Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name UBE2D2
Plot displaying the genomic locations of a parental gene (in chr5) and its retrocopy(ies). Each line represents a retrocopy.
Specie Homo sapiens
Full Name ubiquitin conjugating enzyme E2 D2
Also known as E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B
Coordinate chr5:139561286-139628434
Strand +
Gene summary Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

Retrocopy(s) from UBE2D2

Retroname Coord Strand Genomic Region ENSG
UBE2D2P1 chr6:25181290-25182628 + Intergenic
 ENSG00000217805 UCSC

Expression

Transcript Sequences

>NM_003339.3
GGCCCCACCCCGGCGGCGCAGCCCGCCCGCCCGCGCGTCCCTCGGTCCACCTGCAGCAGGGAGGAAGACAGGCAATCCCTCCGGCTGTCCGACCAAGAGAGGCCGGCCGAGCCCGAGGCTTGGGCTTTTGCTTTCTGGCGGAGGGATCTGCGGCGGTTTAGGAGGCGGCGCTGATCCTGGGAGGAAGAggcagctacggcggcggcggcggtggcggctagggcggcggcgAATAAAGGGGCCGCCGCCGGGTGATGCGGTGACCGCTGCGGCAGGCCCAGGAGCTGAGTGGGCCCCGGCCCTCAGCCCGTCCCGCCGGACCCGCTTTCCTCAACTCTCCATCTTCTCCTGCCGACCGAGATCGCCGAGGCGGCCTCAGGCTCCCTAGccccttccccgtcccttccccgcccccgtccccgccccgggggccgccgccacccgcctcccACCATGGCTCTGAAGAGAATCCACAAGGAATTGAATGATCTGGCACGGGACCCTCCAGCACAGTGTTCAGCAGGTCCTGTTGGAGATGATATGTTCCATTGGCAAGCTACAATAATGGGGCCAAATGACAGTCCCTATCAGGGTGGAGTATTTTTCTTGACAATTCATTTCCCAACAGATTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTTGATATTCTACGATCACAGTGGTCTCCAGCACTAACTATTTCAAAAGTACTCTTGTCCATCTGTTCTCTGTTGTGTGATCCCAATCCAGATGATCCTTTAGTGCCTGAGATTGCTCGGATCTACAAAACAGATAGAGAAAAGTACAACAGAATAGCTCGGGAATGGACTCAGAAGTATGCGATGTAATTAAAGAAATTATTGGATAACCTCTACAAATAAAGATAGGGGAACTCTGAAAGAGAAAGTCCTTTTGATTTCCATTTGACTGCTTTCTATGAGCCCACGCCTCATCTTCCCCTGTGCACATGTTTACCTGATACAGCAGTGCTGCGTGTTGTACATACTTGGAACAACAAACTAGAAATACTGTACTTCTGTACCAACATTGCCTCCTAGCAGAGAAGTGTGTGTGTGACAAGCCAGTTCTACAGGCATTACCTAGGTGTGAGACTAAAAGCTTTTCTTATTGACTTAAATTTGGATAACAGCAAGGTGTGAGGGGGGTGGTGGGTATGGTGTGTGCTTGGATGGGAAAGAAAAGGCTCCACTCACCTATAGGAGATTATTTTTAAGTGGAATCCATTTAAACTCAAAACAGTTATGAAAAGCAAGGTGAAGAACATGAAGCTGTGTCTGTATTCATTTTATTCCGAAGGAGCTACGTCTTAGGTGAAAGTTATGACCAACCAGATTAAACTCTACCCACATCCTGCATTTTAAGGTCTAAGTTTAACTGGTCAACATTTAAATGGATTGGAGCTATTAGTACATCAAGTGTGATGGGCTTTGTTCCCAACTCTTTTACATCTCCCTACCCCTTCAACCTTTGGCCTTTCAGCCCTTCTTTCTCTCTTCCATATTCTTTGGTTTGTATGTGGTTTCTCAGTTAATACATAGCTAATAGCTCTTATTTTTCTTATGTTTTTAACCGCTTAGGTCTATTTGGATGTAAGGGTGAAAATTCATTTGATGGAAATACTTGTGTATATTTAAAGACCCAATTGCTCCTCTGGAGCTTGTACTTTCAAGAATGATTAATCTGTGTAATAAACTGGTTACTACAGTCATTACATATAATTTTGTGTGAATAGGCTTTTTCATTTTTAAGAAGTTTGTCTAGCTGAGATTAGTGGTGGATTTTCTCCCACTTCTGAAATGTTCATTTATACTGGTTGCATTTTAAGATCATGAAACAATTCCAGTTACATTGTAAAAAGGATATCTTACGAGTAATTTTATTGAACAAGTTAGAGGCATAAGCTTAAGAGCATTTCCATGAAACAACACATGCAGCATTCCAGGAACTTGATTGTTAAATTCAATAAGAAATTTGCTTTATTAATGAAACTAAGCTGCATTTCATCAAAACCTTGTGACATTCCCTTGGTACATAGGACATAAAACACAGAGGCATTGCTATTTGGTAAGTTAAGCTTCTGTGATTGTAATTATAAAAGAGCAACATTGACCAAACCTGGGAAACAAGAGCACAGTCTTGTTTGGAGAGTCTACATAATTACTTTGCACTAACATTTGCAGGATGTTCACACAATTTTAAATTGTACTGTATGTGGCTTTTTGAAGTCTTCCCTTGACCCTAGTAAAATATAGCTTGAAACTTGTAAACAACTGTGTTTGCCAGAAACATCATTCATGTGAACTAGGCAAGTTACCTTTTTTCCCCCCTTCTTTTCCTAATTGTAAACTAGGCCAACCTGAAAGCCATGGCTGATGCTCTAGCCATCAGGTTCTTTCAAATGCATCTTTACACTCTTGCACAAAAGTTAAGGAATAAATGTCCACTGCTTTTGGTTTTAAA