| Gene Name | OTUD5 |
|
| Specie | Homo sapiens | |
| Full Name | OTU deubiquitinase 5 | |
| Also known as | DUBA|MCAND | |
| Coordinate | chrX:48922024-48960783 | |
| Strand | - | |
| Gene summary | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| OTUD5P1 | chr1:200753474-200753664 | + |
Intragenic |
N/A | UCSC |
| >NM_001136157.2 |
| GCGCCGGGTTTGTTGGGGGGTACTCGGCAGTGCAGCCATGACTATACTCCCCAAAAAGAAgccgccgcctcccgacgccgaccccgccaacgagccgccgccgcccgggccgatgcccccggcgccgcggcgcggcggaggtgtgggcgtgggcggcggcggcacgggcgtgggcggcggcgATCGCGACCGTGACTCCGGCGTCGTGGGGGCCCGTCCGCGAGCTTCGCCACCGCCTCAAGGCCCGCTACCAGGACCGCCGGGCGCTCTTCATCGCTGGGCGCTGGCCGTGCCGCCTGGTGCAGTGGCGGGTCCCCGGCCACAACAGGCTTCTCCACCTCCTTGCGGGGGCCCAGGTGGTCCCGGCGGCGGTCCCGGCGACgcgctgggcgcagcggcggcgggtgtgggtgccgcgggcgtggtggtgggtgtgggtggtgccgtaggcgtgggcgGCTGCTGCTCCGGGCCTGGGCACAGCAAGCGGCGACGTCAAGCTCCCGGGGTTGGCGCGGTTGGCGGGGGCAGTCCCGAGCGTGAGGAGGTCGGCGCAGGCTACAACAGTGAGGACGAGTATGAGGCGGCTGCAGCACGCATCGAGGCTATGGACCCTGCCACTGTCGAGCAGCAGGAGCATTGGTTTGAAAAGGCCCTACGAGACAAGAAGGGCTTCATCATCAAGCAGATGAAGGAGGATGGCGCCTGTCTCTTCCGGGCTGTAGCTGACCAGGTGTATGGAGACCAGGACATGCATGAGGTTGTGCGAAAGCATTGCATGGACTATCTGATGAAGAATGCCGACTACTTCTCCAACTATGTCACAGAGGACTTTACCACCTACATTAACAGGAAGCGGAAAAACAATTGCCATGGCAACCACATTGAGATGCAGGCCATGGCAGAGATGTACAACCGTCCTGTGGAGGTGTACCAGTACAGCACAGAACCCATCAACACATTCCATGGGATACATCAAAACGAGGACGAACCCATTCGTGTTAGCTACCATCGGAATATCCACTATAATTCAGTGGTGAATCCTAACAAGGCCACCATTGGTGTGGGGCTGGGCCTGCCATCATTCAAACCAGGGTTTGCAGAGCAGTCTCTGATGAAGAATGCCATAAAAACATCGGAGGAGTCATGGATTGAACAGCAGATGCTAGAAGACAAGAAACGGGCCACAGACTGGGAGGCCACAAATGAAGCCATCGAGGAGCAGGTGGCTCGGGAATCCTACCTGCAGTGGTTGCGGGATCAGGAGAAACAGGCTCGCCAGGTCCGAGGCCCCAGCCAGCCCCGGAAAGCCAGCGCCACATGCAGTTCGGCCACAGCAGCAGCCTCCAGTGGCCTGGAGGAGTGGACTAGCCGGTCCCCGCGGCAGCGGAGTTCAGCCTCGTCACCTGAGCACCCTGAGCTGCATGCTGAATTGGGCATGAAGCCCCCTTCCCCAGGCACTGTTTTAGCTCTTGCCAAACCTCCTTCGCCCTGTGCGCCAGGTACAAGCAGTCAGTTCTCGGCAGGGGCCGACCGGGCAACTTCCCCCCTTGTGTCCCTCTACCCTGCTTTGGAGTGCCGGGCCCTCATTCAGCAGATGTCCCCCTCTGCCTTTGGTCTGAATGACTGGGATGATGATGAGATCCTAGCTTCGGTGCTGGCAGTGTCCCAACAGGAATACCTAGACAGTATGAAGAAAAACAAAGTGCACAGAGACCCGCCCCCAGACAAGAGTTGATGGAGACCCAGGGATTGGACACCATCTCCCAACCCCAGTACTCCTGCTCTCCGGTGCCACCTCACCTTCTTTGGCTtcttccctcttgcctccttctgttctttctgctctcccctcttttccctcctcctcacttccctctGGCTAGCCCACCCCTGCACTCTCTCTCATTGCCGCTGCCACTATCACCTGTCTCTCTGCCAGCTGATGTGCCCTGTTGCCCCCCACCCCATCCCGCACAGAACCATCCCTGCATTCCACAGGGGACTCGGGCAAGGGTGCCGAagatagacaagaggcacacagagacagaccaactggcagccaggcagccccagaggagagagacattcagacagaGGAAAGTCTCCCTGCCCCTCATTCCTTCCAAGATGAGAAAAACTTGCCGCCACCCCCCGACACTGATGCCAGGGAGGTGGGAGGAAGAAGTGGGAAATTTCCCTTCCCAGTACCCCCAAGAACGTCTGAGCCTTCAATGTTGAATTTTTTCTTTATTAAAATTACTTTTATCTTATAAAATCAACTAATCAAAAATGATATAGACGACAGCACTGGCTCTGTGAAGGTGGCATCTTTCTGGGCAGGCAGGCCATGGGGCATGGAGGAGGGTGCAAAGATATGGGTTGCTGTCTTCTGGCCTCCAGCTGCATGGAGGCCGGCCCAGGGTCTAGGGTGTGCACTGGGCAAGGGCAGGGCGGCAGGTGTCAGGCCGGCTTGGACAATGAAACCCTGACCTTGCTGCATTCCTTTTGCTTCCACCACCACTAGCTTCTTTGGAATCTTGGGGTGGGGGTCATCTTTGGGGATTATGGCTGCCACCCGGGATTTGAGTGTAGGGAGTGTGGGAGCAGCCTTGGCAGATGGGGCACCCGTGCCCTGCAGGTGTTGACAAGATCCGCCATCTGTAATGTCCTTGGCACAATAAAACCAAATGTCAGTTTCCCTGAGCGACTCTGTTCTGTGTGGGGCAGGGGTTGGGCGGGCCTCTGGGCAGAGGATGCAATGGCACGGACCTTGGCTTGACCTCAGAGGTGTGAATGCTCTCCAGCAGGGTCTGTCTGGGGGCCTGGAGTTTGTATTTGATTTGCTGCTTATTAAACCTCCTTCTGGACCTATTGCCACTGGAAAA |