| Gene Name | Nf2 |
|
| Specie | Mus musculus | |
| Full Name | neurofibromin 2 | |
| Also known as | merlin | |
| Coordinate | chr11:4715845-4799544 | |
| Strand | - | |
| Gene summary | Predicted to enable beta-catenin binding activity; integrin binding activity; and protein domain specific binding activity. Involved in lens fiber cell differentiation. Acts upstream of or within several processes, including negative regulation of MAPK cascade; negative regulation of protein kinase activity; and nervous system development. Located in several cellular components, including adherens junction; cleavage furrow; and ruffle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study familial meningioma; neurofibromatosis; otitis media; and renal cell carcinoma. Human ortholog(s) of this gene implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Orthologous to human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor). [provided by Alliance of Genome Resources, Apr 2022] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| Nf2P1 | chr18:8954362-8954679 | + |
Intergenic |
N/A | UCSC |
| >NM_001252250.1 |
| ATCACAGTATCTTAGAGAAAAAAGTGTTAGGGTGAGTCGCTGAGTAGCGTAGTGGGAGTCcggagggcggggcggggcggggatcCGGCAGGTCGCTGAGGTGGGGGTTGGTAGAGGACGCTTCCCGAGGGCGCGCGGAGCGGAGCTGGTGACAGACACGCACGCGCGTGTGCGCTCCCAACTACTGCGCGGCCCCGCGACCCTCGGGGGTCGCTGAGAGGCCCGGCGTCGGCGCCGCAGCCGTCTAGGATTTCTGTCCAAAGGCGTCCCTGGCGTCCCCAGCCCGAAGCTCCAAGCTCGGGGCTGCGCGTGCTTTTGCCGGCATCTCCCCCCGACCCCCCCGTCGTCAGAGACTGTCCCTTAACTCATCTTTCCGCACCCACAGCCGGGTCCTCGCGGCCCATGCTGGCCGCTGGGGACCCAGGCAGCCTAGGTCTGTCTCGGGCCGGCCAGCCGGCCACCATGGTGGCCCTGAGGCCTGTGCAGCTACTCCAGGGGGGCTAAGAGACCCAGAACGCGGGCCTAGGGGTGAGGGGATCCAAGGCCGGTACCTCGCGCCATGGCCGGAGCCATCGCTTCTCGCATGAGCTTCAGCTCACTCAAGAGGAAGCAGCCCAAGACATTCACGGTGCGGATCGTCACCATGGACGCCGAGATGGAGTTCAACTGCGAGATGAAATGGAAGGGGAAGGACCTGTTTGATTTGGTGTGCCGGACACTGGGGCTTCGGGAAACCTGGTTCTTTGGACTGCAGTATACAATCAAGGACACGGTGGCCTGGCTCAAAATGGACAAGAAGGTGTTGGATCATGATGTTTCGAAGGAAGAACCAGTTACCTTTCACTTCCTGGCCAAATTTTATCCTGAAAATGCTGAGGAGGAGCTAGTTCAAGAGATCACGCAACACTTATTTTTCTTACAGGTGAAGAAGCAGATTTTGGATGAAAAGGTCTACTGCCCTCCCGAGGCGTCCGTGCTCTTGGCGTCATATGCTGTCCAGGCCAAGtaTGGCGACTATGACCCCTCTGTGCACAAGCGGGGATTTTTAGCCCAAGAGGAATTGCTCCCGAAAAGGGTGATAAATCTCTATCAGATGACTCCGGAAATGTGGGAGGAGAGAATTACGGCTTGGTATGCGGAGCACCGGGGCAGAGCCAGGGATGAAGCTGAAATGGAGTATTTGAAGATAGCTCAGGACCTGGAGATGTATGGTGTGAACTACTTTACAATCCGGAATAAAAAGGGCACAGAGTTGCTGCTTGGAGTGGATGCTCTTGGGCTTCATATCTATGACCCTGAGAACAGGCTGACCCCCAAGATCTCCTTCCCATGGAATGAAATCCGAAACATCTCCTACAGCGACAAGGAGtttactATTAAACCACTGGATAAGAAAATTGATGTCTTCAAATTTAACTCCTCAAAGCTTCGTGTTAATAAGCTGATTCTTCAGCTATGTATTGGGAACCATGACCTATTTATGAGGCGACGGAAAGCTGACTCTTTAGAAGTTCAGCAGATGAAAGCCCAGGCCAGGGAAGAGAAGGCTAGAAAGCAGATGGAAAGGCAGCGGCTGGCTCGAGAGAAGCAGATGCGGGAGGAGGCCGAGCGTACAAGAGATGAGTTAGAGAGGAGGCTCCTGCAGATGAAAGAAGAAGCAACGATGGCCAATGAAGCTCTGATGCGCTCTGAGGAGACAGCTGATCTGTTGGCTGAAAAGGCTCAGATCACAGAGGAGGAGGCCAAGCTTTTGGCACAAAAGGCTGCAGAGGCTGAGCAAGAGATGCAGCGAATCAAGGCCACGGCCATTCGGACAGAGGAGGAGAAGCGCCTGATGGAGCAGAAGGTGCTGGAGGCTGAAGTGCTGGCATTGAAGATGGCTGAGGAGTCAGAGAGGAGGGCCAAGGAGGCTGATCAGTTAAAGCAAGACTTGCAAGAAGCCAGAGAAGCAGAGCGAAGAGCCAAGCAGAAGCTCTTAGAAATCGCCACCAAGCCCACCTATCCACCCATGAACCCAATTCCACCACCACTGCCTCCTGACATACCGAGCTTCGACATTATTGCTGACAGCTTGTCATTTGACTTCAAGGATACGGACATGAAGCGACTTTCCatggagatagagaaagaaaaAGTGGAGTACATGGAGAAGAGCAAGCACCTGCAGGAGCAGCTCAACGAGCTCAAGACGGAGATCGAGGCCTTGAAACTCAAAGAGCGGGAGACGGCCTTGGACGTCCTACACAGCGAGAGCTCAGACAGAGGCGGCCCCAGCAGCAAGCATAATACCATTAAAAAGCCTCAAGCCCAAGGCAGAAGACCTATCTGCATTTGAGTCCTCAAACTCACTCTGCAGAGCGCCAAGTCCCGAGTGGCCTTCTTTGAAGAACTCTAGCAGGTGACCCGGCCACCTCCTGCCACATCTGCTGCTCCTGACACCAACAGGATGGGCCTGACCCAAAAGGAACCATCAGTAGAGGGCTGGCTTGTTTGGGAACTCTTGAGTTGAGGGCCCCGTGCCACTCTGACCCTATAGAGAGGTTTCTCAATGTGTTCTAGTTCTCCTTGCCTCCTGCATACctgcatatctctctctccctccctctctctctctctccttctctctctctctctctctctctctctctctctctctctctctcttatataaaTACTTGTTGTGTGTGGGCTGCCATCCTTCCTGCACCCAAGCACTGTGGTGCACGGGTTGCTGTGCTTGCTGACATTGAGAATCGGCTGTGGGAGTCCAGTGTGAAAGCTGGCTGAAATCTACCATGCAGGTGCTACCCACTCCCCAACTGGGCTTCtgggatgggcctcccctccaAGCATGGGGTAGAAGTGTGGACTGGCTTAGCTCAGAACCAGCaatgggggttggggatttagctcagtgagaGCGCTTACTcgggccctgggttcggtcctcagctctggggggggaaaaaaaaagaaccagcaaCGATGGCTCCTTAGCCAGGCTCACCTGAGGCAGTGTAGCTGTCTGAATGGCAGGTAACAGGCAAGACAGCTGTGGCTAGGAAGAGGCTTAAGATAGAGGCTGTTGGGAGACACTGCACATGAGCCTTTGGTGGGCCAGGAGCTTCCCAGTCACATTCCCATCAGTGCCTGGGAACCCAGCTGTGACCAGGacctctgtctcctccccctcAGCACATGGAACCCCAGAGCCCTGCTACCCGTCCATCATCCTCTTCAACACCTAGGCCTCACTGTCATTGTCCTTTTCTTCCCCAGGAGCCCAGCAGTGTCCTTTTAGTCCTTCCTTTCCTGAGCCTGACAGAGATATCAGGCTACTAACAGTCACACAAGCTAACACTATGGGTTGCCTCCATGCTAGGCAACAAATGCTTACCATGTGCCTCACACACTCCATGATTGGGCCTATCTTCTATGTAACTGGGGTCACTAGTGTAGCCGACCAGAACCCTTTAAGTCCTACAGAGCAGGTGATCTGCCTCAGTCCACAAGCAGATGTATATTAACTGAGGACAGCTGAGCTGAGGGGCTGAGCAAGGCGATGTTCCACAGTacggtttgtttttgagaaactgaggcacaccaCCTTGTTCCCGGGCTGTTATTGGGCCACTTTGTCATAGGCAGCCACCCAATGGTCACCTCAGCATCTTTGGGCACCTGTGATAGCACTCTAGTCTGAAACCTAAGGCTGAGGAGAAGGTCTCTGGACTTGACACCCCAGTATTTGCCGAGTCTTCCCTGGCTGCTCTGAAGTTGAGCTGTGTTCTCTGGCCTGAAACTGCTCTCtgactttcttcctctctgtacACTTGATTTAACAATGGCTGTGGGACACGAGACAATGATGCTGGTTTATAAAAATTATGCCAGGCCTTCCTTGGCTTTTTCATTTAACTACGCTTTATATCTCAAATTTGGGAAATACCAAGCTACATAACCACGTGGGCGCCCTGGTATTTGAGGAATGGTGGGTGTAACCATTTCGCCATTTCTTGGAAGGTGAGGTCCAAACCCCACTCAGAAGTACCTCAgctccgagagagagagagagagagagagggggcgggggggagagagagagagagctcgaATGGGTCCCCAGAATGTCTCCAGCCTGCTTTGAGCCTGTAGCTGGGTTCTTACTGGTAGAAAATTTTAGTCAAAGAGAAACATCTGAAGTCCAAAGTGAGGCCCAACCCTGGCTCTTCCTAGTTTCAATGGTTTCTGAAGCATAGGCAGGGGTACCCTGCTACTGAAACAGCAAGTCACTCTCAGTGCAGGACACTGAGGCCTTGCTCTTGCCTGTGGCTGGTCACAAACCCTGATTGAGGCAGTACCTGAGCCGCCACAGCACTCTGACCTGAGGTCACTGCCAACCCCTGCTAGACAACACCAGTGGGCTTCACTTACTGCTATATCCTCTTTTAGACAGGTTTCTCATGCTCCCATACTTTCAAAAAGCCCAGAGGCTGACTCCCAGCAACAGTGACTAACCGTTCCTGCCAACAGGGCCAGAGCCTCAAAGTCCCTGGTACAAGCAGCCTTCACAGAGGACCCAGACTCTCCTAGGTGCCTTGAGGCCACGCCAGTGCCCATGGGCTTCCATTCCTCTGTTACTCTTTTCAAACAGCTCTTCATGTGAGGCTCCTGTCACTCCTATCGGGGCCAGGACATGAAGCTGGTTTCTGGGGGTTGGGGTGATTATAATTTAAGTGATTGTTTTAATAAAAACTCTAAGCTGCTATAGTC |