| Gene Name | TSN |
|
| Specie | Homo sapiens | |
| Full Name | translin | |
| Also known as | BCLF-1|C3PO|RCHF1|REHF-1|TBRBP|TRSLN | |
| Coordinate | chr2:121755651-121767853 | |
| Strand | + | |
| Gene summary | This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| TSNP1 | chr7:93777852-93778358 | + |
Intergenic |
ENSG00000225898 | UCSC |
| >NM_004622.3 |
| GGTCGTGGCGTAAGACCGGGGGGACGCGGCGGTAGCGGCGGCCGTTGCGATTGATTGCGCTGGTTGCCTGCGGCGTCCACTTCCTTGGCCGCCCTTGCTACACTGGCTGATTGTTGTGCAGCCGGCGCCATGTCTGTGAGCGAGATCTTCGTGGAGCTGCAGGGCTTTTTGGCTGCCGAGCAGGACATCCGAGAGGAAATCAGAAAAGTTGTACAGAGTTTAGAACAAACAGCTCGAGAGATTTTAACTCTACTGCAAGGGGTCCATCAGGGTGCTGGGTTTCAGGACATTCCAAAGAGGTGTTTGAAAGCTCGAGAACATTTTGGTACAGTAAAAACACATCTAACATCTTTGAAGACCAAATTTCCTGCTGAACAGTATTACAGATTTCATGAGCACTGGAGGTTTGTGTTGCAGCGCTTGGTCTTCTTGGCAGCATTTGTTGTGTATTTGGAAACAGAAACACTAGTGACTCGAGAAGCAGTTACAGAAATTCTTGGCATTGAGCCAGATCGGGAGAAAGGATTTCATCTGGATGTAGAAGATTATCTCTCAGGAGTTCTAATTCTTGCCAGTGAACTGTCGAGGCTGTCTGTCAACAGCGTGACTGCTGGAGACTACTCCCGACCCCTCCACATCTCCACCTTCATCAATGAGCTGGATTCCGGTTTTCGCCTTCTCAACCTGAAAAATGACTCCCTGAGGAAGCGCTACGACGGATTGAAATATGACGTGAAGAAAGTAGAGGAAGTGGTCTATGATCTCTCCATCCGGGGCTTTAATAAGGAGACGGCAGCAGCTTGTGTTGAAAAATAGGAGGCTCTCCTTGCTCCTGGCCTTGCTGACCTCAGCGGTTGCCAGGAAGGGGTGAGCACAGAGTGCCTCTTACGGTAGTTAGGATGCTCAGTTGCTAAACACTGCGCTTTATTTTCTTAACCAGTTGTGGTGTGAGTATCAGAATTGAAACACTTTTTTGGGGGTAAAAAATATAGCCTTTACATGGACAGAATTTTTTTTGTTGTTTCAGTGAATATGCCTGTAATTCAGTGTATTTCAGTTCCGTCAGAAAGTGTAAATGTTAGTTTCTTGGTAAAGTCCTTTTCTTGCTTACCTTGACTGTTGATGTACTGATTGAGAAGTTCATTGTCTCGTTTGTGATTCTTCCAGATGTGATGCTTGATATTTTCTATATGCGAGTTAGCCATCCACACCCAGGCATAGCCTGGATACAGTATAAAAATAGATAATTAAAAAGATGGTTGCCAAGCAAGGAAAACTTATTTTATATTTTCCCTTCCTTATTTTAAGCATTGTGAGTAAATCAGATGTTGAATTCTTTTGCCAAGGGAATTATAGCTGCAGGTTCTCTCTCACTGCCATCAAACTGTAAAAGATTAAACTGCGAAGTCAAGCTCAACAGATTATTTTGGAAAGTTTTTGTATTAAGGGATTTAGTAACATCATTTTGTTTTCCACCAGGCAGGGAGTAGGGCTTAGTGTTTTAAAACACCTCTGCTTTCTGATGTTGCCTTAATATTCTGCTATTGCAGCAATTAAAAATTGTCTTCATGTACATTTGGAACTAACACGTGATGTGATATATTCCTAAACTATGAAACCTTTTTCCTAGTAGTCAGCTAGATCATTTGTTCTGGGAGTATAAAGCCACCCACGTAAGTTAATAAGCAAAATCCTGACTATTATGTTGTTAGAGAAAAATGCTTTGCTTTGTCTGGAAGAAAGATAAAATAGTGAATTATAAATAAGTCAggccgggcgtggtggctcacacctgtaatcccagcacactgggaggccgaggcagggggactgcttgagctcaggagttcgagaccagcctgggcaacaaagtgagactccatctctatataaaaacaaaaaCCACGAAAGCACACACAAAATAAATCAGTGGGATTTGGTAATGTGTTTTAGAGTAAGAAATTTCAGGTTGTTGGTGACTATCCCAACAGTCATGTTTTAAATGTACAGTTTGGGGCAAGTCATGTAAATACTGTTGGTGGTCTTCCCCACACGCCCCAATTTTCAGGTAGTACTAAGAGTATGTGCCAGGAAACTCTTGCTATTGAATTGAGATGATTAAAATGGTGACTTAATCCGTAGTTATTTTGCACCCACTGAAAGGAAAGTGCTTTCCAGAATAATATGAAGTATCTAAAAGTGTCACCTTTTCTTGCCTGATCAACAATTTGGGCTTCCTGTTTGTACAAGGGGCCATTTGGCATACCTTTCACAGCTTTTATCAGGCCAAGTTAAAGGCTGACTACATTTTTTCATCATGAGGAAAGCAGTTGAAATGAGGCATGAGTTACTGTGCATTGGGATTTTAGAACAATTTTCTTGTGACAGCTCTTTTTGTGAAGTTAGGTTCTTAAAAGTGCCCATGATGGTCACTTAAAATGTGCAGTAATAGCACTGCCAGGATCAAGCATGAAAGGCTTTTAAATTAGATCATCCCACAGACAATACGTTTGATAATAGTTTTTTCTTTTAACCTCTTTAAGTATTGATTCTGCTTGAGAATATTGAAGTACTTGCCAGAAGTTGTGGATTTCAGTTTTAACAAATGCTATTAAAGTGGAGAAGCACACTCTGGTCTTGGAATTCCATTTGAGGATTTAGAAGTGTCATGTTTATAACTATTCAGTTGTGTTTGTTGCTGGCTTGTTGTAAAGCAATAAAATTTTTTTGGTCTTTTTGTAAGTGAGTGTGCTGCTGTAAGAAATCTCCCATGTGCATAACAAATTCTGAATATTTTTTGAGGCTAAAGAAGACCGGGGTGACAAGCAGATACTGCTGTGTAATGGTTACACTAACCAAAAGACACCAGCCACTCAGAGTTCTATACTGTAAAGCGCAGATAACATTTGTGTGTTATACCTTGATTGGGGAATTAAAAGTCATTTAACTGAAGATGTTGAGAAACCTGGGCTCTGGTTTTAGTATACCGGAATTACTTTTTTCCAATTTTAGAAAATCAAGCAGGTTAGAGAAAATAGAGATGAATTAGGGGACACTGTCTTATGGATTCATTTATAAGAAGAGAACCAGCCATATACACTTGGGGAGATTTGCCACATCTTAAACTTGAATAATAGTATGAGTAATGCTTAAGGGAGTTTAATAGAGAAGGAAAGCTTTGGCAGTGTTTTGAGAACTTAAGTGGCTAAAGAGATGAGACAAACATGCAGGTCGCTACTGGCATAGTTTCATAATTGTGTACTCGGAAATTAAAGTTTGCTTGTTTCTTGGTCTGGATTAAA |