| Gene Name | PSMC6 |
|
| Specie | Homo sapiens | |
| Full Name | proteasome 26S subunit, ATPase 6 | |
| Also known as | RPT5|SUG2|p42 | |
| Coordinate | chr14:52707200-52728590 | |
| Strand | + | |
| Gene summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| PSMC6P3 | chr12:68473730-68475289 | + |
Intergenic |
ENSG00000256075 | UCSC |
| PSMC6P4 | chr17:53681302-53682075 | - |
Intergenic |
ENSG00000262384 | UCSC |
| PSMC6P1 | chr5:33970935-33973006 | + |
Intragenic |
ENSG00000250914 | UCSC |
| PSMC6P2 | chr8:56049680-56051216 | - |
Intergenic |
ENSG00000236814 | UCSC |
| >NM_001366414.2 |
| ATGAGAGACGGCTTCTCATCATGGCGGACCCTAGAGATAAGGCGCTTCAGGACTACCGCAAGAAGTTGCTTGAACACAAGGAGATCGACGGCCGTCTTAAGGAGTTAAGGGAACAATTAAAAGAACTTACCAAGCAGTATGAAAAGTCTGAAAATGATCTGAAGGCCCTACAGAGTGTTGGGCAGATCGTGGGTGAAGTGCTTAAACAGTTAACTGAAGAAAAATTCATTGTTAAAGCTACCAATGGACCAAGATATGTTGTGGGTTGTCGTCGACAGGGCTCTGTGGATGCCGAAAGTTGGCATTTCTAAGATATTTCAGGTTGCATGAGGACAAGACTGTATTTGAAGACTAAAAAACATTAGAAAAGCCGAAGTATATATaagttgagtatcccttatccaaaatgcttgagccagaaatgtgttttagattttggctttttttttttcaggttttagaatatttgtgttgtactggttgagcatccctaattaaaaaaaatcaaaagtttgaaatgctccgatgagcattttctttgagcatcatgtcagcattcaaaaaatttcacattgtggagcattttggattttcagattaagaatactcagcctgTATTTCCTATAGATGTAAACATTGAAATAGCTTCATATTGATTTCTCCTCTTATTTTTTCAAGTAACCTCACTTCTTAGCCGTTTTTTCCTTAATTGTTATATTAATCCTAGTGTTTTGCCTATCTTCCTAAATTTGAAGCTCTTTGTAAAATCCTGTGACAAGTGGTCAGTAATTTATATGATTCCGAAATTGTATTGGCACGCAGTTTTTTAAACTATTAAAAAGTAACTTGggtcgggcggggtggctcatgcctgtaatcccagcactttgggaggctgaggtgggcagatcacgaggtcaggagatcaagaccagcctgaccaacatggtgaaaccccgtctttactaaaaaatacaaaaaaaaattagccgggcatggtggcacacacctgtaatcccagctacttgaggctgaggcaggagaattgcctaaaccagggaggcagaggttgctgtgagccaagatggcgccactgcactccagcctgggcgacagagtgagactccgtactccatctcaaaaaaaaaaGTAACTTTATCTTTGAAAAGTAACAACATCCTGAGAGTGAGGCAGATCTAGTAGATTCTAATTTTAGCCAGATAAGCCAAGAAATTATTTAGTATGATTCAACCTAATGTGTAATGTGTTCAGCATGTGCCTGTCATGTAGCAAAGGCATGAGTGATGGTTGCTGGGTTTTGGGGCTTTAAATTTAAAGCATTTTAATAAAAATCTCTAAGGGGAAACCGTGCATTTTTCTCTACTCTCATGAGCATTTAACACATTCTTCCCAGAAGCTGTACATTTCAAAATAAATCTGATGAGCACACCTTTAAAATGCTTCCCTTTCCTTTCCCTAAAATGTTCACTAAGGGATTTTTCTATAAATGCTTTGGTAGCAATTCCCAAAGTCACTGTACCATTGCTGCCTCAAGCTTTGTGTGTTAGTCATTTCACATTTTACACTGAGATTACACAAAGGGGCATGCTTTTAAGGAGCAGGTGGAAATCACTTTGAATTACTTATTTTATAAGCCATTTTGTTAGCATAGAGTTTATAATCTGATATTTGTGTTCTCTCTGGAGGGTAAAAATGAGTGTTTGGCTTCTAAATATTAAACTCTCGTTAGAGTGTTATTCCGTTTTTAAGTGTTGATGTAATATCTTTTGTTTTACAAAACTAGCTTGACAAAAGTAAGCTGAAGCCAGGAACAAGAGTTGCTTTGGATATGACTACACTAACTATCATGAGATATTTGCCGAGAGAGGTGGATCCACTGGTTTATAACATGTCTCATGAGGACCCTGGGAATGTTTCTTATTCTGAGATTGGAGGGCTATCAGAACAGATCCGGGAATTAAGAGAGGTGATAGAATTACCTCTTACAAACCCAGAGTTATTTCAGCGTGTAGGAATAATACCTCCAAAAGGCTGTTTGTTATATGGACCACCAGGTACGGGAAAAACACTCTTGGCACGAGCCGTTGCTAGCCAGCTGGACTGCAATTTCTTAAAGGTTGTATCTAGTTCTATTGTAGACAAGTACATTGGTGAAAGTGCTCGTTTGATCAGAGAAATGTTTAATTATGCTAGAGATCATCAACCATGCATCATTTTTATGGATGAAATAGATGCTATTGGTGGTCGTCGGTTTTCTGAGGGTACTTCAGCTGACAGAGAGATTCAGAGAACGTTAATGGAGTTACTGAATCAAATGGATGGATTTGATACTCTGCATAGAGTTAAAATGATCATGGCTACAAACAGACCAGATACACTGGATCCTGCTTTGCTGCGTCCAGGAAGATTAGATAGAAAAATACATATTGATTTGCCAAATGAACAAGCAAGATTAGACATACTGAAAATCCATGCAGGTCCCATTACAAAGCATGGTGAAATAGATTATGAAGCAATTGTGAAGCTTTCGGATGGCTTTAATGGAGCAGATCTGAGAAATGTTTGTACTGAAGCAGGTATGTTCGCAATTCGTGCTGATCATGATTTTGTAGTACAGGAAGACTTCATGAAAGCAGTCAGAAAAGTGGCTGATTCTAAGAAGCTGGAGTCTAAATTGGACTACAAACCTGTGTAATTTACTGTAAGATTTTTGATGGCTGCATGACAGATGTTGGCTTATTGTAAAAATAAAGTTAAAGAAAATAATGTATGTATTGGTAATGATGTCATTAAAAGTATATGAATAAAAATATGAGTAACATCATAAAAATTAGTAATTCAACTTTTAAGATACAGAAGAAATTTGTATGTTTGTTAAAGTTGCATTTATTGCAGCAAGTTACAAAGGGAAAGTGTTGAAGCTTTTCATATTTGCTGCGTGAGCATTTTGTAAAATATTGAAAGTGGTTTGAGATAGTGGTATAAGAAAGCATTTCTTATGACTTATTTTGTATCATTTGTTTTCCTCATCTAAAAAGTTGAATAAAATCTGTTTGATTCAGTTCTCCTACATATATATTCTTGTCTTTTCTGAGTATATTTACTGTGGTCCTTTAGGTTCTTTAGCAAGTAAACTATTTGATAACCCAGATGGATTGTGGATTTTTGAATATTATTTTAAAATAGTACACATACTTAATGTTCATAAGATCATCTTCTTAAATAAAACATGGATGTGTGGGTATGTCTGTACTCCTCCTTTCAGAAAGTGTTTACATATTCTTCATCTACTGTGATTAAGCTCATTGTTGGTTAATTGAAAATATACATGCACATCCATAACTTTTTAAAGAGTATGATTCAACGTAATATTTGCTAATATGTGACTGGGTTTTCTTGGTTTATGTAAGACGATAggtccctgttgaggatgtggaggtctggaccctcttccaggaaaaattctaacatacaattttgcgtatactataatttcaggaaatttattgtttcccaagctcatccaaggactcTTTAGGTATGTATGGATACCTGGCTAAGAGTGTATGATGTAGGGGATGTAGGAGTGTCAGAAATGTTCAAAACATGATTTCTGTTACCTATACATGATTCTTATATCATCTGGCAATAAAAGCTATAACAAAGTA |
| >NM_002806.5 |
| ATGAGAGACGGCTTCTCATCATGGCGGACCCTAGAGATAAGGCGCTTCAGGACTACCGCAAGAAGTTGCTTGAACACAAGGAGATCGACGGCCGTCTTAAGGAGTTAAGGGAACAATTAAAAGAACTTACCAAGCAGTATGAAAAGTCTGAAAATGATCTGAAGGCCCTACAGAGTGTTGGGCAGATCGTGGGTGAAGTGCTTAAACAGTTAACTGAAGAAAAATTCATTGTTAAAGCTACCAATGGACCAAGATATGTTGTGGGTTGTCGTCGACAGCTTGACAAAAGTAAGCTGAAGCCAGGAACAAGAGTTGCTTTGGATATGACTACACTAACTATCATGAGATATTTGCCGAGAGAGGTGGATCCACTGGTTTATAACATGTCTCATGAGGACCCTGGGAATGTTTCTTATTCTGAGATTGGAGGGCTATCAGAACAGATCCGGGAATTAAGAGAGGTGATAGAATTACCTCTTACAAACCCAGAGTTATTTCAGCGTGTAGGAATAATACCTCCAAAAGGCTGTTTGTTATATGGACCACCAGGTACGGGAAAAACACTCTTGGCACGAGCCGTTGCTAGCCAGCTGGACTGCAATTTCTTAAAGGTTGTATCTAGTTCTATTGTAGACAAGTACATTGGTGAAAGTGCTCGTTTGATCAGAGAAATGTTTAATTATGCTAGAGATCATCAACCATGCATCATTTTTATGGATGAAATAGATGCTATTGGTGGTCGTCGGTTTTCTGAGGGTACTTCAGCTGACAGAGAGATTCAGAGAACGTTAATGGAGTTACTGAATCAAATGGATGGATTTGATACTCTGCATAGAGTTAAAATGATCATGGCTACAAACAGACCAGATACACTGGATCCTGCTTTGCTGCGTCCAGGAAGATTAGATAGAAAAATACATATTGATTTGCCAAATGAACAAGCAAGATTAGACATACTGAAAATCCATGCAGGTCCCATTACAAAGCATGGTGAAATAGATTATGAAGCAATTGTGAAGCTTTCGGATGGCTTTAATGGAGCAGATCTGAGAAATGTTTGTACTGAAGCAGGTATGTTCGCAATTCGTGCTGATCATGATTTTGTAGTACAGGAAGACTTCATGAAAGCAGTCAGAAAAGTGGCTGATTCTAAGAAGCTGGAGTCTAAATTGGACTACAAACCTGTGTAATTTACTGTAAGATTTTTGATGGCTGCATGACAGATGTTGGCTTATTGTAAAAATAAAGTTAAAGAAAATAATGTATGTATTGGTAATGATGTCATTAAAAGTATATGAATAAAAATATGAGTAACATCATAAAAATTAGTAATTCAACTTTTAAGATACAGAAGAAATTTGTATGTTTGTTAAAGTTGCATTTATTGCAGCAAGTTACAAAGGGAAAGTGTTGAAGCTTTTCATATTTGCTGCGTGAGCATTTTGTAAAATATTGAAAGTGGTTTGAGATAGTGGTATAAGAAAGCATTTCTTATGACTTATTTTGTATCATTTGTTTTCCTCATCTAAAAAGTTGAATAAAATCTGTTTGATTCAGTTCTCCTACATATATATTCTTGTCTTTTCTGAGTATATTTACTGTGGTCCTTTAGGTTCTTTAGCAAGTAAACTATTTGATAACCCAGATGGATTGTGGATTTTTGAATATTATTTTAAAATAGTACACATACTTAATGTTCATAAGATCATCTTCTTAAATAAAACATGGATGTGTGGGTATGTCTGTACTCCTCCTTTCAGAAAGTGTTTACATATTCTTCATCTACTGTGATTAAGCTCATTGTTGGTTAATTGAAAATATACATGCACATCCATAACTTTTTAAAGAGTATGATTCAACGTAATATTTGCTAATATGTGACTGGGTTTTCTTGGTTTATGTAAGACGATAggtccctgttgaggatgtggaggtctggaccctcttccaggaaaaattctaacatacaattttgcgtatactataatttcaggaaatttattgtttcccaagctcatccaaggactcTTTAGGTATGTATGGATACCTGGCTAAGAGTGTATGATGTAGGGGATGTAGGAGTGTCAGAAATGTTCAAAACATGATTTCTGTTACCTATACATGATTCTTATATCATCTGGCAATAAAAGCTATAACAAAGTA |