Summary

Gene Name	Abcg2
Specie	Rattus norvegicus
Full Name	ATP binding cassette subfamily G member 2
Also known as	BCRP1|Bcrp
Coordinate	chr4:88765441-88890268
Strand	+
Gene summary	Enables several functions, including cytoskeletal protein binding activity; efflux transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including cellular response to lipid; embryonic process involved in female pregnancy; and urate salt excretion. Located in external side of apical plasma membrane and nucleus. Biomarker of diabetes mellitus; secondary hyperparathyroidism; status epilepticus; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Abcg2

Retroname	Coord	Strand	Genomic Region	ENSG
Abcg2P1	chr18:83454754-83455965	+	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>NM_181381.2

AGCGTGTGTAGGTCGGTGTGCGAGTCAGGGCGCGCGGCTGCTGCTCCGCCCGGGACAGCTAGAAAGGCATAGATCCTAAAGATGTCTTCTAGTAATGACCACGTGTTAGTACCGATGTCACAGAGAAACAAGAACGGCCTTCCTGGAATGAGCTCCAGAGGCGCGAGGACGCTCGCAGAGGGAGATGTGCTAAGTTTTCATCACATCACCTATCGAGTGAAAGTGAAGAGTGGCTTTCTAGTCCGGAAAACAGCTGAGAAAGAAATACTATCAGATATCAATGGGATCATGAAACCTGGTCTTAATGCTATTCTGGGACCCACAGGCGGAGGCAAGTCTTCGTTGCTAGATGTCCTAGCAGCAAGGAAAGACCCACGGGGATTATCTGGAGATGTTTTGATAAACGGGGCACCTCAACCTGCCAATTTCAAATGCAGTTCAGGTTATGTGGTTCAAGATGACGTTGTGATGGGCACCCTGACAGTGAGAGAAAACTTACAGTTCTCAGCAGCTCTTCGCCTTCCAAAAGCTATGAAGACGCATGAAAAAAATGAACGGATTAACACGATCATTAAAGAGTTAGGCCTGGACAAAGTAGCAGATTCCAAGGTTGGAACTCAGTTTACCCGTGGTATCTCTGGAGGAGAAAGAAAAAGGACAAGCATAGGAATGGAGCTCATCACTGACCCTTCCATCCTCTTCCTGGATGAGCCCACAACTGGTTTGGACTCAAGCACAGCAAATGCTGTCCTTTTGCTCCTGAAAAGGATGTCTAAACAGGGCCGGACCATCATCTTCTCCATTCACCAGCCTCGGTATTCCATCTTTAAGTTGTTTGACAGCCTCACCTTACTGGCTTCTGGGAAACTCATGTTTCATGGCCCAGCACAGAAGGCCTTGGAGTACTTTGCATCAGCAGGTTACCACTGTGAGCCCTACAACAACCCTGCAGACTTCTTCCTTGACGTCATCAACGGAGATTCTTCGGCTGTAATGTTAAACAGAGGGGAACAAGACCATGAAGCAAACAAGACAGAAGAGCCTTCCAAGAGAGAGAAGCCAATAATAGAAAATTTAGCCGAGTTTTATATCAACTCCACCATCTATGGAGAAACAAAAGCTGAATTAGATCAACTTCCAGTAGCTCAGAAAAAGAAAGGATCATCAGCCTTCAGAGAGCCTGTATATGTTACCTCGTTCTGTCATCAGCTCAGATGGATTGCCAGGCGTTCATTTAAAAACCTGCTCGGGAATCCTCAAGCTTCTGTAGCTCAGTTAATTGTTACAGTCATACTGGGACTGATTATTGGTGCCCTTTACTTTGGTCTGAAAAATGATCCCACTGGAATGCAAAATAGAGCTGGGGTTTTCTTTTTCCTGACTACCAACCAGTGTTTTACCAGTGTGTCAGCTGTGGAGCTCTTCGTAGTGGAGAAGAAACTCTTTATACATGAGTACATCAGTGGATATTACAGAGTATCTTCTTACTTCTTTGGAAAGCTTGTGTCTGACTTACTACCTATGAGGTTCTTGCCAAGTGTTATATACACTTGTATATTATACTTCATGTTAGGACTGAAGAGGACGGTGGAGGCTTTTTTCATCATGATGTTTACCCTTATAATGGTGGCTTATACGGCCAGTTCCATGGCCCTGGCCATAGCCGCAGGCCAAAGCGTAGTGTCTGTAGCAACACTTCTCATGACGATCTCTTTTGTGTTTATGATGCTCTTTTCTGGCCTCTTGGTGAATCTCAGAACCATCGGGCCTTGGCTGTCCTGGCTTCAGTACTTTAGCATTCCTCGATATGGCTTCACAGCTTTGCAGCATAATGAATTCTTGGGACAAGAATTTTGCCCAGGACTCAATGTAACTATGAACAGCACCTGTGTTAACAGCTATACAATATGTACTGGTAATGACTACTTGATAAATCAGGGCATCGATCTGTCACCTTGGGGACTGTGGAGGAATCATGTGGCCCTGGCTTGCATGATCATTATCTTCCTCACAATTGCCTACCTGAAATTGTTGTTTCTTAAGAAGTATTCTTAATTTCCCCTTGAAAGGACTATTGATAGTACTCCTATTAAATATGGGCACTTTGATTAACATAGTCAGTGTTCTTTTCTTCACAGTTATTCTGACATACAAAAATACCTAGTACTGAAAACT