Summary

Gene Name	TM2D1
Specie	Homo sapiens
Full Name	TM2 domain containing 1
Also known as	BBP
Coordinate	chr1:61681046-61725141
Strand	-
Gene summary	The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Retrocopy(s) from TM2D1

Retroname	Coord	Strand	Genomic Region	ENSG
TM2D1P1	chr3:106325764-106325925	-	Intergenic	ENSG00000244652	UCSC

Expression

Transcript Sequences

>NM_032027.3

GAGAAAGTGTCGGTCTCCAAGATGGCGGCCGCCTGGCCGTCTGGTCCGTCTGCTCCGGAGGCCGTGACGGCCAGACTCGTTGGTGTCCTGTGGTTCGTCTCAGTCACTACAGGACCCTGGGGGGCTGTTGCCACCTCCGCCGGGGGCGAGGAGTCGCTTAAGTGCGAGGACCTCAAAGTGGGACAATATATTTGTAAAGATCCAAAAATAAATGACGCTACGCAAGAACCAGTTAACTGTACAAACTACACAGCTCATGTTTCCTGTTTTCCAGCACCCAACATAACTTGTAAGGATTCCAGTGGCAATGAAACACATTTTACTGGGAACGAAGTTGGTTTTTTCAAGCCCATATCTTGCCGAAATGTAAATGGCTATTCCTACAAAGTGGCAGTCGCATTGTCTCTTTTTCTTGGATGGTTGGGAGCAGATCGATTTTACCTTGGATACCCTGCTTTGGGTTTGTTAAAGTTTTGCACTGTAGGGTTTTGTGGAATTGGGAGCCTAATTGATTTCATTCTTATTTCAATGCAGATTGTTGGACCTTCAGATGGAAGTAGTTACATTATAGATTACTATGGAACCAGACTTACAAGACTGAGTATTACTAATGAAACATTTAGAAAAACGCAATTATATCCATAAATATTTTTTAAAAGAAACAGATTTGAGCCTCCTTGATTTTAATAGAGAACTTCTAGTGTATGGATTTAAAGATTTCTCTTTTTCATTCATATACCATTTTATGAGTTCTGTATAATTTTTTGTGGTTTTTGTTTTGTTGAGTTAAAGTATATTATTGTGAGATTTATTTAATAGGACTTCCTTTGAAAGCTGTATAATAGTGTTTCTCGGGCTTCTGTCTCTATGAGAGATAGCTTATTACTCTGATACTCTTTAATCTTTTACAAAGGCAAGTTGCCACTTGTCATTTTTGTTTCTGAAAAATAAAAGTATAACTTATTCACA