Summary

Gene Name	Chd8
Specie	Mus musculus
Full Name	chromodomain helicase DNA binding protein 8
Also known as	5830451P18Rik|Chd-8|Duplin|HELSNF1|mKIAA1564
Coordinate	chr14:52435608-52495499
Strand	-
Gene summary	This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which is common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. In mammals, this gene has been shown to function in several processes including transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Knockout of this gene causes early embryonic lethality due to widespread apoptosis. Heterozygous loss of function mutations result in autism spectrum disorder-like behaviors that include increased anxiety, repetitive behavior, and altered social behavior. [provided by RefSeq, Dec 2016]

Retrocopy(s) from Chd8

Retroname	Coord	Strand	Genomic Region	ENSG
Chd8P1	chr16:69986845-69987301	+	Intergenic	ENSMUSG00000116794	UCSC

Expression

Transcript Sequences

>NM_201637.3

GTGCTCCGCCGGAAGGCGCCTTGTTCTCCCGGACGGTGGGTTGCAACTCTTGCCCAGGGAAGGAAGCCGCAGGACTGGCTCAGGAGTTCCATCTTCTCCCGCTGAAGGCTTAGCTGCCTTGCTccatgaagttcaggacaatctgaCATGCACTTGTTTCTTGTCTCTTCATTTGAAGAATAGTCTTCGTCCACtgtgtacattttttttgttaatagggaaggggaggggagaaagagttccccccctccccttccctccccggAACTTCAACAAATACCCTTTATTACTCTACCAAGATGGCAGACCCCATCATGGATCTTTTTGATGACCCAAACTTATTTGGCCTGGACTCTCTGACTGATGACAGCTTTAATCAGGTCACTCAAGACCCCATTGAAGAAGCACTTGGACTGCCAAGCTCTCTGGACTCCTTGGATCAGATGAACCAAGATGGTGGAGGTGGTGATGTGGGGAATTCATCAGCAAGTGACCTGGTTCCTCCACCAGAGGAAACAGCTTCCACTGAACTTCCCAAAGAATccacagctccagctccagaaTCCTTAACCTTGCATGATTATACCACTCAGCCCACCAGCCAGGAGCAGCCAGCCCAGCCTGTCTTGCAGACATCAACACCAACAGCAGGACTCTTGCAGGTCTCCAAGAGCCAGGAGATCTTGAGCCAAGGGAATCCTTTCATGGGTGTCTCTGCCACAGGTGTCTCCCCCAGTAATACTGGAGGACAACCATCTCAGTCAGCTCCTAAGATTGTTATTCTTAAAGCTCCACCAAACTCCTCCGTCACAGGCACCCATGTGGCACAAATTCAGGCCCAAGGTATCACCAGTACAGCTCAGCCCCTAGTGGCTGGGACAGCCAACGGTGGAAAAGTCACTTTTACCAAAGTGCTGACTGGTACACCCCTTCGACCAGGTGTATCCATTGTCTCTGGTAATACAGTGTTGGCCACGAAGGTCCCTGGGAACCAGGCTGCTGTTCAGCGCATTGTCCAGCCAAGCCGACCAGTAAAACAGCTGGTCCTCCAGCCAGTAAAGGGTTCAGCTCCTGCTGGGAATCCTGGGGCTGCCGGGCCCCCACTGAAGCCTGCAGTTACACTGACGTCTACACCTACCCAGGGTGAATCGAAACGCATCACTTTGGTCCTTCAACAGCCACAGTCCGGAGGTCCCCAAGGACATCGGCATGTTGTGTTAGGGAGTCTACCAGGCAAGATAGTGTTACAGGGCAACCAGCTAGCAGCCTTGACTCAAGCCAAGAATGCCCAGGGGCAGCCTGCCAAAGTAGTAACTATTCAGCTGCAGGTGCAGCAGCCACAGCAGAAAATCCAGATTGTACCTCAGCCTCCATCATCACAACCACAGCCACAGCCGCAGCCGCCACCCTCAGCCCAGCCGTTGACCCTGTCCTCTGTGCAGCAGGCTCAGATAATGGGGCCAGGCCAAAACCCAGGGCAGAGACTTTCTGTACCGCTCAAGATGGTGCTGCAGCCACAGGCTGGCTCTTCTCAGGGAGCCTCTTCTGGACTCTCTGTGGTTAAAGTTCTAAGTGCCAGTGAAGTGGCAGCCCTGTCATCCCCAGCAAGCTGTGCCCCTCATACTGCAGGGAAGACTGGGATGGAGGAGAACCGCAGGTTGGAGcaccagaaaaagcaagagaaagcaaatCGGATTGTGGCAGAGGCCATTGCTAGGGCCCGGGCCAGGGGCGAGCAAAACATACCTCGAGTCCTGAATGAGGATGAGCTGCCTAGTGTCCGGCCAGAGGAGGAGGGTGAAAAGAAACGCAGGAAGAAGAGCAGTGGGGAAAGGCTGAAGGAGGAGAAGCCAAAGAAGAGCAAGACTGCTGCTGCCTCCAAAACGAAGGGCAAGAGTAAGCTAAACACCATCACTCCTGTAGTGGGCAAGAAGAGAAAGCGTAACACATCGTCTGACAACTCTGACGTGGAAGTTATGCCTGCACAATCGCCCCGGGAGGACGAAGAGAGCAGCATCCAGAAGAGACGTTCAAACCGCCAAGTTAAGCGAAAAAAatatacagaggacctggatATAAAGATAACAGacgatgaagaggaggaggaggtcgaTGTAACTGGTCCAATAAAACCCGAGCCCATCCTCCCAGAACCAGTGCAAGAGCCTGATGGCGAGACTCTTCCTTCCATGCAGTTCTTTGTGGAGAATCCTAGTGAAGAAGATGCAGCTATTGTGGACAAAGTGCTTTCCATGCGAGTTGTGAAGAAAGAGCTTCCTTCTGGACAATACACTGAGGCTGAAGAATTCTTCGTCAAGTACAAGAACTACTCTTATCTGCACTGTGAGTGGGCAACGATCTCCCAGCTGGAGAAGGATAAGAGGATCCACCAGAAACTAAAACGGTTCAAAACAAAAATGGCTCAGATGAGACACTTCTTTCATGAAGATGAAGAGCCTTTCAATCCAGACTACGTAGAGGTGGATAGGATACTGGACGAGTCTCACAGTGTTGACAAGGATAATGGTGAGCCTGTAATTTACTACCTGGTAAAATGGTGCTCTCTGCCCTATGAGGACAGTACGTGGGAGCTAAAAGAGGATGTTGATGAGGGCAAGATTCGGGAATTTAAACGGATCCAGTCAAGGCACCCAGAACTGAGAAGGGTGAATCGTCCACAGGCAAATGCCTGGAAGAAATTGGAGTTATCACatgaatataaaaacagaaaccaattACGGGAATATCAGTTAGAAGGGGTCAACTGGCTCCTCTTTAATTGGTATAACAGGCAGAACTGCATCCTGGCTGATGAAATGGGATTGGGCAAAACTATTCAGTCAATCGCCTTCTTGCAGGAGGTATATAATGTAGGCATCCATGGTCCCTTTTTGGTCATTGCTCCATTGTCCACCATTACTAACTGGGAGCGTGAATTCAATACATGGACAGAGATGAACACTATTGTGTACCATGGCAGCCTGGCCAGCCGGCAGATGATCCAGCAGTATGAAATGTACTGTAAAGACTCACGGGGTCGCCTCATCCCTGGTGCATATAAGTTTGATGCCTTGATCACCACTTTTGAGATGATTTTGTCAGACTGTCCTGAGCTTCGTGAAATTGAATGGCGTTGTGTTATCATTGATGAAGCCCATAGGCTGAAGAACCGTAATTGCAAGCTACTTGATAGTCTCAAGCACATGGACCTGGAGCATAAAGTGTTACTCACAGGGACACCGTTACAAAATACCGTAGAGGAACTGTTCAGTCTACTGCATTTCTTGGAACCTTCTCAGTTCCCCTCAGAATCAGAATTCCTTAAGGATTTTGGGGATCTCAAGACCGAGGAGCAGGTTCAAAAGCTTCAGGCCATTCTAAAGCCAATGATGCTGAGGAGACTCAAAGAGGATGTTGAAAAAAATTTGGCTCCCAAACAGGAAACTATTATTGAAGTAGAGCTAACCAACATCCAGAAGAAATACTACAGAGCTATTTTAGAGAAgaatttctccttcctttccaaagGGGCAGGTCATACCAATATGCCTAATCTACTGAACACAATGATGGAGCTACGAAAGTGCTGCAATCACCCGTACCTCATCAATGGTGCAGAAGAGAAAATCCTGATGGAATTTCGGGAAGCTTGCCATATTATACCTCAAGATTTCCACCTGCAGGCTATGGTTCGGTCAGCTGGCAAGTTAGTTCTCATTGACAAGTTACTTCCAAAGCTTAAAGCTGGTGGCCATAAAGTTCTGATCTTCTCCCAGATGGTACGCTGTCTAGACATTCTGGAGGATTATCTGATCCAGAGGAGGTACTTATATGAACGTATTGATGGGCGAGTTAGAGGCAACCTTCGACAAGCTGCTATCGACCGCTTTAGCAAGCCTGACTCAGACCGCTTTGTCTTCTTGCTATGTACCCGTGCTGGTGGACTTGGTATTAATCTTACAGCTGCTGATACCTGTATTATCTTTGATTCAGACTGGAATCCACAGAATGACCTGCAGGCCCAAGCACGTTGTCATCGAATTGGACAGAGCAAAGCTGTGAAGGTGTACCGACTCATCACTCGTAATTCCTATGAGAGAGAGATGTTTGATAAAGCTAGCCTCAAGTTGGGATTGGATAAAGCTGTGCTTCAGTCCATGAGTGGTCGGGATGGCAACATTACTGGAATTCAACAGTTCTCCAAGAAAGAGATTGAAGATCTCTTAAGGAAAGGTGCCTATGCGGCCATAATGGAGGAAGACGATGAGGGTTCTAAGTTTTGTGAGGAGGACATAGATCAGATCTTACTGAGACGGACCACAACCATCACTATTGAGTCTGAAGGGAAAGGTTCTACTTTTGCCAAGGCAAGCTTTGTTGCTTCTGAAAATAGGACAGATATTTCCCTGGATGATCCAAACTTTTGGCAAAAATGGGCCAAAAAGGCAGACCTAGACATGGATCTGCTGAATAGTAAGAATAACTTAGTGATCGACACACCTCGAGTTCGGAAACAGACTCGACACTTCAGCACTTTGAAAGATGATGACCTGGTTGAGTTTTCTGATTTGGAAAGTGAAGATGATGAACGGCCACGTTCCCGAAGACATGACCGGCATCACACCTATGGGCGCACTGACTGCTTCCGGGTAGAAAAGCATCTCCTGGTATATGGTTGGGGACGTTGGAGAGATATTTTGTCTCACGGACGATTTAAGCGGCGCATGACTGAAAGAGATGTTGAGACAATATGCCGTGCCATCCTCGTGTACTGTCTTCTACACTACCGTGGGGATGAAAACATCAAAAGCTTCATTTGGGACTTGATTAGCCCTGCTGAAAATGGCAAGACAAAAGAATTGCAGAATCATTCAGGTCTGTCTATCCCTGTGCCCCGTGGGCGTaaggggaaaaaagtcaagtcacAAAGTACTTTTGACATTCATAAGGCAGACTGGATCCGGAAATACAACCCTGATACTCTGTTCCAAGATGAGAGTTATAAGAAGCATTTGAAACATCAGTGTAACAAGGTACTGTTGAGAGTCCGGATGCTCTACTACCTGAGACAGGAGGTTATTGGAGACCAGGCAGAGAAGGTGTTAGGAGGTGCCATAGCCAGTGAGATTGACATATGGTTCCCAGTGGTGGATCAGCTGGAGGTTCCTACAACTTGGTGGGATAGTGAGGCTGACAAATCCCTGCTCATTGGCGTTTTTAAGCATGGCTATGAGAAATACAATACCATGAGGGCAGACCCTGCCTTGTGCTTCCTAGAAAAGGCTGGCAGGCCAGATGACAAAGCCATCGCAGCAGAACATAGAGTGTTGGATAATTTCTCCGACCTGGTAGAAGGGATTGACTTTGATAAGGATTGTGAAGATCCTGAATATAAACCCCTCCAGGGTCCTCCAAAGGACCCAGATGATGAGGGTGAtcccttgatgatgatggatgaGGAGATCTCAGTCATCGACGGAGAGGAAGCCCAGGTAACTCAACAGCCAGGGCATTTATTCTGGCCTCCAGGCTCCGCCCTCACAGCTAGGCTTCGCCGCCTAGTAACAGCCTATCAACGCAGCTACAAGAGAGAACAAATGAAGATGGAGGCTGCGGAACGTGGGGACCGGAGACGCCGACGATGTGAAGCAGCCTTTAAGCTCAAAGAAATCGCAAGGCGGGAAAAACAACAACGGTGGACAAGGCGTGAGCAAACTGATTTCTACCGAGTAGTATCTACCTTTGGTGTGGAGTATGACCCTGACAACATGCAGTTTCACTGGGATCGCTTCCGCACTTTTGCTCGCCTGGACAAAAAAACAGATGAAAGCCTTACCAAGTACTTCCATGGTTTTGTGGCCATGTGTCGACAAGTGTGCCGCCTTCCCCCAGCTGCTGGTGATGAACCTCCAGACCCTAATCTGTTCATTGAGCCCATCACTGAAGAGAGAGCCTCGAGGACTCTCTACCGAATTGAGTTGCTTCGACGCTTACGGGAACAAGTTTTATGCCACCCCCTTTTAGAAGATCGGCTGGCATTGTGTCAGCCTCCAGGTCTTGAATTGCCCAAATGGTGGGAACCTGTCCGTCATGATGGGGAGCTCCTACGAGGAGCAGCCCGCCATGGGGTGAGCCAAACAGACTGCAACATCATGCAGGACCCAGACTTCTCTTTTCTGGCTGCCCGTATGAATTATATGCAGAACCATCAGGCGGGAGCATCAGCTGCATCCCTGTCGCGatgctccactccactgctgcacCAGCAGTGTACCTCACGTACTGCTTCACCATCACCCCTGCGCCCAGATGCTCCTGTTGAAAAGTCACCTGAGGAAAGTACTGTTCAGGTCCCCAATCTGGAGAGTCTGACTTTAAAGTTAGAGGATGAGGTTGTGGCTAGGAGCCGACTCACCTCACAAGACTATGAAGTACGCGTAGGCTCTTCAGATACAGCTCCTCTGTCCCGGAGTGTCCCACCAGTGAAACTGGAGGACGAGGATGATTCAGACTCTGAGCTGGACTTGAGCAAGTTGtcaccatcctcctcctcttcttcatcctcgtccagctccagctccagcactGACGAGAGTGAAGACGAGAAGGAAGAGAAGTTAACTGCTGACCGGTCCCGCCCAAAGCTCTATGATGAAGAGAGCCTTCTGTCCCTTACTATGTCCCAAGATGGATTCCCAAATGAAGATGGAGAACAAATGACCCCTGAGTTGCTGCTACTGCAGGAAAGACAAAGAGCCTCTGAATGGCCTAAGGATCGTGTTCTGATAAACCGCATTGACCTCGTCTGCCAGGCTGTACTCTCAGGGAAATGGCCTTCTAACCGCCGGAGCCAGGAAGTGACAGCAGGAGGAATTTTGGGGCCAGGCAACCATTTATTAGACAGTCCCTCTTTGACCCCAGGAGAAGATGGGGACTCTCCAGTCCCCACGCCACGAAGTGGCAGTGCAGCTTCCATGGCGGAGGAAGAGGCATCTGCAGTCACCACAGCGGCGGCCCAGTTTACGAAACTTCGGCGAGGCATGGATGAGAAAGAGTTTACAGTTCAGATCAAAGATGAAGAAGGATTGAAGTTAACATTCCAGAAGCATAGATTGATGGCTAATGGTGTAATGGGAGATGGACATCCACTGTTTCATAAGAAGAAGGGGAACAGGAAAAAGCTAGTAGAGCTGGAGGTGGAGTGCATGGAAGAGCCTAATCACCTTGATCTGGACCTGGAGACCCGGATCCCTGTCATCAATAAGGTGGATGGTACTTTGCTGGTGGGTGATGAGGCCCCTCGCCGGGCGGAGCTGGAGATGTGGTTACAGGGTCATCCAGAGTTTGCTGTTGATCCCCGATTTCTAGCGTATATGGAGGAACGTAGAAAACAGAAGTGGCAgagatgtaaaaaaaataataaggcaGAATTGAACTGTTTGGGAATGGAACCAGTACAGCCAGCGAACTCTAGAAATGGGAAAAAGGGTCACTATGCTGAAACTGCGTTCAACCGGGTTTTGCCAGGGCCTGTTGCACCAGAGAACAGCAAGAAACGGGTCCGTAGGACAAGACCAGACCTTTCTAAGATGATGGCCCTGATGCAGGGTGGAAGCACTGGGTCCCTGTCTCTGCATAACACCTTTCAACACAGCAGTAGTAACCTACAGTCTGTGTCGTCTCTGGGTCACAGCAGTACCACTTCTGCATCTCTGCCTTTTATGCCGTTTGTGATGGGTGCAGCAGCACCCCCTCATGTagactccagcaccatgcttcatcatcaccaccaccatccccacccccaccatcaccaccatcaccatccaggcttgagaaccactggctacCCTTCTTCACCAGCTACTACCACCTCTGGTACTGCCTTGCGGTTACCAACACTGCAACCTGAGGACGATGatgaagaggaggatgaagaagatgatgatttATCTCAGGGCTATGACAGCTCAGAACGGGACTTCTCACTCATTGATGACCCTATGATGCCAGCCAACTCAGACTCCAGTGAAGATGCTGACGACTGAAGCCCCATATAGACCCGTGATGGGTGGCTGCTGGAATCCCTTACTCTGGCCCTTGGACTTTGGAAATGTGGGAGGGGCAGGGAACAATATGGGGAAACCCAAGACTTCAGGaggtgaaaagaaaaagaaaaaaacaaaaaacaaaaaaaaacaaaaaacttgtaccCAATTGCTCCCAATTTTGAGAGGATTGGGTGGGCAGGGgaactcctaaaaaaaaaaaataataaatgaccaCTTCCTCGTTTCTGGGGAAGCAAAGGAGCTTAGAGCAGCTGGTGTGCTCACCCCTCCCCAGACGCCTCCATTAACCACAGACTATGTAGCGCTGGCCCTAGCCTCTGGCAGAGCCTGTTCCTGGCCAAACTGTGGCTACAGCTGGAGGGTCAGGAACTGTTACCTTCCTTCCCCTTGGCATTAATAAATTTAAGTTAATCCTTT