Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Tardbp
Plot displaying the genomic locations of a parental gene (in chr4) and its retrocopy(ies). Each line represents a retrocopy.
Specie Mus musculus
Full Name TAR DNA binding protein
Also known as 1190002A23Rik|TDP-43|Tdp43
Coordinate chr4:148696839-148711453
Strand -
Gene summary Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and pre-mRNA intronic binding activity. Involved in positive regulation of protein import into nucleus; regulation of circadian rhythm; and regulation of protein stability. Acts upstream of or within RNA splicing. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and heart. Used to study Grn-related frontotemporal lobar degeneration with Tdp43 inclusions; amyotrophic lateral sclerosis type 10; and frontotemporal dementia. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 10; and motor neuron disease. Orthologous to human TARDBP (TAR DNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Tardbp

Retroname Coord Strand Genomic Region ENSG
TardbpP1 chr2:104650522-104652527 + Intergenic
 ENSMUSG00000083856 UCSC

Expression

Transcript Sequences

>NM_145556.4
CTCGGAAGGCCGAGTGGCCGTTCTGTCCTTCATCTGTCAGTTTTTCAGACCCAGCTGTTTTCATTGTTGcgtttctttacttttttctatACGCCGAAGAGCCTGCTAGCATCCGAGCCTCTGGGAGGAGAGAGCGCCTGTGGCTTCCCTCGGAGAGCGCCCCTCCTGCAGGGAAGCCAGTGGGAGAGGCCGAAGGCGGGCGAGGGCGGGAGGCGGCCCTAGCGCCATTTTGTGGGCACGGAGCGGTAGCGCGGCTGTTGTCGGATTCCTTCCCGTCTGTGCTTCCTCCTTGTGCTTCCTAGCAGTGGCCTAGCGGagATTTAAGCAAAGATGTCTGAATATATTCGGGTAACAGAAGATGAGAACGATGAACCCATTGAAATACCATCAGAAGACGATGGGACGGTGTTGCTGTCCACAGTTACAGCCCAGTTTCCAGGGGCATGCGGCCTGCGCTACCGGAATCCCGTGTCTCAGTGTATGAGAGGAGTCCGACTGGTGGAAGGAATTCTGCATGCCCCAGATGCTGGCTGGGGCAATCTGGTATATGTTGTCAACTATCCCAAAGataacaaaaggaaaaTGGATGAGACAGATGCTTCCTCTGCAGTGAAAGTGAAAAGAGCAGTCCAGAAAACATCTGACCTCATAGTGTTGGGTCTCCCCTGGAAAACAACTGAGCAGGATCTGAAAGACTATTTCAGTACTTTTGGAGAGGTTCTTATGGTTCAGgtcAAGAAAGATCTTAAAACTGGTCACTCGAAAGGGTTTGGCTTTGTTCGATTTACAGAATATGAAACCCAAGTGAAAGTAATGTCACAACGACATATGATAGATGGGCGATGGTGTGACTGTAAACTTCCCAACTCTAAGCAAAGCCCAGACGAGCCTTTGAGAAGCAGAAAGGTGTTTGTTGGACGTTGTACAGAGGACATGACTGCTGAAGAGCTTCAGCAGTTTTTCTGTCAGTATGGAGAAGTGGTAGATGTCTTCATTCCCAAACCATTCAGAGCTTTTGCCTTCGTCACCTTTGCAGATGATAAGGTTGCCCAGTCTCTTTGTGGAGAGGATTTGATCATTAAAGGAATCAGCGTGCATATATCCAATGCTGAACCTAAGCATAATAGCAATAGACAGTTAGAAAGAAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGGTTTGGTAACAGTAGAGGGGGTGGAGCTGGCTTGGGAAATAACCAGGGTGGTAATATGGGTGGAGGGATGAACTTTGGTGCTTTTAGCATTAACCCAGCGATGATGGCTGCGGCTCAGGCAGCGTTGCAGAGCAGTTGGGGTATGATGGGCATGTTAGCCAGCCAGCAGAACCAGTCGGGCCCATCTGGGAATAACCAAAGCCAGGGCAGCATGCAGAGGGAACCAAATCAGGCTTTTGGTTCTGGAAATAATTCCTACAGTGGTTCTAATTCTGGTGCCCCCCTTGGTTGGGGGTCAGCATCAAATGCAGGATCGGGCAGTGGTTTTAATGGGGGCTTTGGCTCGAGCATGGATTCTAAGTCTTCTGGCTGGGGAATGTAGGTGGTGGGGGGTGGTTAGTAGGTTGGTTATTAGGTTAGGTAGATTTAGAATGGTGGGATTCAAATTTTTCTAAACTCATGGTAAGTATATTGTAAAATACATATGTACTAAAATTTTCAGATTGGTTTGTTCAGTGTGGAGTATATTCAGCagtatttttgacatttttctttagaaaaaaagaggggaaagctaaatgaattttataagtttTGTTATATAAAGGGTTAAAATACTGAGTGGGTGAAAGTGAACTGCTGTTTGCCTAATTGGTAAACCAACACTACAATTGATCTCAGAAGGTTTCTCTGTAATATTCTATCATTGAAATTGTTAATGAATTCTTTGCATGTTCAGAGTAGAAACCATTGGTTAGAactacattcttttctccttattTTAATTTGAATCCCACCCTATGAATTTTTTCCTTAGGAAAATCTCCATTTGGGAGATCATGATGTCATGGTGTttgattcttttggttttgtttttaacacttGTCTTCCTTCATATACGAAAGTACAATATGAAGCCTTCATTTAATCTCTGCAGTTCATCTCATTTCAAATGTTTATGGAAGAAGCACTTCATTGAAAGTAGTGCTGTAAATATTCTGCCATAGGAATACTTCTGTCTACATGCTTTCTCATCCAAGAATTCGTCATCACGCTGCACAGGCTGCGTCTTTGACGGTGGGTGTTCCATTTTTATCCGCTACTCTTTATTTCATGGAGTCGTATCAACGCTATGAACGCAAGGCTGTGATATGGAACCAGAAGGCTGTTTGAACTTTTGAAACCTTGTGTGGGATTGATGGTGGTGCCGAGGCATGAAAGGCTAGTATGAGCGAGAAAAGGAGAGCGCGTGCAGAGACTTGGTGGTGGAAAATGGATATTTTTTAACTTGGAGAGATGTGTCACTCAATCCTGTGGCTTTGGTGAGAGAGTGTGCAGAGAGCAATGATAGCAAATAACGTACGAATGTTTTACATCAAAGGACATCCACATCAGTTGGAAGACTTTGAGTTTTGTTCTTAGGAAACCCACTTTAGTTGAATGTGTTAAGTGAAATACTTGTacttccctccccctctgtcaACTGCTGTGAATGCTGTATGGTGTGTGTTCTCCTCTGTTACTGATCTGGAAGTGTGGGAACGTGAACTGAAGCTGATGGGCTGCGAACATGGACTGAGCTTGTGGTGTGCTTTGCAGGAGAACTTGGAAGCAGAGTTCACCAGTGAGCTCAGGTGTCTCAAAGAAGGGTGGAAGTTCTCATGTCTGTTAGCTATTCATAAGAATGCTGTTTGCTGCAGTTCTGTGTCCTGTGCTTGGATgcttttttataagagttgtcattgTTGGAAATTCTTAAATAAAACTGATTTAAATAATATGTGTCTTTGTTTTGCAGCCCTGAATGCAAAGAATTCATAGCAGTTAATTCCCCTTTTTGACCCTTTTGAGATGGAACTTTCATAAAGTTTCTTGGCAGTAGTTTATTTTGCTTCAAATAAACTTATTTGAAAAGTTGTCTCAAGTCAAATGGATTCATCACCTGTCATGCATTGACACCTGATACCCAGACTTAATTGCTATTTGTTCTTGCATTGTCCAAAGTGAAagtttttctttggtttgtttttaatttagtttttcttAAGTCTGGGTGACCGCACCTAAAATGGTAAGCAGTTACCCTCTGGCTTGTTCTGAGTGCCTCTGTGCATTTGATTTTCTATTTACATGCTGTATAAATCTCCACTGGGGAATCATGCCTTCTAAAAATATTTGGGAGAGGGCAAAAGAGTTGATTTCTAATGCTTTGTAGCAGAGCATATCAATGGGAAAGAAGGTTAAGCACCTTTCTGTTTGGGATTTGAAAAGTGGAATTAATTGCAATAGGGATGAAGTAGAAGAAACCAAGAAACCATGTGCCTGAAATACATTAAGAAGCCTGATTGATAGCTTTAAGAACTAGTAGGGTGGGTTGTCTTACCTGTGGCAGTCTTAAGTGAGGTAGGCTTTTGCCCTCCTGAATGTGGGGGTTATGTAGTGATGAATATGCTCACAAAATCAGATTAGACTGTCAATGCATTGTTAATGTAAAAGCAATAATACATTGATTATTGTACTTTTCCTGTAACTACTGAGACCGGAGGCGCTCCTTTTCTAACTGGAAGAATGGGACAGTTTTTGTGTTGGTAGTTTTTCCTAATGCCCTTACCTAAATAGATTATGATAAATAGGTTTGTCATTTTGCAAGTTgcgtgttttaaaattttatatccgTTAGAGACTTGTTATGAACACATTGTTTCATTATACAGTATCCTCTGTAAAAGGATCGTGAGTTATTGTAAGtttttttctctgcatctaacccTGCATGATTTCCAAACCCTGTGCATCTGAATTTTGCATTTTAGCACTGTTTGCACTGTTACTCAGCAGCAGTAACATGGTAACATTAAAATGGTTTTCGGGGACCTCCAAAGACGGCCAGGAGTCCTGGGGTAAGTTACTTGTCAATGGCATGGTTTTGATCCCTTTTTTACACTTGTTAAAGACTTACTGGTCATAGAAGTCTTTCAGTGTTGATCAGCCTTTTAACATGTTTATGGATGACATAGCTGTAGTTAGTTACTTGCCGTAAATGAGGTTTTAGAAATAAACTACTTGGCAAAGATTTGGTTTTGAAAGTCTGGTCATCAAAACGCGTTCATTCCTTAGAAATAATGAAGAACAACTCTTTGAACCACAGTTGAATAAAAGGTTTTCTTGCCACCAACAGTTTAGTGTCTGGAGTcttactggaagaaaaaaaaattctatatcaTGACAATGCTAGAAAAGTTAAGGTGACTTATGTGGGAAGATGCAATATAGCATTTTCATCCTTTAAAATTTGAGTCTCcaggtgggtgtggtggcccatgcttttaatcccagaattggTGTAAATGAGTTGTAGGCCAGCTATTTCCCCATCTTGAGGCACCCTGTCTTGCCTTGTTGGAAGAGCCAGTTAAAATCAAACATGACCTTTAAGGTCAGCATCTTAGCAGAAGAGCAGTTTATTTCAGGATAACTTACTGTTTTTGATACATAAGCAAATGACTGTACCTTGTACAGTTACGGTTGACTTCCCTGAGCCCAACGCTCACCTAAGAAAAGTGGGCTGGGTATAGTGAAACACCTGTTAAGGTTTTTGGAATGATTTGCTAAATTGCCCTTGTAAAGGGTAAAATGCTGTTTCGTGTTCTTTTTATCTGACAATTTGGTGAATCTGGTAGAACATGCCTATATCCCAATATTCTGGAATGGACTTGGTGTTAATTTAATAGCTGATCTAATGTGAAGGTCACACACCTGCTTTCCGCTTACCTTCCAAAAGGTATTCTGGAACCACTCAGAAGTTACTCAGAAAGTAAGAGCACTTTCTGAGCTCATTAAGACCAAATCTACACACTAGACACAACAAGCCCTTTGTTGGCCAGAAATGGAAACAGCCAGTATAAAATAAGTAGATTGTAGGGAATCAAATACAACTTGTTTTTTCTGTGTTGGGGGTTGGCCAAGCACTGTTAAACACAAATCAAAGCTGATATTGGCAAGTGTTTGGACCTGTAACAATCTCACCTGCTCTGATTTTGGGGTAGGCTGTCATTCTTAGGTTTGTTACTAAGCTTCCCAGGTACTTGGCGATATGAGGAACAATGATTGGACGATGCAAATTAGAAATTACTTATTATGTTCTCAATCCAGGGAATATAGTTGATGACTTTTGTGTAGACCCCATACTGGTCTGCCGCCCCACAATTAATGGAACCCCAGGAAACTATTCCTCCCACAAACCATCGCTGTGTCTCATTATCTAGAAACACTAATGCCCCCCCACTGTCACCTCTGCAGCTGTCCTTGCCACCAGTCTCTAAGCCAGCACAGAGCATGTTAGCGCTTACTCTTACTCCTGGATAGAGCTTTTCATACACGGCGGTACATTTTTGGTGGTCAGCAATTGGTATGTCCACAAACATTAGGTTTCTAGCAAGAAGCCCCTTCTGGGTTAACCCCCAGCCAGCCACAGTTCCAGTGAAGTCTGTTCTCATTAAGGATGCAGCTTCTTTTCGCGGTAGGCAAACAGGCATGATGCTTCCGTTGATTGTGACTTTGTTCTTGAGTTTAATCAATGCTATATCATTGTCAAAACCAGCACCGTGAGTGTAGCCTTCATGTATAAAGATTTCCTCGGGCCAGGCTTGAGTGTAATGAGGTGAGAGCCTTTTGAGGATGCCCATTCGGATGTTCAGGGAGGACGCTgccattcttttctcatatacaGCATGAGCGGCTGTTAGGACCCAATTGTCATGTATAAGTGCACCTGCTGCTGCTGTAGTTTGACCCAGCAACAAGACTTGCCAAGGAAAGTCACCAGGCTTTGCAGGCTGCCCTCCAACTATGCGTCCTCCTATAGTGTGTGTGGACAGCCCACAAACTGAGGGATAAAAAACAAGTATTTAATGCCCTACAAATTGATAGGCATCCTCCCTGTTGAGTGAGGCTATTTAAGTTTTTGTTTAGCCTGCTCACCTCCTTGTAAAGATCAGTAAGAGATCTCAGAGATTGTTTTGCTGAAAGAGAACAGCATGAGGGAGTCTGGACAGGACTTGTGTGCAGGAGGACATGACACTACTTAGAGGCCAAAGACAACCCCCTCACCACACCCTGAGctgcttgtttttctctttttgggCTCTCTGGGAATTCTGGGAAAGCAGGAACTATGATTTACAAAGTTTCTGTTGTCTTTAAATGTAAGACTCTAAATTACAATGTTGCAGCAATAGCCAAAGTGCTTCTGGTTCAAAAATTGGTAATTTTGGTCTGGTGGAGCCCTCCAAACACTTTTACCGTTCTTTGCAAACTGAGGGCTCAGGAATGCAACACATGTTCTTTATTGTGGTTGTGCACTTTGATTAAAACTTGGAAGCCGCATGTCAGCCAAATACAAGGCTAGAAAACTAATTTAAACCAGCTAACACGGGGGTAATGAGTGTATTATTacctttcaattaaaaaaaaagcactctCAACTGTTGTTGGAGCCAATTCTGGTAAAGAAATTTAAGTACTATTAAAAGGCAAATTGCATTAATGTTTAAAAATCTTGATGTCGTTGAAAACAATTGCTTAGGGAAATAATGAAGTTATTAGCTTTGGGGTTTAATAGCAtttttacagagaagaaaagtAACAAGAGTTCTTGGTTATAAATGTATAAACGGTTTGAGATAATTtaagaaatcatttaattttttatgctTGCCTAGTTATAAGGTCAAAAACAATCAAGTGCATGATGCACCTAGCTTCCGTGTGGAAGGGGaaatgtgagcacactgttgGGAAACACTAAGCTCCAGCCTCAGCCAAGTGCTGAgctttctgcctccccagccagACCCTGCCTATTGTCTGCCAGCTACTCTGTCAGCTATGAATCTCTTTTATAAATGGCGTCCATTACCAGGCTCACAAACCGGGGGGAGTTTTTCTCCTTTGGAGCTCGTCCAGAATCCATCAGCCTCACACACATATTTACCTGCAAGTCATTGGAAAAGCAAAAATGTTTAGCTGTAGTTGTCATTTGCTTGAATAACCCCTTGAAAAATGTTGATTCTTGAGCATCTGTGGTGGGGAGAGGTGTGTGAATAACCATTTTACATGATTTCATAAATAGGTGTCTGCATTACCATGTTTGCTTGCAAAGTGGAAACCTTTTAGATGTGTAACTTGAATATGTATCAAGATCTCAAGTGCTTAATGATAAGGTTTTGACTTGTTAAATTAAACCATTTGGAATATATTGTG