Summary

Gene Name	Raf1
Specie	Rattus norvegicus
Full Name	Raf-1 proto-oncogene, serine/threonine kinase
Also known as	-
Coordinate	chr4:147532040-147592769
Strand	-
Gene summary	Enables several functions, including ATP binding activity; adenylate cyclase activator activity; and enzyme binding activity. Involved in several processes, including MAPK cascade; protein phosphorylation; and response to hypoxia. Located in cytoplasm and plasma membrane. Biomarker of pancreatic carcinoma. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Raf1

Retroname	Coord	Strand	Genomic Region	ENSG
Raf1P1	chr6:14932161-14933341	+	Intragenic	N/A	UCSC

Expression

Transcript Sequences

>NM_012639.2

GCTTGTTCCGCCATCTTAGATGGCGGGAGTTAGAACGGAGCGAGCTTGAAGCAGGAAGGCTTCTCTGCCGTTCTCCGCAGGCCCTCAGACGGGCCAGCTGGCCGAGCTTTGGGGCGCGTGCCCTGAGGCGCGGGGCGCTAGTGCAGCGATGCGGGGCCTTCCTGGGGCCCCGTCCCCCGGGCTGGGGACACGCCGAATGTAACCGCAACCCGTTCTCTCAACCACCGCTGTCGCTGCACTACGGGACCCGGTGCTGCCCGGCTCCCTCAGGTATAAGTATTGTTGAAATTGCATCAATGGAGCACATACAGGGAGCTTGGAAGACGATCAGCAATGGTTTCGGACTCAAAGATGCTGTGTTTGATGGCTCCAGTTGCATCTCCCCTACAATTGTTCAGCAGTTTGGCTATCAGCGTCGGGCCTCTGATGATGGCAAACTCACGGATTCTTCTAAGACAAGCAATACTATCCGGGTTTTCTTGCCGAATAAGCAAAGGACTGTGGTCAATGTGCGGAATGGGATGAGCTTGCACGACTGCCTTATGAAAGCTCTGAAGGTTAGAGGCCTGCAGCCAGAGTGCTGTGCAGTGTTCAGACTTCTTCAGGAGCACAAAGGTAAGAAAGCACGCTTAGATTGGAACACCGACGCCGCCTCTCTGATTGGAGAAGAACTGCAAGTGGATTTTTTGGATCACGTTCCACTCACAACTCACAACTTTGCTCGGAAAACGTTCCTGAAGCTTGCATTCTGTGACATCTGTCAAAAGTTCCTGCTAAATGGATTTCGATGTCAGACTTGTGGCTACAAGTTTCATGAGCACTGTAGCACCAAAGTACCTACTATGTGTGTGGACTGGAGTAATATCAGACAGCTCTTGCTGTTTCCAAATTCCACTGCAAGTGACAGTGGAGTCCCAGCACCACCCTCTTTCACAATGCGTCGGATGCGAGAATCTGTTTCCCGGATGCCTGCTAGTTCCCAGCACAGATACTCCACACCCCATGCCTTCACTTTCAACACCTCCAGCCCTTCCTCTGAAGGTTCCCTGTCCCAGAGGCAGAGGTCAACGTCCACTCCCAATGTCCACATGGTCAGCACCACCCTGCCTGTGGACAGCAGGATGATTGAGGATGCAATTCGAAGTCACAGTGAATCAGCCTCACCTTCAGCCCTGTCCAGCAGCCCCAACAACCTGAGCCCAACAGGCTGGTCACAGCCCAAAACCCCTGTGCCAGCACAAAGAGAGAGGGCGCCAGGATCTGGGACCCAGGAAAAAAACAAAATTAGGCCTCGTGGGCAGAGAGATTCAAGTTATTACTGGGAAATAGAAGCCAGTGAGGTGATGCTGTCTACTCGGATTGGCTCGGGCTCCTTTGGCACTGTGTACAAGGGCAAGTGGCATGGAGATGTTGCAGTAAAGATCCTAAAGGTGGTTGACCCAACTCCAGAGCAACTTCAGGCCTTCAGGAACGAGGTGGCTGTTTTGCGCAAAACACGGCATGTTAATATCCTGCTGTTCATGGGGTACATGACAAAGGACAACCTGGCGATTGTGACCCAGTGGTGTGAAGGCAGCAGTCTCTACAAACACCTGCATGTCCAGGAGACCAAATTCCAGATGTTCCAGCTAATTGACATTGCCCGGCAGACAGCTCAGGGAATGGACTATTTACATGCAAAGAACATCATCCACAGAGACATGAAATCCAACAATATATTTCTCCATGAAGGCCTCACGGTGAAAATCGGAGATTTTGGTTTGGCAACAGTGAAGTCGCGCTGGAGTGGTTCTCAGCAGGTTGAACAGCCCACTGGCTCTGTGCTGTGGATGGCCCCAGAAGTAATCCGAATGCAGGATAACAACCCGTTCAGCTTCCAGTCCGATGTCTACTCCTATGGCATTGTGCTGTATGAGCTGATGACTGGGGAGCTTCCCTACTCCCACATCAACAACCGAGACCAGATCATCTTCATGGTGGGCCGTGGGTACGCCTCCCCAGATCTTAGCAGGCTCTACAAGAACTGCCCCAAGGCAATGAAGAGGTTGGTGGCTGACTGTGTGAAGAAAGTCAAAGAAGAAAGGCCTTTGTTTCCTCAGATCCTGTCTTCCATTGAGCTGCTTCAGCACTCTCTGCCGAAAATCAACAGGAGCGCCTCTGAGCCTTCCCTGCATCGGGCAGCTCACACTGAGGACATCAATGCTTGTACGCTGACCACATCCCCAAGGCTACCAGTCTTCTAGCTGACGTTATAGCTGTTCTTAGGCCACCAGGGGACGAAGAAGAGTCAGCAGGCACCACTTTCTGTTTCCTTGGGGGCAGAATGCATGTTTCCGGAAAAGCTGCTGCTAAGGACCTAGACTACTCACAGGGCCTTAACTTCATATTGCCTTCTTTTCTACCCTTCCTGCCCTGGAAATGGAAGCTGTCCGCCAAGCCAGCCTGTTCCAGAGGTATACAAGTCAGCGAGTATTTTTAGGGCAAATGGCCTTGGAGAGAGAAGGCAGGGCACTCCGGCTACTGCAGGGACATGCAGTTGAGAACTTGGCTCATTGAGCCTGTACAGACAGTGGTGCAGTGCCAGTTTTGCACATGGAGTCCTGGCCACCTGGGGGAGCCTGCTTTGGTACTACAGAACTTCACTTTGTGGACACACCTTCCTCTTACTGAGTCTAAGATGTCCTGTGCAGAGGATGCTTTCCAAGCACGGTGCTCCACCTTCTGGCAGCCTCCCACACGCTGAATCTGTCTTCCAGGAGCTGCCCCTATGGGGTGGGCTGCAGCCCAGCCCTATCTCTATAGTCACATCCTTGTCTGTAAGAAAGCCAGGAATACAGGTTTTCTTAATGATTTTGGGTTTTAATTTTGTTTTTATTGAGCCTGATAAAATACAGTTATCTGATGGTTCCTCAATTATGTTATTTTAATAAAATAAATTAAATTTAGGTTTAA