| Gene Name | Mdm4 |
|
| Specie | Mus musculus | |
| Full Name | transformed mouse 3T3 cell double minute 4 | |
| Also known as | 4933417N07Rik|Mdmx | |
| Coordinate | chr1:132913843-132958325 | |
| Strand | - | |
| Gene summary | This gene encodes a protein that has been shown to negatively regulate the activity of the tumor suppressor protein p53. Homozygous knockout mice exhibit embryonic lethality as a result of p53-dependent apoptosis and cell cycle arrest. Amplification of this gene or overexpression of the encoded protein has been linked to a range of human cancers. A pseudogene has been identified on the X chromosome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| Mdm4P1 | chrX:127162009-127166255 | + |
Intergenic |
ENSMUSG00000081739 | UCSC |
| >NM_001302803.1 |
| TCTATGGTTCCCCCGGCCTCCCCGGAAGCTCTTGCGAACGCTGGGTTTGAGAGGCCGGAAGTGGTGCTGCCGTTGCTCGCAGTTTCAAAATGCAGTGCAGGCCTTAGGGTCTCCGgctgccacccctcccccagctagGAGGGGGAGCGACTCATGGAGCGGCCGTAAGTTTGCTAACTGTGGAGTCTTCACTGCCAAAATGACATCACATTCCACCTCGGCCCAGTGTTCAGCATCTGACAGTGCTTGCAGAATTTCTTCGGAACAAATTAGTCAGGTGCGGCCAAAACTGCAGCTTTTGAAGATTTTGCATGCAGCAGGTGCGCAGGGGGAAGTATTCACCATGAAAGAGGTAATGCACTATCTAGGCCAGTATATAATGGTGAAGCAGCTCTATGATCAACAGGAGCAACATATGGTATACTGTGGTGGAGATCTTTTGGGAGATCTACTTGGATGTCAGAGCTTTTCTGTGAAAGATCCAAGCCCTCTCTATGACATGCTAAGAAAGAATCTTGTTACATCAGCTTCTATTAACACAGATGCTGCTCAGACTCTCGCTCTCGCACAGGATCACACTATGGATTTTCCAAGTCAAGACCGACTGAAGCACGGTGCAACAGAATACTCCAATCCCagaaaaagaactgaagaagaggaTACTCACACACTGCCTACCTCACGACATAAATGCAGAGACTCCAGAGCAGATGAAGACTTGATAGAACATTTATCTCAAGATGAGACATCTAGGCTTGACCTTGATTTTGAGGAGTGGGACGTTGCTGGCCTGCCTTGGTGGTTTCTAGGGAATTTGAGAAACAACTGTATTCCTAAAAGTAATGGCTCAACTGATTTACAGACAAATCAGGATATAGGTACTGCCATTGTTTCAGACACTACGGATGATTTGTGGTTTTTAAATGAGACCGTGTCAGAGCAATTAGGTGTTGGAATAAAAGTTGAAGCTGCTAATTCTGAGCAAACAAGTGAAGTAGGGAAAACAAGTAACAAGAAGACGGTGGAGGTGGGAAAGGATGATGATCTTGAGGACTCCAGGTCCTTGAGCGATGATACTGACGTGGAACTTACCTCTGAGGATGAGTGGCAGTGTACGGAATGCAAGAAGTTTAATTCTCCAAGCAAGAGGTACTGTTTTCGTTGCTGGGCCTTGAGAAAGGATTGGTATTCGGATTGTTCTAAATTAACTCATTCCCTATCTACATCTAATATTACTGCCATACCTGAAAAGAAGGACAATGAAGGAATTGATGTTCCCGATTGTAGGAGAACCATTTCAGCTCCTGTTGTTAGGCCTAAAGATGGATATTTAAAGGAGGAAAAGCCCAGGTTTGACCCTTGCAACTCAGTGGGATTTTTGGATTTGGCTCATAGTTCTGAAAGCCAGGAGATCATCTCAAGCGCGAGAGAACAAACAGATATTTTTTCTGAGCAGAAAGCTGAAACAGAAAGTATGGAAGATTTCCAGAATGTCTTGAAGCCGTGTAGCTTATGTGAAAAAAGGCCTCGGGATGGGAACATTATTCATGGGAAGACGAGCCATCTGACGACATGTTTCCACTGTGCCAGGAGACTGAAGAAGTCTGGGGCTTCGTGTCCTGCTTGTAAGAAAGAGATTCAGTTGGTTATTAAAGTTTTTATAGCATAGTTGAGTCAGTCACAGAGAAATACTAGGAGGACCAGGTCATTTATCAAAAAAATCAGTATTCttagaggcaggggcagaagaTCACCAATTTTGATGCCAGTCTGGGCCATATAATGAGATCTTAGTCTTAAAAGGATCAGTATTGAgcatcttttataaatgtgaccCATTGCATATGTTTATTTGTATAAGCATATATGAACTTTTAGCTAAGTTTTGAGGGTTTCATTAGTGAGAAGATACTTTGTTCTTCCAAATTGTGAACCCAGAGGGAATAATATCAATACAAACATAGCAATGCATTCTTTTATTCACTTCCAAATTATTGCAAGAATAATACATTAGTTGATTTATTCTCTACCCTGGTGTTATGTAATGTTCTTGAGGCATCAAAAtctaaagcatttattaaatactGGGGCTAACACTGAAGAGGACATATCCAGTCAGTCGCTCATtgtgtagtcaaggatgaccttaaattcctgatAGCTGTCTCTACCACCTATGTGCTCATAGGCTCATAGGCCGCCCCACTAGCCCATCTGAAATCTCTTAGTTTTAGGTCAGGTAACACAGGTGTACATCTCTCCACAGCCTTATTATCAGTTCCAAAAAGGAAAGGCACAGACTTTGTTGCCCACACTTTGCATTTGTCTCTCAAGCTGGctgggtgttttgtgttttgtgctcTGCAGCTGTTCACATTCTGAGGCAGTGGCCTATGATAAGGCTTGAACAGTAGAGAGGAGGAATGTAGCAGCTGTGAAAGGAGGGGAACAAATTGATCTCTTCAATTCTGCTTAGTCATTTTAGACCACATCAACTTAGTATAATATCAATATATGAACTGAAGATCTTCACGCTGAATCCCGTATGCCTGTTCTGTGTCCACTGAACACATGGCCATCTTGATGTTTCCCCAGGGACATGAGAACATCATTTTAAAGACCAAGTCCCTAGAACTATTGAGCTTGAGGGCAATCTAGCTGTCTTGGCTTTTCCTATGGCTCCTGCTGTTAGAAAGGGGGAGATGCATGGTATCCAGTCCCCTTAATGTCATTATGTCCCTGCTGGACTGGGACCACTGGGGCTCCTCTAATTACTACTAAGAGGAGCTATGTTAGCTTTATCTTGCATTGATCCCATGTTCCCTGTCTGTCCCATGCTCTACCATTAGACCCAACTTTACCAAATTCTCACTGGATCAGTTATCATAGTTACTCTTTAATTTTGATGACAAAGCACCaatgcaaaatataaaagaaagcatttaatggggTTTGCTTTTGAGAGGGTTAGAATCCATGATGGCAGGCAgggacagctgagagctcacatcttgatctgcaagtagaatgcagagaaaaagagagcccTGGAAAACCCCAGGGCCTGCCCCCCCAGTGTCGTAATTGGTCTACCTTTTCCACCGACTGGGGTCCAAGTATTCAAACTTAAGAGCCTGTGGTTTATATTCTCAtgtaaaccaccacattccatgaAAAGAATTACTAATTACTGTGCTGCAGAACCAGTATTAGGCGTTCTGGACACCTCTTCTATCAAAGAAATTACTTTTCACTCCAGGCTTAGGCAAATTCTTAGGACAAGGGTAgaaggcagccacattctttgtcAAACATAACCAGAATAAGTCTTTAGCCAGTTGTTAATAGTTGTTCTACCCTGCAGCCTCTTGATCTAGGCTTCCTCTCAGTACTAACTGTCTTTTAGGCTCCAACTGGACCCATTAAGCTCTGTTTACAGCCTTGAACCCTTTCTTAGTCCAAAGTCTTACACATTCCTccaaaaaaaccacatggtcaggtCTTTCACAGCAAAGATCCACTTCCTGGTAGTAGCTTCTGTGTCTTGGCTACTCTAaaattgctatgacaaaacatccCGACCAAGGCAGAATGTACAAGAAAGCATTgagtttatggtttcagaggtatTTAGTTCATGATAGAACagttgagagcttacatcttgatctgtaagtaggaggcagagagagaacccAGGGgatggcatggacttttgaaacctccaagcctTCACCTTGTGACAGACCTCCCCAACagagccacatctcctaatcctttccaagtaGTTcctccaactggggaccaaatactCCAGCATGAGCATAGGGGAGCATTCTCATTCACACCACCAGTTTGCCGAGGAACTTTCCTAGCCATGGCTTGTCATTCATTGCTCCCAGTTGATAATTTCACTATTTGTAGCAAACTCAGTGGCCAAGTCCTTGCTATTATGGGTCTTCTGCTTGTATTGAAAATACTGCAGCTCCTGTTGGGGTTGCTGTGCAGTCTCTCTGAGGGACTGATAACAGACTTGTATATCCATATCTCCATGGCAGTGAGAAACGGTAGCTTAGAGGTAATCCTAGAAGCCATCACTCACAGTCCCTGCTTGAGAATAGGCTATGATATGTCTAGCCCTGGACTTTAGTCATTTCCTAGACATGGACCTGCTGGGTGGAATTGGGTCATTATGATGTTTAATTCCAAGCACTGCATTCAAAATAGGATACATGATATAGTATGTCAGCTTCATTCTAACGTTTCTCCTAATCTTTTGGGGCAGAGTCTTGCTGTTTCACCATGACTGGCCTGGGCCTTACCCtacatctcaggctggcctcagctttGCAGTGACCTTCCTGCTtttgcctctcgagtgctggaatTCTAGGCATGTAATGACTAAAtttcttattttgctttttatttaagtttttgttACTCTATCTTGGACaaaaagtgcagagcagaggtgTCGGATTACTAGGAAAGTCTCCAGGGCTTCGCTGTTACTGTGTTCCCCACAGGGACTTCCTGGTTGTTGACGTGCTTCTGTTTACTACTGTGTCAGATGAGCGACTCAGAGCTCGGCTTCAGATAGGTGTGACTGCCGCCCTCGCCCATTTAGGATGTAGTAGATTTATGATTGAGGGCTGGAACGGGTAGATTACATTGTACCGCCAAGCATTTGTGACTGTGTGgatatatattcattatttatgtatatttaggTGTGTGTGATACTTTGCATGGTTTGAAAGAATCTATTCTGAAAGCCAGGATCATTTGTAACCTTTGTGTGTCAGTTCAATGTAATGTTGGGGCCTTTGAAAAGTTGATTGAGAAATTGGGGATCATTCCCAGTTCTCCGATGTTACTTGTTTAGTCCTCTTTAGAAAGAAAGACACTTTTGGACCAGCTGTTTcgctgttttgttctgtttccatgatattcTGTGAACCTCCATGGCTTTAGATACTGTGactgttattttcctttttgcCCAAATTGTTGATTCAGTCTAAAGAATACTATTTTTTGATGCCTCTTACaattcatgcatgtgcacactatAGATTGATGCTACCTTTGCTAAAAATGTCTTAAGATAAAGAACTAGCTCTTTAGAACCTGCACTTCAAAGATAAACCTGGAAGCTGTCCTGTGCCAAAAGTAAAGTGTACAATGTTTACAGATGGGTGGAATTTTGCACTGCCATAGGGAACGGTGAGCTCGCATCACGGGGTTCCTTAGATGTATGGGTAGATAGTTGCAGTTGAGCTTATGAGAGGAACTGTGGAGCCCTCTAAGGCTAAGCTGCTAATGAGTATCCAAGACAGGTGGTTGGTGAACGTGACTCCCTAGACCTAGCTGGGGTCTTCTGTTGACAGCTCTTCATGGTTTGCAGACACTATATGTTTTCTTTAGAGGAGCTGCCAGCTCTCCCCTCTTGTGAAAGACTGTCTTGTAGACATTTTGAGATCTTTTGATGTAATGTGCAATCCCAAGTAATGCCATTATTGGTGAATGTAGCATTGTTAAACTTTTATTGTAAATTATCTCTGATCTTACCTTGATAgccttagggttttttgtttttgtttttttttgttatgttttcagAGACAGAGTCTCGCTATTTGGTTTACCTAGAATTTGCTTTATGATTAGGCTGTCCCCAAACTCACAGATGTCTGCCTTTCTACCACCACGCCCATGTAACTGATGTTACCAAAAATGATCTCATATCCATGGTGTTGCTTATGTGTCTTTGCATAGGCGCCTCCTTCAGTCCCATCTAGGAGCACAGCACAGTAGAAGTCCATTTCTTAAGTGGGCAGAGTCAGAGATAAGCTAAGAGGGCAAGTAGTTGCTTCAGTGGTTTTTAGAGCTTGGCAAACGCTTTACTGAAGATTAGCATTGTGTTGTGACACTTGAGGGCCAATACGAGCATTTAATTTGTTACCTAAAGGTGCTTTGTGTTCTTAAACAGCAAGTATTTGATGTGTGTAAACATTTCCcttcattctccctccctcctcaccgtTTTTATGGTCTCCTATTTCTGAGTTAGCTGCATTTGGACATTGCTTTTATGCCAGAGGCCATCTGTCACCTTGGATGTTTAGaagtacagtgtacttatgtaggGTCCTCCTTGAGCCTGTCCTGAGCAGTGTTGTGGTTACAGAATTGCCTACGAGCTCCAACAGAGAGGTGGGGAAGCTGGGAGGGCACAGCTGTCTGGCTTCCTTTGTGGAGGTGTTGGTTTGTTTGAACACTAAGGAATTTGAGGTTaatcttccccctcttcctgccCATAGTTTTCACTTCCCTTTCAGTAAGAACGACCccctaaaagaaaacaggaggAGATGCAGCGCTTTAGGCCGCCTTAGCCAGCAGCTTGTGTCCTACTCTGGAAGTTGTAACCTACAGTTTTTCTCACCTGTAAAGCCAACACACACAGCTACCCGTTTCTACCTCAGTTTGATGTGGCGACTATGGAGGAACAACTCTTAAAAGCTCTGACTGCCTTGAAGATGGAGGAAGCTAGTGGTCTTGGTCGACTGTGCTCTGAGGTTTATATTGAGAATCCTTTATTCTGGAAGTGAGTGCGGTTCTCCTGACCGCCTGCTCAGTAGAACCTGTGTTGCCTGCTTTAAGTCTCTGCCCACCTGCCTGTCCTTTCCTTGACACTAGGCTCTTGATTAGGAAGAGTTGTCTCCAGATGCTTTGAGAAGCACATGTAAATCTAGATAGCACATTCTACCCTGATGGAACTTCCTTGCTTGTCTTGCTGTATAGGAATTCATTCTGTATACACTTGAGTGGGTGGCATGAGATGCTCGACTTGTGTGTCGAGAGGCAGTGTCATGACATTCCCAGTCTGGTACTTGCCAGTGCAGAAGCAAATGAGGGGTAATAAACTGAGAAGAAGGGCAGCTTACTAACGAGGCCAGAGGGAAATGTTTCCGTGTGTCCTTATGTAACTTTTTACAGTGCCACTAAGTTAATAGCCCTGTACATGGGTGTTTGCACTATGTAATGCTTTTAATGcggttttattgtgtttttgtgtGATTAAACAGTTTTCATTTCATTGTGTTTTGTCATTATTGGAAATAGGTAATTTTGCTTATGTACAGCTAACCCATTTTCTGTTATCTTTGGCATGATTTGGGGAAGTGATTAAAAGTCATTGGCAGCTTTTCCCT 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