Summary

Gene Name	ATP5MC3
Specie	Homo sapiens
Full Name	ATP synthase membrane subunit c locus 3
Also known as	ATP5G3|DYTSPG|P3
Coordinate	chr2:175176258-175181710
Strand	-
Gene summary	This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]

Retrocopy(s) from ATP5MC3

Retroname	Coord	Strand	Genomic Region	ENSG
ATP5MC3P1	chr6:7331151-7331600	-	Intragenic	ENSG00000219375	UCSC

Expression

Transcript Sequences

>NM_001689.5

AGTCCCACTCCTTCGACCTCTGCCGCAGCCCGTGCCGCCGCCGCCTCCTGGGAAGAGAGGAAGCGGGAGAGGAGCCCACGTCGCCTGTCACCCAATATCTCCAGCCGCGCAGTCCCGAAGAGTGTAAGATGTTCGCCTGCGCCAAGCTCGCCTGCACCCCCTCTCTGATCCGAGCTGGATCCAGAGTTGCATACAGACCAATTTCTGCATCAGTGTTATCTCGACCAGAGGCTAGTAGGACTGGAGAGGGCTCTACGGTATTTAATGGGGCCCAGAATGGTGTGTCTCAGCTAATCCAAAGGGAGTTTCAGACCAGTGCAATCAGCAGAGACATTGATACTGCTGCCAAATTTATTGGTGCAGGTGCTGCAACAGTAGGAGTGGCTGGTTCTGGTGCTGGTATTGGAACAGTCTTTGGCAGCCTTATCATTGGTTATGCCAGAAACCCTTCGCTGAAGCAGCAGCTGTTCTCATATGCTATCCTGGGATTTGCCTTGTCTGAAGCTATGGGTCTCTTTTGTTTGATGGTTGCTTTCTTGATTTTGTTTGCCATGTAACAAATTACTGCTTGACATGTTGGCATTCATATTAATTACGGATGTAATTCTGTGTATCTTACTGTGACTCCGAAAACTGTAGTATTGGTGTCATGGGAATGTACGTTATTTCCAAAGTCATTTCATTAAAGATGAAAACTTTAATTTCTTCTGTGATTTGTACTTACACTAAGTTTAGATTATCACAAAGAAGAACGTGCATTCAGGCAGATGCTGTCCCATTCAGAGGAAGCTACAGCAGTTGCTCCACTGATGAAAAATATTCCAATGTAATTTTTATGGGAATTCTTTTATATAGTGTTCTGCATATTGTAATTCATAGGGCTTTTGTTTATTCATATAAAGGATAAATATTTGGGTGTTTTGAGCTTCTATAAAATATGATTAATTAAAGGTAGTTAATACTCAAGATGGTCTTGAGTTTTTAAGGTCTAACATCAGTTAGAATACTTCAAATCAGAATCACCTTCCAAGACTGACTTGACAGGTGGTTCTAAAAATAAATCACGTCAGCTTTTTAGGAAATGAAGCCTTAAGCTAGGGGGTAATGTGACTTTTGTTTTTCAGTAAGTCTCACATTAAGCAATTGTGTGCCTCTAATGAATCTTCCATGTCTTTTCAGAACAGGCTCAGTCCAACTAGCAGCTAGTTTCTTACTTGAACAAGACTATTAAAAACCAAATATCAAAAAACTGAATTGGCTAGATTTTTACAGCCAAAAATTGCTGTAAGGCAGTGTGTATCACTGTTGCTAACATGTTTATAGTGGGAGTCTTGGGGATGATAGCTGGTTCAACAGTATTTTGCTGCTAATACTTTATGTTGCTTCTTGGTCAAACTTTTCCCATTCAAAGGAAGAAGATGGTGCTACTATAGACAGTTTTTCCCCTAGCAAATATATTGTACCATAATATCTATCATCCAAGTTTCAGGGTTTTTTGAAAGTTGATAATTAGGAAAGTGACATTTTACTTTTCTTAGTGCCCTTTGCCTGTTTGATTTCCATTGAGAAAGAGCAGTCACCAAAGTTCCTCAAGTGTCGGAAgaccacctccatcagaatcagtgcttgtttaaaaaataaaaatccctaggttccagacctactgaattggactctttggacatgagactcagcaatctacatctttaaaaaggcttcccaggtggtttttgtgcatactgtttgagagtcactAAGTTATATATATATCCTACCTTCTGTAAAGTGAAATGAGGccccaaaaagctaaagaggtagagctgctacctcgtttttagttgattcatcatctagtctatatcacccaaaagaattggaaataggtattcaaacaaaaacctgtatacaagtattcatagaagcactacttacaatagccgaaaggtagaaacaaccaaatgtctatcagctgatgaatggataagtaaaatacatccatataatggaatattcagccatgaaaaggaatgaggcactgatacataatgaatagatgtgagtgaaccctaagaaagcatgctaagtggaagaagccagccacatgattccatttatatgaaatatccaaaataggcaaatccacggtgacaaagccaattagtagttatcaggaactagggagggggtgaaaagggagtgactgcgtaatgcgtatggggattccttttaggatgatgaaaatTGGATGAATTACAgctggtctgatggtagtgggttatcagaacttattaacattagtgtcattaaagttggtatatagcccctcactgctaaatctGGCTCAAAAATTAAAAGATTATTAAAATTTGatgaattagtggtgatggttgcacaacattgtaaatataataaatgtcactgaattgtacactttaaggtggttaaaatggcaaattttacatgtcttactgaaactactatttAATACAAAGTACATAGTATAAAATTTTAAAAGTGATAGGAAAATGCTTAGATTAATATTCACCTATTCCAAGTATATTTTAAATAAAAACAGTCTTGGTAAAGA