| Gene Name | MRPL2 |
|
| Specie | Homo sapiens | |
| Full Name | mitochondrial ribosomal protein L2 | |
| Also known as | CGI-22|MRP-L14|RPML14 | |
| Coordinate | chr6:43054029-43060180 | |
| Strand | - | |
| Gene summary | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| MRPL2P1 | chr12:89752910-89753867 | + |
Intergenic |
ENSG00000257480 | UCSC |
| >NM_015950.5 |
| AACGTCATCTAGGAGCACCGAGCAGCTTGGCTAAAAGTAAGGGTGTCGTGCTGATGGCCCTGTGCGCACTGACCCGCGCTCTGCGCTCTCTGAACCTGGCGCCCCCGACCGTCGCCGCCCCTGCCCCGAGTCTGTTCCCCGCCGCCCAGATGATGAACAATGGCCTCCTCCAACAGCCCTCTGCCTTGATGTTGCTCCCCTGCCGCCCAGTTCTTACTTCTGTGGCCCTTAATGCCAACTTTGTGTCCTGGAAGAGTCGTACCAAGTACACCATTACACCAGTGAAGATGAGGAAGTCTGGGGGCCGAGACCACACAGGCCGAATCCGGGTGCATGGTATTGGCGGGGGCCACAAGCAACGTTATCGAATGATTGACTTTCTGCGTTTCCGGCCTGAGGAGACCAAGTCAGGACCCTTTGAGGAGAAGGTTATCCAAGTCCGCTATGATCCCTGTAGGTCAGCAGACATAGCTCTGGTTGCTGGGGGCAGCCGGAAACGCTGGATCATCGCCACAGAAAACATGCAGGCTGGAGATACAATCTTGAACTCTAACCACATAGGCCGAATGGCAGTTGCTGCTCGGGAAGGGGATGCGCATCCTCTTGGGGCTCTGCCTGTGGGGACCCTCATCAACAACGTGGAAAGTGAGCCAGGCCGGGGTGCCCAATATATCCGAGCTGCAGGGACGTGTGGTGTGCTACTGCGGAAGGTGAATGGCACAGCCATTATCCAGCTGCCCTCTAAGAGGCAGATGCAGGTGCTGGAAACGTGCGTAGCAACAGTAGGCCGAGTATCCAACGTTGATCATAACAAACGGGTCATTGGCAAGGCAGGTCGCAACCGCTGGCTGGGCAAGAGGCCTAACAGTGGGCGGTGGCACCGCAAGGGGGGCTGGGCTGGCCGAAAGATTCGGCCACTACCCCCCATGAAGAGTTACGTGAAGCTGCCTTCTGCTTCTGCCCAAAGCTGATATCCCTGTACTCTAATAAAATGCCCCCCCCCCCCGTTTTAATCTGTTACTGTGGttttgttttgggtgttttttgttttttttgttgttgttttttttttGCGGGGGAGGGGATGGTACAGACTAAACGTGGGGAAAAGAAGTAAAAAGTGTGGAAGAGAAAGTAcaggacactgggtctgtccccaccccaattcccttacaagtaatggagccggggatggaaataaatgacgtccaaggtc |