| Gene Name | IL6ST |
|
| Specie | Homo sapiens | |
| Full Name | interleukin 6 cytokine family signal transducer | |
| Also known as | CD130|CDW130|GP130|HIES4|HIES4A|HIES4B|IL-6RB|IMD94|STWS2|sGP130 | |
| Coordinate | chr5:55935095-55994963 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| IL6STP1 | chr17:15782993-15786031 | + |
Intergenic |
ENSG00000227018 | UCSC |
| >NM_001364275.2 |
| GGATCTGACAGTGTTCCGGAGCCGGGGCGAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGGGCCGCCCCGGCGCAGCTGAACCGGGGGCCGCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCCAAGGGGTTCGTGCGCTGTGGAGACGCGGAGGGTCGAGGCGGCGCGGCCTGAGtgaaacccaatggaaaaagcatgacatttagaagtagaagacttagcttcaaatccctactccttcacttactaattttgtgatttggAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTGTGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTTTATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAAATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGCTACTCACCCTGTAATGGATCTTAAAGCATTCCCCAAAGATAACATGCTTTGGGTGGAATGGACTACTCCAAGGGAATCTGTAAAGAAATATATACTTGAGTGGTGTGTGTTATCAGATAAAGCACCCTGTATCACAGACTGGCAACAAGAAGATGGTACCGTGCATCGCACCTATTTAAGAGCACCTTCCAAAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAACGAAGCTGTCTTAGAGTGGGACCAACTTCCTGTTGATGTTCAGAATGGATTTATCAGAAATTATACTATATTTTATAGAACCATCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTCCCACACAGAATATACATTGTCCTCTTTGACTAGTGACACATTGTACATGGTACGAATGGCAGCATACACAGATGAAGGTGGGAAGGATGGTCCAGAATTCACTTTTACTACCCCAAAGTTTGCTCAAGGAGAAATTGAAGCCATAGTCGTGCCTGTTTGCTTAGCATTCCTATTGACAACTCTTCTGGGAGTGCTGTTCTGCTTTAATAAGCGAGACCTAATTAAAAAACACATCTGGCCTAATGTTCCAGATCCTTCAAAGAGTCATATTGCCCAGTGGTCACCTCACACTCCTCCAAGGCACAATTTTAATTCAAAAGATCAAATGTATTCAGATGGCAATTTCACTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACAAAAAGCCTTTTCCAGAAGATCTGAAATCATTGGACCTGTTCAAAAAGGAAAAAATTAATACTGAAGGACACAGCAGTGGTATTGGGGGGTCTTCATGCATGTCATCTTCTAGGCCAAGCATTTCTAGCAGTGATGAAAATGAATCTTCACAAAACACTTCGAGCACTGTCCAGTATTCTACCGTGGTACACAGTGGCTACAGACACCAAGTTCCGTCAGTCCAAGTCTTCTCAAGATCCGAGTCTACCCAGCCCTTGTTAGATTCAGAGGAGCGGCCAGAAGATCTACAATTAGTAGATCATGTAGATGGCGGTGATGGTATTTTGCCCAGGCAACAGTACTTCAAACAGAACTGCAGTCAGCATGAATCCAGTCCAGATATTTCACATTTTGAAAGGTCAAAGCAAGTTTCATCAGTCAATGAGGAAGATTTTGTTAGACTTAAACAGCAGATTTCAGATCATATTTCACAATCCTGTGGATCTGGGCAAATGAAAATGTTTCAGGAAGTTTCTGCAGCAGATGCTTTTGGTCCAGGTACTGAGGGACAAGTAGAAAGATTTGAAACAGTTGGCATGGAGGCTGCGACTGATGAAGGCATGCCTAAAAGTTACTTACCACAGACTGTACGGCAAGGCGGCTACATGCCTCAGTGAAGGACTAGTAGTTCCTGCTACAACTTCAGCAGTACCTATAAAGTAAAGCTAAAATGATTTTATCTGTGAATTCAGATTTTAAAAAGTCTTCACTCTCTGAAGATGATCATTTGCCCTTAAGGACAAAAATGAACTGAAGTTTCACATGAGCTATTTCCATTCCAGAATATCTGGGATTCTACTTTAAGCACTACATAAACTGACTTTATCCTCAGACTAGCTGAATGATTTTGTGCTGTTTCAGGATGTTTGCACTGAAGAAAAACAGAAAGCTTATCTGAAATTTATAAAACTTTTTGTTTTGCTACATAGAAAACAGAAGGTATTTGAATAATAAGCAGTGATATGCTTAGTGAGCACAGCTATACTGATTTTGATTAGAATAGTCATCAGAGTGGCTTAGGGACAGTTAATATAAAAGAGGAGCAAGGTGTAGACCATCATCTACTTCTGCTAAAATAACTTAAAAAGAGGTCCATAGGCCATAACTACATGAGCCCAGCTTTTGTAATCTGACAAAAAAATGAGGAGCAGCTTCGTGTATATCAGTGTACACGGTATTCCTTAGGTCCCTTCCATTGGTAGTGATGCTGCGAGTTATTACTGGAGAAAAGGAATTCTAGAGCTTTAACTTGGCAGATTAAAAGTACTCATTTTTTATTCATCAATAATTAGTAATCTCACTAGTTTTCAAAAATTTGCATATTATTGACAACCTCTTTGAAGATGCATTTCACAAACTCAACAGAGTGCCATGATAAGAGCTAGGGATCCCCCAAACTATCTCAAGCATCTAAAAAATTGCCATTTTTAAAGGCTTAAATTGTAGTAGTAAAGGGGAAAACAGGAAGTAGTAGTAAAGGGGAAAAAAAACCAATAAAGCATCTAAAAAATTGGCATGTTAAAAGGCTTAAATTGCTAATGTGTGtatatatatatatatatatacacacacatatCATTGACTTTTCTTAAGACTTCAGAGTACTGGGTAGATGAACACTTTATACAGTATATATCTTCAGCTTAAATTTGTTTTGAGTATTTTTTTTATTTTTAAATAAGTAGGCAAAGATTTAAATTTTTTTATTTTTAGTAAATGTTTGAGGCACACTAAGACAACTTGGGCAATATTTGCCAAAACAAAACAGAACCCCAAAAAATGTACATCTTGTTCTTAGCAAATATCATTATTGTAGAGACACTTAATAAAGAGATGGTATTTTAATGTCTGCAGTTCTGAGGTAGGGTGGAACTTAGTTCTACATTGTGATTTAGGAATTTTTAAAACCTTTTTTCTTCAAGGGAGAAGTGACCCAGGCCTCGAGTTTAGTGCTAAAGCCGCTAGTGTACTTATGCTGTCCCCTAACCACCACGTGCGATATGGAAGCAGATGCTAAATATAGGGGTTTTCTTAGAAAGTAAGAGGAAATTAGCAAGCGTTATTAGTGATTGACTACTGCTATCAAGTGAATTCAAAGGAAACAGGTTTTTATGCCATATTTAAGTTACAGAAACCAGGCATGCTTAGAATAGTTTCTAGAGGTTATTGGAGAATAGAAAGCTAAGAAAACTTGGTATACATTTACAATGGAAATATAATTACACTTTTTACTCTCAGAATATTGTTCACATTAGACTTCCTGTTTATCTTTTATATTCTTGCATTTATATAATGCCTCATCCTTTCAAAGTTCTTTCACATATTATATGATCTTCTTTATGAAAAAAATAGATGTTTCATTCTGATATATTCAGTTTCCCACTTTAGGCAAAAGTAGATTAATAGAATGACGAATTCAAAGTAGATGAGGAAAATCAGGCACAGAGAAGTAAAGGTAGGGATAGACCCAAATTTACACAACAAGATAATGACATCTCCAGCTTTTAAGTTGATCATCAAAGGCTGGGCTGGATTTGTCTTGCTGTATGTGTCAGGAAATTTATACCTATTACATTTTCCATTTTCTCAAAATTTAAGTCACATGACTAATATTTAGCTGCAACTTTCCTCATAACAAATAGTGTCATGAAGAATGTTGTAGTGTGAAGTTTGTACATTTCAGGGTCAGATATACAATATGAACTCTTAATCTACAGGAATGAGAATGGAGGATCATTGAAGGCCATGATATAAACAAATTTGCATGTTGAAGCCTGTATAAAACATGGTACAGTGAGTGAATATACCCCCATCCCCAAGAACACTTTATACATATTAAATGGATATATGATTACTGTGCAAAAATTCATTCTGGAAATGAACATATATTTGAGCACTAATATGTAATGTACACCTGCCCTAAGGAGAAAATAAATTATAAAACTTTTTACATTCAAAATTACTTTCCCAAGCATGTCTTAGAATAATCTATGTGTTGATGCATGTAAATTGTACTTTAGGTAGGCAAAGAAATCTGGTTATTTATGTAAAAACTAGTCTAATAAAGTTAGTTAGTGGCTTTATCACTTTAAATCTTTAGTGTCCAAAAGTGGTGTTTAAAGTAATAGCACATCAGAAAACCTTGTCTGGACAAAACTAGTTCACTCACTGCTTCTGCACCTGCAGTTGCTCCCTTTAGGGTTATAAAATAATGACCCAAATGTTACATGTGTTGATATTATAACTTGTCAGTTACTGATGTCTGTGGTATCCTACCCTCATCTCTGAAAGGGATAATACTGAATAATTATTAGAAAACTATAAAACTTCACACTTTGTACCATTAAAACCTAAAATTTTAATCTTGTCCTTTTTTACTATGGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATTCACATGTTCTGTGTTCATACCTCTTCTCTACCTAATTGTTCATTTAAATTTCAGCCTTATTCCTTGATAAGGGATTTTACCACATGAAGTCATCCAGTGACCCTAGCTCTTATTGTGAAGTTAGTGGAGTATACTTAGAAATGTTACAACTTTAAAATGTTACAAAACATTCATTAAAGCTCATATTTAAAGTAGAGCATCTAGTTTGAGAAATAGAAATCAATTATTAAAGATGTCTTTTTTCTACCCATTTAACTAGTTAAAACCATGACATGTAAATGTAGAAGTAGAATAATCATAGAATTCCCTAAAATATTTCTGTTTACTAACATATATTGACCAAGTACATCAAGCAGGAGAGATCTTCCTTCATTCTGTTATAGTCCACATCATTCTAATTTTGCTCAGTTGTTATTAAGAGCATATTCCTAAACCATACACTTTTGTTTCAATAAAGTTTTATTTTGTTGAGATGAATAAAATAACaaagttataagctgcataagacaaaagttcaattgttcaaaaAAAATTTACTGGGATAGCTTTCTATTACAGGTATTGTTAGATTATATTGTGCTGATAAGATTACTTTCTAAAAAATTTGTACTTTTCTGTAAATTAAAAGAATATGGAGTCATAAAATGGCAAGTGTTTTAGGATTAGCCTAAAATTGGACATTGTCATTGATTTCAAAGAAGGTATGAACTAGCAGTCTTACAGCCTAATTCTTCTTTGGACTGGTCCTTGGCAGCAGTTCCTTTTCAGACTCGATAAACAGAATTCAGATGATGTAAGTCAAAACAAAACTTTACAAAGCCAAGCGTATTATCTTTTGCATTAACCTATTTTTTTCCATCATACATGCTACTAGTATGTGCATTAGCATGATATTCTCATATACATTGCATTAAAAATTAAAAGGTGGCAGCTCAGGGTGAGCTCTTCTGTTGCTCATTTGTTCCTAAATTTTTAAGGGCTTTTTCTCAGTCAATAGTTTGTACAAACTGGTTAGTTTAACTTCATTACCCATTTCATTAAAGTTGATGGGTCGTGTGATGAGATGCATTTAAGGCCGATAGTGATAGATGTTTTTTTTATTTCTTGAACACAGGCTTTGTCTGAATGATGTTCTTTTATCTCTTGAACACAAGCTTTGAATGATAACTACAGGTTTTAAGTGCTGTTACATTAATACCATAATGTGATGTGTTAGAAACAAAGGGATATTTCAAAGGTAGATATTTGAAAATTCTCTAGTCTCAATATGTATGTGTATTGAATATACTCTAAAAATAAATGTGCAATTTGCTAGTAGGACAATGCAGTGACTGACTAGCATTAGGTATGTTTCTTTTATATCCTAGCTATGTCCCACTTTCTTCTAAGTGCAATCCTTTCATGTTCACTTGCTGTTTTACCCCATCTACTCTAACTTCATTTGGAAGGCTTGTCTAGAGTATAGCATGTATTTTTACCTTTGCAGTGAATTGCATGTGCTAATTGTAACCACAGCTATTTTTATGTTGACATAACTCCAAATGTTATATTAAATGTTCTATTATATATTAGCTCTAATCCCTTAAGTAAATTTTAAGAAATAAATACTTGTTCAAATTTTTTTTCTGTATGTGGTTACTATCATCTGACTATGCATATTTGTAACAGCATTTATCATTAGTGGTGTTAGCTAAATAAGCATCTTAGTGTAAATGAGATGCTTCGTGTGGGTTTTGTGACATTTTAAATGACATAATGGAATGTGATTTAAAAGAAAACCAGTACACTATCTTGGTCTTAATAACATAGAATGGAGATGGCAAATTTATCCACTAGTTTTCCAGATTTACTATTTAATAGCTGAGGTCTGAAATCGTAGCATCCTCCCTCCTAGTGGACATTaaaaaaaaaaaaaaaaaaaaaaaCCTACTTGGTTGTCAAGAGCCCAAGTATGGAGGTGCTGCGCCATCTTGTGGCCTGTCTGTGCCCACCCTGCACTCTGCTGGAGTCTCCATCCTTGTTGCAGTGAGACTTGAAGTTCAAGATTGATACATGGCATCCTCCTGCTACTTCTTGAGGTTACTAAGTAGTATATGAAACTAATCAGTCAGCAAGTCCACCTGGAAGGAAAAGAAAATCTCAACTATTAATGTGCCTTCACATTGTGATTTTGTCTAAAAAAATGTAGTGAGTCAAAAAACCCACAAGCCAGCCAACAGTAACTCCTTCACATATATACCAGAGTTTATAGAAATAACATGTCAGCTTTGGGCTATGTGCTCCTTTGTTTAAAATCTTCTATTTGGTTATGGCTTGTATAGGCTCAAGCCTGATTTCTTTAAGGTGTGGTGGCTCATCTTATCCTAATGTGTATGATAGATACAGTCCATCCTGCTTTGGAAAAGATTATGTAACTCCTTGAGAGCATACTCTTTCTCTAGCCCAAAGGCAGTGAGAGAGTTTTCTTGTTCAGGATTGCTTAACTTTCCATTTAAGCTTTTTCTTTTTAAATTAATACAAACTTCTACACTTTCAAAATACGAAATATATTACAACTGCGTATAGGCTCTTCCATACTTAAGTCCAGTGCTTGGGCAAGTTAATGGAGTGAAAGACTACAAGCAAAGAGGAACTGAGGTAGAAAAAGAAGAATGTGTGAAAGCAGCAGGAAGCTCAGCCAACTCGAAAGCAGGGTGAACAGCTTGAGTCCTGTTGCTGCTGATCGGGGTTGGCTCTTGGACAACTTAGTAAGATCATGGAAAGGCTGCTTGGGTTCTCCATAGAAAAGTTCTGTCTCCATCAAGGGAGGAAAATGTACCTTTCAACTCAAAATTCAATATTTGTTTTTAAATATAGCTATTTTCCCCAACCGCTAAAGATTTTCAACAGATACGAAGCCAGAGCTTAGTTTTAGAAACCTGTGGACATTCAAACCTGATTCTTTATTCCCTGTGACTATGGTTATGTCATTTTACATGTCAAAAAAGTGTATCTAGAATTGTCATTTCTTATTTTTGAGCTTTTTTTAGTGAGAATTATCCCCTCACTTAAATGGCTTTTTATTTAAACATCTGTGCATTCTGTATGAAATTGTAGTCTTTCTGGGATAACATGGTGAGCTATATGGTGGTAATCCACACACACAAAAATAAAAGCCAAAAAAAAACCAAAA 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