Summary

Gene Name	Afg3l2
Specie	Mus musculus
Full Name	AFG3-like AAA ATPase 2
Also known as	2310036I02Rik|Emv66|par
Coordinate	chr18:67537830-67582277
Strand	-
Gene summary	Predicted to enable metalloendopeptidase activity. Involved in protein autoprocessing. Acts upstream of or within several processes, including mitochondrion organization; nervous system development; and righting reflex. Located in mitochondrial inner membrane. Part of m-AAA complex. Is expressed in brain. Used to study spinocerebellar ataxia type 28. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia; spastic ataxia 5; and spinocerebellar ataxia type 28. Orthologous to human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Afg3l2

Retroname	Coord	Strand	Genomic Region	ENSG
Afg3l2P1	chrX:90328584-90328867	-	Intragenic	N/A	UCSC

Expression

Transcript Sequences

>NM_027130.2

GTCCGCACGCTGGGGCGGAGCCTGGCGAGCACGCGTGGAGCGTGGGTTCGCGTTCTGTCGCGGGTCTCCTGCGCCGGTGGCGCGCAGTTTCCGAAGAACCGATAAGCTGCGGAAGCCGCGAAAGCTGCGGGCCGCCGATCGCCCGCCTCGGCTCCGTGCCTGCGCGCGCCCCAGAGCGGGCCGGGCCCACCATGGCCCACCGCTGCCTGCTGCTGTGGAGCCGGGGCGGCTGCCGTCGCGGCCTTCCTCCCCTGCTCGTGCCCAGAGGTTGCCTGGGTCCGGACCGGCGGCCCTGCCTCCGTACGCTCTATCAATATGCTACTGTCCAGACAGCAAGCAGCAGGCGTTCTCTGCTGAGGGATGTAATTGCTGCTTATCAAAGATTCTGTTCTCGACCTCCCAAAGGATTTGAAAAGTACTTTCCTAATGGGAAAAACGGAAAAAAGGCCAGTGAGCCTAAGGAGGCTGTTGGAGAAAAAAAAGaACCACAGCCCTCGGGCCCCCAGCCTTCTGGAGGTGCaggtggtgggggagggaagcGCCGTGGCAAGAAAGAAGATTCTCACTGGTGGTCCAGGTTCCAGAAGGGTGACTTCCCATGGGATGACAAGGATTTCAGGATGTACTTTCTCTGGACTGCTCTTTTTTGGGGTGGAGTCATGATTTACTTCGTGTTCAAGAGCTCTGGGAGAGAAATCACGTGGAAAGACTTTGTCAATAACTATCTTTCTAAGGGCGTGGTGGACAGACTAGAAGTTGTCAACAAGCGTTTTGTTCGTGTGACCTTTACACCAGGAAAAACTCCGGTTGATGggcaATACGTCTGGTTTAATATTGGCAGTGTTGACACATTTGAGCGGAATCTGGAGACTTTGCAGCAAGAATTGGGCATAGAAGGGGAGAACCGGGTCCCTGTGGTTTATATTGCTGAGAGCGATGGctccttcctgcTGAGCATGTTGCCCACCGTACTCATTATCGCTTTTCTACTCTACACCATAAGAAGAGGGCCCGCTGGCATTGGTCGGACCGGCCGGGGAATGGGTGGACTCTTCAGCGTTGGGGAAACCACAGCCAAGGTCTTAAAGGATGAGATAGATGTGAAGTTTAAAGATGTGGCTGGCTGTGAGGAGGCCAAGCTAGAAATAATGGAATTCGTGAATTTCTTGAAAAACCCAAAGCAATATCAAGACCTAGGAGCAAAAATcccaaagGGTGCCATTCTCACCGGTCCCCCAGGTACTGGGAAGACGCTGCTAGCTAAGGCCACAGCTGGAGAAGCCAATGTCCCCTTTATCACTGTGAGCGGATCTGAGTTTCTGGAGATGTTTGTTGGCGTTGGTCCAGCCAGAGTCCGAGACTTATTTGCCCTTGCTCGGAAGAATGCGCCTTGCATTCTCTTCATTGATGAGATTGATGCTGTGGGAAGGAAGCGCGGCAGAGGCAACTTCGGTGGGCAGAGCGAGCAGGAGAACACACTCAACCAGCTGCTTGTGGAGATGGACGGCTTCAACACAACCACCAATGTGGTCATCCTGGCAGGCACAAATCGACCAGACATCCTGGATCCAGCTCTGTTGAGACCAGGCCGCTTTGACAGGCAGATTTTTATTGgaCCCCCAGACATAAAAGGACGAGCCTCAATCTTCAAAGTTCACCTTCGACCATTGAAGCTGGACAGTGCCTTGGAAAAAGATAAATTGGCCAGAAAACTGGCGTCCTTAACTCCAGGGTTTTCAGGCGCTGATGTTGCCAATGTCTGCAATGAAGCTGCTTTGATTGCTGCAAGACACCTTTCAGATGCCATTAATGAGAAGCACTTCGAACAAGCGATTGAGCGAGTGATTGGAGGCTTGGAGAAAAAAACCCAAGTTCTGCAGCCTGAGGAGAAGAAGACGGTGGCTTACCACGAAGCAGGCCATGCGGTCGCTGGCTGGTATCTGGAGCATGCAGACCCACTCTTAAAGGTCTCCATCATCCCGCGTGGCAAGGGGCTGGGCTATGCTCAGTACTTGCCCAAGGAGCAGTATCTGTACACAAAGGAGCAGCTGCTGGACAGGATGTGCATGACTCTGGGCGGCCGTGTCTCCGAGGAGATCTTCTTTGGGAGAATTACAACCGGTGCCCAGGACGACTTGAGGAAGGTTACCCAGAGTGCCTATGCCCAGATCGTTCAGTTTGGCATGAACGAGAAAGTGGGGCAGATCTCCTTTGACCTCCCACGACAGGGGGACATGGTGTTAGAGAAGCCTTACAGTGAGGCCACTGCGAGGATGATAGACGATGAAGTGAGGATACTCATCAGCGATGCCTACAGAAGGACGGTGGCTCTTCTCACAGAGAAGAAGGCTGACGTGGAGAAGGTCGCTCTCTTACTGTTAGAAAAGGAAGTCCTAGACAAGAATGACATGGTCCAGCTTCTCGGTCCCAGACCATTTACAGAAAAGTCCACATATGAAGAATTTGTGGAAGGCACTGGCAGCTTAGACGAGGACACTTCTCTTCCTGAAGGCCTTCAGGATTGGAACAAGGAgcgggagaaggaggagaagaaggagaaggagaaggaggagccgCTGAATGAGAAGGTTGTCAGCTAGGCCAGGACCTGCAGGCCCCTTTCCTTTGTCCTCCCAGGGCTTCAGTCTGAACAAGGGCCCTGCTGCAGAGCCGGCCGTCGAGTCAGCCAGGCGGAGGGGATGGCCTCCATTGCAGCTGAGGGCTTCACAACTGCAGCAACTGCCAGGGGCTGGGAAGGAGACTTCCTCAGCCTTGCCCTCATGAACAGCGGCTGGAACAGGagagacagcaccacctgccgaGGCCTGTCCCGTGGAATCCTGTCCCGTGGGAGAAGACTTTTCCTACCACCCTCTCGTCATTCCTCCTGTGACATCTCTGCAGACGTGCTGTGAAATTCAGTTGGAGTCCTAATAAGAATATTTTGATTCAaccaaatattttcaaatttgaatTCAGATCACTTGTTGCTGTTTTAATGGAATGGTTTTCTATAGAGAACTGTACcatatttaaaaacatgaatgtattatataaatatgGAGTCTTTATATCAGAAATAAAGGTGGACATTGCACTTTTTTCCTGAGCATA