Summary

Gene Name	Klf4
Specie	Mus musculus
Full Name	Kruppel-like factor 4 (gut)
Also known as	EZF|Gklf|Zie
Coordinate	chr4:55527137-55536984
Strand	-
Gene summary	Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity; and beta-catenin binding activity. Involved in several processes, including canonical Wnt signaling pathway; positive regulation of core promoter binding activity; and transcription, DNA-templated. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of blastocyst development; and regulation of transcription, DNA-templated. Located in cytoplasm; euchromatin; and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and skin. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human KLF4 (Kruppel like factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Klf4

Retroname	Coord	Strand	Genomic Region	ENSG
Klf4P2	chr9:5951378-5952725	-	Intergenic	ENSMUSG00000110932	UCSC
Klf4P1	chr6:69866292-69867557	+	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>NM_010637.3

AGTTCCCCGGCCAAGAGAGCGAGCGCGGCTCCGGGCGCGCGGGGAGCAGAGGCGGTGGCGGGCGGCGGCGGCACCCGGAGCCGCCGAGtgcccctccccgcccctccaGCCCCCCACCCAGCAACCCGCCCGTGACCCGCGCCCATGGCCGCGCGCACCCGGCACAGTCCCCAGGACTCCGCACCCCGCGCCACCGCCCAGCTCGCAGTTCCGCGCCACCGCGGCCATTCTCACCTGGCGGCGCCGCCCGCCCACCGCCCGGACCACAGCCCCCGCGCCGCCGACAGCCACAGTGGCCGCGACAACGGTGGGGGACACTGCTGAGTCCAAGAGCGTGCAGCCTGGCCATCGGACCTACTTATCTGCCTTGCTGATTGTCTATTTTTATAAGAGTTTACAACTTTTCTAAGAatttttgtatacaaaggaacTTTTTTAAAGACATCGCCGGTTTATATTGAATCCAAAGAAGAAGGATCTCGGGCAATCTGGGGGTTTTGGTTTGAGGTTTTGTTTCTAAAGTTTTTAATCTTCGTTGACTTTGGGGCTCAGGTACCCCTCTCTCTTCTTCGGACTCCGGAGGACCTTCTGGGCCCCCACATTAATGAGGCAGCCACCTGGCGAGTCTGACATGGCTGTCAGCGACGCTCTGCTCCCGTCCTTCTCCACGTTCGCGTCCGGCCCGGCGGGAAGGGAGAAGACACTGCGTCCAGCAGGTGCCCCGACTAACCGTTGGCGTGAGGAACTCTCTCACATGAAGCGACTTCCCCCACTTCCCGGCCGCCCCTACGACCTGGCGGCGACGGTGGCCACAGACCTGGAGAGTGGCGGAGCTGGTGCAGCTTGCAGCAGTAACAACCCGGCCCTCCTAGCCCGGAGGGAGACCGAGGAGTTCAACGACCTCCTGGACCTAGACTTTATCCTTTCCAACTCGCTAACCCACCAGGAATCGGTGGCCGCCACCGTGACCACCTCGGCGTCAGCTTCATCCTCGTCTTCCCCGGCGAGCAGCGGCCCTGCCAGCGCGCCCTCCACCTGCAGCTTCAGCTATCCGATCCGGGCCGGGGGTGACCCGGGCGTGGCTGCCAGCAACACAGGTGGAGGGCTCCTCTACAGCCGAGAATCTGCGCCACCTCCCACGGCCCCCTTCAACCTGGCGGACATCAATGACGTGAGCCCCTCGGGCGGCTTCGTGGCTGAGCTCCTGCGGCCGGAGTTGGACCCAGTATACATTCCGCCACAGCAGCCTCAGCCGCCAGGTGGCGGGCTGATGGGCAAGTTTGTGCTGAAGGCGTCTCTGACCACCCCTGGCAGCGAGTACAGCAGCCCTTCGGTCATCAGTGTTAGCAAAGGAAGCCCAGACGGCAGCCACCCCGTGGTAGTGGCGCCCTACAGCGGTGGCCCGCCGCGCATGTGCCCCAAGATTAAGCAAGAGGCGGTCCCGTCCTGCACGGTCAGCCGGTCCCTAGAGGCCCATTTGAGCGCTGGACCCCAGCTCAGCAACGGCCACCGGCCCAACACACACGACTTCCCCCTGGGGCGGCAGCTCCCCACCAGGACTACCCCTACACTGAGTCCCGAGGAACTGCTGAACAGCAGGGACTGTCACCCTGGCCTGCCTCTTCCCCCAGGATTCCATCCCCATCCGGGGCCCAACTACCCTCCTTTCCTGCCAGACCAGATGCAGTCACAAGTCCCCTCTCTCCATTATCAAGagctcatgCCACCGGGTTCCTGCCTGCCAGAGGAGCCCAAGCCAAAGAGGGGAAGAAGGTCGTGGCCCCGGAAAAGAACAGCCACCCACACTTGTGACTATGCAGGCTGTGGCAAAACCTATACCAAGAGTTCTCATCTCAAGGCACACCTGCGAACTCACACAGGCGAGAAACCTTACCACTGTGACTGGGACGGCTGTGGGTGGAAATTCGCCCGCTCCGATGAACTGACCAGGCACTACCGCAAACACACAGGGCACCGGCCCTTTCAGTGCCAGAAGTGTGACAGGGCCTTTTCCAGGTCGGACCACCTTGCCTTACACATGAAGAGGCACTTTTAAATCCCACGTAGTGGATGTGACCCACACTGCCAGGAGAGAgagttcagtatttttttttctaacctttcaCACTGTCTTCCCACGAGGGGAGGAGCCCAGCTGGCAAGCGCTACAATCATGGTCAAGTTCCCAGCAAGTCAGCTTGTGAATGGATaatcaggagaaaggaagagttcaagagacaaaacagaaatactaaaaacaaacaaacaaaaaaacaaacaaaaaaaacaagaaaaaaaaatcacagaacagATGGGGTCTGATACTGGATGGATCTTCTATCATTCCAATACCAAATCCAACTTGAACATGCCCGGACTTACAAAATGCCAAGGGGTGACTGGAAGTTTGTGGATATCAGGGTATACACTAAATCAGTGAGCTTGGGGGGAGGGAAGACCAGGATTCCCTTGAATTGTGTTTCGATGATGCAATACACACGTAAAGATCACCTTGTATGCTCTTtgccttcttaaaaaaaaaaaaagccattattGTGTCGGAGGAAGAGGAAGCGATTCAGGTACAGAACATGTTCTAACAGCCTAAATGATGGTGCTTGGTGAGTCGTGGTTCTAAAGGTACCAAACGGGGGAGCCAAAGTTCTCCAACTGCTGCATACTTTTGACAAGGAAAATCTAGTTTTGTCTTCCGATCTACATTGATGACCTAAGCCAGGTAAATAAGCCTGGTTTATTTCTGTAACATTTTTATGCAGACAGTCTGTTATGCACTGTGGTTTCAGATGTGCAATAATTTGTACAATGGTTTATTCCCAAGTATGCCTTTAAGCAGAACAAATGTGTTTTTCTATATAGTTCCTTGCcttaataaatatgtaatataaatttaAGCAAACTTCTATTTTGTATATTTGTAAactacaaagtaaaaaaaaatgaacattttgtgGAGTTTGTATTTTGCATACTCAAGGTGAgaaataagttttaaataaaCCTATAATATTTTATCTGAACGAcaa