Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Eif2s1
Plot displaying the genomic locations of a parental gene (in chr12) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name eukaryotic translation initiation factor 2, subunit 1 alpha
Also known as 0910001O23Rik|2410026C18Rik|35kDa|Eif2a|eIF2alpha
Coordinate chr12:78908846-78933784
Strand +
Gene summary Predicted to enable ribosome binding activity and translation initiation factor activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of translational initiation in response to stress; and stress granule assembly. Acts upstream of or within protein autophosphorylation; regulation of translational initiation in response to stress; and translation. Located in cytoplasmic stress granule and nucleus. Is active in synapse. Is expressed in several structures, including brain ventricular layer; jaw; nose; orbito-sphenoid; and thymus primordium. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Eif2s1

Retroname Coord Strand Genomic Region ENSG
Eif2s1P1 chr1:83135733-83137150 + Intergenic
 ENSMUSG00000101173 UCSC
Eif2s1P4 chr11:77432889-77434306 + Intragenic
 ENSMUSG00000081451 UCSC
Eif2s1P5 chr15:44145266-44147577 + Intergenic
 ENSMUSG00000115730 UCSC
Eif2s1P3 chr2:66772905-66773801 + Intergenic
 ENSMUSG00000082218 UCSC
Eif2s1P2 chr2:108402830-108404276 + Intergenic
 ENSMUSG00000082113 UCSC

Expression

Transcript Sequences

>NM_026114.3
AGCGCACGCTGAGGAGCTTCGGCGTCCGGGGTTGGTGTTCCGAGTCTCCTCGTTGCCACTAAGCAGCACGGCGTGGGACCCTACTTCGGGATTCACACATCCACTTCAGAATGCCGGGGCTAAGTTGTAGATTTTATCAACACAAATTTCCTGAGGTGGAAGATGTAGTGATGGTGAATGTAAGATCCATTGCTGAAATGGGGGCCTATGTCAGCTTGTTGGAATATAATAACATTGAAGGCATGATTCTTCTTAGTGAATTATCCAGACGACGTATCCGTTCTATAAACAAACTGATCCGAATTGGCAGAAATGAATGTGTTGTTGTCAttagagtggataaagaaaaagGATATATAGATTTGTCAAAAAGAAGAGTTTCTCCAGAGGAAGCAATCAAATGTGAGGACAAATTCACAAAATCCAAAACTGTTTATAGCATTCTTCGCCATGTTGCTGAGGTATTAGAATATACCAAGGATGAGCAGCTGGAGAGCCTGTTCCAGAGGACTGCCTGGGTCTTCGATGACAAGTACAAGAGACCTGGATACGGTGCCTACGATGCTTTTAAGCATGCAGTCTCagACCCATCTATCTTGGATAGTTTAGATTTGAATGAAGATGAAAGAGAAGTACTCATTAATAATATCAATAGGCGTTTGACCCCACAAGCGGTCAAAATTCGAGCAGATATTGAAGTAGCTTGCTATGGTTATGAAGGCATTGATGCTGtaaaagaagccctgagggcaggTTTGAATTGTTCTACAGAAACCATGCCCATCAAGATTAATCTAATAGCTCCACCCAGGTATGTGATGACAACAACGACCCTGGAGAGGACAGAAGGCCTGTCTGTCCTCAATCAGGCTATGGCAGTTATCAAAGAGAAGATCGAGGAGAAGAGGGGCGTCTTCAATGTTCAGATGGAGCCCAAAGTGGTCACAGATACAGATGAGACTGAACTTGCAAGGCAGCTGGAACGGCTGGAGAGagaaaatgcagaagtggatggagATGATGATGCAGAAGAAATGGAAGCCAAAGCTGAAGATTAACGTTTTGGCAAACAGTCCAATTTAAGGAGTACGAAGCAGCCCTTCCTGGCTGTCAACCCTAGACTTGAGAGTTTTCCAGTATTGAAAACTTCAAagctgaatatttttatttccaagtaTTTAAGTATTCAACAAGCCAGAATCTAAATGCCCTCCTTCATGTCAGCTGTTTCCACATAGTGGCTCTAACACCTCAAGCATTTTTCAAGGGAGTGGCTTGATTTGACCAGAGACAAATCTTAAACAGCAGTCCTAATATTGGGCCTACAGTTTCCATTTCTCATGTCTCTGGAATGGCACCCTTATGGTTCAGAGATTTACCAGGGACTCCAAACACAAACAATCCCAATCTTTCTATATAAAATGTATTCAAGCAAACATCAAATAAATTTCTGGGATATTTAATTGTAGGCTTCTTCCTTCTTGTCACAAGTTAAAGCCAATCTGAATGCTCAGATCCTAATTATCTTCATATGGTAGAACTCAATGGGCAAGTAACTAAATGACTTATGCAGGAACAGACTCTCCAAAGGAATGTTAGAGAAGAAATTAGGAATTTGACCCCTGGTAGAGAAAAACCTTGAAATCAATTAAAGATTTATGTGCCTGTTAACTTACTTGAAAGCAGTGATAACTTGTGTGAGAAGTCATCACACTCAGTCCCTTTGGTTTATTCTAAGCTACTTACCTTGAATTCATAATTCAAGGGGTATTTTAATGTGCTGCTGCTTTGATGGAGTTATTTTGAGCAGCATCACCCATCTGAAGGGGACAGTTTCCTCTATCTGGTAGGTGCTACCTAATTCttgagttgtgtgtatgtgtgtgtgtgtgtgtatatatacatacatggttttatatatatataaaccacaCATGATGTGATTTAACAAAATTTTTAATCCCATTTTTACCTTCTCAAACTAGCTACTTTAAAGGTTAATGtgcaaaataattttttcaaataACACAAAGTTACAGCTACAATATCACATGTAGAAAGTCTTCATTTAGTTTGGCATGCTTATCTTAGGATATGTATactatttattatctgtaagcAAACTTGAAACTAAGTCAGTCCAGGACTAGACATCATGGGAAGAGTTCTAGAGTTGGGTACAGAAGCACATGCTGATGGCTCCAGTACTTGGAAAGTTGAGGAGGGAAAATTCCTTGAGCCAAGAGTTGCTGATCAGCCTGGACAACCACTGCAAGACTCTGTATCAAAAGGATTGGAAATTAGAATGTTGAGAGATGTTTTATGCCATTTATGAAAGTTCTTTTGTTTAATCTACTGGTCTAACCTTGTGTGACCCATTTCCGAGGAGCCATGCTTGCTAGTCTGCATACCATGTTGCTAGTATTTAGGGACTCTGAATGTACTCCAGATTGGCTgactacagcagtggttctcaaccttcctaatgctgggacctgTCGATACAGGTCTTCACATTgaggtgaccccccaaccataaagttatttttgttaccacttcataactttaattttgctactattatgaatcataatataaatatctggttTTTGATGGTCTAGAACAACCACTGGTCATGCATCAAGAAGCAAGTTTAGGGCCaggtatggtagtgcatgcctttagtcccatcaTAGACAgtggcagttggatctctgagttcaaggcataGCTGGTCTATATATACCAAGTTACAGGTCACCTAAGactgcatagtgagactgtctcaatttttttttcaagtttataaAAGAACATGAAGGTGTTACCAAAGCTGCAATAGTAACTGTAATCTCAGATAATTCAGAGACAGAATACACATATTTTAAGGATTTAGAAATATAGCTAAGTTGGCCTGGTGCATAGCTAGCAAGTCAAGGCCCTGGGATCAATCCCCATTACCACAGAAGAAAAAATGTATTATCAAGTATAGCAAGCGCCCTTTTCCTAGGGATTGTTTACTGAAAAGTTTTATATTTAAGAGAACAATTTAGTCAGGTTGGTGGCAtatatctttaattccagtacttgggaggctagCCTAGTTTTCAAAGCAAGTTCCAgcgctgttacacagagaaaccctgtctcc