Summary

Gene Name	ATP1B1
Specie	Homo sapiens
Full Name	ATPase Na+/K+ transporting subunit beta 1
Also known as	ATP1B
Coordinate	chr1:169106690-169132719
Strand	+
Gene summary	The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]

Retrocopy(s) from ATP1B1

Retroname	Coord	Strand	Genomic Region	ENSG
ATP1B1P1	chr4:42029148-42031260	+	Intragenic	ENSG00000249212	UCSC

Expression

Transcript Sequences

>NM_001677.4

ACTCCGAGAGCCGCAGCGGCAGCGGCGCGTCCTGCCTGCAGAGAGCCAGGCCGGAGAAGCCGAGCGGCGCAGAGGACGCCAGGGCGCGCGCCGCAGCCACCCACCCTCCGGACCGCGGCAGCTGCTGACCCGCCATCGCCATGGCCCGCGGGAAAGCCAAGGAGGAGGGCAGCTGGAAGAAATTCATCTGGAACTCAGAGAAGAAGGAGTTTCTGGGCAGGACCGGTGGCAGTTGGTTTAAGATCCTTCTATTCTACGTAATATTTTATGGCTGCCTGGCTGGCATCTTCATCGGAACCATCCAAGTGATGCTGCTCACCATCAGTGAATTTAAGCCCACATATCAGGACCGAGTGGCCCCGCCAGGATTAACACAGATTCCTCAGATCCAGAAGACTGAAATTTCCTTTCGTCCTAATGATCCCAAGAGCTATGAGGCATATGTACTGAACATAGTTAGGTTCCTGGAAAAGTACAAAGATTCAGCCCAGAGGGATGACATGATTTTTGAAGATTGTGGCGATGTGCCCAGTGAACCGAAAGAACGAGGAGACTTTAATCATGAACGAGGAGAGCGAAAGGTCTGCAGATTCAAGCTTGAATGGCTGGGAAATTGCTCTGGATTAAATGATGAAACTTATGGCTACAAAGAGGGCAAACCGTGCATTATTATAAAGCTCAACCGAGTTCTAGGCTTCAAACCTAAGCCTCCCAAGAATGAGTCCTTGGAGACTTACCCAGTGATGAAGTATAACCCAAATGTCCTTCCCGTTCAGTGCACTGGCAAGCGAGATGAAGATAAGGATAAAGTTGGAAATGTGGAGTATTTTGGACTGGGCAACTCCCCTGGTTTTCCTCTGCAGTATTATCCGTACTATGGCAAACTCCTGCAGCCCAAATACCTGCAGCCCCTGCTGGCCGTACAGTTCACCAATCTTACCATGGACACTGAAATTCGCATAGAGTGTAAGGCGTACGGTGAGAACATTGGGTACAGTGAGAAAGACCGTTTTCAGGGACGTTTTGATGTAAAAATTGAAGTTAAGAGCTGATCACAAGCACAAATCTTTCCCACTAGCCATTTAATAAGTTAAAAAAAGATACAAAAACAAAAACCTACTAGTCTTGAACAAACTGTCATACGTATGGGACCTACACTTAATCTATATGCTTTACACTAGCTTTCTGCATTTAATAGGTTAGAATGTAAATTAAAGTGTAGCAATAGCAACAAAATATTTATTCTACTGTAAATGACAAAAGAAAAAGAAAAATTGAGCCTTGGGACGTGCCCATTTTTACTGTAAATTATGATTCCGTAACTGACTTGTAGTAAGCAGTGTTTCTGGCCCCTAAGTATTGCTGCCTTGTGTATTTTATTTAGTGTACAGTACTACAGGTGCATACTCTGGTCATTTTTCAAGCCATGTTTTATTGTATCTGTTTTCTACTTTATGTGAGCAAGGTTTGCTGTCCAAGGTGTAAATATTCAACGGGAATAAAACTGGCATGGTAAttttttttttttttttttttttgttttttGGCTCTTTCAAAGGTAATGGCCCATCGATGAGCATTTTTAACATACTCCATAGTCTTTTCCTGTGGTGTTAGGTCTTTATTTTTATTTTTTTCCTGGGGGCTGGGGTGGGGGTTTGTCATGGGGGAACTGCCCTTTAAATTTTAAGTGACACTACAGAAAAACACAAAAAGGTGATGGGTTGTGTTATGCTTGTATTGAATGCTGTCTTGACATCTCTTGCCTTGTCCTCCGGTATGTTCTAAAGCTGTGTCTGAGATCTGGATCTGCCCATCACTTTGGCTAGTGACAGGGCTAATTAATTTGCTTTATACATtttcttttactttccttttttcctttcTGGAGGCATCACATGCTGGTGCTGTGTCTTTATGAATGTTTTAACCATTTTCATGGTGGAAGAATTTTATATTTATGCAGTTGTACAATTTTATTTTTTTCTGCAAGAAAAAGTGTAATGTATGAAATAAACCAAAGTCACTTGTTTGAAAATAAATCTTTATTTTGAACTTTATAAAAAGCAATGCAGTACCCCATAGACTGGTGTTAAATGTTGTCTACAGTGCAAAATCCATGTTCTAACATATGTAATAATTGCCAGGAGTACAGTGCTCTTGTTGATCTTGTATTCAGTCAGGTTAAAACAACGGACAATAAAAGAATGAACACA