Summary

Gene Name	Vegfc
Specie	Mus musculus
Full Name	vascular endothelial growth factor C
Also known as	VEGF-C
Coordinate	chr8:54530567-54639489
Strand	+
Gene summary	Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of angiogenesis; and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of lymphangiogenesis; and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery; brain; cardiovascular system; embryo mesenchyme; and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Vegfc

Retroname	Coord	Strand	Genomic Region	ENSG
VegfcP1	chr13:26864527-26864677	-	Intergenic	ENSMUSG00000114225	UCSC

Expression

Transcript Sequences

>NM_009506.2

CCGCCACCGAGGGCAGTTCGGATGTCCGGTTTCCTGTGAGGCTCGTACCTGACACCCGGGAGCCTCTCCCCCGTGAGGGCTGCCAGAGCCGAGGGCAAAAGTTGCGAGCCGCCGAGTCCCGGGAGACGCTCGCCCAGGGGGGTCCCCGGGAGGAAACCACGGGACAGGGACCAGGAGAGGACCTCAGCCTCACGCCCCAGCCTGCGCCAGCCAACGGACCGGCCTCCCTGCTCCCGGTCCATCCACCATGCACTTGCTGTGCTTCTTGTCTCTGGCGTGTTCCCTGCTCGCCGCTGCGCTGATCCCCAGTCCGCGCGAGGCGCCCGCCACCGTCGCCGCCTTCGAGTCGGGACTGGGCTTCTCGGAAGCGGAGCCCGACGGGGGCGAGGTCAAGGCTTTTGAAGGCAAAGACCTGGAGGAGCAGTTGCGGTCTGTGTCCAGCGTAGATGAGCTGATGTCTGTCCTGTACCCAGACTACTGGAAAATGTACAAGTGCCAGCTGCGGAAAGGCGGCTGGCAGCAGCCCACCCTCAATACCAGGACAGGGGACAGTGTAAAATTTGCTGCTGCACATTATAACACAGAGATCCTGAAAAGTATTGATAATGAGTGGAGAAAGACTCAATGCATGCCACGTGAGGTGTGTATAGATGTGGGGAAGGAGTTTGGAGCAGCCACAAACACCTTCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGGGGTTGCTGCAACAGCGAGGGGCTGCAGTGCATGAACACCAGCACAGGTTACCTCAGCAAGACGTTGTTTGAAATTACAGTGCCTCTCTCACAAGGCCCCAAACCAGTCACAATCAGTTTTGCCAATCACACTTCCTGCCGGTGCATGTCTAAACTGGATGTTTACAGACAAGTTCATTCAATTATTAGACGTTCTCTGCCAGCAACATTACCACAGTGTCAGGCAGCTAACAAGACATGTCCAACAAACTATGTGTGGAATAACTACATGTGCCGATGCCTGGCTCAGCaggattttatcttttattcaaATGTTGAAGATGACTCAACCAATGGATTCCATGATGTCTGTGGACCCAACAAGGAGCTGGATGAAGACACCTGTCAGTGTGTCTGCAAGGGGGGGCTTCGGCCATCTAGTTGTGGACCCCACAAAGAACTAGATAGAGACTCATGTCAGTGTGTCTGTAAAAACAAACTTTTCCCTAATTCATGTGGAGCCAACAGGGAATTTGATGAGAATACATGTCAGTGTGTATGTAAAAGAACGTGTCCAAGAAATCAGCCCCTGAATCCTGGGAAATGTGCCTGTGAATgtacagaaaacacacagaagtGCTTCCTTAAAGGGAAGAAGTTCCACCATCAAACATGCAGTTGTTACAGAAGACCGTGTGCGAATCGACTGAAGCATTGTGATCCAGGACTGTCCTTTAGTGAAGAAGTATGCCGCTGTGTCCCATCGTATTGGAAAAGGCCACATCTGAACTAAGATCATACCAGTTTTCAGTCCACCATTTTACTCTCTTGAAGAACTGTTGCCACATTAGCACTGTCTATGCACAGAAAGACTCTGTGGGACCATGGTAACAGAGGCCCAAGTCTGTGTTTATTGAACCATGTGGATTACTGCGGGAGAGGACTGGCACTCATgtgcaaaaaaacctcttcaaAGACTGGTTTTCTGCCAGGGACCAGACAGCTGAGGTTTTTctcttgtgatttaaaaaaagaatgactatATAATTTATTTCCACTAAAAATATTGTTCCTGCATTCATTTTTATAGCAATAACAATTGGTAAAGCTCACTGTGATCAGTATTTTTATAACATGCAAAactatgtttaaaataaaatgaaaattgtatTATAAGCT