Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Tp53
Plot displaying the genomic locations of a parental gene (in chr10) and its retrocopy(ies). Each line represents a retrocopy.
Specie Rattus norvegicus
Full Name tumor protein p53
Also known as Trp53|p53
Coordinate chr10:56186299-56198449
Strand +
Gene summary This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it is believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Alternatively spliced transcript variants have been found for this gene, but the biological validity of the variants has not been determined. p53 pseudogenes have been found on chromosomes 9 and 18. [provided by RefSeq, Jul 2008]

Retrocopy(s) from Tp53

Retroname Coord Strand Genomic Region ENSG
Tp53P1 chr2:214924993-214926619 - Intergenic
 N/A UCSC
Tp53P2 chr2:49382417-49383172 - Intergenic
 N/A UCSC
Tp53P4 chr13:14578613-14579921 - Intragenic
 N/A UCSC
Tp53P5 chr14:90823254-90824894 - Intergenic
 N/A UCSC
Tp53P6 chr18:84790292-84791987 - Intergenic
 N/A UCSC
Tp53P3 chr9:27543736-27544593 + Intergenic
 N/A UCSC

Expression

Transcript Sequences

>NM_030989.3
TCTGAAGCTCCAGTTCATTGGGACTTATCCTTGCTATAGGTAGCGACTACAGTTAGGGGGTACCTGGCATCCGGGCCCGCACCCTACTTCCCAGCAGGGTGTCACGCTCCCCTGAAGACTGGATAACTGTCATGGAGGATTCACAGTCGGATATGAGCATCGAGCTCCCTCTGAGTCAGGAGACATTTTCATGCTTATGGAAACTTCTTCCTCCAGATGATATTCTGCCCACCACAGCGACAGGGTCACCTAATTCCATGGAAGATCTGTTCCTGCCCCAGGATGTTGCAGAGTTGTTAGAAGGCCCAGAGGAAGCCCTCCAAGTGTCAGCTCCTGCAGCACAGGAACCTGGAACTGAGGCCCCTGCACCCGTGGCCCCTGCTTCAGCTACACCGTGGCCTCTGTCATCTTCCGTCCCTTCTCAAAAAACTTACCAAGGCAACTATGGCTTCCACCTGGGCTTCCTGCAGTCAGGGACAGCCAAGTCTGTTATGTGCACGTACTCAATTTCCCTCAATAAGCTGTTCTGCCAGCTGGCGAAGACATGCCCTGTGCAGTTGTGGGTCACCTCCACACCTCCACCTGGTACCCGTGTCCGTGCCATGGCCATCTACAAGAAGTCACAACACATGACTGAGGTCGTGAGACGCTGCCCCCACCATGAGCGTTGCTCTGATGGTGACGGCCTGGCTCCTCCCCAACATCTTATCCGGGTGGAAGGAAATCCGTATGCTGAGTATCTGGACGACAGGCAGACTTTTCGGCACAGCGTGGTGGTACCGTATGAGCCACCTGAGGTCGGCTCCGACTATACCACTATCCACTACAAGTACATGTGCAACAGCTCCTGCATGGGGGGCATGAACCGCCGGCCCATCCTTACCATCATCACGCTGGAAGACTCCAGTGGGAATCTTCTGGGACGGGACAGCTTTGAGGTTCGTGTTTGTGCCTGTCCTGGGAGAGACCGTCGGACAGAGGAAGAAAATTTCCGCAAAAAAGAAGAGCATTGCCCGGAGCTGCCCCCAGGGAGTGCAAAGAGAGCACTGCCCACCAGCACAAGCTCCTCTCCCCAGCAAAAGAAAAAACCACTCGATGGAGAATATTTCACCCTTAAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAATTAAAGGATGCCCGTGCTGCCGAGGAGTCAGGAGACAGCAGGGCTCACTCCAGCTACCCGAAGACCAAGAAGGGCCAGTCTACGTCCCGCCATAAAAAACCAATGATCAAGAAAGTGGGGCCTGACTCAGACTGACAGCCTCTGCATCCTGTCCCCATCACCAGCCTCCCCGTCCCCTCCTTTCTTGCCATTTTATGACTTTAGGGCTTGTTATGAGAGCTGACAAGACAATGCTAGTCCCTTCACTGCCTTTTTTTACCTTGTAGATAGTACTCGGCCCCCTCTATGCAAACTGGTTCCTGGCCCAGATTGGGGAATGGGTTGGTAGTTGCTGGGTCTCTGCTGGTCCAGCGAAATCCTATCCGGTCAGTTGTTGGACCTGGCACCTACAGTGAAATTTCACCCCACCCCACCGCCTGTAAGATTCTATCTTGGGCCCTCATACGATCTGTATCCTCCAGGACCCATTTCCTCCACTCTGCAAAGCCTGTCTGCATTTATCCATCCCCCACCCCTCTCCCTCTTTTTATCTCTTTTTATATATCAATTTCTTATTTTACAATAAACTTTTGTTACCACTTGTA
>XM_017597018.1
AACTGCTATCCTCGACATCTTATTTTTCTGGATTACTTGGTTATTGCTTTTGCGAAGGAGGAGGTGTTTATTTAAAAGAGTGCACCGATAGGTCGTTTCTTCGTGCCGGAAAAGCAAATTACCGAGTATCCGGTTTTGGGATAACTGTCATGGAGGATTCACAGTCGGATATGAGCATCGAGCTCCCTCTGAGTCAGGAGACATTTTCATGCTTATGGAAACTTCTTCCTCCAGATGATATTCTGCCCACCACAGCGACAGGGTCACCTAATTCCATGGAAGATCTGTTCCTGCCCCAGGATGTTGCAGAGTTGTTAGAAGGCCCAGAGGAAGCCCTCCAAGTGTCAGCTCCTGCAGCACAGGAACCTGGAACTGAGGCCCCTGCACCCGTGGCCCCTGCTTCAGCTACACCGTGGCCTCTGTCATCTTCCGTCCCTTCTCAAAAAACTTACCAAGGCAACTATGGCTTCCACCTGGGCTTCCTGCAGTCAGGGACAGCCAAGTCTGTTATGTGCACGTACTCAATTTCCCTCAATAAGCTGTTCTGCCAGCTGGCGAAGACATGCCCTGTGCAGTTGTGGGTCACCTCCACACCTCCACCTGGTACCCGTGTCCGTGCCATGGCCATCTACAAGAAGTCACAACACATGACTGAGGTCGTGAGACGCTGCCCCCACCATGAGCGTTGCTCTGATGGTGACGGCCTGGCTCCTCCCCAACATCTTATCCGGGTGGAAGGAAATCCGTATGCTGAGTATCTGGACGACAGGCAGACTTTTCGGCACAGCGTGGTGGTACCGTATGAGCCACCTGAGGTCGGCTCCGACTATACCACTATCCACTACAAGTACATGTGCAACAGCTCCTGCATGGGGGGCATGAACCGCCGGCCCATCCTTACCATCATCACGCTGGAAGACTCCAGTGGGAATCTTCTGGGACGGGACAGCTTTGAGGTTCGTGTTTGTGCCTGTCCTGGGAGAGACCGTCGGACAGAGGAAGAAAATTTCCGCAAAAAAGAAGAGCATTGCCCGGAGCTGCCCCCAGGGAGTGCAAAGAGAGCACTGCCCACCAGCACAAGCTCCTCTCCCCAGCAAAAGAAAAAACCACTCGATGGAGAATATTTCACCCTTAAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAATTAAAGGATGCCCGTGCTGCCGAGGAGTCAGGAGACAGCAGGGCTCACTCCAGCCTCCAGCCTAGAACCTTCCAAGCCTTGATCAAGAAGGAAAGCCCAAACTGCTAGCTCCCATCACTTCATCCCTCCCTTTTCTGTCTTC