| Gene Name | PTP4A2 |
|
| Specie | Homo sapiens | |
| Full Name | protein tyrosine phosphatase 4A2 | |
| Also known as | HH13|HH7-2|HU-PP-1|OV-1|PRL-2|PRL2|PTP4A|PTPCAAX2|ptp-IV1a|ptp-IV1b | |
| Coordinate | chr1:31906421-31938368 | |
| Strand | - | |
| Gene summary | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| PTP4A1P2 | chr12:133032905-133034166 | + |
Intergenic |
ENSG00000255807 | UCSC |
| PTP4A2P2 | chr11:134121487-134124987 | - |
Intragenic |
ENSG00000254481 | UCSC |
| PTP4A2P1 | chr17:42532065-42534218 | + |
Intergenic |
ENSG00000267185 | UCSC |
| >NM_001369859.1 |
| GTGTGTGTGGAAGGGAGAGAGCTGTGCGAGCGTGGGGGAGAGTGAGTTGGTGAAGGGAGGGCGTGAGCTTGATCCTGGATAGTGTTTGTATGATGTGCACACGTCTCTGCAAATGCTTGTTTGAAGATTGGCTGTGCTGCATTTTGGTATAATTGGGAGGTGACATATTGTCCCTTATCTCAGTAAACATTTGGAGGAAGAGGACGAGAAAGATTGAATTTTGCATTCTTTAATTGGGAAGAAAAGGAAGGTGAATCCATGTTGAGCTGAGCTAGTTTTTCGTTGGAATATACGTTGCACATTTATGGCGATTCTGAGTGTGAGGGCAGACTTCTGCCAGGCTCAGCACAGCATTTTCGCTGACAAGTGAGCTTGGAGGTTCTATGTGCCATAATTAACATTGCCTTGAAGACTCCTGGACACCGAGACTGGCCTCAGAAATAGTTGGCTTTTTTTTTTTTTAATTGCAAGCATATTTCTTTTAATGACTCCAGTAAAATTAAGCATCAAGTAAACAAGTGGAAAGTGACCTACACTTTTAACTTGTCTCACTAGTGCCTAAATGTAGTAAAGGCTGCTTAAGTTTTGTATGTAGTTGGATTTTTTGGAGTCCGAAGGTATCCATCTGCAGAAATTGAGGCCCAAATTGAATTTGGATTCAAGTGGATTCTAAATACTTTGCTTATCTTGAAGAGAGAAGCTTCATAAGGAATAAACAAGTTGAATAGAGAAAACACTGATTGATAATAGGCATTTTAGTGGTCTTTTTAATGTTTTCTGCTGTGAAACATTTCAAGATTTATTGATTTTTTTTTTTCACTTTCCCCATCACACTCACACGCACGCTCACACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTGGAGATCTCCTATGAGAACATGCGTTTTCTGATAACTCACAACCCTACCAATGCTACTCTCAACAAGTTCACAGAGGAACTTAAGAAGTATGGAGTGACGACTTTGGTTCGAGTTTGTGATGCTACATATGATAAAGCTCCAGTTGAAAAAGAAGGAATCCACGTTCTAGATTGGCCATTTGATGATGGAGCTCCACCCCCTAATCAGATAGTAGATGATTGGTTAAACCTGTTAAAAACCAAATTTCGTGAAGAGCCAGGTTGCTGTGTTGCAGTGCATTGTGTTGCAGGATTGGGAAGGGCACCTGTGCTGGTTGCACTTGCTTTGATTGAATGTGGAATGAAGTACGAAGATGCAGTTCAGTTTATAAGACAAAAAAGAAGGGGAGCGTTCAATTCCAAACAGCTGCTTTATTTGGAGAAATACCGACCTAAGATGCGATTACGCTTCAGAGATACCAATGGGCATTGCTGTGTTCAGTAGAAGGAAATGTAAACGAAGGCTGACTTGATTGTGCCATTTAGAGGGAACTCTTGGTACCTGGAAATGTGAATCTGGAATATTACCTGTGTCATCAAAGTAGTGATGGATTCAGTACTCCTCAACCACTCTCCTAATGATTGGAACAAAAGCAAACAAAAAAGAAATCTCTCTATAAAATGAATAAAATGTTTAAGAAAAGAGAAAGAGAAAAGGAATTAATTCAGTGAAGGATGATTTTGCTCCTAGTTTTGGAGTTTGAATTTCTGCCAGGATTGAATTATTTTGAAATCTCCTGTCTTTTTAAACTTTTTCAAAATAGGTCTCTAAGGAAAACCAGCAGAACATTAGCCTGTGCAAAACCATCTGTTTGGGGAGCACACTCTTCCATTATGCTTGGCACATAGATCTCCCTGTGGTGGGATTTTTTTTTTCCCTTTTTTTGTGGGGGAGGGTTGGTGGTATATTTTTCCCCTCTTTTTTCCTTCCTCTCCTACATCTCCCTTTTCCCCCGATCCAAGTTGTAGATGGAATAGAAGCCCTTGTTGCTGTAGATGTGCGTGCAGTCTGGCAGCCTTAAGCCCACCTGGGCACTTTTAGATaaaaaaaaaaaaaaaacaaaaaacaacaccaaaaaaaCAGCAGTGatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatataatataatatatatatatatatatatatTTTCCAGGTGGTTTTTAGTCTTTACTGATGAAAGGGTGTTCATGTTAGTTTCTTCAAAACCCTATCTAATACTAGGCAAAGTAGCCAAGAGCCTTTTGTTTTGTTTTTATTTTGATAAATTAGTGGAGAAATGGCATTTTAAGAGGAGTCTCTTCTCAACTTACCTGAGAGTCGAATTCTTCTCTTCCCTAACCAATGAAGCTAAGTGGTTATCCCAGAAACTTGTCTTCTAAAAGGGAGGACTCCAGGCCATCAATAAAGATGTCCAGGCAGTGAGCGTACTTTTTACACCCTGTAGAATTGTGGGCTGTAGCGTTACTCTGATTTTCTGTCTAGTATCAGAGAATGCTGGTAGCTTAAAATTTTTATTTTAGGACTTGTACTCTGAATTTTCAGGAACCGTCAAAGGAGCAGCAGCAAATTCACATATTTTCGACTTGAGAAATGCTTGTGGTATGTGTTTTCCAAACTGCCCCCTATATGTAAAGTTCAGTTTAACCACTGATTGCCTTGTTATTACTAGGTTTTTTGAGATTAAAAAAAAAAAATCCCTGGTTTAAAACCAACAATGATGCCTAGTGAGTATGTGTCCACAGGCCATAACAGGGTAGAAGAGAGACATCGTGCAACCCAATGAGTAGTGAAGGGACTGTGTTGCTTGTGAAGCGGTGTAGTAGCATTTTTGCAGATTCTTGGCTGGGTTTAGTGTACTGATCTAGAAAAGCTGTTTTTCTGCTCCTTTGTGGAAGGCAGTTATGATCAGGCTGCATGGACAAAGCAGGTAGAGGGGCACCATCAGGGGCTCTTGCACTATTTTCACCTCTAAATATTACGTACTCAGTAGTGCCCTGCTTCTAGGGCTCTGAATACGGGCTTAAAGTCATCTTGTCCTGCTGGAATTTGCTGTGCAGAGCCATAAGCCTCCCATTTTGTTAGCGTCAGCTAGGCCAATAGGAACAGACCGGGACCTTGTCTCACACTGATGATACCTCACATGTTGACCGGCTATGTGAACTGCCTATTTCCTATGCTGGAGTTTTGATTTTTAACTAAACGCAAATCTGTAGATTCTCTCCTCTCCCATCCCAGAAAACAAAACAAAATAATGCTTTTCGAAATTGTTTCTAGGACTTTAAAACATAATGGTATATCCAAAATTCTTTATTTCAGAATGCAACAATAGATTCCATTAATATAGACTCAAGATCAAAACAGCATACCTGCTAAGCTAAGATAGATGGTGTTGATTCCACTGGGTTTTGATCAATACAATAACAAACCTTTTTCCTTTGACATACTCTGAATTTTGTTGTTTGGGGGGAGGGGgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtgtgtgtgtgtgtgtgCACGCGCAGTGTCCATCAGTATCAGTGCCTGCCTGAGTTAGGAAAATTACATTCCTGGTTCTGTATTGAGGAGAAGGATGTATAAAGCAACATGAAACATTAGCCCTCCTTTTATTTTAAAGACTAATGTTAATTGTTCTTAAAACTGGATTTTTTTTCCTTAAAGCAATTTTTTTCTTTTCGATTTAATGAAGTATTGCTAGCTGAAGCCAGTTTGACATAGAGAGATGTCAGATTGATTTGAAAGGTGTGCAGCCTGATTTAAAACCAAACCCTGAACCCTTTTAAAGAACAATAAAACATATTTTACACGCTC |
| >NM_080391.4 |
| ccggctgcgcgcgcagcggtggtggtggcggcgcgatcggccgggctgtaaccgtcgtctgtccgggagcggctggagcggcagcggcggccgggcacggcgcgaggtgacgccacagggcagcggcggcagcggaggcagcggcggcagcaggagacgcagcggcggccgcagcagcagcagcAAGACGGACTCGTGGAGACGcgccgccgccgccgccgccgggccgggccgggtgtcgcgcgccgAGGCTGGGGGGGAGTCGTcgccgccgccgccaccgctaccgccgccgccgccgccgccgAGGTGACTGAGGAGAGAGGCGCCTCCTCGCTCCCGCCACCGCCGGACTTCAATGCCCAGTCCCCAGCTCGCCAGCGTTTTTCGTTGGAATATACGTTGCACATTTATGGCGATTCTGAGTGTGAGGGCAGACTTCTGCCAGGCTCAGCACAGCATTTTCGCTGACAAGTGAGCTTGGAGGTTCTATGTGCCATAATTAACATTGCCTTGAAGACTCCTGGACACCGAGACTGGCCTCAGAAATAGTTGGCTTTTTTTTTTTTTAATTGCAAGCATATTTCTTTTAATGACTCCAGTAAAATTAAGCATCAAGTAAACAAGTGGAAAGTGACCTACACTTTTAACTTGTCTCACTAGTGCCTAAATGTAGTAAAGGCTGCTTAAGTTTTGTATGTAGTTGGATTTTTTGGAGTCCGAAGGTATCCATCTGCAGAAATTGAGGCCCAAATTGAATTTGGATTCAAGTGGATTCTAAATACTTTGCTTATCTTGAAGAGAGAAGCTTCATAAGGAATAAACAAGTTGAATAGAGAAAACACTGATTGATAATAGGCATTTTAGTGGTCTTTTTAATGTTTTCTGCTGTGAAACATTTCAAGATTTATTGATTTTTTTTTTTCACTTTCCCCATCACACTCACACGCACGCTCACACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTGGAGATCTCCTATGAGAACATGCGTTTTCTGATAACTCACAACCCTACCAATGCTACTCTCAACAAGTTCACAGAGGAACTTAAGAAGTATGGAGTGACGACTTTGGTTCGAGTTTGTGATGCTACATATGATAAAGCTCCAGTTGAAAAAGAAGGAATCCACGTTCTAGATTGGCCATTTGATGATGGAGCTCCACCCCCTAATCAGATAGTAGATGATTGGTTAAACCTGTTAAAAACCAAATTTCGTGAAGAGCCAGGTTGCTGTGTTGCAGTGCATTGTGTTGCAGGATTGGGAAGGGCACCTGTGCTGGTTGCACTTGCTTTGATTGAATGTGGAATGAAGTACGAAGATGCAGTTCAGTTTATAAGACAAAAAAGAAGGGGAGCGTTCAATTCCAAACAGCTGCTTTATTTGGAGAAATACCGACCTAAGATGCGATTACGCTTCAGAGATACCAATGGGCATTGCTGTGTTCAGTAGAAGGAAATGTAAACGAAGGCTGACTTGATTGTGCCATTTAGAGGGAACTCTTGGTACCTGGAAATGTGAATCTGGAATATTACCTGTGTCATCAAAGTAGTGATGGATTCAGTACTCCTCAACCACTCTCCTAATGATTGGAACAAAAGCAAACAAAAAAGAAATCTCTCTATAAAATGAATAAAATGTTTAAGAAAAGAGAAAGAGAAAAGGAATTAATTCAGTGAAGGATGATTTTGCTCCTAGTTTTGGAGTTTGAATTTCTGCCAGGATTGAATTATTTTGAAATCTCCTGTCTTTTTAAACTTTTTCAAAATAGGTCTCTAAGGAAAACCAGCAGAACATTAGCCTGTGCAAAACCATCTGTTTGGGGAGCACACTCTTCCATTATGCTTGGCACATAGATCTCCCTGTGGTGGGATTTTTTTTTTCCCTTTTTTTGTGGGGGAGGGTTGGTGGTATATTTTTCCCCTCTTTTTTCCTTCCTCTCCTACATCTCCCTTTTCCCCCGATCCAAGTTGTAGATGGAATAGAAGCCCTTGTTGCTGTAGATGTGCGTGCAGTCTGGCAGCCTTAAGCCCACCTGGGCACTTTTAGATaaaaaaaaaaaaaaaacaaaaaacaacaccaaaaaaaCAGCAGTGatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatataatataatatatatatatatatatatatTTTCCAGGTGGTTTTTAGTCTTTACTGATGAAAGGGTGTTCATGTTAGTTTCTTCAAAACCCTATCTAATACTAGGCAAAGTAGCCAAGAGCCTTTTGTTTTGTTTTTATTTTGATAAATTAGTGGAGAAATGGCATTTTAAGAGGAGTCTCTTCTCAACTTACCTGAGAGTCGAATTCTTCTCTTCCCTAACCAATGAAGCTAAGTGGTTATCCCAGAAACTTGTCTTCTAAAAGGGAGGACTCCAGGCCATCAATAAAGATGTCCAGGCAGTGAGCGTACTTTTTACACCCTGTAGAATTGTGGGCTGTAGCGTTACTCTGATTTTCTGTCTAGTATCAGAGAATGCTGGTAGCTTAAAATTTTTATTTTAGGACTTGTACTCTGAATTTTCAGGAACCGTCAAAGGAGCAGCAGCAAATTCACATATTTTCGACTTGAGAAATGCTTGTGGTATGTGTTTTCCAAACTGCCCCCTATATGTAAAGTTCAGTTTAACCACTGATTGCCTTGTTATTACTAGGTTTTTTGAGATTAAAAAAAAAAAATCCCTGGTTTAAAACCAACAATGATGCCTAGTGAGTATGTGTCCACAGGCCATAACAGGGTAGAAGAGAGACATCGTGCAACCCAATGAGTAGTGAAGGGACTGTGTTGCTTGTGAAGCGGTGTAGTAGCATTTTTGCAGATTCTTGGCTGGGTTTAGTGTACTGATCTAGAAAAGCTGTTTTTCTGCTCCTTTGTGGAAGGCAGTTATGATCAGGCTGCATGGACAAAGCAGGTAGAGGGGCACCATCAGGGGCTCTTGCACTATTTTCACCTCTAAATATTACGTACTCAGTAGTGCCCTGCTTCTAGGGCTCTGAATACGGGCTTAAAGTCATCTTGTCCTGCTGGAATTTGCTGTGCAGAGCCATAAGCCTCCCATTTTGTTAGCGTCAGCTAGGCCAATAGGAACAGACCGGGACCTTGTCTCACACTGATGATACCTCACATGTTGACCGGCTATGTGAACTGCCTATTTCCTATGCTGGAGTTTTGATTTTTAACTAAACGCAAATCTGTAGATTCTCTCCTCTCCCATCCCAGAAAACAAAACAAAATAATGCTTTTCGAAATTGTTTCTAGGACTTTAAAACATAATGGTATATCCAAAATTCTTTATTTCAGAATGCAACAATAGATTCCATTAATATAGACTCAAGATCAAAACAGCATACCTGCTAAGCTAAGATAGATGGTGTTGATTCCACTGGGTTTTGATCAATACAATAACAAACCTTTTTCCTTTGACATACTCTGAATTTTGTTGTTTGGGGGGAGGGGgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtgtgtgtgtgtgtgtgCACGCGCAGTGTCCATCAGTATCAGTGCCTGCCTGAGTTAGGAAAATTACATTCCTGGTTCTGTATTGAGGAGAAGGATGTATAAAGCAACATGAAACATTAGCCCTCCTTTTATTTTAAAGACTAATGTTAATTGTTCTTAAAACTGGATTTTTTTTCCTTAAAGCAATTTTTTTCTTTTCGATTTAATGAAGTATTGCTAGCTGAAGCCAGTTTGACATAGAGAGATGTCAGATTGATTTGAAAGGTGTGCAGCCTGATTTAAAACCAAACCCTGAACCCTTTTAAAGAACAATAAAACATATTTTACACGCTC |