| Gene Name | MRE11 |
|
| Specie | Homo sapiens | |
| Full Name | MRE11 homolog, double strand break repair nuclease | |
| Also known as | ATLD|HNGS1|MRE11A|MRE11B | |
| Coordinate | chr11:94415570-94512701 | |
| Strand | - | |
| Gene summary | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| MRE11P1 | chr3:156111306-156114445 | - |
Intergenic |
ENSG00000242537 | UCSC |
| >XM_017017772.1 |
| ACGTTATCCATGAAGTGTCGCGAGAGAAACGGACGCCGTTCTCTCCCGCGGAATTCAGGTTTACGGCCCTGCGGGTTCTCAGAGGCAAGTTCAGACCGTGTTGTTTTCTTTTCACGGATCCTGCCCTTTCTTCCCGAAAAGAAGACAGCCTTGGGTCGCGATTGTGGGGCTTCGAAGAGTCCAGCAGTGGGAATTTCTAGAATTTGGAATCGAGTGCATTTTCTGACATTTGAGTACAGTACCCAGGGGTTCTTGGAGAAGAACCTGGTCCCAGAGGAGCTTGACTGACCATAAAAATGAGTACTGCAGATGCACTTGATGATGAAAACACATTTAAAATATTAGTTGCAACAGATATTCATCTTGGATTTATGGAGAAAGATGCAGTCAGAGGAAATGATACGTTTGTAACACTCGATGAAATTTTAAGACTTGCCCAGGAAAATGAAGTGGATTTTATTTTGTTAGGTGGTGATCTTTTTCATGAAAATAAGCCCTCAAGGAAAACATTACATACCTGCCTCGAGTTATTAAGAAAATATTGTATGGGTGATCGGCCTGTCCAGTTTGAAATTCTCAGTGATCAGTCAGTCAACTTTGGTTTTAGTAAGTTTCCATGGGTGAACTATCAAGATGGCAACCTCAACATTTCAATTCCAGTGTTTAGTATTCATGGCAATCATGACGATCCCACAGGGGCAGATGCACTTTGTGCCTTGGACATTTTAAGTTGTGCTGGATTTGTAAATCACTTTGGACGTTCAATGTCTGTGGAGAAGATAGACATTAGTCCGGTTTTGCTTCAAAAAGGAAGCACAAAGATTGCGCTATATGGTTTAGGATCCATTCCAGATGAAAGGCTCTATCGAATGTTTGTCAATAAAAAAGTAACAATGTTGAGACCAAAGGAAGATGAGAACTCTTGGTTTAACTTATTTGTGATTCATCAGAACAGGAGTAAACATGGAAGTACTAACTTCATTCCAGAACAATTTTTGGATGACTTCATTGATCTTGTTATCTGGGGCCATGAACATGAGTGTAAAATAGCTCCAACCAAAAATGAACAACAGCTGTTTTATATCTCACAACCTGGAAGCTCAGTGGTTACTTCTCTTTCCCCAGGAGAAGCTGTAAAGAAACATGTTGGTTTGCTGCGTATTAAAGGGAGGAAGATGAATATGCATAAAATTCCTCTTCACACAGTGCGGCAGTTTTTCATGGAGGATATTGTTCTAGCTAATCATCCAGACATTTTTAACCCAGATAATCCTAAAGTAACCCAAGCCATACAAAGCTTCTGTTTGGAGAAGATTGAAGAAATGCTTGAAAATGCTGAACGGGAACGTCTGGGTAATTCTCACCAGCCAGAGAAGCCTCTTGTACGACTGCGAGTGGACTATAGTGGAGGTTTTGAACCTTTCAGTGTTCTTCGCTTTAGCCAGAAATTTGTGGATCGGGTAGCTAATCCAAAAGACATTATCCATTTTTTCAGGCATAGAGAACAAAAGGAAAAAACAGGAGAAGAGATCAACTTTGGGAAACTTATCACAAAGCCTTCAGAAGGAACAACTTTAAGGGTAGAAGATCTTGTAAAACAGTACTTTCAAACCGCAGAGAAGAATGTGCAGCTCTCACTGCTAACAGAAAGAGGGATGGGTGAAGCAGTACAAGAATTTGTGGACAAGGAGGAGAAAGATGCCATTGAGGAATTAGTGAAATACCAGTTGGAAAAAACACAGCGATTTCTTAAAGAACGTCATATTGATGCCCTCGAAGACAAAATCGATGAGGAGGTACGTCGTTTCAGAGAAACCAGACAAAAAAATACTAATGAAGAAGATGATGAAGTCCGTGAGGCTATGACCAGGGCCAGAGCACTCAGATCTCAGTCAGAGGAGTCTGCTTCTGCCTTTAGTGCTGATGACCTTATGAGTATAGATTTAGCAGAACAGATGGCTAATGACTCTGATGATAGCATCTCAGCAGCAACCAACAAAGGAAGAGGCCGAGGAAGAGGTCGAAGAGGTGGAAGAGGGCAGAATTCAGCATCGAGAGGAGGGTCTCAAAGAGGAAGAGCAGACACTGGTCTGGAGACTTCTACCCGTAGCAGGAACTCAAAGACTGCTGTGTCAGCATCTAGAAATATGTCTATTATAGATGCCTTTAAATCTACAAGACAGCAGCCTTCCCGAAATGTCACTACTAAGAATTATTCAGAGGTGATTGAGGTAGATGAATCAGATGTGGAAGAAGACATTTTTCCTACCACTTCAAAGACAGATCAAAGGTGGTCCAGCACATCATCCAGCAAAATCATGTCCCAGAGTCAAGTATCGAAAGGGGTTGATTTTGAATCAAGTGAGGATGATGATGATGATCCTTTTATGAACACTAGTTCTTTAAGAAGAAATAGAAGATAATATATTTAATGGCACTGAGAAACATGCAAGATACAGGAAAAATGAAAATGTTACAAGCTAAGAGTTTACAGTTTAAGATTTTAAGTATTGTTTCCTGAGCATAACTCCATAAGTAAGAAATTTCTAGTTCACAGACATACAATAGCATTGATTCACCTTGTTTTTTTAACCTGGTTGTTGTAGTAAGAGCTTTGTTTCAATATCACTCTTGAGTAAAGATTAAAATAAAGCTACCATTTTACATTTCTATTTCATAATGAAAAACTATGTCAGTATTTTAATATGGTTACATTTAGCCAAAGTTGAGGGAAAGAGCTTATAAAATTTAACTTCTTCATAATTTTAGTAATTTCCTAGAGGTTCTGGGTTTTCTGAAAGTAAAACAATTTATGCGAACCTATGTCTAAATTCACTGTTTGTTACTATGTATGTTTTTTTCCAATGCTTCTTATAAGACTAAATGATTAGAAGTACCTAATAGTTTGAACAGATATGTTTTTATTTAAAAGAGTAGAATAACCTTTCAGAATTACTGAGTTTTTTATTCCAGTTGTAGCAAAGATTTCAAAAGATTGTGTTCCCATTAAGTGGTAGTAATTTCCTTTATTATTCTGTATCCTTAATGGTGTtctctctctctctctctctctctctctctccctctcCCCCCCGTTCCCCACTCTTCCTTTCTCCTTTGCTTTTTCTTCTCTTTCATACATATATGCGTGCCTAGTTCTAGGAGGAAACGGGTTAAAAATTGTTTTAAACTACATCTTGAAAATATTGAAGAATTTGTTTTAGGTAGAGTGGTCAGTTGAACCTTACAGTAAAGTATAGAAATATATTTAATGTGGAATGTCAATGCCAGGATTTCTCATTAACAATATTTTATCTCAACTTTGGTTCCTGTGATACATTTCTGAATGGGCAATTCCAGAAATCTTAGTAGCCCATGTTAAGCTTCTATTTTTTACTTGTTTTCGGGGAGAAATAAGAATTAGACATCTTCAGATTTAAGTTAAATAATCCCATTCTTTATAATCCTCTGTAAAAAGATCCCTGAGATTATTCCTTCTTCTAGTTTTATGCGACAGCTTTACTTTAAAATTCAAGTTATACATCTTGGGAGTACAATGGCCCGACATTTCTTCATAGGTAGAAACAAATACTTGACTCAGTGATACTCATGACCATTAGAATAGTCATACCTGGAATGTGTCAAATTATAAGAGACAGACACTTGGTTAGTGGCTGCCTCATATAGCACTTTTGAAGAGGCCTAAGTCAAAACTTGCAATATAACATTCTATTGACTTTCTTAAAAATATTTTTTCTGTACCTAACTTGAGCATAAGGGTTATTTGAGCAAGTAACATTAACTCAGTGGAAGGCATTGTCCTGTGAAATATTCTTAGGCAGATCTGCCCACATCTTTATTGAACTTGAAATCTAATATTTCTAGTATTTGAACAAAGCAGAAGGTTAAGTCAGGGAAGAGCAGTGCTGTCCATGATGTAATGGAAGCTACCAGGGGAGGCAGTGTCTGGATGATGCTGTGCTACCTACCCCTGCACAAGCCATGCTGGCTCAGTCTGAGCTGTGGGCCACATCAGCTAGTGGCTCTTCTCATGCATCAGTTAGGTGGGTCTGGGTGAGAGTTATAGTGAGGGAATGGTCACTAAAGTATCCTGACAAGTTCCTAGGAAAAAAGGAATAAAGTTTTTTTCCTTAAAAAAAAAAAAATTGCTCTTGGCTGTGAAAAGAGGTACTAAATGCGATTCAGTTCACCGCTAAGGAAAGTGATGACATAGCAGTTACAGAGGGTGATAAATCTCTCCAGCTAATTCAGGTCATTTTGTGAATACTATGTATCAAGCCCTGAAAATATGGTAAATAAAACGTGACAGGGAAACCTTTTTTTGATTGAATATTGTTACATAGTTAAATGTGCTATATATCCTTAATATTTTATATTGATCCTGCAAAATCTGTTGGTTTTAGGGGAGTTTTGTTTTTTGTTTCTAACAATTTTCAGACCTGTTGGTATAGGAATGTAGAAGTCTTTCAGATGATTTGAAAGCAGCTGCATTTGCTCTTGGAGGCTTTGGGAGAGCAGGAATGAAAACATTCAGAGGAAGACATCTGTAGGGAATTCTTCTGTTACTTACCAAAGAATAAGTGTCTTTCTGGTGTTTTATTTCCTATCATAAAAATACAACAGTGCATTTACAAGGTTAAAGATTCCTCGAAGTTCTAGGAAATTCTTGAAAATATAAGTGGTGCTTAGAAAATTCAAGCATTTAGGAATGTGACCTTTAATTCAGGTATGTAAAAGACTTTTTTCCCAAACTTTTAAAAGTAGGAAatacaataaatacagaaaagtcatatggttgaataaataattataaattgagcactgatggaatccctctacaggtcaagaaatagcgcagtgtcCTGGATGCCCATTATATTGTTTTCTCCTTTCTGGGTAACAAGCCCTAACTTCTGTAATTTAAAAGCTCCTACTTTTGCCACAAGGTGGTGCTTCTGCCATTAGACGCAGTTAGGAGGATGCAACTGCAAATCTAAAATTACGAAGTTAGTGTAGTTGCAATAAACTTAGAACATATGCATTAATACTAAACCTATGCAGTAATACCATAATTAGCCTTCTAATCATGTAATTTGCTTTACTTAGGTATTTCATTTGGTTCAGCCTGTTATGGAATTTACCAGCTTGATAAATTTGCCTATAAAGTTTTATAAA 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