| Gene Name | Ctsb |
|
| Specie | Mus musculus | |
| Full Name | cathepsin B | |
| Also known as | CB | |
| Coordinate | chr14:63359911-63383372 | |
| Strand | + | |
| Gene summary | This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| CtsbP1 | chr2:55182075-55183897 | + |
Intergenic |
ENSMUSG00000082301 | UCSC |
| >NM_007798.3 |
| AGCGGAGGGCGGAGCTGCGCGGGTACTTAGGAGTGCACGGGAGAGGCCAGGAGCGGCTCCGTTTGGCTTGGTGGCTGCAGGCCCAGGCTGTCGCGCTGCGCTCGGTGAGTGCAGGATCCAGCATCCAGGATGTGGTGGTCCTTGATCCTTCTTTCTTGCCTGCTGGCACTGACCAGTGCCCATGACAAGCCTTCCTTCCACCCGCTGTCGGATGACCTGATTAACTATatcaacaaacagaatacaacATGGCAGGCTGGACGCAACTTCTACAATGTTGACATAAGCTATCTGAAGAAGCTGTGTGGCACTGTCCTGGGTGGACCCAAACTGCCAGGAAGGGTTGCGTTCGGTGAGGACATAGATCTACCTGAAACCTTTGATGCACGGGAACAATGGTCCAACTGCCCGACCATTGGACAGATTAGAGACCAGGGCTCCTGCGGCTCTTGTTGGGCATTTGGGGCAGTGGAAGCCATTTCTGACCGAACCTGCATTCACACCAATGGCCGAGTCAACGTGGAGGTGTCTGCTGAAGACCTGCTTACTTGCTGTGGTATCCAGTGTGGGGACGGCTGTAATGGTGGCTATCCCTCTGGAGCATGGAGCTTCTGGACAAAAAAAGGCCTGGTTTCAGGTGGAGTCTACAATTCTCATGTAGGCTGCTTACCATACACCATCCCTCCCTGCGAGCACCATGTCAATGGCTCCCGTCCCCCATGCACTGGAGAAGGAGATACTCCCAGGTGCAACAAGAGCTGTGAAGCTGGCTACTCCCCATCCTACAAAGAGGATAAGCACTTTGGGTACACTTCCTACAGCGTGTCTAACAGTGTGAAGGAGATCATGGCAGAAATCTACAAAAATGGCCCAGTGGAGGGTGCCTTCACTGTGTTTTCTGACTTCTTGACTTACAAATCAGGAGTATACAAGCATGAAGCCGGTGATATGATGGGTGGCCACGCCATCCGCATCCTGGGCTGGGGAGTAGAGAATGGAGTTCCCTACTGGCTGGCAGCCAACTCTTGGAACCTTGACTGGGGTGATAATGGCTTCTTTAAAATCCTCAGAGGAGAGAACCACTGTGGCATTGAATCAGAAATTGTGGCTGGAATCCCACGCACTGACCAGTACTGGGGAAGATTCTAATCTGCTTTGACTTCATTGTCCAGTCCTTAGGGGCTTTTTCCAAAATTTAGCGGCCCTGGCAGGGAATGAGGTAGACAGGGGAGTCTTTGATTCTTTGAGTTCATCTAACATGCATGAAGCTTTTGGCAAGATTTGGACGACTGGACCAGAGCTGCCTGCCATCAGAGCTACCCTCCAAACACTGTCCTTACCTGGCCTCCTCCTAGCCCATCCCACGACAGTGATCACAGTCTGCATCCTAGCCTCTCCCTAGACTAGTGCGGTTTGTAGTGCCTGCTGTTGTGGCTCTGCCTGCCatacctcccacccccatccccatcccagcATCCGAGGACCCAAGGGCTTTGACTGCAGGACTTCCAAAAGAACGAACACTTCACGAGAGGACAAATGCCACCTCTCAGCTGCATCTTGAAGCTGGTCACTTCTGGGTCTGTGGCAGGCATTCGTCAATGGCCCAGTGCAGTTCTCTGGAGAAAGCTACCTTTTCCCAAGGCATCTGCATCCATCGACATTGGTAATGTGGCCAGCTCTCCTTGGTCCTGTCCTCAGCCGATGCTTTTTCAATAGGATTTTTATGCTTTGTGTACCTCAACCAAGTATGAAGAGCTGTACTGGTTTTATAGATCACCCCCAATTGTATGGCTTAAAACAAGCTACATGGTCATGGTTTGCTGTGTGACCGACAGATAACCACAATGAAActagtctggaaaaaaaaacttgctttttGTTGTAGTTACCACTTAACCCTGTAGTTTAACAAGGAATGTCTGTGCCAATAAACCAATTCTCCCTCTGCTTGACATTGGCAGGGTGCACGGTTCTGTGCTGCAGTTTCAAGGCTTTTGTCTCTCCCCCTGGTTTCCTGTCACCCTCAGAAATGGTTCTCAAAACCGTACCTGTAACTGCTCACACCTCGGAGCACTTCCTCCTGCTTAGAGATAAGGGAGCTACACTTGTTTAATTAACCAAGGCgggcactcacatacatatgacCCGGACTGCCATCTTCTTAGAGGTCATTTCCCTGGAGTGGGGGCCAAAGCTTGCGCACCATGTTTAAGTTTTCTGGGTTACTGGATTTCATGGATTTTACAAAAATCATAGTGAAGTACAGTTCAAAGGGAACAGGGAGCCTCACTCATCAGCGTTGTCCTATGGATCTGTTACTTCCTGCTAAGTGAGAGGGAGGGGCTGGTTTCTCTGGAAGCCCGCCTTCCCATGTCGGCAATCAGAACTATATCAAAGAAGCTCTGGATGCCTGGCGAGTGCTAGAAGTGTAACTCGGTTTGAGGCAACCTGGCTTGGGTACTGGGGCTTTAGTACTGCAAGACAGTTCCACCGGTCTCAACTACACCCAATAGTTCCCTCCTACACTTCCTTTCTTGCCTCACCACATGCCCACCTGCAACTCCCTCCCTACCTCGCATAGCCAGTGAAGATGAGCTAAATTAAGAGAAGAGGACCCTGAACATCCTCTGATGGAGCCCAGGAAACCCGTTTTGTTATCGTATGCTTGGGGGTGGCTCTAGATGTCTTCCATAACCAGATTCTCCTGTGGGTGGTTTCCTGTGCTCAAGTCAAGAGCTGTCTTCCTTGGGTACATGAAATggatactcaggagacagaggcaagccgatctctgggagtttgaggccagactggtctacaataGACCTTGAAGCTAGGAGCATTTCCTTTTCAGCCTGCCCACAGGGCCTTTTGATGATTCTGTGTTTACACATCCCTACCTTTCTACACATTAGACTAGAACACGCCgttgtgtgttctttgtgtgGTCCTCAAACCTGAGCCAGTATGAGTGCCAGGCCTTTGAATAGTCGTTTGTAGCCCGACTAGGTCATTTCAGATAGATTTGGGCGATGGCCTTCAAACAGGGCCTATGACAGACAGCATTCATGCTGCCCAGGAACTCATTAGGTAACATGCCAGATCAACTTGGTCAGAAGTCTTGTTCCAGATCCATTAGAATACAGAACTAGCCTTAGCGCTCTCACTTCCACTACCACAGAGCCTGGGAAACTCAACAGCAGGGGGAACGCCTTCAAAGGGCTGTCCCAGACAGGATTTGCAAATAACCAGAGGAAGGTAGCAAGCACATCTTTCTAATAATTATGTCTGGATATGGGTGGGCCtctgagaaagcacacagatggTGTAAATTATATTGAGAGTCAAAAGCAGGCTAGGGATGTCTCCATGGTAGAGTGTTTGTCCAGCATATTGTCCAAGCAAGACCCTTGGTTCAGTGCCCAGCAACACAATAACAGGAGAAAGAGGTGTGTCATATGTAGACAGTATGTATAATGTCCGACTAAATGTATTTCTAGATAATGGCTTTATAGAAATGCACCATGCTAAATATCTGAATATAAAGAAAACTATCTGAAATTCAAGTGGAACTTGGGGTCTTATTTGCTAAGGGAAATAAGTTTCAGGGGGTTAGAGTCTGTCCCCCCTACCCCTTTATATTTATTCATGCAGTTTATGAGTactctgtcttcatgcacatcagaaggaatcagatctcattatagatggtagtgagccactatggggttgctgggaattgaacttaggacctctggaagaacactcaggtgctgagccatctctccagcctccaggtttTGATGTTAGAGACAGtgtcttatgtagtccaggccCACCTCCACAACTGAGGAGGATCTTAAAATCcaactcctcccttcctccctccctccctccacctcccacatgctgggattactggtAAGAGTTGTAGCTTCCAGAAAGGATGAACATTAAAACCTTCGGTTTCAGCGGGGTGGTATTTGTTCAAGGCTTAGAGCAAGTGACCAATGAAGTCTCCATGCCCCAGTAATCCAGCAAGGAATCTGTGCTTACAAAGTTGAATGGACCACTGAACTGGCCGAGGCACCTCAGTGATGAAGTCAACATACGCAGCAGGCTTAAGAGGGGAGCAGACTATGCTCTACATGTCTCTGTGGTCTGAGCGTACCCCAAAGGGTCATATACAGGTTCACAAAATGACAGGTAGCTGAGGCACTGTTCTCAAAAGGGCTCAATGCTAGTCTTCCAGAGTTAGGGCTCCAGAGACCAAGCTCTGTGGACAACAGTGGGGTGGCTCGTGCCTATAACTCGTacattcagaaggctgaggcagtggGATCACCATTAAATTCAAGGCTACATAGACTtgcaggccaacctgagctacagttACAGTGTACAAGTGTCAGCATGCCAGGGCGtcgactcctgcttcctgtcacgTGCTCTCTCCTGCATGTCCTCTCTCTACTGTAGTGTCATTTCTCACAAGGCCGTCCAAGGGCTAAAGATGGGGCCCCCCTCATCTTGTACTTTCATCCTCCTAAGCTGTTACATAAACAATCCTCTTTCCTTGGTAAAGCAGTTGGCCTCAGGTATCTTGTCCTACAGTCAGAGTGGTTGCCTAGAGCCTCTCCACCGCTCAAACACTGGTTTTCAGATACACAGGGTGTCAGAGGCCACCATGACAATGTAGCCAACTAACCACGCTGCAATTAAAAACCTACCAATATAGAA |