Summary

Gene Name	GABPA
Specie	Homo sapiens
Full Name	GA binding protein transcription factor subunit alpha
Also known as	E4TF1-60|E4TF1A|NFT2|NRF2|NRF2A|RCH04A07
Coordinate	chr21:25734972-25772460
Strand	+
Gene summary	This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]

Retrocopy(s) from GABPA

Retroname	Coord	Strand	Genomic Region	ENSG
GABPAP	chr7:63893072-63897908	+	Intergenic	ENSG00000235720	UCSC

Expression

Transcript Sequences

>NM_002040.4

AGTCGGTCGACGCTCACCGGACAGGAAGCGTCTCGGAGACAGTCTGCGACCGGACGGGTCTAGGTGAGACAGAAGCCAAACAGGAGGAGGAAGTGGAGGGTAAGTGCTTCCGGGTCCCCTGGCACAGCCTCCGCCATCTTTTCTTCGCCTAATTTGACCCGTTCTTTTTCCCCTCCTTGAAACCTTGCTCTGTACGCATGCGCTCTTTGAGTGGCCTTTCCCCTAGTTCAAGCTCCCCTCCGAGTCAGCGTCCTGTTCGTTAGGGTTATCGAAGTGTATAAAGGTGCAGGGAAAGTGAGACTGTGTAAAACAAAGCGGATTGGGGCGTTGTGCTTCCTTGTACCTCGTGAGCCTCCGTTGCCTTGGGCGGTCGTTTTGCGCACCCTGCCGGGAGTTGTAGTCCTGGACCCGAAGGTGCCTGGGAGGCGGGAGGGGGGTTGGGGCTTCTCAGCGCCGATTCCGCGGGAAGGGCCCTGGGACCTCACACTTCTAGTCGCGGGAGCTGCAGGTCTTACCCGGAGAGACGCTGCACGTGGAGCCCTCGCCGCTGCCGTTCTCAGCCGGCTCTGGAGTGCGGGCGGGGGCGACAGGGCCGATTCCGGAGTGGGACTGATCCTTTGAAATACTCCAGCCATGACTAAAAGAGAAGCAGAGGAGCTGATAGAAATTGAGATTGATGGAACAGAGAAAGCAGAGTGCACAGAAGAAAGCATTGTAGAACAAACCTACGCGCCAGCTGAATGTGTAAGCCAGGCCATAGACATCAATGAACCAATAGGCAATTTAAAGAAACTGCTAGAACCAAGACTACAGTGTTCTTTGGATGCTCATGAAATTTGTCTGCAAGATATCCAGCTGGATCCAGAACGAAGTTTATTTGACCAAGGAGTAAAAACAGATGGAACTGTACAGCTTAGTGTACAGGTAATTTCTTACCAAGGAATTGAACCAAAGTTAAACATCCTTGAAATTGTTAAACCTGCGGACACTGTTGAGGTTGTTATTGATCCAGATGCCCACCATGCTGAATCAGAAGCACATCTTGTTGAAGAAGCTCAAGTGATAACTCTTGATGGCACAAAACACATCACAACCATTTCAGATGAAACTTCAGAACAAGTGACAAGATGGGCTGCTGCACTGGAAGGCTATAGGAAAGAACAAGAACGCCTTGGGATACCCTATGATCCCATACAGTGGTCCACAGACCAAGTCCTGCATTGGGTGGTTTGGGTAATGAAGGAATTCAGCATGACCGATATAGACCTCACCACACTCAACATTTCGGGGAGAGAATTATGTAGTCTCAACCAAGAAGATTTTTTTCAGCGGGTTCCTCGGGGAGAAATTCTCTGGAGTCATCTGGAACTTCTCCGAAAATATGTATTGGCAAGTCAAGAACAACAGATGAATGAAATAGTTACAATTGATCAACCTGTGCAAATTATTCCAGCATCAGTGCAATCTGCTACACCTACTACCATTAAAGTTATAAATAGTAGTGCGAAAGCAGCCAAAGTACAAAGAGCGCCGAGGATTTCAGGAGAAGATAGAAGCTCACCTGGGAACAGAACAGGAAACAATGGCCAAATCCAACTATGGCAGTTTTTGCTAGAACTTCTTACTGATAAGGACGCTCGAGACTGCATTTCTTGGGTTGGTGATGAAGGTGAATTTAAGCTAAATCAGCCTGAACTGGTTGCACAGAAATGGGGACAGCGTAAAAATAAGCCTACGATGAACTATGAGAAACTCAGTCGTGCATTAAGATATTATTACGATGGGGACATGATTTGTAAAGTTCAAGGCAAGAGATTTGTGTACAAGTTTGTCTGTGACTTGAAGACTCTTATTGGATACAGTGCAGCGGAGTTGAACCGTTTGGTCACAGAATGTGAACAGAAGAAACTTGCAAAGATGCAGCTCCATGGAATTGCCCAGCCAGTCACAGCAGTAGCTCTGGCTACTGCTTCTCTGCAAACGGAAAAGGATAATTGAGCCCCAGGACATTCTGAGACTCCAAAGTCTTTCTTAAAATGTTTAGAGCAAGTATAGCTCTTACCTTTATTACTGAATTTGAATCTTCTTTTATTTCTAGGCTGTACAGTCTGATGCATGATTTTTTTATAAATATTTCATACTCTTGTGAATTTGGATCTTTTTACTTTGAGCATATATTTTAGAATATGTGTATGTTAAAGGATCTCCACAATGTCTGCAGTGTGAAGGCAGGTTCATTGTGGAATAGTTTAACAGTCAGGAAGGCTAAACTGGTCAGTATTAATGTGTAGCCCTACCAAAAATAGCCAGTAGTATCTGAAAATGAAAAATAAATGAAGTATCTCTAGGAAACAGTCTGGCTTAACTATTTTTGAAAATATAACTGTTTCCCCTCTCTGCTGCTTTAGATGTTGCTTTACATAGAACCAGAAAATGGAATTTCTCAGCTAAAGCATGTGTGCCTGTTTCATCTAATCAAGCAGAGCTAAAATGTTCATACCGAATAAATTTATATTAATAAATTACTAAACTAAGAGTATCAGGTTATTTATATATTTGCAAGCAAAGGACAGTAAGAAGTTGACTGGCAAAAGAGCAGTGCTGAAGGAGGAGATCCAGGTTTAAATCTGGCTTATTAACTCAAGCCAATTTTAAGGATTTTCTGTATAGATTACTCATGTCAGACCAAGAATTTAAATTATTTTGAGAGAGGCATTTAATTCTAATAAACCAGCTGTTATAAAAATTATAAAATGATCTCTGTTTTTCCTGTCAGAGATTTAAAAAACTGAAAAGGTATACCTCAACCCAAAAATAAAGGTTTGTTTTGGTTTGTTATGGCTTCCTTTTTTAAAAAATTACCCTGTAGTGCCAGTTTATTATGCAAAGCAGCTTATATTCCTTTGTTTCTGATAAAATGAAGACTTTAAATCAGTCAGTAGTACTTTACCTTTCAAGGCATTAGTAAATTACTTGCAAATAGTTTTAAAAGGAAAATACGACCTTTGTTATAGGCAGTCTTCTCTTTAAGACAATACTTTTCCACTTGTTTTCCTTTTCCATATTATATATGTGTATTCATATAGCTGTATACATATTCAGTTGATCATTTTATAAACATATGAAGGCATAAAGATATACAGAAGAAAAATTATTAAACAACTCATTTTAAGATTCAAATTAACTAATTCCTGCATATATGACATTCCTTACATAAGCGAACACTAAACAAAAATGGCTAGAAATGTCTTTTTCTTTCTTTTCTCTCTTTGTTGTTTAAGGTATTAAGCACGAATTATTACATGAGACTGGCAGATAGCTATTAATCCTCTTACAGATTTGAGAAAGTTGATTCTCAAATATTTATGCACCTTCTCCTTCATTGTTTTCTTTAAATCTGTCCTCTTAAAAAGCTTCTTAAGAGCTCAGTTAATGCTTTTGACTTAACTAGGAGAAAAAGGCATGATAATACAGGCAAGATGGCATTGTTAGCAATTCTGGTAGTGGTTTGGAATGAATCCTAAGAGGCAGGGATCTTAAGGACAAGGAAGAGAAGAGAGAGAGGGAGGGATCTTTGATCTCTTTCTCTGGTAATCTTAATGCATAATTTTACTAAAACATGTTCTCAATTCATTCATATTATTAAGCTCTTCCTGCAGTTGATATCTGAGCAGAGTAAGATTTGTATTTCCATTTTTACTTTTTTGAAAGAGAATATATGGACAGATTATTAGTACAATTTGGGCACTGTGGTTTTAAGAATATCTGAGTAAAATAACAATATGAAATAATAAACAGAAGCTCTAACGTCAGGTAACAAATAGACAGCAAGAAAGGTTTTGCACCATCCTCTTACGGCCTAGAGAGTTGACAAGTTGCTTGTAGTTTTAAAAAAATAATAAAGTATACCCTTCTGGTATATCATCAAGAGCTTAAGAATCTTGGCTTTCATATTTAAAATGCTTTTGGGGAGACATATATTAAAATTTTAGCCAAGATGATAGACATGTCTCAATTATATATGTGTGTGTATGTTTTTAAAGCTAAAAACATTACTTTTAGATCCCTAGAATGAAAATTTTTTTCTCATCTATGCAATTCCCATATGGTTTTTTTTTAAATCATATTTTATTCATTTTCTCCCTTTAGCAATTTTCATTTTATTTCTCATAATTTGAACAGAGACAGTTCTCATACATGATCAGATGCTTTTTTTTTCTTCTTACCATCATTTATGCATGACATAGGTAATGTGACTAATTTCTCCAGTTGATTCAAGAAACTCATTACTTTGCCTCAAATTATATGTAAAATATTTGTTTTACTTAGGTTACAGTTATCAGAAAGGTAGTTTTTTTCTTCTATTAAAATATAACATTGTGAAAGAAAATAAAATTTATGCTATTCTTTGCTTTGTTTTTATAAATGAATTTTTCATAGAATTTACAGTATATTCAAAGGAAGAAAGATAAAATTATTGGTCATCATTTGTACCTTAGAAGTACAAGAATTTAAGTAAAAGAAATGTTCATTTTTGTTTTAAAATTTGTTTTCCATGTGAAGTTTTTATTGAGCCAACTTTCATACATATCTTGCTAGCCTAAAGTCTAAATATTTGTGTTGGCATCAGAAAAACAAATGAGGCAGAATTGCTATGTGTGGTTGATCTTCAGATAAATTGACTGATCACAGTTATTTTTGTATCAGTCTATGTTATTAGGAAAAATTGTTTAGTTGTTTTCTCCCCTGATTAATGGTGATATTCAAGTATGATACAAAAAGAATTGTACCACCAAATATTTTTGTGAGGTCTGCTGTTTTCCATATTCATTTTATGCTACTGCCTTTAAGAAAGAACTAGTGTATCCTTGAAATAGCACAAAAATGTTTTAAAATTCATAATTGCAAAACAAATCTGTGACTAACTTAATGTCTTCAGATCTAAAGGGTGTAAAAATATTGATACTTCAATATTTCACTTGCTGCCAGGAAAAACAAAATTCTCAATCTTTTGTAAATGGGAGGAGGACTTTTGCATACATTTTTACTCTTTAAATAACGACAACGACACTTATACTGTCATAATAACAATTATGTATTTCTTTGTGGTTTTAATTTTTTTTGTAATTTTACATAAAACAGTTATTTTCTATTTTTACGCAGATAAATATTTGTGCATAAAATGTAAAAATAGTAAAATGAGAAAAATAAAACTATTATACAGTA