Summary

Gene Name	Atp5f1a
Specie	Rattus norvegicus
Full Name	ATP synthase F1 subunit alpha
Also known as	Atp5a1
Coordinate	chr18:74156553-74164490
Strand	+
Gene summary	Enables ADP binding activity; ATP binding activity; and protease binding activity. Contributes to ATP hydrolysis activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to nitric oxide; and response to muscle activity. Located in several cellular components, including cell surface; membrane raft; and mitochondrial inner membrane. Part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Used to study non-alcoholic fatty liver disease and pulmonary hypertension. Biomarker of Alzheimer's disease and hypertension. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 22 and mitochondrial complex V (ATP synthase) deficiency nuclear type 4. Orthologous to human ATP5F1A (ATP synthase F1 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Atp5f1a

Retroname	Coord	Strand	Genomic Region	ENSG
Atp5a1P1	chr7:45966648-45966924	+	Intergenic	N/A	UCSC

Expression

Transcript Sequences

>NM_023093.1

GTCGTCCGGAGGCTGCGGCTGCAGAAGATCTCTCCAAGAAGCTGCAAGGATGCTGTCCGTGCGCATCGCCGCGGCCGTGGCCCGTGCCCTCCCTCGACGGGCGGGACTGGTCTCCAAAAATGCCTTGGGGTCATCTTTTGTTGGTACAAGAAATCTCCATGCCTCTAACACTCGACTTCAGAAGACTGGCACTGCCGAGATGTCCTCCATTCTCGAGGAGCGGATCCTTGGAGCTGATACTTCTGTTGACCTTGAAGAGACTGGCCGTGTCTTAAGCATTGGTGATGGTATTGCCCGAGTGCATGGACTGAGGAACGTTCAAGCTGAGGAGATGGTAGAGTTTTCTTCCGGCTTAAAGGGTATGTCCCTGAACTTGGAACCCGACAATGTTGGAGTTGTCGTGTTTGGGAATGACAAGCTAATTAAAGAAGGTGATATCGTGAAGAGAACAGGAGCCATCGTGGACGTTCCAGTTGGCGATGAACTGTTGGGCCGTGTAGTTGATGCCCTGGGAAATGCCATTGATGGGAAGGGTCCAGTTGGTTCCAAGATTCGCAGACGAGTGGGCCTGAAAGCCCCTGGAATTATCCCCCGAATCTCTGTGCGGGAACCAATGCAGACGGGCATCAAGGCTGTGGATAGCCTGGTGCCGATTGGCCGAGGTCAGCGTGAGCTGATTATTGGAGACAGACAGACCGGGAAAACCTCGATTGCTATTGACACAATCATCAACCAGAAGCGTTTCAATGATGGGACTGACGAGAAGAAGAAACTGTACTGCATCTACGTTGCTATTGGTCAGAAACGGTCCACCGTTGCTCAGTTGGTGAAGAGACTGACAGACGCAGATGCCATGAAGTACACCATTGTGGTGTCAGCCACTGCCTCTGATGCTGCCCCGCTTCAGTACTTGGCTCCTTACTCCGGCTGCTCCATGGGAGAGTATTTCCGAGATAATGGCAAGCACGCTCTGATCATCTATGACGACTTATCCAAGCAGGCTGTTGCTTACCGCCAGATGTCTCTGCTGCTCCGCCGACCCCCGGGTCGAGAGGCCTATCCCGGTGATGTGTTTTACCTACACTCTCGCCTGCTGGAGAGAGCAGCCAAGATGAACGATTCCTTTGGTGGTGGCTCTTTGACTGCCTTACCAGTCATTGAAACACAGGCTGGTGATGTGTCCGCCTACATTCCAACAAACGTTATTTCCATCACCGATGGACAGATCTTCTTGGAAACAGAATTGTTCTATAAAGGCATCCGCCCTGCCATTAATGTGGGCTTGTCTGTGTCCCGTGTCGGATCTGCCGCCCAGACCAGAGCCATGAAGCAGGTGGCAGGCACCATGAAGCTGGAGTTGGCCCAGTACCGGGAGGTCGCTGCTTTTGCCCAGTTTGGTTCTGATCTGGATGCTGCCACTCAGCAGCTCTTGAGCCGTGGCGTGCGCCTGACCGAGCTGCTAAAGCAAGGACAGTACTCTCCCATGGCTATTGAAGAACAGGTGGCTGTCATCTATGCAGGCGTCCGGGGTTATCTTGATAAACTGGAGCCCAGTAAGATCACAAAGTTCGAGAGTGCTTTCTTGTCTCATGTTGTGAGCCAGCACCAGAGCCTCTTGGGCAATATCAGGTCTGATGGGAAAATCTCAGAACAGTCGGATGCAAAGCTGAAGGAAATCGTAACAAACTTCTTGGCTGGGTTTGAACGGTAAAGCCCTGCCACTGTCACCAGAAACTGCATTTGGGATTTGTCATTTATTGCGGTAAAATCAGCCACCATTTGTACAAGGGAGTTTACCTTGTACTCCTGATGTACAGAAATACATTTGAATTCAAAAGTTCCATATTG