Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Gene Name Apex1
Plot displaying the genomic locations of a parental gene (in chr15) and its retrocopy(ies). Each line represents a retrocopy.
Specie Rattus norvegicus
Full Name apurinic/apyrimidinic endodeoxyribonuclease 1
Also known as APE|Apex|REF-1
Coordinate chr15:27849943-27852083
Strand +
Gene summary Enables NF-kappaB binding activity and endoribonuclease activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of smooth muscle cell migration; and positive regulation of G1/S transition of mitotic cell cycle. Located in mitochondrion and nucleus. Part of transcription regulator complex. Biomarker of brain ischemia; lung disease; status epilepticus; and visual epilepsy. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Retrocopy(s) from Apex1

Retroname Coord Strand Genomic Region ENSG
Apex1P1 chr4:13040251-13041306 - Intergenic
 N/A UCSC
Apex1P2 chr4:16748003-16749058 - Intragenic
 N/A UCSC
Apex1P3 chr7:141797613-141798518 - Intragenic
 N/A UCSC
Apex1P4 chr14:42236023-42236190 + Intergenic
 N/A UCSC

Expression

Transcript Sequences

>NM_024148.1
AGACAGACTCCATTCTTTGTGCAGTGAGGGGCTCCCTGCCTCGTTGGGAGGCAGCGTAGTAAACACTGCTTCGGTGCTCCAGACGCCTAAGGGCTTTCGTTACAGCGATGCCGAAGCGGGGGAAGAGAGCGGCAGCGGAAGACGGGGAAGAACCCAAGTCCGAGCCAGAGACCAAGAAGAGTAAGGGGGCAGCAAAGAAAACTGAGAAGGAGGCCGCAGGAGAGGGCCCTGTCCTGTATGAGGACCCTCCAGATCAGAAAACGTCAGCCAGTGGCAAATCTGCCACACTCAAGATATGCTCCTGGAATGTGGATGGGCTTCGAGCCTGGATTAAAAAGAAAGGCTTGGATTGGGTAAAGGAAGAAGCACCAGACATCTTGTGCCTCCAAGAGACCAAATGCTCAGAGAACAAACTCCCGGCTGAACTGCAAGAGCTGCCTGGACTCACCCATCAGTACTGGTCAGCTCCATCAGACAAAGAAGGATATAGTGGTGTGGGCCTACTTTCCCGCCAATGCCCGCTCAAAGTCTCTTATGGCATTGGTGAGGAAGAACATGATCAAGAAGGCCGGGTGATTGTGGCTGAATTTGAGTCCTTTATCTTGGTAACAGCCTATGTTCCGAACGCAGGAAGGGGTCTGGTAAGACTGGAGTACCGACAGCGATGGGATGAAGCCTTCAGAAAGTTTCTAAAGGACTTGGCTTCCCGGAAACCTCTTGTGCTGTGTGGGGATCTCAATGTGGCTCATGAAGAAATAGACCTTCGTAACCCCAAAGGAAACAAAAAGAATGCTGGTTTTACTCCCCAGGAGCGCCAAGGCTTTGGGGAAATGCTACAGGCTGTACCACTGGCTGACAGCTTCCGGCATCTCTACCCCAACACTGCCTACGCTTATACTTTCTGGACTTACATGATGAATGCCCGCTCTAAGAATGTTGGTTGGCGCCTTGATTACTTTTTGCTGTCTCACTCTCTTTTACCTGCTTTGTGCGACAGCAAGATCCGGTCCAAGGCTCTTGGCAGTGACCACTGTCCCATCACCCTTTACCTAGCACTGTGACACTCCCCTCAAGTAGCTTCATGCTGGGAAATAGCCTCCTCTCCTCCAGGAGACCAGTGCGTTATCTCTTCTTCAGGTGTTTACTCCCCTCTAAACCAAACTTCTGGTTTCCTTTAAACAATCCAAGTGAAATAAAAGTCCTACTTTTCAAC