| Gene Name | PSMD7 |
|
| Specie | Homo sapiens | |
| Full Name | proteasome 26S subunit, non-ATPase 7 | |
| Also known as | MOV34|P40|Rpn8|S12 | |
| Coordinate | chr16:74296814-74306288 | |
| Strand | + | |
| Gene summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| PSMD7P3 | chr1:155845389-155846225 | + |
Intragenic |
ENSG00000234937 | UCSC |
| PSMD7P4 | chr1:185280792-185281888 | + |
Intragenic |
ENSG00000238061 | UCSC |
| PSMD7P2 | chr1:51372227-51373736 | + |
Intragenic |
ENSG00000232027 | UCSC |
| PSMD7P1 | chr17:66197634-66198707 | + |
Intergenic |
ENSG00000266707 | UCSC |
| >NM_002811.5 |
| GGAAGAAGAGGAACTGGGCCTGAAAGGGTACCGGTGACCGCTACTGCTGCCGGTGTTTGCGTGTGGCAGGGAGCCAGGCCTGGCGAGCGGGGTGTGTCGCGATGCCGGAGCTGGCAGTGCAGAAGGTGGTGGTCCACCCCCTGGTGCTGCTCAGTGTGGTGGATCATTTCAACCGAATCGGCAAGGTTGGAAACCAGAAGCGTGTTGTTGGTGTGCTTTTGGGGTCATGGCAAAAGAAAGTACTTGATGTATCGAACAGTTTTGCAGTTCCTTTTGATGAAGATGACAAAGACGATTCTGTATGGTTTTTAGACCATGATTATTTGGAAAACATGTATGGAATGTTTAAGAAAGTCAATGCCAGGGAAAGAATAGTTGGCTGGTACCACACAGGCCCTAAACTACACAAGAATGACATTGCCATCAACGAACTCATGAAAAGATACTGTCCTAATTCCGTATTGGTCATCATTGATGTGAAGCCGAAGGACCTAGGGCTGCCTACAGAAGCGTACATTTCAGTGGAAGAAGTCCATGATGATGGAACTCCAACCTCGAAAACATTTGAACACGTGACCAGTGAAATTGGAGCAGAGGAAGCTGAGGAAGTTGGAGTTGAACACTTGTTACGAGATATCAAAGACACGACGGTGGGCACTCTGTCCCAGCGGATCACAAACCAGGTCCATGGTTTGAAGGGACTGAACTCCAAGCTTCTGGATATCAGGAGCTACCTGGAAAAAGTCGCCACAGGCAAGCTGCCCATCAACCACCAGATCATCTACCAGCTGCAGGACGTCTTCAACCTGCTGCCAGATGTCAGCCTGCAGGAGTTCGTCAAGGCCTTTTACCTGAAGACCAATGACCAGATGGTGGTAGTGTACTTGGCCTCGCTGATCCGTTCCGTGGTCGCCCTGCACAACCTCATCAACAACAAGATTGCCAACCGGGATGCAGAGAAGAAAGAAGGGCAGGAGAAAGAAGAGAGCAAAAAGGATAGGAAAGAGgacaaggagaaagataaagataaggaaaagagtgatgtaaagaaagaggagaaaaaggagaaaaagtaaaACATGTATTAAATAGCTTTTTTAATTTGTAAATTAAAATCTTACAAACTAAATCAGTGTGCTGCTAGAGGGTTCTTTTTCACTTGACATGCTTATTAGAAAGCTGACCCAACAAGAGCTCTCTGCCTCCGGTCACTCTTGCTGTGGTGCTACGTGGAAGTGAATGGAGACTGATCTCAAATCTGAACTGCAGCTTTCGCTGCTGTGAGTTGGGGATATGATAGTCAGCTCAGGCTTCAGATTGTATGAGAAAAATGAAGAGAAGTCAACAAATATTTTGGTACTCTTCATTCATTTATCTCTAAAACCAGGAGTTGAATTTTCCTCATCTTGAAAGACTCTTGGGGTCTGTTTCTGGTATTTTACAAAATTGCTAAGTGGAATGCATGAATTGCATTATGTTCTCTGGTAACACGTAGAGTTCAGACCCTTCTGAACTCTGTTGATAATACCACACCATGTTCTGGACCCATAGCTCTGGCATCCTCAGGGGTTGTGATCCAGCTCCATATATTGTTTACCTTCAAAGATACAATTAAATGGCTTGATTTTTAA |