Summary

Gene Name	Ddit3
Specie	Rattus norvegicus
Full Name	DNA-damage inducible transcript 3
Also known as	CHOP|CHOP-10|Chop10|Gadd153|RM4
Coordinate	chr7:70578564-70585074
Strand	+
Gene summary	Enables DNA-binding transcription factor activity and protein heterodimerization activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including cellular response to manganese ion; positive regulation of autophagy in response to ER overload; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Part of CHOP-C/EBP complex. Biomarker of several diseases, including borna disease; brain ischemia; chronic obstructive pulmonary disease; pulmonary venoocclusive disease; and ureteral obstruction. Human ortholog(s) of this gene implicated in myxoid liposarcoma. Orthologous to human DDIT3 (DNA damage inducible transcript 3). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Ddit3

Retroname	Coord	Strand	Genomic Region	ENSG
Ddit3P1	chrX:81208669-81209320	+	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>NM_024134.2

GGTCAGTATCTTGAGTCTAATACGTCGATCATACCATGTTGAAGATGAGCGGGTGGCAGCGACAGAGCCAAAATAACAGCCGGAACCTGAGGAGAGAGAAACCGGTCCAATTACAGTCATGGCAGCTGAGTCTCTGCCTTTCGCCTTTGAGACAGTGTCCAGCTGGGAGCTGGAAGCCTGGTATGAGGATCTGCAGGAGGTCCTGTCCTCAGATGAAATTGGGGGCACCTATATCTCATCCCCAGGAAACGAAGAGGAAGAATCAAAAACCTTCACTACTCTTGACCCTGCATCCCTAGCTTGGCTGACTGAGGAGCCAGGGCCAGCAGAGGTCACAAGCACCTCCCAAAGCCCTCGCTCTCCAGATTCCAGTCAGAGTTCTATGGCTCAGGAGGAAGAAGAGGAAGATCAAGGAAGAACTAGGAAACGGAAACAGAGTGGTCAGTGCGCAGCCCGGGCTGGGAAACAGCGCATgaaggagaaggagcaggagaatgagaggaaagTGGCACAGCTTGCTGAAGAGAACGAGCGGCTCAAGCAGGAAATCGAGCGCCTGACCAGGGAGGTAGAGACCACACGGCGGGCTCTGATCGACCGCATGGTCAGTCTGCACCAAGCATGAACTGTTGGCATCACCTCCTGTCTGTCTCTCCCGGAGTGTACCCAGCACCATCACGCCAGTGCCAAGCATGTAATCTCCAGTGCACATGCTGAGGAGGGGACTGAGGGTAGACCAAAGGAGAGGGGCTTGTACACTGTACATTCTTTATTACTGTCCATACCCAGTAAAGTGACTTTGTGTGAACATTC