Summary

Gene Name	Gnb1
Specie	Mus musculus
Full Name	guanine nucleotide binding protein (G protein), beta 1
Also known as	Gnb-1|Hg2a
Coordinate	chr4:155575757-155643726
Strand	+
Gene summary	Predicted to enable several functions, including GTPase binding activity; alkylglycerophosphoethanolamine phosphodiesterase activity; and spectrin binding activity. Acts upstream of or within several processes, including phospholipase C-activating G protein-coupled receptor signaling pathway; retina development in camera-type eye; and sensory perception of taste. Located in photoreceptor outer segment. Part of heterotrimeric G-protein complex. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; autosomal dominant non-syndromic intellectual disability 42; and myelodysplastic syndrome. Orthologous to human GNB1 (G protein subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Gnb1

Retroname	Coord	Strand	Genomic Region	ENSG
Gnb1P1	chr8:95486938-95487725	+	Intergenic	ENSMUSG00000110708	UCSC
Gnb1P2	chr14:96937209-96938044	-	Intergenic	ENSMUSG00000115315	UCSC

Expression

Transcript Sequences

>NM_001160016.1

GCAGGGGCCGCCGCGCCCATCCTGATGGCTGGAGGCGTCTGAGGGGCGGACGgcgacggcggcggcggcggcggcggtggcgggcGCGGGCGGCGAGGGCAGCGGGGCTGGGACTGGAACAGCCGCCGCGCGGACCCGACCAGCCTCGCCGACTCCTGCCCGCAGGCCGCGAGCGCGACGACCAGGCGGCGGCGTGGGCGCCAGACCGGGCGAGGGCGAGATAGACTTACATGTGTGGGAAACCAGACCAGAAACACTTCTGAGTCAAGAGCTTGGATTCTGAAGTGTGGAAAGCACTGAGACGTGAAGATGAGTGAACTTGACCAGCTGCGGCAGGAGGCCGAGCAACTGAAGAACCAAATTAGAGATGCTCGTAAAGCGTGTGCCGATGCGACTCTTTCTCAGatcacAAACAATATTGATCCAGTGGGAAGAATCCAAATGCGGACCAGGAGAACACTGAGGGGGCATCTGGCAAAGATTTATGCCATGCACTGGGGCACAGACTCAAGGCTCCTTGTCAGCGCCTCTCAGGATGGAAAACTCATCATCTGGGACAGTTATACCACAAACAAGGTTCATGCCATCCCTCTGCGCTCCTCTTGGGTCATGACCTGCGCATACGCTCCTTCTGGGAATTATGTGGCCTGTGGTGGCCTGGATAACATCTGCTCCATTTACAACCTGAAAACTCGTGAAGGGAATGTGCGTGTGAGTCGTGAGCTGGCGggacacacagGTTATCTGTCCTGTTGCCGGTTCCTGGATGACAATCAGATAGTTACCAGTTCTGGAGACACCACATGTGCCCTGTGGGACATCGAGACTGGCCAGCAGACAACCACATTTACTGGACACACTGGAGATGTCATGAGCCTGTCTCTTGCTCCTGACACCAGACTGTTTGTCTCTGGTGCTTGTGATGCTTCAGCCAAGCTCTGGGATGTCCGAGAAGGGATGTGCCGGCAGACCTTTACAGGACACGAGTCTGACATCAATGCCATATGTTTCTTTCCCAATGGCAATGCCTTTGCCACTGGCTCAGACGATGCCACATGCAGGCTGTTTGACCTCCGTGCAGACCAGGAGCTCATGACCTACTCCCATGACAACATTATCTGTGGTATCACATCTGTTTCCTTCTCCAAGAGTGGCCGCCTCCTCCTTGCTGGGTATGATGACTTCAACTGTAATGTCTGGGATGCACTCAAAGCTGACAGAGCAGGTGTCTTAGCTGGACACGACAACCGAGTCAGCTGCTTGGGGGTGACTGATGATGGCATGGCTGTGGCAACAGGGTCCTGGGACAGCTTCCTCAAGATCTGGAACTAAAGCCAGGAGcaggtGGATGGATGCCATGGCGACTGGAAGACCATTCCAACCTTGAATCGTTACAGCGATAGCATATCCTATCCAACCATACTAACGTGGACACCCACACCTCCCCTCAGAACTTCAAAAGGGCAAGATCTTTTTTCCTTCACTTATTGCTGAAACCAAGAGCACAATTCCCATTAAGAGAAGGATCTCTGTGCTGTAAACTAAACAAATTGTGCATTTTTTCTGGGGCCattgtttttggtttattttgttattttgttttgtttttgtttttttggtttcattttgttttgggttggtccaattttaaaaggaaatactacaataaaaatgtTAACCAGAAGGTAACCCTGAGTGTGATTGTGAGAGAGACACGCCTTTTTACTAGTTCATTTGCATTTAAATCAGTGATCCTGTTCTGTGGCATTCATGAAAAACAAGTTGAAGAATTTGTTTATCTGGAATTGTTTCTAAATATAAGTCATTTGTAGCAAGACTTTGGAAGCATTCTTTCTTAAACATATTCCTTTatgttcagtagttaagagaaccAGGGCCCACGGCGGTCTCTGACTTGTcactgatgttttttttttttttgtccctggcttgcttttttttttttttttttttttttttttgtctcatgtCACAGATGACTGTTTCGCACAAACACAGCATAGTGGAAGAAAAAATTTCAGAAGCAAAGTAGCCAAGCACATGTTAGGATGGCCACGAATGCTTGGTCAGAGTCCTTCCTTCCCTTGCTCAGCAGCGGACTTACTCCCAgcgccttccctccctcctgtccctcctgtCCCCTCACTGTCCACTTTCtgttctttccttgggtttcctGTGAAGTTGGAGGGACGTTTGTAGTCATGTGACACTAGCCGTCCTGCCCCTGCTgtcagagatttttttctccagagaGGTGCCTGTCCTGTGCTTGGATAGTCAGTTGGTTATTTGTGTATGAAACAATGTACAAATCAATGTTTTGAAAATAATGATCTCAGACTTTCTAAgttaaattttaaacaatttgaTTGTTTGCCATATTGGGTGGGGTTACTCTTAGAATCGCATGCTGTAGAAATGCTCTAAAGTGCATATAGGACTCAGTCCTtagatgttctttttattttaagaaataaccTCTTCAAGTTGTAACCGTGGCGGCTTTGTCCATTACTGTTGCTATTCTGCACACATATCGGAAGCAGCAAGCGCTTTACACACTTGAGTAGTGGGATAAGTCACTGTtttctttacaaaacaaaacagtcctgTTGGGAATGATTGCTGTTGGAttctggaagggaggggaaagctgCTCTGCTGCCTCTTTGCCACTTCCTGGAAGCCTTCCTCCCTGGAAGAACAGCCTTTTGCATCTGAGGCGACCATTTTTACACCATGCAGATCTTCGTGGTTATCATCTCAAAGCCATGTTCAGCAGCAGCGTTTGGACAGCAGTGTTCTGtgggccctcccctcccccatatccTGCACCCCCTCATAGCAGTAGTGGCTTCGCCATTCTGTTTTCTGCAGTGTCCTGTACAAAACTGTGCTGTGACTGTGCGGTAGGCCTGGACATGGCAAAGAGAATACAGCGAAGCCCCTTCTCTTCCTACCAAACAACTCTGTAGAGCTCTCTGCACCCTGTACCCTTTTCaccttttgtatttaattttaaagtcAGTGTACTGCAAGGAGGCTGGATGCAAGATAGATACTATATTAAACTGTACTGTTATTTAAGATGTAATAAAGCAGTTTGACATGAGGGA

>NM_008142.4

GCAGGGGCCGCCGCGCCCATCCTGATGGCTGGAGGCGTCTGAGGGGCGGACGgcgacggcggcggcggcggcggcggtggcgggcGCGGGCGGCGAGGGCAGCGGGGCTGGGACTGGAACAGCCGCCGCGCGGACCCGACCAGCCTCGCCGACTCCTGCCCGCAGGCCGCGAGCGCGACGACCAGGCGGCGGCGTGGGCGCCAGACCGGGCGAGGGCGAGATAGACTTACATGTGTGGGAAACCAGACCAGAAACACTTCTGAGTCAAGAGCTTGGATTCTGAAGTGTGGAAAGCACTGAGACGTGAAGATGAGTGAACTTGACCAGCTGCGGCAGGAGGCCGAGCAACTGAAGAACCAAATTAGAGATGCTCGTAAAGCGTGTGCCGATGCGACTCTTTCTCAGatcacAAACAATATTGATCCAGTGGGAAGAATCCAAATGCGGACCAGGAGAACACTGAGGGGGCATCTGGCAAAGATTTATGCCATGCACTGGGGCACAGACTCAAGGCTCCTTGTCAGCGCCTCTCAGGATGGAAAACTCATCATCTGGGACAGTTATACCACAAACAAGGTTCATGCCATCCCTCTGCGCTCCTCTTGGGTCATGACCTGCGCATACGCTCCTTCTGGGAATTATGTGGCCTGTGGTGGCCTGGATAACATCTGCTCCATTTACAACCTGAAAACTCGTGAAGGGAATGTGCGTGTGAGTCGTGAGCTGGCGggacacacagGTTATCTGTCCTGTTGCCGGTTCCTGGATGACAATCAGATAGTTACCAGTTCTGGAGACACCACATGTGCCCTGTGGGACATCGAGACTGGCCAGCAGACAACCACATTTACTGGACACACTGGAGATGTCATGAGCCTGTCTCTTGCTCCTGACACCAGACTGTTTGTCTCTGGTGCTTGTGATGCTTCAGCCAAGCTCTGGGATGTCCGAGAAGGGATGTGCCGGCAGACCTTTACAGGACACGAGTCTGACATCAATGCCATATGTTTCTTTCCCAATGGCAATGCCTTTGCCACTGGCTCAGACGATGCCACATGCAGGCTGTTTGACCTCCGTGCAGACCAGGAGCTCATGACCTACTCCCATGACAACATTATCTGTGGTATCACATCTGTTTCCTTCTCCAAGAGTGGCCGCCTCCTCCTTGCTGGGTATGATGACTTCAACTGTAATGTCTGGGATGCACTCAAAGCTGACAGAGCAGGTGTCTTAGCTGGACACGACAACCGAGTCAGCTGCTTGGGGGTGACTGATGATGGCATGGCTGTGGCAACAGGGTCCTGGGACAGCTTCCTCAAGATCTGGAACTAAAGCCAGGAGcagcaggtGGATGGATGCCATGGCGACTGGAAGACCATTCCAACCTTGAATCGTTACAGCGATAGCATATCCTATCCAACCATACTAACGTGGACACCCACACCTCCCCTCAGAACTTCAAAAGGGCAAGATCTTTTTTCCTTCACTTATTGCTGAAACCAAGAGCACAATTCCCATTAAGAGAAGGATCTCTGTGCTGTAAACTAAACAAATTGTGCATTTTTTCTGGGGCCattgtttttggtttattttgttattttgttttgtttttgtttttttggtttcattttgttttgggttggtccaattttaaaaggaaatactacaataaaaatgtTAACCAGAAGGTAACCCTGAGTGTGATTGTGAGAGAGACACGCCTTTTTACTAGTTCATTTGCATTTAAATCAGTGATCCTGTTCTGTGGCATTCATGAAAAACAAGTTGAAGAATTTGTTTATCTGGAATTGTTTCTAAATATAAGTCATTTGTAGCAAGACTTTGGAAGCATTCTTTCTTAAACATATTCCTTTatgttcagtagttaagagaaccAGGGCCCACGGCGGTCTCTGACTTGTcactgatgttttttttttttttgtccctggcttgcttttttttttttttttttttttttttttgtctcatgtCACAGATGACTGTTTCGCACAAACACAGCATAGTGGAAGAAAAAATTTCAGAAGCAAAGTAGCCAAGCACATGTTAGGATGGCCACGAATGCTTGGTCAGAGTCCTTCCTTCCCTTGCTCAGCAGCGGACTTACTCCCAgcgccttccctccctcctgtccctcctgtCCCCTCACTGTCCACTTTCtgttctttccttgggtttcctGTGAAGTTGGAGGGACGTTTGTAGTCATGTGACACTAGCCGTCCTGCCCCTGCTgtcagagatttttttctccagagaGGTGCCTGTCCTGTGCTTGGATAGTCAGTTGGTTATTTGTGTATGAAACAATGTACAAATCAATGTTTTGAAAATAATGATCTCAGACTTTCTAAgttaaattttaaacaatttgaTTGTTTGCCATATTGGGTGGGGTTACTCTTAGAATCGCATGCTGTAGAAATGCTCTAAAGTGCATATAGGACTCAGTCCTtagatgttctttttattttaagaaataaccTCTTCAAGTTGTAACCGTGGCGGCTTTGTCCATTACTGTTGCTATTCTGCACACATATCGGAAGCAGCAAGCGCTTTACACACTTGAGTAGTGGGATAAGTCACTGTtttctttacaaaacaaaacagtcctgTTGGGAATGATTGCTGTTGGAttctggaagggaggggaaagctgCTCTGCTGCCTCTTTGCCACTTCCTGGAAGCCTTCCTCCCTGGAAGAACAGCCTTTTGCATCTGAGGCGACCATTTTTACACCATGCAGATCTTCGTGGTTATCATCTCAAAGCCATGTTCAGCAGCAGCGTTTGGACAGCAGTGTTCTGtgggccctcccctcccccatatccTGCACCCCCTCATAGCAGTAGTGGCTTCGCCATTCTGTTTTCTGCAGTGTCCTGTACAAAACTGTGCTGTGACTGTGCGGTAGGCCTGGACATGGCAAAGAGAATACAGCGAAGCCCCTTCTCTTCCTACCAAACAACTCTGTAGAGCTCTCTGCACCCTGTACCCTTTTCaccttttgtatttaattttaaagtcAGTGTACTGCAAGGAGGCTGGATGCAAGATAGATACTATATTAAACTGTACTGTTATTTAAGATGTAATAAAGCAGTTTGACATGAGGGA