Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Dhfr
Plot displaying the genomic locations of a parental gene (in chr2) and its retrocopy(ies). Each line represents a retrocopy.
Specie Rattus norvegicus
Full Name dihydrofolate reductase
Also known as Dhfr1
Coordinate chr2:21931887-21958927
Strand +
Gene summary Enables NADP binding activity; dihydrofolate reductase activity; and dihydrofolic acid binding activity. Involved in several processes, including axon regeneration; folic acid-containing compound metabolic process; and response to methotrexate. Located in mitochondrion. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to several human genes including DHFR2 (dihydrofolate reductase 2) and DHFRP1 (dihydrofolate reductase pseudogene 1). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Dhfr

Retroname Coord Strand Genomic Region ENSG
DhfrP1 chr4:3087118-3087820 - Intergenic
 N/A UCSC
DhfrP2 chr8:32703954-32704121 - Intergenic
 N/A UCSC

Expression

Transcript Sequences

>NM_130400.2
CCTTAGTGGTACTCAGCTCCAGGCTGCGATTTCGCGCCAAACTTGACGGCACTCTAAGCTGGTGGGGTCTGATCGCCGCTGCAGACATGGTTCGTCCGCTGAACTGCATCGTCGCCGTGTCCCAAAATATGGGCATTGGCAAGAACGGAGACTTACCCTGGCCTCTGCTCAGGAATGAGTTCAAGTACTTCCAGAGAATGACCACAACCTCTTCAGTAGAAGGTAAACAGAATCTGGTGATTATGGGTAGGAAAACCTGGTTCTCCATTCCTGAGAAGAATCGACCTTTAAAGGACAGAATTAATATAGTTCTCAGTAGAGAACTCAAGGAACCACCACAAGGAGCTCATTTTCTTGCCAAAAGTCTGGATGATGCCTTAAAACTTATTGAACAACCAGAGCTAGCAAGTAAAGTGGACATGGTCTGGGTAGTCGGAGGCAGCTCTGTCTACCAGGAAGCCATGAATCAGCCAGGCCACCTCAGACTCTTTGTGACAAGGATCATGCAGGAGTTTGAAAGTGACACATTCTTCCCAGAAATTGATTTGGAGAAATATAAACTTCTCCCAGAATACCCAGGCGTCCTCTCTGAGATCCAGGAGGAAAAAGGCATCAAGTACAAGTTTGAAGTCTATGAAAAGAAAGACTAACATGAAGATGCTCCCAAGTCCTACTGCTTCTCCTAAAAGGATGCATTTTATAAGACCACTTCTGCTGGCTTGCAATCTATGAGTAATTATTTCTTTAGGGAGGGGTGGCT