Summary

Gene Name	Setd2
Specie	Mus musculus
Full Name	SET domain containing 2
Also known as	4921524K10Rik|KMT3A
Coordinate	chr9:110361368-110447701
Strand	+
Gene summary	Enables histone methyltransferase activity (H3-K36 specific). Involved in endodermal cell differentiation; histone H3-K36 trimethylation; and stem cell differentiation. Acts upstream of or within several processes, including animal organ development; peptidyl-lysine methylation; and tube morphogenesis. Located in chromosome and nucleus. Is expressed in 1-cell stage embryo; 2-cell stage embryo; 4-cell stage embryo; 8-cell stage embryo; and inner cell mass. Human ortholog(s) of this gene implicated in carcinoma (multiple); gastrointestinal system cancer (multiple); idiopathic pulmonary fibrosis; and malignant mesothelioma. Orthologous to human SETD2 (SET domain containing 2, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Setd2

Retroname	Coord	Strand	Genomic Region	ENSG
Setd2P1	chrX:93417847-93418665	-	Intragenic	N/A	UCSC

Expression

Transcript Sequences

>NM_001081340.2

CGGCCGCCTCCCCTCCGGTCCCCTCCCCCGCATCGGCCTGCCGCGGGGAGGGGGCTAGCGTCGCCGCCTCCAGCCGCTCCTCATGAAGCCGCTGCCGTCGCAGCAGCCGCCACCGAAGATGGGGGATTTCTACGATCCCGAGCACCCGACCCCTGAagaagaagaaaatgagGCAAAGATTGAAAATGTGCAGAAAACAGGTTTCATCAAAGGACCAGTGTTCAAAGGTGTTGCTTCAAGTCGATTTTTGCCCAAAGGCACGAAGACAAAAGTTAATTTGGAGGAACAGGGACGGCAAAAGGTGTCATTCAGCTTCAGTTTTACAAAGAAAACTTTACAGAATAGATTTCTCACTGCGCTTAGCAATGAAAAGCAAAGTGATTCTCCAAACTCCCCAGCTCCCCCTCTTCAAGTAGACTCAAACCCTAAAGTTAAAATGGACGCTGGAGATACTTTTCCTGCTACAGAAGAATCTTCGCCACCAAAATCGAGAGTGGAATTGGGCAGaattcattttaagaaacatttgcTTCATGTGACATCTAGGCCACAGCTGGCTGCAAGTACAACAGCAGCATCTCCCCTTCCTCCTACAACACAGTTACCAGCAGTCTTAGCAGAGTCGATGATAGACTCACCACCTTcatctccacccccacctcctccacctccccaggcCTCATCACCCTCACCACCAGCACAGATATCAGAGCCAGTGGCCTTGCCGCAACCCCCAGCAACAGCACTAATGACATCACCACCAGGACCTTTACCAGGAGACGTAGCCGTGAGAGCTCAGAAAGAATCACCAGTTAAAAGTGGACCCGAAGTTTTAGAGGTGGATACAAAGCAAGATATTGTATCTAATAGTTTGGAAGAACACACAGTTCAAACTTTGAAGGAACAAGCAGATCATCTCCTGCAAAAAGAAGATTCCCatattgggaaggaagaagaggtttCAGATGGCTCTAAGATAAGCCTCAGTTCTAAAAAAGCAAGTTCTAAGAAGAAATCTTCACAATTTGAAGGCACATTTCTTGGTTCAGAGTCTGATGAAGATTCTGTACGGACTTCTTCCAGTCAAAGATCACATGATTTAAAATCTTCAACAAGCATTGACAAGGAAAGAGATTTTAAGAAGAGCTCAGCACCTTCAAAAAGTGAGGATTTGGGGAAATCATCAAGATCgaaaacagagagagatgatagatattGTAGCTACTCAAAACTTGAACGAGATACTCGGTATGTATCTTCCCGATGTCGGTCCGAAAGAGATCGAAGGCGAAGCCGATCTCGTTCTAGATCTGACAGAGCCTCTAGAACTAGTTTGTCTTATTCTCGCTCAGAAAGATCTCATTATTATGATTCTGAACGGCGCTACCATAGGAGTTCCCCTTATCGTGAGAGGACACGCTATTCTCGGCCATATACTGATAACAGGGCACGGGAGAGCTCAGACTCTGAAGATGAGTATAAGAAGACATACCCACGGCGTACCTCAGCCCATTCCTACAGAGACCTAAGGACATCATCATCTTACTCTAAATTTGATCGGGACTGTAAAACTGAGACCTCTTACTTagagatggagagaagaggaaagtatACTTCAAAACTAGAAAGAGAATCCAAACGGACTTCAGAGCATGAAACCATAAAAAGATGTTGTTCTCCCCCAAATGAACTGGGATTCCGACGGGGGTCATCATATTCCAAGCATGATAACAGTACTTCCCGTTATAAATCTGCCCTTTCAAAATCTATATCCAAGaatgataaatttaaaaattctttctgtTGTACAGAattaaatgaggaaaacaaacaaTCTCATTCGTTTAGTTTGCAGACTCCTTGTTCAAAAGGTAGTGAATTAAGAACAATTAATAAGATTTCTGAAAGAGAAAAGACTGGGTCTCCAACTCCATCAAATCAATTAAACGATTCACCTACTTTTAAAAAGCTAGATGAATCTCCTGTTCTTAAGCCTGAATTTATAGGACACGATGGCCGTGAAAGTATTAAAGAATTGGAGTTATCAAAAGTGAAAAATGATCAATTAAGAAATTTTTGTTCCATTGAATTAAATGTAAACGGATCTCCAGAGACAGAAGCTGATGTGGCAACATTTTGTACTTCTAAGACAGATGCTATATCAATGACTTCTGATGATAGTGTGACTGGATCAGAGGTATCCCCTTTGATCAAGGCTTGCATGCTTTCATCAAATGGATTTCAGAATGTTGgtagatgcagagaaagggaCTCAGATGATACTTGTAGGCAGCATAATACGTCAAAAAGTCCATTTAGGGAAATGGAACCTTTGTTGTCACCACACCATGATAAACTCATGTCTTTGCCAGTTAAGACTATAGATTATCCCAAAACATTAATTAAAGAACCAGTTGATAAGAGACATTCTTGCTGCAAAACCAAAGATTCAGATATATACTGTTCTCCAAATGAAAACCCTGAAGCTGAGAACGCTGAACCTTCAGCTATGACGATTTCTTCACATAGCTTTGTGAATGTGCATTTGGAATCCAAGACAGTTATATGTGATAATAGGGAGCCGACAGACCGGCACTCAGAGAATACATGTGATGAATATAAGCAGAGCATTGGTAGCACTAGTTCAGCTTCTCATAACCATTTTGATGGTTTGTATGAGCCTATAGGGAGTTCAGGTATTTCATCTCTCCAGAGTCCTCCGTCAGGAATAAGATGTGAAGAAAACACATCTCCAACTCTAGATGCAGTGGAGAGTAAAAAAGGCATAGATTTTTTAAAGTATGCACGGAAAGAAACAGATGTTGGTAGTGCCCTTCCTGATTCAGGAAAAGGATTTTCTTGGGAAAACAGGCATAATAATGTGTTATCTGGGCAGTCTTTGCAAGAGGCTCAAGAAGAAGGGAATTCCATATTGCATGAGAGAAGAGGAAGACCAGAAATCCCCTTAGATGAGGAACAAAGAGGCCATACACATATTTCTGATGATTCAGAAGTGGTATTTCCTTATGATTTGAACTTGACCATGGAAGACAGTGATGGTATAACCTACACCTTAAAATGTGATAGTAGTGGAAATGCTCCAGAGATTGTATCTACTGTCCATGAAGACTATTCTGGATCTTCTGCAAGTTCAAGCGATGAAAGTGATTCTGAAGATACAGAGTCTGATGATAGCAGTATTCCAAGAAACCGACTCCAGTCTGTTGTGGTTGTGCCAAAGAATTCTACTTTGCCCATGGAAGAGACAAGTCCCTGTTCTTCTCGGAGCAGTCAGAGCTACAAACATTATTCTGACCGCTGGGAAGATGGATTAGAGACCAGGAGACATGCATATGAGGAAGAGTATGAGAGTAAAGGCTGTTCTCAAACTGAAAAATACTTCCTTCATAAAGGAACAGAGAGAAGTGCAGAAAGTTGTTATTCACAGTTTGGCAGGAAAGCAGATAATCACCTGCCTGACATTGCTCATGCTCAGAGTGACGGGGTTGATAGTACAAGTCAGACAGACTCGAGATCTGACCATCTAGGTCACCTGAATCCAGAGGACACATTAAGAGCCAAAACATCTAGGCCACAAGAGCTACCAGTTTATTCTGACGATTTTGAAGATCTCCCAAATAAGTCTCGGCAGCAGATGATTTTCTCTAATCGGCCAGATAGTAGTAGACTAGGAAAAACAGAGCTGAGTTTTTCTTCCTCTTGTGACATTTCCCGAATGGATGGCTTGCACTCATCAGAAGAGCTCAGAAACCTAGGGTGGGACTTTTCCCAACAGGAAAGGCCCACCACCACATACCAGCAGCCTGACAGCAGCTATGGAACCTGTGGTACACATAAGTATCAACAAAGTACTGAACACTATGGTGGGACCCATAATTACTGGCAAGGCAATGGCTATTGGGATCCAAGATCAGCAGGTAGACCTCCAGGAACTGGGCTTGCTTATGATCGAATCCAAGGGCAAGTACCAGATTCTCTAACAGACGATCGTGAAGAAGAGGAACATTGGGATCAACGAAGTGGATCACATTTTTCAAGCCCGTCCAATAAATTTTTCTTCCATCAGAAGGACAAGGGATCAGTGCAAGCACCGGAAATAAGCAGCAATTCAATTAAAGACGCTTTAGTTATGAACGAAAGGAAAGATTTTTCgaaaaactttgaaaaaaatgatataaaagaGAGAGGGCCTCCTAAAAAACGAAGGCAAGAGTTGGAGAGTGATTCTGAAAGTGATGGTGAACTACAGGCTAGAAAGAAAGTTAGAGTGGAGATGGAGCAGGGAGAATCATCTGTgccccagcactcagaactgaTGGGGCCTTCGTGTGCTATGGATGACTTCAGGGACCCACAGCGGTGGAAAGAATTTGCCAAGCTGGGGAAGATGCCATGTTACTTTGATCTTattgaagaaaatgtttatttaacaGAAAGgaagaagaacaaatcCCACCGGGATATTAAGCGAATGCAGTGTGAGTGTACACCTCTTTCTAAGGATGAAAGAGCTCAAGGTGAAGTAGCATGTGGAGAAGATTGCCTTAATCGTCTCCTCATGATTGAATGTTCCTCTCGATGTCCAAATGGAGATTACTGTTCAAACAGACGGTTTCAGAGAAAACAGCATGCAGATGTAGAAGTCATACTTACAGAAAAGAAAGGCTGGGGCTTAAGGGCTGCTAAGGATCTTCCTTCgaACACCTTTGTCCTGGAATACTGTGGAGAGGTACTTGATCATAAAGAGTTTAAAGCTCGGGTGAAAGAATATGCACGGAACAAAAACATCCACTACTACTTCATGGCCCTGAAAAATGACGAGataatagaTGCCACTCAAAAAGGGAATTGCTCTCGTTTCATGAATCATAGCTGTGAACCAAACTGTGAAACCCAGAAATGGACTGTGAATGGACAGCTGAGGGTTGGATTTTTTACCACCAAACTAGTTCCTTCAGGCTCAGAATTAACTTTTGACTACCAGTTCCAAAGATATGGCAAAGAAGCTCAGAAGTGTTTCTGTGGGTCAGCCAACTGCCGGGGCTACTTGGGAGGAGAAAACAGAGTCAGTATCAGAGCTGCAGGAGGGAAGATGAAAAAGGAACGCTCTCGAAAGAAGGATTCAGTGGATGGAGAACTTGAAGCACTGATGGAAAATGGTGAAGGCCTCTCTGATAAGAACCAGGTTCTTAGTTTATCCCGGCTCATGGTTAGAATTGAAACTTTGGAACAGAAACTTACCTGTCTTAAGCTCATTCAGaacacacactcacagtcctGCCTCAAGTCATTTCTGGAACGTCATGGGTTGTCACTGTTGTGGATCTGGATGGCAGAGCTTGGCGACGGCCGGGAAAGTAACCAGAAGCTTCAGGAAGAGATTATAAAGACTTTGGAGCATTTGCCCATTCCTACTAAAAATATGTTGGAAGAAAGCAAAGTACTTCCAATTATTCAGCGCTGGTCTCAAACTAAGACTGCTGTTCCTCAGTTAAGTGAAGGAGACGGGTATTCTAGTGAGAATACATCACGTGCTCACACACCGCTTAATACACCGGACCCTTCTGCCAAGCCGAGCACGGAAATGGATACAGATACTCCCAAGAAACTCATATTCCGCAGACTGAAGATTATAAGTGAAAATAGCATGGACAGTGCAGTCTCGGACGTCACTAGTGAGCTAGAATGCAAGGATGGCAAAGAGGACCTTGATCAGTTAGAGACTGTCACTGTGGAAGAGGATGAAGAGCTGCAGTCCCAGCAGCTCCTCCCACAGCAGCTGTGCGAGTCCAAAGTTGAGAGTGAAGCCACTATTGAAGTCAGTAAGTTACCCACATCTGAACCGGAGGCAGACACGGAGACAGAGCCCAAAGACAGCAATGGCACAAAACTAGAAGAAACTATTGCTGAGGAAACACCATCCCAAGATGAAGAAGAGGGAGTGTCTGATGTTGAAAGTGAGAGAAGCCAGGAGCCACCAGATAAAACAGTGGATATAAGTGATTTGGCTACCAAGTTACTAGACAGTTGGAAAGATCTAAAGgAGGTGTATCGGATTCCAAAGAAAAGTCAAACTGAAAAGGAGAGCACAGTAGCTGAACGAGGAAGAGATGCTGCTGCCTTCAGAGATCAAACAGCTCCAAAGACTCCTAACAGGTctagagagagagacccagacaagcagtctcaaaataaagagaaaaggaaacgaCGGGGCTCTCTGTCACCACCCTCTTCTGCATATGAGCGGGGAACAAAAAGGCCAGATGACAGatATGATACACCAACTTCTAAAAAGAAAGTACGAATTAAAGACCGAAACAAACTTTCTACAGAGGAGCGCAGGAAGTTGTTTGAACAAGAGGTGGCACAGAGGGAAGCTCAGAAGCAACAGCAACAGATGCAGAACTTGGGGATGACATCACCACTCCCCTTTGACTCTCTGGGATATAATGCCTCTCATCACCCCTTTGCTGGGTACCCACCAGGTTACCCCATGCAAGCCTATGTGGATCCCAGCAACCCTAATGCTGGAAAGGTGCTTCTGCCCACACCTAGCATGGACCCTGTGTGCTCCCCTGCTCCTTATGATCACGCTCAGCCCTTGGTAGGACATTCTACAGAATCCCTTGCTGCTCCCCCATCTGTGCCAGTGGTGCCGCATGTGGCAGCCTCTGTGGAAGTTTCCAGTTCTCAGTATGTAGCTCAGAATGAAAGTGTTGTACACCAAGACTCCAATGTTCCTGTAATGCCAGTACAAGCTCCAGGCCCAGTCCAAGGACAGAATTACAATGTCTGGGAGTCAAACCAACAGTCTGTCAGTGTACAACAGCAGTATTCTCCTGCACAATCTCAAACAACCATATATTATCAAGGACAGACATGTTCAACTGTCTATAGTGTGACCTCGCCTTATTCACAGACAACTCCTCCAATTGTGCAGAGTTATGCCCAGCCAAGTCTTCAGTATATCCAGGGACAGCAGATTTTCACAGCTCACCCACAAGGAGTGGTGGTACAGCCAACTGCAGCCGTGACTTCAATAGTTGCACCAGGGCAGCCTCAGTCCTTACAGCCAccTGAAATGGTTGTAACAAATAATCTACTGGACCTGCCACCACCCTCCCCTCCAAAACCAAAAACGATTGTTTTACCTCCCAACTGGAAGACAGCCCGAGACCCTGAGGGGAAGATCTACTACTACCACGTGATCACAAGACAGACTCAGTGGGATCCTCCTACTTGGGAAAGCCCAGGAGATGATGCCAGCCTTGAGCATGAAGCTGAAATGGACCTGGGAACCCCAACCTATGATGAAAACCCCATGAAGACATCAAAAAAGCCCAAGACAGCAGAAGCAGACACCTCCAGTGAGCtggcaaagaaaagcaaagaagtaTTCAGAAAAGAGATGTCTCAGTTCATTGTCCAGTGCCTGAATCCTTACCGGAAACCTGACTGCAAGGTGGGCAGGATCACCACCACTGAAGATTTCAAGCACCTCGCCCGAAAGCTGACTCATGGAGTTATGAATAAGGAGCTGAAGTACTGTAAGAACCCCGAGGACCTGGAGTGCAATGAGAATGTGAAACACAAAACCAAGGAGTACATCAAGAAGTACATGCAGAAGTTTGGGGCTGTTTACAAACCTAAAGAGGACACTGAACTAGAGTGACCTCAGGCCAGAGTGGAGTATGAGCGGAAAGGATGAATCCTGTGGCTTCTGCCCTACCCCACGGCCAAGGCTGTGCTACTGATGTGATGACCCACCATCCTGAGCAGTTCAAACCTGCAGGTGTCAGCTGTAAGCTGCAAAAGTGAGCTCTGTCTCCAAATGACCCCTAGTTGTGAGCTGTTGGTGTAACAGTTACAGGCCATCAGAGGCAGTAGCCTAGGGAAGACCTTGGCCACACGACCCCATTCTCAAATCTGGGTCTCCCCCTTGGCGGTGCTGTCAGCGCACAGACCCATGCGCACCTCCCCCAGATCCTTTACCCTGacaatatgtattatattttaatgtatatgtgaagatattgaaaataatttgtttttcctggtttttgttctgtttttgtttgctgtTAGCATCTATGTGCTGGAATCAAGGAAAGACTTTGTGAGGATAGTATAAATTCTCCTGCAAGGTTGGATTTGTTATCATGTAAATATCCCAACGCAGGCTGCCTTGTGGTTTGGCCGCCTTGTGCTATGTTGATAAGATTGATTTACTGCTTCAGATCACTTTACTTTATCCAATTTTTACTGAACTttttatgtaaaaaataaaatcaattaaagAACTTGGAATGTGTGCTCCCTCAAAATT