACGTGCATACATTTATATTCAGATGAAATTATGGTTTGCACTGTCTATTAAATATCTCGATTAATTTTCATA