| Gene Name | Shc1 |
|
| Specie | Rattus norvegicus | |
| Full Name | SHC adaptor protein 1 | |
| Also known as | P66shc | |
| Coordinate | chr2:188745503-188757066 | |
| Strand | + | |
| Gene summary | Enables enzyme binding activity; epidermal growth factor receptor binding activity; and phosphotyrosine residue binding activity. Involved in several processes, including positive regulation of smooth muscle cell proliferation; positive regulation of vasoconstriction; and response to peptide hormone. Located in endosome membrane; nucleus; and plasma membrane. Part of Shc-EGFR complex. Used to study glomerulosclerosis. Biomarker of familial hyperlipidemia and hepatocellular carcinoma. Orthologous to human SHC1 (SHC adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022] |
| Retroname | Coord | Strand | Genomic Region | ENSG | |
|---|---|---|---|---|---|
| Shc1P1 | chr4:104311025-104314376 | + |
Intergenic |
N/A | UCSC |
| >NM_001164060.1 |
| GGGCTGGGCCAGGATGTGGTTTGAAACTGTCTAGGTCTGAGTTGGGAGAGCAGAGGTCACTTGTCCTTCGCCTCCCCAGGTCCTCTGTTATCACCCGGCTGCCGAGGTCAGACTAGGCTAAGGGTCTGGGGATGCCCCCTGCCTGGCCCCCTTGCCTGAATTGGCAGGGGGGCCGGGCCGGGCAGCAGCCCCCCTTCTCACCCCAGCCATGGATCTTCTACCCCCCAAGCCGAAGTACAACCCACTTCGGAATGAGTCTCTGTCATCGCTGGAGGAGGGGGCTTCAGGGTCTACTCCACCGGAGGAGCTGCCTTCCCCATCAGCCTCATCCCTGGGACCCATTCTGCCTCCTCTGCCGGGGGACGATAGCCCGACTACCCTGTGTTCCTTCTTTCCCCGGATGAGCAACTTGAAGCTGGCCAATCCTGCTGGGGGGCGCCTGGGACCTAAAGGGGAGCCAGGAAAAGCTGCAGAAGATGGGGAAGGGAGTGCAGGAGCAGCCCTTCGGGACTCAGGCCTCTTGCCCCTCCTCCAGGACATGAACAAGCTGAGTGGAGGCGGCGGGCGCAGGACTCGGGTAGAAGGGGGCCAGCTGGGGGGCGAGGAGTGGACCAGACACGGGAGCTTTGTCAATAAGCCCACACGAGGCTGGCTGCATCCCAACGACAAAGTCATGGGACCTGGGGTTTCCTACTTGGTTCGGTACATGGGTTGCGTGGAGGTCTTACAGTCAATGCGAGCCCTTGACTTCAATACCCGGACTCAGGTCACCAGGGAGGCTATCAGTTTGGTGTGTGAAGCTGTGCCTGGTGCCAAAGGGGCGATGAGGAGGAGAAAGCCCTGCAGCCGCCCACTCAGCTCTATCCTGGGAAGGAGTAACCTGAAGTTTGCTGGAATGCCGATCACTCTCACTGTGTCTACCAGCAGCCTTAACCTCATGGCAGCAGACTGCAAACAGATCATTGCCAACCATCACATGCAATCTATCTCATTCGCGTCTGGTGGGGATCCGGACACAGCTGAGTACGTTGCCTATGTTGCCAAAGACCCTGTGAATCAGAGAGCCTGCCATATCCTGGAGTGTCCTGAAGGACTTGCTCAGGACGTCATCAGCACCATCGGGCAGGCCTTTGAGTTGCGCTTCAAACAGTATCTCAGGAATCCACCCAAGCTGGTCACCCCCCATGACAGGATGGCTGGCTTTGATGGCTCAGCTTGGGATGAGGAGGAAGAAGAGCCCCCTGACCATCAGTACTACAATGACTTCCCAGGGAAGGAACCCCCTCTTGGTGGAGTGGTAGATATGAGGCTTCGGGAAGGGGCTGCTCGACCCACTCTGCCCAGTACCCAGATGCCCAGCCACTTGGGAGCTACACTGCCAATAGGGCAGCATGTTACAGGAGACCATGAAGTCCGTAAACAGATGCTGCCTCCACCACCGTGCCCAGGCAGAGAACTCTTCGATGATCCTTCCTATGTCAACATCCAGAATCTAGACAAGGCCCGGCAAGCTGGTGGTGGGGCTGGACCCCCAAATCCTTCTGTTAATGGCAGTGCACCCCGAGACCTCTTTGACATGAAGCCCTTCGAAGATGCACTCCGGGTGCCGCCAGCTCCCCAGTCCATGTCCATGGCTGAGCAGCTCCAAGGGGAGTCCTGGTTTCATGGGAAACTCAGCCGGCGGGAGGCTGAGGCGCTGCTGCAGCTCAACGGTGACTTCTTGGTGCGAGAGAGTACAACCACACCTGGCCAGTACGTGCTCACTGGTCTGCAGAGTGGGCAGCCCAAGCACTTGCTTCTGGTGGACCCTGAAGGTGTGGTTCGGACAAAGGATCACCGCTTTGAGAGTGTCAGTCACCTGATCAGCTACCACATGGACAATCACTTACCCATCATCTCTGCAGGCAGTGAGCTGTGTCTACAGCAACCTGTGGATCGAAAAGTGTGATCCTTCTTAGCCTCTCCTGGAGGACGCTCTCCACTCCCTTCTACCGTGTACTCGTGGGGCCGCTGCTTGGTGGGAACTGAGCGGCAAGGACACGGCTTTAGTGCCCACTTGAGAGAGGATTTTTAGGAGCCTGGGAAAGCATCCTTCTTCTGCCCAAACCTCACCAAAGTATTAATGTGCAGAGTGGTCCCTTGTCTGGGCCTTGCCTGTGCCAACCTGATGCCCTTCCCCCAAAAGGGTGGGTTTTATAATGGAAAATACCCTGTGGTGTTAGACCCAGTGGAGTAATTGCCCTTTGGGGGAAGGGAAATAATCATACCTCTGGTTTACTCCTGGTCTTCAGGGTACCCCAGACCCCTTTTAACATATCCTACTCCCTATGCATCTCCTTAAAACTTTGTGCCTTCGACTATCATAGGTCTGCAGATACTTTATGCAGAGTTCTCAGGCTCTTCAGATGTGGACAGGGGTTACTGACACCTTGACTTCTGGAACCCTGTTCTGCTCAGCATCCCTTCCTGTGTCTGGGGAGAATAGGGCAGGAGTGGCCACCATCTCCTCTGCTTTTGGATGTACAGCCCTTTAAAGGTTGCCCCAGgccaggatgtggtgacacatgcctttaatcactgcactcaggaggcagaggcaggaggatttgtgaagctaccctggcctacaacagtgagttccagtacagccagggctatggagagaggacctgtttccaaaaaaccaaaAAGAACAATTACCCCCAGAGCCTTGGGGAGGGGCAGGATTGGACTCATCTTGCTCAGTGCCTCCTGACCTCAATGCCTTCCTTCCAAGGGGTCTGTATACATTTCTTAAGCCCACCCCTCCCATGTTTGCATGTGTGTTATAGTCTACAGCCAAAGTGTAGCCGTTACTGTAACCCCATCAGTCTCCCTCTTTTGGGACAGGTGTGTGTGGCTCACTTGGGCCTCCAGTATGTGTGCAGTCCAAGTGGGTTTTATGGAGGCCTGGAGACTGAAGCAGTAGACAATCCCCAATACCATTTGCAGGTCTGGAACTGCTCGCTCGctctctctctctctctctctctctctctctctctctctctctctctctctctctTTTTTATAGAAAAAAAAAAGTATACATTTTAGGGCTGTAGATTTATTTTCCTAGTTTTGTTTTTCGTTGCTGACTTTTGAGCACAGAATTATGATAATCAATTACATTTATACATCACCTCGTTGACGTTTCCAAACTTTTTTTTTTAAAACATCTTGTTGGAATTTTACTCCCTGGCCTAACTAGGACAGGGTCCCGTACCTCCCCCTACCCCCCGCCCCCGCCTCCTTCTTCCTCAAGACACCTGAGCAGAAATTTGGCTGAACAGTGTTGTGGAATTATGTGATAGCTTTAGATCCTCCCTTCTGCTTGAGGGCAGATGCGGCCAGGCCAGCACAGAAACCTTGCAAGCTTACTCTGAAGGCTTTCTGGACAAGGAGTGGTCGACTGGATTTCAGTCTTGGCTGTCGCCTATTTTTGGTTTGGATGTCTTATACCAAAGGGAAATAGTCTTCATTAAAGTCCGTATTTCTTCTA |