RCPedia: Genes

Summary

Gene Name	Eif2s1	Plot displaying the genomic locations of a parental gene (in chr6) and its retrocopy(ies). Each line represents a retrocopy.
Specie	Rattus norvegicus
Full Name	eukaryotic translation initiation factor 2 subunit alpha
Also known as	-
Coordinate	chr6:102048372-102073041
Strand	+
Gene summary	Predicted to enable ribosome binding activity and translation initiation factor activity. Involved in several processes, including negative regulation of guanyl-nucleotide exchange factor activity; positive regulation of cell death; and response to manganese-induced endoplasmic reticulum stress. Located in cytoplasm; glial limiting end-foot; and nucleus. Part of eukaryotic translation initiation factor 2 complex and translation initiation ternary complex. Used to study middle cerebral artery infarction. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Retroname	Coord	Strand	Genomic Region	ENSG
Eif2s1P1	chr5:64967071-64968435	-	Intragenic	N/A	UCSC
Eif2s1P2	chr16:57880903-57882250	-	Intragenic	N/A	UCSC
Eif2s1P3	chr19:23843663-23844843	+	Intergenic	N/A	UCSC

>NM_019356.1
GTTCGGGATTCACACATACACTTCAGAATGCCGGGTCTAAGTTGTAGATTTTATCAACACAAATTTCCTGAGGTCGAAGATGTAGTGATGGTGAATGTAAGATCCATTGCTGAAATGGGGGCCTATGTCAGCTTGTTGGAATATAATAACATTGAAGGCATGATTCTTCTTAGTGAATTATCCAGACGACGTATCCGTTCTATAAACAAACTGATCCGAATTGGCAGAAATGAATGTGTAGTTGTCATTAGAGTGGATAAAGAAAAAGGATATATAGATTTGTCAAAAAGAAGAGTTTCTCCAGAGGAAGCAATCAAATGTGAAGACAAATTCACAAAATCCAAAACTGTTTATAGCATTCTTCGCCATGTTGCTGAGGTATTAGAGTATACCAAGGATGAGCAGCTGGAAAGCCTATTCCAGAGGACTGCCTGGGTCTTTGATGACAAGTACAAGAGACCTGGATATGGTGCCTATGATGCCTTTAAGCATGCAGTCTCAGACCCATCTATCTTGGATAGTTTAGATTTGAATGAAGATGAAAGAGAAGTACTCATTAACAATATCAATAGGCGTTTGACCCCACAAGCTGTCAAGATTCGAGCAGATATTGAAGTAGCTTGCTATGGTTACGAAGGCATTGATGCTGTAAAAGAAGCCCTGAGAGCAGGTTTGAATTGTTCTACAGAAACCATGCCCATCAAGATTAATCTAATAGCTCCACCCAGGTATGTGATGACAACAACGACCCTAGAGAGGACAGAAGGACTCTCTGTTCTCAATCAGGCTATGGCAGTCATCAAAGAAAAGATTGAGGAGAAGAGGGGAGTGTTCAATGTTCAGATGGAGCCCAAAGTGGTTACAGATACAGATGAGACTGAACTTGCAAGGCAGCTGGAACGGCTtgagagagaaaatgcagaagtggatggagatgatgatgcagaagaaatggaagccaaagctgaagattaaCCTTTTGGAAAACAGTCCAATTTAAGGAGTACGAAGCAGCCCTTTCTGGCTGTAAACCCTAGACTTGAAAGTTTTCCAGTATTGAAAACTTCAAAGCTGAATATTTTTATTTCCAAGTATTTAAGTATTCGACAAGCCAGAATCTAAATGCCCTCCTTCATGTCAGCTGTTTTCACATAGTGGCTCTAACACCTCAAGCGTTTTTAAGGGAGTGGCTTGATTTGACCAGAGACAAATGTTAAACCGCAGTCCTAAAATTGGGCTTGCGGTTTTCATTTCTGATGTCTCTGGATTGGCACCCTTATGGTTTAGAGAATTACCAGGGGCTCCAGACACCAACAATCCCAACCTTTCTATATAAAATGTACTCAAGCAAACATCAAATAAATTTCTGGGATATTT