| Gene Name | MRPL40 |
|
| Specie | Homo sapiens | |
| Full Name | mitochondrial ribosomal protein L40 | |
| Also known as | L40mt|MRP-L22|MRP-L40|MRPL22|NLVCF|URIM | |
| Coordinate | chr22:19432545-19436075 | |
| Strand | + | |
| Gene summary | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| MRPL40P1 | chr12:67351517-67352155 | + |
Intergenic |
ENSG00000256037 | UCSC |
| >NM_001318151.2 |
| GAGGGTAGCCATGACGGCCTCCGTGCTGCGAAGTATCTCGCTAGCCCTGCGCCCGACTAGCGGGTGAGTGCGGACGCTGGCCGGATAGCGGAGTGCCCAGGGCGCGTGCGGGGTCTTCGCGACTGTCCGCCAGGACTCGCCTGTGCTCCCTGCTCGCCTCCCAGTCCACGAATATCTCAGGGATGAGCCATCTGGTCGTGACTCTTATGCATGAAAATCTGAGCACCCTGGCGAGCAGCGGTCCTGCTTAAGTCCTCTGTGGTCTGAACGAAAGATTTTGAAAAACCTTCCACGTTGACCTTGCTGTCATATCAAGCTTCTGGGAACTTGGCAGACGCAGCTTAGAGAGACTCACCAGCGAGCGTCATTGTTGTCTTTCTGGGAACTCATTCCCATGAGATCAGAACCTCTTCGAAAAAAGAAGAAGGTAGATCCTAAAAAAGACCAAGAAGCAAAGGAGCGCTTGAAAAGGAAGATCCGAAAACTGGAAAAGGCTACTCAAGAGCTAATTCCTATTGAAGATTTTATTACCCCTCTAAAGTTCTTGGATAAAGCAAGAGAGCGGCCTCAGGTGGAGCTCACCTTTGAGGAGACTGAGAGGAGAGCTCTGCTTCTGAAGAAGTGGTCCTTGTACAAGCAGCAAGAGCGTAAGATGGAGAGGGACACCATCAGGGCTATGCTAGAAGCCCAGCAGGAAGCTCTGGAGGAACTGCAACTGGAATCCCCGAAGCTCCATGCTGAGGCCATCAAGCGGGATCCTAACCTGTTCCCCTTTGAGAAGGAAGGGCCACATTACACACCACCGATCCCTAACTACCAACCCCCTGAAGGCAGGTACAATGACATCACCAAGGTGTACACACAAGTGGAGTTTAAGAGATAGACTTGCAGGCTGCTATCCTTAACATGCTGCCCCTGAGAGTAGGAATGACCAGGGTTCAAGTCTGCTTTCCACAGAATCAGGCATGCTGTTAATAAATACTGGTTTAATCAAAA |