Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name IBTK
Plot displaying the genomic locations of a parental gene (in chr6) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name inhibitor of Bruton tyrosine kinase
Also known as BTBD26|BTKI
Coordinate chr6:82169987-82247747
Strand -
Gene summary Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Retrocopy(s) from IBTK

Retroname Coord Strand Genomic Region ENSG
IBTKP1 chr18:44039476-44040408 + Intergenic
 ENSG00000267716 UCSC

Expression

Transcript Sequences

>NM_015525.4_2
ATCCCCGTTCCCGATTCCTGTAGTAGCGGCTGTATTGCAGCCGCCTGCCGAACTGACCCGGGTCTGGGGACTGGCCCCTCTGGCGCCGTTCGGTTTCTCTTATTGCCTTCACTGAGGATGAGTCCCTTTGTGGCTCTATGTGGACCCTGCGGAATCCACCGGCGCAGTTTCATCTAGCGACTGGTCACCCTTGCAATTATGGATATTTAAAAGGGTCAGACAGTGTGGAGGGGGAGTTCCCCTCCTCACTCCCCCTTGGTGCTTGACTCCAGGAATAATTTATAAACTGTGGAATTTTTTTAAATGAAGAACTTGTATTTGATATGAACTTTATAGAGCTATTTATAATTTTTTTGATTTAAGTGCCAAAAAATTGTATAAAGATATATAGTTTTATACTATTGTCAGGAGGATTTAAATTATCCTAAAAAGGTAATTTATTCTCTGTAACTTCCTCAATAGCACCTTTGTGTCCTGGCTTTTTCATTTTTTAAAATTAGTTTTCACGATTCTGAAGTAAGTGGTATAAAAACAGTTAGGATGAGTTCACCCATGCCTGACTGCACATCAAAGTGTCGATCCCTGAAGCATGCTTTGGATGTCCTTTCTGTGGTAACAAAGGGGAGCGAAAACCAGATTAAGGCCTTTCTCTCCAGTCATTGTTACAATGCTGCAACTATCAAGGATGTTTTTGGCAGGAATGCCCTCCACCTTGTTTCCTCCTGTGGAAAGAAAGGAGTGTTAGATTGGCTTATTCAGAAAGGAGTGGATCTGTTGGTGAAAGACAAAGAGTCTGGATGGACAGCATTGCACAGAAGCATTTTTTATGGACATATTGATTGTGTTTGGTCTCTATTGAAGCATGGTGTTAGTCTGTATATTCAAGATAAAGAAGGCTTGTCAGCTTTGGATCTTGTAATGAAGGATAGACCAACTCATGTAGTATTCAAGAATACTGATCCTACAGATGTTTATACTTGGGGCGATAATACAAATTTTACCCTGGGTCATGGAAGCCAGAATAGCAAACATCATCCAGAGTTGGTGGATCTGTTCTCCAGGAGTGGGATTTATATCAAGCAGGTGGTGCTTTGTAAATTTCACTCCGTGTTTCTGTCTCAGAAAGGGCAGGTTTATACCTGTGGTCATGGTCCTGGAGGGCGATTAGGACATGGAGATGAACAGACATGCTTGGTCCCTCGGCTTGTGGAAGGACTGAATGGTCATAATTGTTCCCAAGTGGCAGCTGCTAAGGATCATACTGTTGTATTAACTGAAGATGGATGTGTTTATACATTTGGTCTAAACATTTTTCATCAATTAGGAATTATTCCACCGCCTTCCAGTTGTAATGTACCCAGACAGATACAGGCAAAATATCTGAAAGGAAGGACAATCATTGGCGTTGCAGCAGGCAGGTTTCATACAGTCCTATGGACTAGAGAAGCTGTTTACACTATGGGACTAAATGGTGGACAACTGGGTTGTTTGCTAGATCCCAATGGAGAAAAGTGTGTAACTGCTCCTCGTCAGGTCTCTGCCCTTCACCATAAAGACATTGCTCTGTCTTTGGTTGCTGCAAGTGATGGAGCTACAGTCTGTGTTACCACAAGGGGAGATATTTACTTACTTGCAGACTATCAGTGCAAGAAGATGGCTTCTAAACAGTTGAACTTGAAAAAAGTTCTTGTGTCTGGGGGTCATATGGAATACAAGGTTGATCCTGAACATTTGAAAGAAAATGGGGGTCAAAAAATTTGCATTCTTGCAATGGATGGAGCTGGAAGGGTGTTTTGCTGGAGATCAGTCAACAGTTCTCTGAAGCAGTGTCGATGGGCCTATCCACGTCAGGTCTTCATTTCTGATATTGCTTTAAATAGAAATGAAATTCTATTTGTTACGCAAGATGGAGAAGGATTTAGAGGGAGATGGTTTGAAGAGAAAAGAAAGAGTTCTGAAAAGAAAGAGATTTTATCAAACCTTCACAATTCCTCATCAGATGTGTCTTATGTCTCTGATATAAATAGTGTGTATGAAAGAATTCGACTTGAGAAACTTACCTTTGCACATAGAGCTGTTAGTGTCAGCACAGATCCAAGTGGATGCAACTTTGCAATCCTGCAGTCAGATCCTAAAACAAGCCTTTATGAAATTCCAGCTGTGTCCTCATCATCCTTTTTTGAAGAGTTTGGCAAACTGTTGAGGGAAGCAGATGAAATGGACAGCATTCATGATGTGACATTTCAAGTTGGCAATAGACTCTTCCCTGCACATAAATATATTTTGGCAGTGCATTCTGATTTTTTTCAGAAATTGTTTCTTTCAGATGGTAATACTTCAGAATTTACAGATATTTACCAGAAAGATGAAGATTCTGCAGGGTGCCATCTCTTTGTGGTAGAGAAGGTTCATCCTGACATGTTTGAATACCTTTTACAATTTATATACACAGATACTTGTGACTTTTTAACTCATGGCTTCAAACCAAGAATACACTTAAACAAAAACCCAGAAGAATATCAGGGAACTCTGAATTCTCATTTGAATAAAGTGAATTTCCATGAAGATGATAACCAGAAGTCTGCATTTGAAGTTTACAAAAGTAATCAAGCTCAAACAGTTAGTGAGAGGCAGAAGAGCAAACCTAAATCTTGTAAAAAAGGAAAAAATATTAGGGAAGATGATCCTGTAAGAATGTTGCAAACTGTTGCAAAGAAATTCGACTTCAGTAATTTGAGTAGTAGGTTAGATGGAGTCAGATTTGAAAATGAAAAAATTAATGTTATTGCCAAGAACACTGGTAATAAACTGAAGCTAAGTCAGAAAAAATGTTCATTTCTGTGTGACGTGACCATGAAATCAGTGGATGGAAAGGAATTTCCTTGTCATAAATGTGTTCTTTGTGCTAGACTTGAATATTTTCATAGTATGCTGAGTAGCTCATGGATTGAGGCTTCCAGTTGTGCAGCTCTGGAAATGCCAATACATTCTGATATATTAAAAGTTATTTTGGACTACCTCTATACTGATGAAGCTGTGGTGATAAAAGAATCTCAAAATGTAGATTTTATTTGTAGTGTTCTTGTGGTGGCTGATCAACTTCTCATAACCCGGTTGAAAGAGATTTGTGAAGTAGCATTAACTGAAAAACTTACCCTGAAGAATGCTGCTATGCTACTGGAATTTGCAGCAATGTATAGTGCAAAACAGTTGAAACTGTCTTGTTTACAGTTTATAGGATTGAATATGGCAGCTTTACTTGAAGCAAGGTCTCTTGATGTTTTAAGCGATGGTGTTTTGAAGGATCTTTCTGAGTTTTACCGGAAAATGATTCCAGCAATGGATAGAAGAGTCATTACACCATATCAAGATGGACCAGATATTAGCTATTTGGAAGTAGAAGATGGAGATATCTTCTTGAAAGAAGAAATAAATATGGAACAAAATCATTCGGAAACTATGTTCAAGAAAGCAAAAACAAAAGCTAAAAAGAAGCCACGTAAACGTTCAGATAGTTCTGGAGGTTATAACCTTTCAGATATTATTCAGAGTCCATCATCTACAGGATTATTAAAGTCTGGTAAGACCAATTCTGTGGAATCTCTTCCAGAACTGTTGACATCAGACTCTGAAGGAAGCTATGCAGGAGTGGGTAGTCCTAGAGATTTACAGTCCCCTGATTTCACAACAGGATTTCATTCAGATAAGATTGAGGCGAAAGTCAAACCGTATGTTAATGGTACATCTCCTGTGTATTCTAGGGAAGATTTAAAACCATGGGAAAAGTCACCAATACTTAAAATATCTGCTCCACAGCCTATTCCCAGTAACAGAATTGATACTACCAGCTCTGCCAGTTGGGTTGCTGGTTCTTTCAGTCCTGTCAGCCCTCCTGTTGTGGATCTCAGAACTATCATGGAAATAGAAGAAAGTAGACAAAAATGTGGAGCTACACCAAAGTCACATTTAGGCAAAACAGTTTCTCATGGAGTTAAACTTTCTCAGAAGCAACGAAAAATGATTGCATTGACTACCAAGGAAAACAATTCAGGAATGAATAGCATGGAAACAGTTTTATTCACTCCTTCAAAAGCCCCCAAACCAGTGAATGCATGGGCATCTTCTCTGCATTCAGTTTCATCCAAGTCATTCCGGGATTTCTTACTAGAAGAAAAAAAGTCTGTTACTAGCCATAGTTCAGGCGATCATGTCAAAAAAGTTTCTTTTAAAGGAATTGAAAATTCTCAGGCACCAAAAATTGTCAGATGCTCTACCCATGGTACCCCAGGACCAGAAGGCAACCATATTTCAGATTTACCACTTCTAGACAGTCCCAATCCCTGGCTATCTTCTTCAGTGACTGCTCCATCCATGGTAGCCCCAGTCACTTTTGCATCTATTGTAGAAGAAGAACTACAACAAGAAGCAGCTCTTATTAGAAGTCGAGAAAAACCGTTGGCTCTGATTCAGATTGAGGAGCATGCCATACAAGATTTATTGGTTTTCTATGAGGCATTTGGCAACCCTGAAGAGTTTGTCATTGTTGAAAGGACACCGCAGGGACCACTGGCAGTACCTATGTGGAATAAGCATGGATGCTAGTTCACTGTGGAGTTGAGATGCATTTTACATAATTATGAGTTTGTTCATATAAAGAAAAGCTGTGGAAAAGAGTCTTAGAGATTTTGTAATATCATTCTAAATAGATTAAGAAAAGATATAATTTCTTTACTGCAGTTAAATCATATAATGTTTGTATGATTAAAAATAAATTTCTCAGAATTGTGATTTTAGTAACTTTATATAAAATGTGTGAGACAAAAACTTATTAAGGTTAAATAGAATTGTTTCTTCTGAATAATCTAACAAAGGAAAATATAAGTGATTGAATCATAAGATATAAGGGGGGTAAAGTATTAAAAATAACTTTTTTGTTTGATAACTTGAGAATTTAGAAGATTTTGCCAAGTATGTGTTGTTGCTTGACTTCTTAAATATGGCATTGATGAATTTAAAGTAGGAGCATCAGTTATTACTTCTGATTCATTAATGGCCAGAATTTTGTGTTTGGTGTAATAGTTGTGTCACCATTCTTGTTGCTTTTTAAAAATCAGGCTAATCATGTGGTCCATGTCTCTTCAAAGCTTGACCTGCACAAATGCCATATTTCTATTTGGACCACATATTCTCCATTTTGCATTGAGCAGTAGAGTACAGTGGAAAGGGAATAAGAATACTGATTATTCTGAACAGTTTAGTCCCAAGAGAATAGCGTTTTAAAAAAGAAAAACAAGATTTGGAGTCATTGTGGGTTATTTTTGGTGGGATGGAGGATCTTAAAAATGCCTAATTGTGAGAGAATCAATTGCTGAAAGTGTTAAAATTTCTGAAAATAAATGCTTAATTACATATACAGGAATTAAATAGTTTGGAAGAGGGTTGGATTATCATTACCTTTACAATACTGTATAATCAGAAGTTCTCTGAACCTCAATTGTATATCTAGACATAAAAATTGTTTTCTGTATAGGATGTTGTTTGGTTTGTTTCTGAGTGTTTAAATTTTGCAAAAACAAATGTTAAATTTGTGCTTCAGTACCTAGATAAATTGGAAAGGTTAATGTTCTAGTTTCTGGAAGGTAAGCCTGGGAGACACATAAGCAATTCACTGCTATAATTTAGTTGATGTAAAATGACGGAAACTGACTCAATATGTCAGGTTTAACTCTGCCCAAAAGCAGCAGACATGTAAGCAGATGTGCAATAAAAAATGATCTTGATCCATTTCACTAATGTGTGCTTGACATTTTTTACTATATTGACATTTATTATGGAAAGAGTTAATAATTATTTTTTCTGATGTGCTACACTAGTGGCCAGTATATGGTTAAGTTGATGCTGTATTTATTCTAAGACGGATTTAAAAAGGCAGTTTTCTAAATATGAACTTGTGAATTTTTGTATGTGTGTTTGAGTAAATTGAGAAATGAATTTTATAAATGTTCTATTGATGTTGCAGTAAAGAAGCCTTTTGAAGTAA