| Gene Name | SLC39A14 |
|
| Specie | Homo sapiens | |
| Full Name | solute carrier family 39 member 14 | |
| Also known as | HCIN|HMNDYT2|LZT-Hs4|NET34|ZIP14|cig19 | |
| Coordinate | chr8:22367278-22434129 | |
| Strand | + | |
| Gene summary | This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| SLC39A14P1 | chr1:235614867-235620069 | + |
Intragenic |
ENSG00000227236 | UCSC |
| >NM_001351655.2 |
| GCCCGGACGCAGTGAGGGGGGTCGGCGCGCGTGTCTACGCGGACGCACCGGCTAAGCTGCTTCTGCCGCCGCCGGCCGCCTGGGACCTTGCGGTGAGGCTGCGCGGGGCCGAGGCCGCCTCCGAGCGCCAGggtctcgctcttgtgcaggctggagtgcagtggtgcaatcatagcttgttgcagcctcaaactcctgggttcaagcaatcctcccacctcagcctctcacactgctgggattacagggGTTTATTCAGTCACCATGAAGCTGCTGCTGCTGCACCCGGCCTTCCAGAGCTGCCTCCTGCTGACCCTGCTTGGCTTATGGAGAACCACCCCTGAGGCTCACGCTTCATCCCTGGGTGCACCAGCTATCAGCGCTGCCTCCTTCCTGCAGGATCTAATACATCGGTATGGCGAGGGTGACAGCCTCACTCTGCAGCAGCTGAAGGCCCTACTCAACCACCTGGATGTGGGAGTGGGCCGGGGTAATGTCACCCAGCACGTGCAAGGACACAGGAACCTCTCCACGTGCTTTAGTTCTGGAGACCTCTTCACTGCCCACAATTTCAGCGAGCAGTCGCGGATTGGGAGCAGCGAGCTCCAGGAGTTCTGCCCCACCATCCTCCAGCAGCTGGATTCCCGGGCCTGCACCTCGGAGAACCAGGAAAACGAGGAGAATGAGCAGACGGAGGAGGGGCGGCCAAGCGCTGTTGAAGTGTGGGGATACGGTCTCCTCTGTGTGACCGTCATCTCCCTCTGCTCCCTCCTGGGGGCCAGCGTGGTGCCCTTCATGAAGAAGACCTTTTACAAGAGGCTGCTGCTCTACTTCATAGCTCTGGCGATTGGAACCCTCTACTCCAACGCCCTCTTCCAGCTCATCCCGGAGGCATTTGGTTTCAACCCTCTGGAAGATTATTATGTCTCCAAGTCTGCAGTGGTGTTTGGGGGCTTTTATCTTTTCTTTTTCACAGAGAAGATCTTGAAGATTCTTCTTAAGCAGAAAAATGAGCATCATCATGGACACAGCCATTATGCCTCTGAGTCGCTTCCCTCCAAGAAGGACCAGGAGGAGGGGGTGATGGAGAAGCTGCAGAACGGGGACCTGGACCACATGATTCCTCAGCACTGCAGCAGTGAGCTGGACGGCAAGGCGCCCATGGTGGACGAGAAGGTCATTGTGGGCTCGCTCTCTGTGCAGGACCTGCAGGCTTCCCAGAGTGCTTGCTACTGGCTGAAAGGTGTCCGCTACTCTGATATCGGCACTCTGGCCTGGATGATCACTCTGAGCGACGGCCTCCATAATTTCATCGATGGCCTGGCCATCGGTGCTTCCTTCACTGTGTCAGTTTTCCAAGGCATCAGCACCTCGGTGGCCATCCTCTGTGAGGAGTTCCCACATGAGCTAGGAGACTTTGTCATCCTGCTCAACGCTGGGATGAGCATCCAACAAGCTCTCTTCTTCAACTTCCTTTCTGCCTGCTGCTGCTACCTGGGTCTGGCCTTTGGCATCCTGGCCGGCAGCCACTTCTCTGCCAACTGGATTTTTGCGCTAGCTGGAGGAATGTTCTTGTATATTTCTCTGGCTGATATGTTCCCTGAGATGAATGAGGTCTGTCAAGAGGATGAAAGGAAGGGCAGCATCTTGATTCCATTTATCATCCAGAACCTGGGCCTCCTGACTGGATTCACCATCATGGTGGTCCTCACCATGTATTCAGGACAGATCCAGATTGGGTAGGGCTCTGCCAAGAGCCTGTGGGACTGGAAGTCGGGCCCTGGGCTGCCCGATCGCCAGCCCGAGGACTTACCATCCACAATGCACCACGGAAGAGGCCGTTCTATGAAAAACTGACACAGACTGTATTCCTGCATTCAAATGTCAGCCGTTTGTAAAATGCTGTATCCTAGGAATAAGCTGCCCTGGTAACCAGTCTCTAGCTAGTGCCTCTTGCCCTCTCCTCACCTCCTTTTCTCTCAGTGACTCTGGAACCTGAATGCAGCTTACAAGACAAGCCTGACTTTTTTCTCTGATTACCTTGGCCTCCTCTTGGAACCAGTGCTGAAAGGTTTTGAATCCTTTACCCAACAATGCAAAAATAGAGCCAATGGTTATAACTTGGCTAGAAATATCAAGAGTTGAATCCATAGTGTGGGGCCCATGACTCTAGCTGGGCACCTTGGACCTCCAGCTGGCCAATAGAAGAGACAGGAGACAGGAAGCCTTCCCATTTTTTCAAAGTCTGTTTAATTGCCTATTACTTCTCTCAAAGAGAACCTGAAGTCAGAACACATGAGCAGGGTGAGAGGTGAGGCAAGGTTCATCCTGAATGGGAGAGGAAGTCGAACCACTGCTGTGTGTCTTGTCAGGATGCTCACTTGTTCCTACTGAGATGCTGGATATTGATTTTGTAACAGCACCTGGTGTTTCACGGCTGTCCGAGTGAGCTAACGTGGCGGTGTGGCTGCCTGGACCTCCTCTTTCAGGTTAACGCTGACAGAATGGAGGCTCAGGCTGTCTGCAAGAAAACAGTTGGTTTGGCTGTGATTTTGACCTCCTCTTCCCCACTGCCATCTTCTAAGAGACTTTGTAGCTGCCTCCTAGAAGCACATTCTGAGCACATTTGAGACCTCTGTGTTAGAGGGGAGACTGCACAAACTATCCTCCCCCAGGTTGAGACGTCTGCAGAGTGGCAAGCTGACTTGTAGAAATGGGGTGCCATTTATGCTCTACTTAGACAAGGGTAATCAGAAATGGAATCAGTGCAGGCAAAATTTAGGATTTGCCGCTTCCATAAATCAAAGCATGACTAATAGGGGGTCTCTGAAATGTAAGGGCACAAACTTCACTTAGGGCATCGCAGATGTTTGCAGAATGGTTGGCCTAATGATTATGCTACAGATGGGTTTTAAATGACCCGTCTAGGTTACTGCTTCCTTGCAAAAAAAGTCGAATCCTGCATTGAATTGAATATGAATTTCTCTAACTCTCTCCAGAAAATGGATGGAGATAACTTGTCTTTAAAACTGTAGGCCAGCCTTAGCCACTGTGGAGCCCTTGCCTCCGAGCTCTGGCTTCAAGGGGAGCTCTTCTCCAGGTTCACTAGGTGAATTGATTTATTATTATCATATTGATAATGTGAGATTCTTTAGCCACTTTGGGGAGCCTGTCTCTCCAGAAGCCTTTCTTAGTGGTGCCCACAGTTGGAGCCCAGGGGCCATGTTTGCAAACTGATTCATGTGCATGGCTGACAGGAGTACTGGTTCACTACCAATGCCTGAGCTTTTCTCTTACATAGAAAAACTGTCCGCTCTCAGTAATCACAAGCAGCATCCGTTTTGTTTTCTCTTCTTGGGAGACATCTGTCAAACCAGGAATATTCTTGAAAAGAACGTGAGCAGGAAAAACTGCTGGTGATACTTTTTTTAAGTTTTGTTTTTATCTTGCCTGTTGGCTTCAATACATTTGAGAATACGCTGAAGAGGGAAAATTTCAGTGATGGAGATTCTAGATTAAATATCAGGACTGATTTCCTGGTGGGATTATGGTCCAGTTTTACCAAAGAACCAATTCCTTGAATGTTGGAATCTAACTTTTTATATTGTCATTATTATTGTTGTTTTTAAACGGTTCTTTGTCTTTTCTGTTTTATTTTTCTCAAGCTGCTTTCAGGAGCTAGCAGAAAATAACTCAAAGTTGAAGACTCTGGAAGATTTTGCTTTAACCTAACTCGCATTGATGTATTAAATTTATAATTTTAGCATTCCCAATAGATCCTATCATTCCTTAAACATAATACCCTTTGTCTTGGAGTAGAATACTAAGTTAGAGTTAGTGGATTTCTAGTTTAGGAGAGGAGCTCAAAACTATAATCTTTAACAAATTGAAAAATGAAATAGGGTGTTTTCCCTTTTTGTGCACACCTATATTACCTTAAGAAATTTCCTTCCATAGACAGCTGCCTCAAAGGGAAATCCTCTTTAAACCGTAGTTGGCGCAGAGGTCAGTCCTAGTCGGAGCTTAGGAGGGGCGGAGACGCTCACATCGTCTGACTTGAGTCGCCACTGATTGTGGCAACAGCTTTGCCTCATGAGTCAAAAATTGGCAATTTCTTTTGATTTTTAGTTGTTGAATTTGCTGTTTCAAGCATTTGTACATATTAGAAGTCTAAGGAGTAGCAAGTCAGTGGGAGGACTTTTTCACCCCTGGCATTAGCAGCTTCGACCTCATTTTCCAGATGCACCAGCTCCTATTAATAAGTTAGCAAGGAAAGTGTATGTCACGTGCAGGAACAGTGAGGCAGGGACAGGGGTTCTGCTCCTTCTCACTTCACCACCGGCACACAGCTTGCCCCTGTCTTTGCCCCCAAAGGTATTTTGTGTCTAGTGTCAAATTGGAGCTATTCTTCACTGGTCCTTAACCTTGGGTTTTAAAAAGAAGGCTTCTCTGTTTGGGTAGCGTAAGAGCTGAGTATAGTAAGTCCTCTTCCAAAGAGATGGCAATATGCTGGGCATCTACTTTAAAACAAAGTTGTCTGATTTTTGCAAGAGAGGTTAGGATTTTATTGTTCTTATTTCCCTTTACAGTTCTGCAGTTCCATCACAGTATTTTTTTAAATAACTCAGGTGTATGAGAAGAAATTAGAAAAGAAAATTAACTTATGTGGACTGTAAATGTTTTATTTGTAAGATTCTATAAATAAAGCTATATTCTGTAATTGTTGAGAATCCCACGGGTGATCATTTGCAATAAATGTGGATGTAATGAAGGCTGTTGAA |