| Gene Name | Hras |
|
| Specie | Rattus norvegicus | |
| Full Name | HRas proto-oncogene, GTPase | |
| Also known as | HRAS1|c-H-ras | |
| Coordinate | chr1:214178404-214181841 | |
| Strand | - | |
| Gene summary | Predicted to enable GTPase activity; guanyl ribonucleotide binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular senescence; positive regulation of DNA replication; and positive regulation of ERK1 and ERK2 cascade. Acts upstream of or within positive regulation of Ras protein signal transduction. Located in intracellular membrane-bounded organelle and plasma membrane. Used to study diabetic retinopathy and liver carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Orthologous to human HRAS (HRas proto-oncogene, GTPase). [provided by Alliance of Genome Resources, Apr 2022] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| HrasP1 | chrX:74371289-74372495 | - |
Intergenic |
N/A | UCSC |
| >XM_017589006.1 |
| AGCAGCGGCTTCTGACGGATGGGTTGCTCAGCCAATCATAACAGGTGGCGGTGGGGCGGAGTTCGACCAATCATCGGCGGCCTCGAGTTGACGGACGGGCGCGGGGCGGAGCGGGGCGGGGCGAGCGCGGGCCCGGCCAAGTCCCCGCCGTCCGCGCCCGGCGCCCGCAGCCCGAGCCGCACCCGCCGCGGACGGAGCCCATGCGCGGGCCCAGTCGGCGCCCGTCCGCGCCCCCGCCCTGCCCCGGCCCCGGCCCCGGGGGCAGTCGCGCCAGCAAGCGGTGGGGCAGGAGCTCCTGGTTTGGCAGCCCCTGTAGAAGCGATGACAGAATACAAGCTTGTGGTGGTGGGCGCTGGAGGCGTGGGAAAGAGTGCCCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAGTATGATCCCACTATAGAGGACTCCTACCGGAAACAGGTAGTCATTGATGGGGAGACGTGTTTACTGGACATCTTAGACACAGCAGGTCAAGAAGAGTATAGTGCCATGCGGGACCAGTACATGCGCACAGGGGAGGGCTTCCTCTGTGTATTTGCCATCAACAACACCAAGTCCTTTGAAGACATCCATCAGTACAGGGAGCAGATCAAGCGGGTGAAAGATTCAGATGATGTGCCAATGGTGCTGGTGGGCAACAAGTGTGACCTGGCCGCTCGCACTGTTGAGTCTCGGCAGGCCCAGGACCTTGCTCGCAGCTATGGCATCCCCTACATTGAAACATCAGCCAAGACCCGGCAGGGTGTGGAGGATGCCTTCTACACACTAGTACGTGAGATTCGGCAGCATAAACTGCGGAAACTGAACCCGCCTGATGAGAGTGGCCCTGGCTGCATGAGCTGCAAGTGTGTGCTGTCCTGACACCAGGTGAGGCAGGGACCAGCAAGACATCTGGGGCAGTGACCTCAGCTAGCCAGATGAACTTCATATCCACTTTGATGTCCCTGCTCCCCCAATTCTGCCAATCCCCCTGCCTGCAGTCAGTCATGTCCTTTGTGCCCGTCCCGGCACAGGCTCAGGACGAGGAGGTGCCGGATGCAGGGAGGAGGTGCTGTCggaaggaaggaaagaggagggaaggaaggaaACGATGCTGGAGCCAGTCCAGTCCAGGGATGGTGGACAGATGTGACCAAGACCTTCGCATGGACAATTTGAACAGACTGTCATGAACTATCCCTGTTGCCACTGGCACCCAAGTCCTCCGCCCCTCTCAGCTCCCTTGGGCGCCTATGAGGGCACATGTTGAATCACAGTAAATTATTTGATGGTCTTGACTTG |