Summary

Gene Name	Cenpe
Specie	Mus musculus
Full Name	centromere protein E
Also known as	312kDa|C530022J18|CENP-E|Kif10
Coordinate	chr3:134918324-134979301
Strand	+
Gene summary	Enables kinetochore binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of attachment of spindle microtubules to kinetochore; positive regulation of protein kinase activity; and regulation of mitotic metaphase/anaphase transition. Acts upstream of or within regulation of protein stability and spindle assembly involved in female meiosis I. Located in kinetochore. Part of outer kinetochore. Is expressed in testis and thymus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Cenpe

Retroname	Coord	Strand	Genomic Region	ENSG
CenpeP1	chr1:18064052-18067954	+	Intergenic	ENSMUSG00000099591	UCSC
CenpeP2	chr6:7193298-7194254	-	Intergenic	ENSMUSG00000098421	UCSC

Expression

Transcript Sequences

>NM_173762.4

AACCTTGAGGACATTTTAAACTTAAAGGCGGGGCGGCCCGGGAGCTCGGTCGGCGCCGTTGCTCTCCTTCGTTTCCCTTAGTCTGCAGCGGACAGGATGGCCGAGGAGGCTTCAGTGGCTGTCTGTGTTCGTGTGCGACCCCTCAACAGCAGAGAAGAAGAACTTGGAGAAGCCACCCACATTTACTGGAAAACAGATAAAAACGCTATTTATCAGAGCGATGGGGGTAAATCTTTCCAATTTGATCGTGTCTTTGACAGTAATGAAACCACGAAGAATGTGTATGAAGAGATTGCGGTGCCCATCATCAGCTCCGCCATACAAGGCTACAATGGTACTATATTTGCCTATGGACAAACTGCATCAGGAAAGACACACACGATGATGGGTTCTGAAGATTGTTTGGGAGTTATACCCAGGGCAATTCATGACATTTTCCAAAGGATAAAGAAGTTTCCTGAGAGAGAATTTCTCCTACGAGTTTCTTACATGGAGATCTACAATGAAACCATTACAGATTTACTCTGTAATGCTCAAAAAATGAAACCTTTGATAATTCGGGAAGACACCAATAGGACTGTATATGTTTCTGATCTCACAGAAGAAGTGGTTTATACAGCAGAAATGGCTTTGAAATGGCTCGCAACAGGAGAAAAAAACAGACATTATGGAATAACCAAAATGAATCAAAGAAGCAGTCGTTCTCATACGATTTTTAGGATGATTCTGGAAAGTAGAGAAAAGGCTGAGCCTTCTAACTGCGATGGCTCCGTCAAAGTGTCTCATCTGAATTTGGTCGATCTTGCAGGCAGTGAAAGAGCTGCTCAAACAGGAGCTGAAGGTGTGCGATTGAAGGAGGGCTGTTTTATAAATCGGAACTTGTTTATTTTGGGACAAGTGATTAAGAAACTCAGTGATGGACAGGTTGGGGGTTTCATAAATTACCGAGATAGCAAATTGACACGAATTCTTCAGAATTCCTTGGGAGGAAATGCCAAGACGCGCATCATCTGCACGATCACCCCAGCGTCCCTGGACGAAACCCTGACGACGCTGCAGTTTGCCAGCACTGCTAAGTATATGAAGAATACTCCTTACGTTAATGAAGTGTCGAATGATGAAGCTCTCTTGAAAAGATACAGAAGAGAAATAGCGGATCTTAGAAAACAATTAGAGGAGGTAAATACAAAGACTCGGGCACAGGAAATGGAAAAGGATCAACTGGCCCAGCTTCTGGATGAAAAAGACTTGCTTCAGAAAGTTCAGGATGAGAAAATTAATAACCTGAAGCGGATGCTGGTGACGTCATCTTCTATTGCATTGCAGCAGGAGCTAGAGattaaaaggAAACGAAGAGTTACTTGGTGCTATGGCAAAATGAAGGATTCAAACTATGAAAAGGAATTTAAAGTCCCGACAAGCATAACAACAAGAAAACGTAAAACTTCTGTGACTTCTTTGAGAGAAAATTCTCTCATGAAGTTCGGAGAGAGTGCAGCCTCTTCCGAGTTTGAAATGTTGAATAACACTCTTGAGTCATTGGCTGAGGTAGAGTGGAGCTCGGCAACAACGCTCCTAAGCGAGGAAAATGTAGAAAGTGAGTTGAACTCACTTAATGCTCAATATAATGATCTGGTATTAGACTATGAACAgctcagaagagaaaatgaagacttgaaattgaaattaaaagaaaaaaatgagttagaGGAATTTGAgcttctagaacaaaaagaagaaagagatcaaGAGATGCAACTAATGCATGAAGTTTCCAACTTAAAGAATTTAATTAAACACGCAGAAGAATATAATCAAGACCTTGAGAATGACCTAAGTTCAAAAGTGAAgcttcttaaagaaaaagaggagcagATTAAGAACCTGCAGGAATACATAGATGCCCAGAAGTCAGAAAAGATGAAGATAGACCTGTCATACACATCGGACGCCACTGAAGACCTGAAACAGGCGATGCGCACCCTGTCTGATTTGGACACAGTGGCCCTTGACGCTAAGAAAGAGTCAGCCTTCCTTAGAAGTGAAAATCTGGAGCTGAAGGAGAAAATTAATGAACTTTCGGATTCCCGTAAGCAAATGGAAAGTGACATTCAGATGTATCAACGCCAACtggaagcaaaaaagaaaatgcaaactgatcTGGATAAGGAATTACAGTTGGCTTTTCAAGAAATATCAAAACTCAGCGCCCTGGTAGATGGCAAAGGTTTACTGTCTAATTTGGAATTGGAGAAAAGGATTACTGATCTCCAAAAAGAACTAAATAAAGAAGctgaagaaaaacaaactttGCAAGAAGAAGTTAACTTGCTGTCGGAGTTGAAATCTTTACCGTCTGAGGTGGAAACGCTGAGGAGAGAGCTGTATGAGAAATCTGAAGAGCTCCATATAATAaccacagaaagagagaaactgtTTTCTGAAATGGCTCATAAAGACAGTAGGATTCAAGGTTTACTTGAGGAAATTGGAAACACTAGAGATGACCTTGCCACTTCCCAGCTGAGTCGGAGGGGCAGTGATGGAGAATGGCAAGCCCTGGAAAGCCTGCACGCAGAGCTGGAGCACAGACACGCGGGGGtcctggaggagagagagaggctgaagcaggagattgGGGCTCTCTCCAAAGAAGCAGAAAGCCTGGCTTTCAGTTTGGATTCCGTGAAGGCCGAGCTTTCTCACAAGACTCAAGAGCTTGAGCAGAAAACAGTTGAGGGTCAAGAAAGGCTAAATAAAATGGAGGCGCTGAGAGAAGAGTTAGAAAGCAGAGACTCCAGCCTGCAGTCTGTAGAGAAGGAGAAAGTCCTGCTCACTGAGAAGCTGCAGCAAGCCTTGAAGGAAGTAAAAGCCTTAacccaagaaaagaaaaacctgaagCAGCTCCAGGAGAGCCTGCAAACTGAGAGAGACCAACTCAGAAGTGACATTCAGGACACTGTGAACATGAACATAGATACTCAAGAGCAGTTACTAAATGCTCTGGAGTCTCTGAAACAACACCAAGAAACAATTAACATGCTGAAAATGAAAGCTGCTGAGGAACTATCCGATAATTTGCATGTAAAGGAcaggggaggagctagagatgaaGCTCAGCAAAAGATGGATGGCATAGATGAACAGAATGAGAGTGCCCACACATTGCTTGGTGGTGGTAAGGACAATGAGGTAActgaggaacagaggaaaatcGACTCTCTAATGCAGGAGAATAGCGGACTCCAACAGACACTGGAAAGTGTTAGAGCAGAAAAGGAACAACTGAAGATGGACCTAAAGGAAAATATCGAAATGAGTATTGAAAACCAGGAAGAGTTAAGAATTCTTAGAGATGAACTGAAAAGACAACAAGAGGTAGCTGCACAGGAAAAGGATCATGCCACCGAGAAGACCCAGGAGCTCTCCAGGACGCAGGAAAGATTGGCAAAAACAGAAGAGAAGTTAGAGGAAAAGAACCAGAAACTCCAAGAGACACAGCAGCAACTTCTTAGTACACAAGAAGCTATGAGTAAGCTGCAGGCAAAGGTGATTGACATGGAAAGCTTACAGAATGAATTCAGGAACCAAGGATTGGCATTGGAGCGTGTGGAGACAGAGAAACTGGAGTTAGCTCAGAGACTTCATGAAAGTTATGAGGAGGTGAAATCTataaccaaagaaagaaatgatctaAAGGAATTGCAGGAGTCATTTGAAATAGAgaagaagcaacttaaagaataTGCAAGGGAAATAGAAGCCGCGGGCCTACAAACAAAAGAAGAACTAAACATTGCCCACGCGAATCTAAAAGAGTACCAGGAAATCATCACAGAGCTAAGAGGAAGCATTTCTGAAAACGAAGCACAAGGAGCAAGCACCCAGGACACGGCAAAAAGCGCCCCTGAGCTACAAGGAGAGGTTCCAGAGCAAGAGCTGCTTCCTGTTGTCaaagaagccaggcacagtgcAGAAAAAGTGAACGGACTGGAGCCAGTGGGAGCACATTCCAGAACAGTGCACTCCATGACAATGGAGGGCATAGAAATAGAAAACCTCAGGCTGACCAAGAAACTTGAAGAAAGTCAGATGGAGATCAGCTGTCTcactagagagagagaagacctgAGAAGGACACAGGAAACACTTCAGGTCGAATGTACCCAGCTGAAAGAAGATGCCAGAAGAACTTTGGCTAATCATCTAGAAACTGAAGAGGAACTTAACCTTGCTCGTTGTTGCCTGAAAGAGCAGGAGAACAAGATTGACACCCTAATAACGAGCCTCTCGCAGAGGGAAACTGAGCTGTCCAGTGTGCGAGGACAACTAGCGCTGACTACTGCTGAACTGGAGAGAAAGGTTCAAGAACTCTgtgagaaacaggaagaactTACTAGGAAAGAAACTAGCGAGGCTCAAGGGAAGATGAGTGAACTAGAGCAACTCAGGGAGCTGCTGCTTGCCCAGGCCTCGGCACTGCAGAACGCAGAGAGTGACAGGCTGCGGCTGAATACACAACTGGAAGAAAgtcaagaggaaatgaaaactctaagggaggaaagagaagagctgAGAAGAATGCAAGAGGCTCTTCACGTGGAAAGTGAGCAGCAGAAAGAAAGCATGAAGGAAATCAGCTCAAAACTCCAAGAACTACAGAACAAAGAGTATGAATGTCTTGCAATGAAGACTATTAATGAGACTCAAGGAAGCAGATGTGAAATGGACCACTTGAACCAGCAGCTGGAGGCCCAGAAGTCAACTCTGGAAAAGGTGGAGATGGAGAATGTAAACTTGACTCAAAGACTTCATGAGACCCTTGAGGAAATGAGATCTGtagcaaaagaaagagatgagCTTTGGAGCATGGAGGAGCGCCTCACAGTAGAGAGAGACCAACTGAAGAAGAGCCTTGAAGAAACAGTAACTAAAGgtatggaaaaagaggaagagctaAGAGTTGCGCATGTGCATCTGGAAGAGCACCAGGAAACTATCAACAAGCTCAGAAAGATGGTGTCTGACTACACAGATGAAATATCACATACTCAAGGGGACCTAAAGCACACAAATGCCGTTGTAGAAGCTCAGAACCAAGATCTCCGGGAAAAAGAACATCAACTTTCTCAAGTAAAAGCTGATCTCAGAGAAACCGTGGATCAAATGGAGCAACTGAAGAAgaagctcgaagcccagagttcGACTCTAGAAAGCAGAGAAATAGAGAAGTTAGAATTGACTCAGCAACTTAAcgaaaaccttaaaaaaataacacTTGTCACTAAGGAAAATGATAGCCTAAAAATTATGGATGAAGCCCTCAGGGAAGAACGAGACCAGCTACGGAAAAGTCTTCAGCAAACAGAGGCAAGGgatctgGAAAATCAAGAGAAACTAAGAATTGCTCACATGAATCTAAAAGAGCACCAAGAAACTATTGACCGACTCATGGAGACTATGTCTGAGAAGACAGAGGAAATATCAAATATGAAAATGGagttagaaaatgtaaacatgaaATTACAAGAAAAGGTTCAAGAACTTAAGACAAGTGAGCGTCAACGTGTTAAGTTAAAAGCAGATGCCAGTGAAGCCAAGAAGGAGCTCAAGGAGCAGGGCTTAACTCTGAGTAAGATAGAGATGGAGAACTTAAATCTCGCTCAGAAGATTCATGAGAACCTTGAAGAAATGAAATctgtaagaaaagaaagagatgatcTAAAGAAACTTGAGGAGATACTCAGAATGGAGAGAGACCAGCTCAAGGACAACCTGAGAGAAGCCATGCTTAAGGCCCACCAGAACCATGAAGAGACAATGAAATGTGGAAAGGGGTTACTGTGTGCTGGAGAATACTGTACAGGAAGACTTCGAGAAAAGTGCTTCAGGATAGAAAAACTCCTGAAAAGATACTCAGAAATGGCTAATGATTATGAGTGCTTGAATAAAGTCTCTCTTGACTTggagagagaaactaaaacccaAAAAGAGCTGTCAGTTACTGTAAGAACAAAGCTCTCACTTCCGCACACACAGACCAAAGAGATGGAAAAGCTTCTGACTGCAAACCAGAGATGTTCCCTGGAGTTCCACAGAGCCCTCAAGAGACTTAAGTACGTGTTAAGCTCCATTGCGAGGATAAAGGAAGAGCAGCATGAGTCCATCAATAAACGTGAAATGGCTTTTATTCAGGAAGTGGAAAAGCAGAATGAACTGCAGATTCAAATCCAGAGCCTTTCACAGACTTACCGTATTCCAGCCAGAGACTTACAGATCAAACTGAGCCAGGAGATGGACCTCCATATTGAgGAAATGCTCAAAGATTTTTCAGAAAATGATTTCCTCACCATAAAAACTGAAGTCCAACAAGTATTAAATAATAGGAAAGAAATAACTGAGTTTTTGGGAAAATGGCTAAATACTCTTTTTGATACAGAAAATCTTAAGAGCACcatccagaaagaaaacaaaagcattgGGCTCGTGAATAACTTCTATCACAGCAGAATCACTGCCATGATAAATGAATCAACGGAGTTTGAGGAAAGAAGTGCTACCAGATCCAAAGACTTGGATCAGTACCTGAAGTCACTGAAAGAAACAACTGAGCAACTGTCTGAAGTCTACCAGACACTGACCGCCTCCCAGTCTGTTGTGCATCTCCATCCTACCGTGCAGCCTTCCACACGGGACAGTGAGCGTCCTCAGGCTGCATCAGGAGCTGAACAACTGACCTCAAAGAACAAAATTGCTTTAGGAGCTGTGCCCTATAAAGAAGAAATTGAGGATCTCAAAATGCAGCTGGTGAAGAGTGACCTAGAGAAGAAGGCGACCGCCAAGGAATTCGATAAGAAAATTCTCTCTCTAAAAGCCACTGTTGAACATCAAGAAGAAATGATAAGGCTACTGAGAGAAAATCTTAGAGGACATCAACAGGCCCAGGATACCTCAATGATCTCAGAACAAGACTCTCAGCTTCTGAGTAAACCTCTAACCTGTGGAGGTGGCAGTGGAATTGTACAAAGCACAAAAGCTCTTATTTTGAAAAGTGAATATAAAAGGATGGGAAGTGAGATTTCTAAGTTAAAGCAGCAAAATGAGCAGCTAAGAAAGCAAAATAATCAACTATTAAGTGATAACTCTCAACTCTCCAATGAGGTTAAAACCTGGGAGGAAAGAACTCTTAAAAGAGACAGTTACAGAGAAACAACTTGTGAGAATTCTCCAAAGTCTCCTAAAGTGACTCGGACAGATTCTAAAAGGAGACAGAACACAACTTCTCAGTGCAGGGCACAAAATCTCCAGGATCCTGTGCCAAAAGATTCCCCAAAATCATGGTTTTTTGATAACCGGTCAAAGTCTCTTCCAGCACCTCACCCGATCCGCTATTTTGACAACTCCAGTCTAGGGCTGTGCCCAGaACCAGATGACGTAGAGAATGTGGAGCCTAAGACAGACCTCTGCCAAGCCTCCTTGGAAAAAGATGTGTCCCAGTGCAAGACGCAGTAGATGCCCCTGTCCCGTCAGAGCAGAGCGCCCTTGGATGGATGCCCCCGTCAGCCGAGCGCTCTTGGATGCCTTTCCTCGTGTGTCCACACTGACAAAGATGATGCAATCCAACTTAGTTTCAGTCTAATTTCCACTTTAGAAGATGGAGGAACAAGAAACGGATTGATTGCAGTGACTTAGAACGCTGGTGGCAGTTCTTTCTGCTTGCATCTGTGACATTCCACACGCTGAActgttaattatttatttttatacattgcgAAGAATAAAGGTCTTGAAGGAAAATTTTAATCTTTCCAGA