Summary

Gene Name	ATP6V1B2
Specie	Homo sapiens
Full Name	ATPase H+ transporting V1 subunit B2
Also known as	ATP6B1B2|ATP6B2|DOOD|HO57|VATB|VPP3|Vma2|ZLS2
Coordinate	chr8:20197381-20221696
Strand	+
Gene summary	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]

Retrocopy(s) from ATP6V1B2

Retroname	Coord	Strand	Genomic Region	ENSG
ATP6V1B2P1	chr9:121236597-121240013	-	Intragenic	ENSG00000214651	UCSC

Expression

Transcript Sequences

>NM_001693.4

GGGCCAGTCGGGACAGAGGAGACAAGATGGCGCTGCGGGCGATGCGGGGGATTGTCAACGGGGCCGCACCCGAGCTACCCGTGCCCACCGGTGGGCCGGCGGTGGGAGCTCGGGAGCAGGCGCTGGCAGTCAGTCGGAACTACCTCTCCCAGCCTCGCCTCACATACAAGACAGTATCTGGAGTCAATGGTCCACTAGTGATCTTAGATCATGTTAAGTTTCCCAGGTATGCTGAAATTGTCCATTTGACCTTACCGGATGGCACAAAGAGAAGTGGGCAAGTTCTGGAAGTTAGTGGTTCCAAGGCAGTAGTTCAGGTATTTGAAGGGACTTCAGGTATAGATGCTAAGAAAACGTCCTGTGAGTTTACTGGGGATATTCTCCGAACACCGGTGTCTGAGGATATGCTTGGTCGGGTATTCAATGGATCGGGAAAACCCATTGACAGAGGTCCTGTTGTACTGGCCGAAGACTTCCTTGATATCATGGGTCAGCCAATCAACCCTCAATGTCGAATCTACCCAGAGGAAATGATTCAGACTGGCATTTCGGCCATCGATGGGATGAACAGTATTGCTAGGGGGCAGAAAATTCCTATCTTCTCTGCTGCTGGGCTACCACACAATGAGATTGCAGCTCAGATCTGTCGCCAGGCTGGTTTGGTAAAGAAATCCAAAGATGTAGTAGACTACAGTGAGGAAAATTTTGCAATTGTATTTGCTGCTATGGGTGTAAACATGGAAACTGCCCGGTTCTTCAAATCTGACTTTGAAGAAAATGGCTCAATGGACAATGTCTGCCTCTTTTTGAACTTGGCTAATGACCCAACCATTGAGCGAATTATCACTCCTCGCCTGGCTCTAACCACAGCTGAATTTCTGGCGTACCAATGTGAGAAACATGTATTGGTTATTCTAACAGACATGAGTTCTTATGCTGAAGCACTTCGAGAGGTTTCAGCAGCCAGGGAAGAGGTACCTGGTCGACGAGGTTTTCCAGGTTACATGTATACAGATTTAGCCACGATATATGAACGCGCTGGGCGAGTGGAAGGGAGAAACGGCTCGATTACTCAAATCCCTATTCTAACCATGCCTAATGATGATATCACTCACCCCATCCCAGACTTGACTGGCTACATTACAGAGGGGCAGATCTATGTGGACAGACAGCTGCACAACAGACAGATTTATCCACCTATCAATGTGCTGCCCTCACTATCACGGTTAATGAAGTCTGCTATTGGAGAAGGGATGACCAGGAAGGATCATGCCGATGTATCTAACCAGCTATATGCGTGCTATGCTATTGGAAAGGATGTGCAAGCCATGAAAGCTGTCGTTGGAGAAGAAGCCCTTACCTCAGATGATCTTCTCTACTTGGAATTTCTGCAGAAGTTTGAGAGGAACTTCATTGCTCAGGGTCCTTACGAAAATCGCACTGTCTTTGAGACTTTGGACATTGGCTGGCAGCTACTCCGAATCTTCCCCAAAGAAATGCTGAAGAGAATCCCTCAGAGCACCCTCAGCGAATTTTACCCTCGAGACTCTGCAAAGCATTAGCTGCTGCTTCTGCATTGCTCCGCGCTCTTGTGAAATACTGGTTCTGTTTTCTTTATTCCTTTTGCACTCTCGGTTCCCACCTTTGTGTTGGAGTTTACCATGTTACCCTGTAATTAAAAACAAAGAATAGGTAACATATTGTGCCAGTGTTGCAACGTTTTAAACTGCTAACAGACCTTAAAATATCCCCCTACCTGGGTCCTCAGTGCTATGTTTAAAGTGCTGCAGGGATGGAGTGGCGTTTTCTTATTGCTGTATGTATTGTACATAGTGGAGTAGTTAGTTACCTGATAACAGTCTTGTTATTTGGGTCTCTTAGACCTTACCTCTCAACTCCCTCAAGAGTACCAGTCTCTGAAGTTATAATGCTTTGGTCTCTACATTAGGGGCAAGATCCAGTCTGAGAGAAGTCTCCTTTGAGAAGGGCCAAGAGGCTCTTTCCTGAGTGTTTGCTTTCGGTTTGTTGGTATGCCTGTATTGCTGGGCTGTGCTGCTGCTCGAAGCAGATGGTTTTGACTGTCTTTTTGCTCTTTCCTATATAATGAATAGATGAGTGAAAGGAGTTTTCTTTTTCTCTTTAGTACTTACGTATTGGGATTCCTGTGTCTTACAGCTCTCCCTCTCCAAATAATACACAGAATCCTGCAACTTTTTGCACAGCTGGTATCTGTCTGGTAGCAGTGAGACCCCTTGTCTTGGTGATCCTTACTGGGTTTCCAAGCAGAGGAGTCACATGATTACAATTGCCAGTAGAGTTGTTGTTTGGGGTACAAGATGAGAAGAAAGAAAAACCTACAGCCTTTCTACATTCTGACATGCTAACAGTGGTTTAAGTTTCTAAAGTGTTTACCAGATGCTGAAGGCAAGGGGAGGGAGCAGAAGCACTTATGTTTACGGATATTTTAAACTCTGTTAGAGAGCAGCCTTTGAAAATCCCCAATTTGGTTCTGCTTTTTGACCTCTCTCTACCTTTTCAGGGTAATCTTTGTGGCACAAACGATAGCATTTCCAAGCTTTAGAGTTTTCTGAATTCCTGCGCCTTCCTGACGTGAGCCCTGAGCGATCTTCTATGCAGTTCTGCCATGCGTCCTGTTGGTCTCTCTGTGTTCTTTGTTACTTGGGTGCAATAGCAACTTCCCTACCCCGTGCATTCCATCTTTCATGTTGTGTAAAGTTCTTCACTTTTTTCTCTGAGGGCTGGGGGTTGGGGGAGTCAGCATGATTATATTTTAATGTAGAAAATGTGACATCTGGATATAAAATGAAAATAAATGTTAAATTAAATGGACCTTAA