| Gene Name | PSMD12 |
|
| Specie | Homo sapiens | |
| Full Name | proteasome 26S subunit, non-ATPase 12 | |
| Also known as | Rpn5|STISS|p55 | |
| Coordinate | chr17:67337916-67366587 | |
| Strand | - | |
| Gene summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| PSMD12P1 | chr3:72876689-72878160 | - |
Intragenic |
ENSG00000240135 | UCSC |
| >NM_002816.5 |
| GTGGGTGACGAGTGGTGGCCGAAGCAGGGGGACAGCAAGGGACGCTCAGGCGGGGACCATGGCGGACGGCGGCTCGGAGCGGGCTGACGGGCGCATCGTCAAGATGGAGGTGGACTACAGCGCCACGGTGGATCAGCGCCTACCCGAGTGTGCGAAGCTAGCCAAGGAAGGAAGACTTCAAGAAGTCATTGAAACCCTTCTCTCTCTGGAAAAGCAGACTCGTACTGCTTCCGATATGGTATCGACATCCCGTATCTTAGTTGCAGTAGTGAAGATGTGCTATGAGGCTAAAGAATGGGATTTACTTAATGAAAATATTATGCTTTTGTCCAAAAGGCGGAGTCAGTTAAAACAAGCTGTTGCCAAAATGGTTCAACAGTGCTGTACTTATGTTGAGGAAATCACAGACCTTCCTATCAAACTTCGATTAATTGATACTCTACGAATGGTTACCGAAGGCAAGATTTATGTTGAAATTGAGCGTGCGCGACTGACTAAAACATTAGCAACTATAAAAGAACAAAATGGTGATGTGAAAGAGGCAGCCTCCATTTTACAGGAGTTACAGGTGGAAACCTACGGGTCAATGGAAAAGAAAGAGCGAGTGGAATTTATTTTGGAGCAAATGAGGCTCTGCCTAGCTGTGAAGGATTACATTCGAACACAAATCATCAGCAAGAAAATTAACACCAAATTTTTCCAGGAAGAAAATACAGAGAAATTAAAGTTGAAGTACTATAATTTAATGATTCAGCTGGATCAACATGAGGGATCCTATTTGTCTATTTGTAAGCACTACAGAGCAATATATGATACTCCCTGTATACAGGCAGAAAGTGAAAAATGGCAGCAGGCTCTGAAGAGTGTTGTACTCTATGTTATCCTGGCTCCTTTTGACAATGAACAGTCAGATTTGGTTCACCGAATAAGTGGTGACAAGAAGTTAGAAGAAATTCCCAAATACAAGGATCTTTTAAAGCTTTTTACCACAATGGAGTTGATGCGTTGGTCCACACTTGTTGAGGACTATGGAATGGAATTAAGAAAAGGTTCCCTTGAGAGTCCTGCAACGGATGTTTTTGGTTCTACAGAGGAAGGTGAAAAAAGGTGGAAAGACTTGAAGAACAGAGTTGTTGAACATAATATTAGAATAATGGCCAAGTATTATACTCGGATAACAATGAAAAGGATGGCACAGCTTCTGGATCTATCTGTTGATGAGTCCGAAGCCTTTCTCTCAAATCTAGTAGTTAACAAGACCATCTTTGCTAAAGTAGACAGATTAGCAGGAATTATCAACTTCCAGAGACCCAAGGATCCAAATAATTTATTAAATGACTGGTCTCAGAAACTGAACTCATTAATGTCTCTGGTTAACAAAACTACGCATCTCATAGCCAAAGAGGAGATGATACATAATCTACAATAAGGGTCTTAGTGCTTTAGAAAAAAGTTAAAATTGGAAGTCATTAAAAAAAGACTGTTATAATGGTGTATATGTTGGGGTTTTTTTTCTAAGCTTCTTTGTCTTAAATTTTAAAATAGTGAATATGTTTGAGACTCCCTTTGACCTTTCAGTTCCCCAAGTTCATTGTTAACTTTGCATTTGCAATTGGTGCAAAAATACAGATTTCTGTCGTCTGAATACACAAAAAGTTGTGTCATAACTTACCCAGATATGTTTTTCTATCATTTGAAACCTTTTTAGCTACTGTTTGTTTTCATTCAACTAACAAACATATTCCAATAATAAAAGCAGTATATACATATTTCCTTTCTACAGTTACCTCTGATTCTCAACATTTTGTGGGGTAGTGATTTGGCAAGTGTTTTTTAAATAAAACAAATCTCATTGTAAAGCTATCAGTCATTTAGTAGAATAGAAAAGCAACATAGAGCATACAAGAACATTTGGGATAGAGTTGTGATTTGTGAAGAATTTGTACTTTGATATTGTGGCGGAAAGTCTAGACTGAGTGTGTATGCTGGTAAACTGTAGACttttttttttttttttttGAGTCCGGCTGGTTCCAATCACAGTAGCTTGATTGCTTTCAGCCCTCATCCTCTCACTTGATCAGTTGTTCAACAGAATCAGCTGACATAATTGACACAGTTTATTGGGTGTTAAGTCCGCTCTATAGGGATAGTGACTACtttttttttttttttttttttGCTCTTCTTCCTCTCCCCTTTCTTTATATGGGTTTAAATTTAACATAAAGTTGTTTTTATAAGGCTTATTTGTGGCTTTAACTTGTAAGTCTGATTACATCATTATTGTTCCAAATTCATTATCTCTGTAGGAACTTTTAGTTCCATTATATGAACACTGGATAACCTAATTTTTTTTAATGCTTTAAAAAAATGGCAAAAAGACGTCAGGCCACCCTCATAGTAAGTGGTGTAGTATTAAAATATTTTCACGGAATTAAAAGTAGCTTGCTGTCAAAGAAACACCTGAGATGAATTGGTGTGAACGAATTTTGCAAGTTTAATTTGATTTATTTCAGAGAAAATAGAAAAAACAATGTTAGAAGGTTATTTAAAATGATACTTAAATAAAGAAAGTGTGAGGTCTACTTTAAAAAAATTCAAATGAAGAGAAAAAGAAAAACAGCATTCTAGAAATGGCATTTCTCCTAATTAATTTTCCACTTAATGGAAGATTATCAATTGTCCTATTTTATGATCCCAGGACTGAAGACAGTTGTGGGATATCTGTCATATTTATCCTGTGAGTCATTGTGAATAATGACATACAGTACTGAAGTAATCTGATTTTATTCTTTGGAAATTCAATGCATTGGTCACACTAATAACATCAACATCTGCTATCACTTATCTTTTTAAAACTAACCAAAAAAggccgggtgcagtggatcccagcactttgggaggccaaggcgggtggatcatctaaggtcaggatttcgagactagcctggccaacatggcaaaaccctgtctctactaaaaaaaatacaaaaatttgccgggcgtggtggcgtgtgcctgtagtcccagttacttgggaggctgaggtgggagaattccttgaagccaggaggcggaggttgcagtgagccaagatcacaccattgcactccagcctgggtgacagagtgagactccgtctcaaaaaaaaaaaaacaaaaCTGGAAAGTTCAGAAACAGAAGTTCACACTAACAGAGTATGGTTTTAATTTTCCTTTGAATGAAAAGGATAGAAGATAAAATTGTGTATTGTTAACATGTAAATAAAATTGGAGCTAATTTGAAACTAGCTTCTCAATAACTTCATCTTTCTAGAGACTCATTACCTGTGGGCTTGTCAAACCTGGACTATTTGGCCAAATAGGTTGCTATAGAGATTGCAAGTGTTCCTCCTCtttatttttttcatattttttgagacggagtttcactcttgttgcccaggctggattgcagtgtcacgatctcggctcactgcaacctttgcctcccatattcaagcagttctcctgcctcaacctcccaagtagctgggattataggcgcctgccaccacacctagctaatttttgtgtttttagtagagatggtttcatcatgttggccgggctggtctcaaactcctgacctcaggtgatccacccgccttggctgcccaaagtgctgggattacaggcatgagccactgcacccAACTCCTCTTTCGTCTTTCTTTAACACACACTAGGCTCTTTGTGTATTATGATTCAGTGCTATTTGTAACTGTGTCCCAGTGACCAAATTGCACTCGACTCGATCAGCTGTTCATCCATTTCGTGTTTTTTCCTGTCAAACATTAATCCAGCAAATATATGAGGTATTTACCAATTTATTTTCTTAGTATTACAAAATAATTCATTAGCATAAAGTACAATAGTGAAATATTTGAGTTGTTCGGAACCTCAATTAATCCTGTTTTACATTTCAGACCTAAAGCTGGCAATCAGGAGAAGAAGCACTTTGTTTTAAATGTGGAGAAGATAACACTTGATTCCATTTCATTGTCATTAGTGTATTAACCAGCAGGAGAGGTGATGAGCCATTTTTCAAATGAAATACCTTTTATTTCCATATAATTTTTTTATTTTAGAGTTCAATAGCTGTTTCTATGATTATCCTCAATTTCCATATGTTACTGAATCTGAAAAACATCTTTAAAATTCAAACAGTTCCATTTTCTCTCTTGTAAGTGTTAAATGTGATAAAAGTACATATTTTAAATTGTTTTCAGCTCTTGGATATAGCAGCAATAAAAACACTAATTTGTGGGTATTTAAGAAAACCTGGAGAATAAACTCATACTTTAAAAGATCA |