Summary

Gene Name	Ifitm3
Specie	Mus musculus
Full Name	interferon induced transmembrane protein 3
Also known as	1110004C05Rik|Cd225|Cdw217|DSPA2b|Fgls|IP15|mil-1
Coordinate	chr7:140589503-140590657
Strand	-
Gene summary	Involved in negative regulation of viral entry into host cell and response to virus. Acts upstream of or within defense response to other organism; negative regulation of cell population proliferation; and receptor-mediated endocytosis. Located in several cellular components, including apical part of cell; cell surface; and endoplasmic reticulum. Is expressed in several structures, including alimentary system; egg cylinder; embryo ectoderm; genitourinary system; and mesenchyme derived from lateral plate. Human ortholog(s) of this gene implicated in COVID-19; adenosquamous gallbladder carcinoma; and gallbladder adenocarcinoma. Orthologous to several human genes including IFITM3 (interferon induced transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Ifitm3

Retroname	Coord	Strand	Genomic Region	ENSG
Ifitm3P2	chr17:66312626-66313217	+	Intragenic	ENSMUSG00000117074	UCSC
Ifitm3P1	chr9:41075630-41076017	+	Intragenic	ENSMUSG00000111337	UCSC

Expression

Transcript Sequences

>NM_025378.2

AGGAAAAGGAAACTTCTGAGAAACCGAAACTGCCGCAGAAAGGGCAGACCCGCAGCGCGCTCCATCCTTTGCCCTTCAGTGCTGCCTTTGCTCCGCACCATGAACCACACTTCTCAAGCCTTCATCACCGCTGCCAGTGGAGGACAGCCCCCAAACTACGAAAGAATCAAGGAAGAATATGAGGTGGCTGAGATGGGGGCACCGCACGGATCGGCTTCTGTCAGAACTACTGTGATCAACATGCCCAGAGAGGTGTCGGTGCCTGACCATGTGGTCTGGTCCCTGTTCAATACACTCTTCATGAACTTCTGCTGCCTGGGCTTCATAGCCTATGCCTACTCCGTGAAGTCTAGGGATCGGAAGATGGTGGGTGATGTGACTGGAGCCCAGGCCTACGCCTCCACTGCTAAGTGCCTGAACATCAGCACCTTGGTCCTCAGCATCCTGATGGTTGTTATCACCATTGTTAGTGTCATCATCATTGTTCTTAACGCTCAAAACCTTCACACTTAATAGAGGATTCCGACTTCCGGTCCTGAAGTGCTTCACCCTCCGCAGCTGCGTCCCTCCTTGCCCCTCCCTACACGCAGGTGTAACACTCATTTATCTATCCACAGTGGATTCAATAAAGTGCACTTGATAACCACC