Summary

Gene Name	Twnk
Specie	Rattus norvegicus
Full Name	twinkle mtDNA helicase
Also known as	Peo1
Coordinate	chr1:264756060-264762892
Strand	+
Gene summary	Predicted to enable several functions, including 5'-3' DNA helicase activity; identical protein binding activity; and protease binding activity. Involved in cellular response to glucose stimulus. Located in mitochondrion. Human ortholog(s) of this gene implicated in Perrault syndrome; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3; chronic progressive external ophthalmoplegia; and mitochondrial DNA depletion syndrome 7. Orthologous to human TWNK (twinkle mtDNA helicase). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Twnk

Retroname	Coord	Strand	Genomic Region	ENSG
Peo1P1	chr1:150374660-150376894	+	Intragenic	N/A	UCSC

Expression

Transcript Sequences

>NM_001107599.1

AGGAGAGTGGTGACGCGAAGctgggggcgggagcgtggagcttctgaagccgagggtagagccctggagcctgTAAGGGAGCCGGGTAGGAGCGCGTGACCTCCAGCTGTGTGGAGGGTCCCTGTGACTGCTAAGAGCTAAGAGCGCCTGGAGTTGGGGTTCAGACAGGATGCAGAGAGCTATAGAGATGAGGTTGGCGAGAAGAGTCCGTAGAGGGGTAGTAGACGTGAAGAGATGATACAGAGAAGCCTTTTAGATTGAGGGGCCGTAGAAGGCTTTAGAAGTGAGCTGGTGGAGAGAAATCGTAAAGGACCTACAAGTATGAGAGTCTTCAGAGAGGGGCGTAGACGCGAAAGGGTAGTATAGGTGTGTGGGGTTGAAGTAACAATATACAGGCAACCAAGGGGATTAAGAATTGTGTTCGTggggctggggatttagctcagtggtagagcgcttacctaggaagcgcaaggccctgggttcggtccccagctccgaaaaaaaaaaagaacaaaaaaaaaaaaaaaaaaacaaaaaaaacccaaaaaacaagaaTTGTGTTCGTAAAGAAATTTGAGGAGAAATAGAGAAAAGGTAGCAATAGTGAGTTCTGTGAGTTCTTGTGAAGGGCTCCTAGGGTCTGGCCTATTAAAGGTACAAAACCAGACACCAAAAGTTTTTGCAGTAGTGGCATCCCACTCCATTAGGAATGTGGCTCCTTCTCCGGCGTGCTTATCCCCTCCGGATCTTGCTGCCACTGCGTGGGGAGTGGATGGGTAGGAGAGGCCTGCCCCGAAGCTTGGCTCCAGGCCCTCCCCGAAGAAGGTACAGAAAAGAAGCGCTTCCAGCCTTAGAGGTACCAGTATCACCTGTGACTACAACTGAAATCCGCCAATATTTACGAGCACATGGGATCCCCTTCCAGGATGGCCACAGCTGCCTTCGAGCACCAAGTCCCTTTGTGGCACCCTCAGACATCAAAAATCAGAAGAAGGATGCTACCACTTCCTTCTGCCTCTTCATCGACAAGACCACAGGACACTTTCTCTGCATGACCAGCCTAGCAGAAGGGAGCTGGGAAGACCTCCAGGCCAGTGTGGAGGGACGAGGCGATGGGGCCAAAGAGGGAATCCTACTTGGGGAGGGCCCAGAAGCTGAGGACAGGGAGGAGGTCTTGAGAATCTGGAACCGAGCCATACCTCTTTGGGAGCTGCCTGATCCCCAGGAAACCCAGCTAGCTCGTGTGATGTTTGGCCTTACCAAGGTGACAGATGACACACTCAGGAGATTCAATGTCCGCTATCTTCGATCTACTCGAAGTCTGGTCTTCCCTTGGTTCACCCCTGGGAGCTCAGGATTACGTGGCCTGAAGCTACTAGGGGTTGAGGGTCAGGAAAATGGAGTACAGTATGTAGAGACCACCATTCCCCGGCCTGGTGTCTATCACAACCTATTTGGATTACCCCTGATCGGCCGTAGAGACACTGAGGTGGTCCTGACAAGTCGAGAGCTGGACAGCCTGGCCTTGAGCCAGTCCACGGGGCTGCCAACCCTTTCCCTACCCCGAGGAACGGTCTGCTTACCCCCAGCCCTACTCCCTTACCTCGAACAGTTCCGGAGGATTGTGTTCTGGCTAGGGGATGACCTTCGATCGTGGGAAGCTGCCAAACTGTTTGCCCGAAAACTGAACCCCAAGCGATGCTCTTTGGTGAGGCCTGGGAACCAACAACCTCGTCCCCTGGAGGCCTTAAACCAAGGCTTAAGTCTTCCCCGTATTCTCCGTACTGCCCTCCCTGCCTGGCACAAGTCTATTGTGTCTTTTCGCCAGCTCCGAGAAGAGGTTTTAGGAGAGCTATCAAATGTGGACCAAGCAGCCGGTGTCCGTTGGAGCCGATTCCCAGACCTTAATCGGCTGCTGAAGGGTCATCGGAAGGGCGAGCTGACGGTCTTTACAGGGCCAACAGGCAGTGGCAAGACAACATTCATCAGTGAGTATGCCCTGGACTTGTGTACCCAGGGAGTGAACACACTGTGGGGTAGCTTTGAGATCAGCAATGTGAGACTAGCCCGGGTCATGCTGACTCAGTTTGCTGTGACACGGCTAGAAGAACAACTGGACAAGTATGAAGAGTGGGCAGACCGTTTTGAGGACCTGCCTCTCTATTTCATGACTTTCCACGGACAACAGAGCATCAGGTCTGTCATAGACACAATGCAACATGCTGTCTACGTCTATGACGTTTGTCATGTAGTCATCGACAACTTGCAGTTCATGATGGGTCATGAGCAGCTCTCTACTGACAGGATCGCAGCTCAAGACTACATTGTTGGAGCCTTTCGGAAGTTTGCCACAGACAATAGCTGCCACGTGACTCTGGTTATTCACCCACGGAAAGAAGATGACGACAAGGAACTACAGACAGCATCCATTTTTGGCTCAGCCAAAGCCAGCCAAGAAGCAGACAATGTTCTGATCTTGCAGGACAGGAAGCTGGTGACTGGGCCTGGGAAACGGTATCTGCAGGTGTCCAAAAATCGCTTTGATGGAGACGTAGGCGTCTTCCCACTTGAGTTCAACAAGAGTTCCCTTACCTTCTCCATCCCACCTAAGAGCAAAGCCCGACTCAAGAAGATTAAGGATGACAATGGACTAGTGGCCAAGAAGTCCTCCTCTGGAAAAAAAGGGTCTGCGCACCAGAACTCTGAGACTTGCATAGGCCAGGACCCCTGCCAGCCAGATACCTCCCCGTCCTCAAGGTGAATGCAGTCAGAGCTGCTTGCTGAAGTGACCCTGGTGAACCAGGCTGACACAGACTCTTGGCCTTCTGCTGGGGCTCGTCCCGAGTGAGCCTTTCCCAGCCCAGGGCTCGGTTCCATGGTGAAAAGTTTAATTCAGCAGCTACTAAGGCTCTCCTATATGCTGGTTCAGGTTTTTTCCCCATAGGTTTTCATGTATAGCACTGAAAAGACAAAGTCTGTTTCCAAAGAACCAGCATCTTggggttggggatttagctcagtggtagagcgcttgcctaggaagcgcaaggccctgggttcaatccccagctccgaaaaaaaagaaccaaaaaaaaaAAAAAAAAAAGAACCAGCATCTTGGTGAAAGGAACAAAGCTAAGTGGGACTGCTCAGCTAGTTTTGATCAGTCACCCTAAAAAGATGGCTGATCAGAGTGCATGTGAGAACCATGGTCTGGTGAACCTCTGGAGAAAGGGATCCAGGTGGAGAAACACCAAAATCACAGGGGGGAATGAGCAAGTCAGATAAAGAGGGCGGACCCTGAACCTGCCACGAAACAGGAGGCTTGCTGGGACTCCAGCATGTTGGCATTCGGAGCGGAAGAGTAATGCAGTGGGCACCTCTCTGCTCTGCTTTGTCGAGCCAGGCATAAGAATTGATCTGAGGTGCTTATCCTGTGCTGTCAGAGCCTCAAAGCTGGACCATGGAGAGAAGCTGTGAGCCTGCAGTGCCTGCCCCCTTGATGCCGATTCCACTGTGTGCTGCTGCCTTGGACAGCGGGAGCTAGGACTCTTGGTGGAGCCTTTTCCAGTTGAATGAAGCATTTCTATGGCCTCTG